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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Subact-Forte 3 gm Injection is used to treat various bacterial infections such as respiratory tract (lungs) infection, urine infection, blood infection, meningitis (inflammation of the brain and spinal cord), gonorrhoea (sexually transmitted disease), skin, abdominal, bone, and joint infections. It contains Cefoperazone and Sulbactam, which works by preventing the formation of bacterial cell covering necessary for their survival. Thereby, kills the bacteria. It may cause diarrhoea, allergic reaction, abnormal liver function tests, and anaemia (low number of red blood cells). Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Manufacturer/Marketer :

Medimarck Biotech

Consume Type :

Parenteral

Expires on or after :

Return Policy :

Not Returnable

About Subact-Forte 3 gm Injection

Subact-Forte 3 gm Injection belongs to the group of medicines called antibiotics used to treat various bacterial infections such as respiratory tract (lungs) infection, urine infection, blood infection, meningitis (inflammation of the brain and spinal cord), gonorrhoea (sexually transmitted disease), skin, abdominal, bone, and joint infections. Bacterial infections are caused due to the multiplication of harmful bacteria inside or on the body. Infectious or harmful bacteria can make you sick and reproduce quickly in your body. These harmful bacteria produce chemicals known as toxins, which can damage tissue and make you sick. Subact-Forte 3 gm Injection does not work against infections caused by the virus, including cold and flu.

Subact-Forte 3 gm Injection is a combination of two antibiotics, namely: Cefoperazone (cephalosporin antibiotic) and sulbactam (beta-lactamase inhibitor). Cefoperazone works by preventing the formation of bacterial cell covering, which is necessary for their survival. Thereby, kills the bacteria. On the other hand, sulbactam works by decreasing bacterial resistance and enhancing the activity of cefoperazone against the bacteria. Together, Subact-Forte 3 gm Injection helps to treat bacterial infections.

You may experience diarrhoea, allergic reaction, abnormal liver function tests, and anaemia (low number of red blood cells). Most of these side effects of Subact-Forte 3 gm Injection do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Before starting Subact-Forte 3 gm Injection, please inform your doctor if you have any allergy (against any antibiotic), kidney or liver problems. Do not take Subact-Forte 3 gm Injection on your own as self-medication may lead to antibiotic-resistance in which antibiotics fail to act against specific bacterial infections. Consult your doctor before taking Subact-Forte 3 gm Injection if you are pregnant or planning for pregnancy. Avoid taking Subact-Forte 3 gm Injection if you are breastfeeding as Subact-Forte 3 gm Injection may pass into breast milk. Avoid alcohol consumption while taking Subact-Forte 3 gm Injection to prevent unpleasant side-effects.

Uses of Subact-Forte 3 gm Injection

Subact-Forte 3 gm Injection is used in the treatment of bacterial infections. The detailed uses of Subact-Forte 3 gm Injection are as follows:

  • Treatment of Bacterial Infections: Subact-Forte 3 gm Injection is effective against a wide range of bacterial infections, including those affecting the respiratory tract, urinary tract, skin, and soft tissues.
  • Management of Intra-Abdominal Infections: Subact-Forte 3 gm Injection is used to treat severe intra-abdominal infections, such as peritonitis and abscesses.
  • Septicemia Treatment: Subact-Forte 3 gm Injection is prescribed for managing septicemia, a life-threatening condition caused by harmful bacteria in the bloodstream.
  • Bone and Joint Infections: Subact-Forte 3 gm Injection is also used in treating severe infections of bones and joints, such as osteomyelitis and septic arthritis.

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Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication, to improve effectiveness.
  • Subact-Forte 3 gm Injection will be administered by a healthcare professional.
  • Do not self-administer it.

Key Benefits

Subact-Forte 3 gm Injection belongs to the group of medicines called antibiotics used to treat various bacterial infections such as respiratory tract (lungs) infection, urine infection, blood infection, meningitis (inflammation of the brain and spinal cord), gonorrhoea (sexually transmitted disease), skin, abdominal, bone, and joint infections. Subact-Forte 3 gm Injection is a combination of two antibiotics, namely: Cefoperazone (cephalosporin antibiotic) and sulbactam (beta-lactamase inhibitor). Cefoperazone works by preventing the formation of bacterial cell covering, which is necessary for their survival. Thereby, kills the bacteria. On the other hand, sulbactam works by decreasing bacterial resistance and enhancing the activity of cefoperazone against the bacteria. Together, Subact-Forte 3 gm Injection helps to treat bacterial infections.

How Subact-Forte 3 gm Injection Works

Subact-Forte 3 gm Injection is a combination of two antibiotics, namely: Cefoperazone (cephalosporin antibiotic) and sulbactam (beta-lactamase inhibitor). Cefoperazone works by preventing the formation of bacterial cell covering, which is necessary for their survival. Thereby, kills the bacteria. On the other hand, sulbactam works by decreasing bacterial resistance and enhancing the activity of cefoperazone against the bacteria. Together, Subact-Forte 3 gm Injection helps to treat bacterial infections.

Storage

Store in a cool and dry place away from sunlight
  • Managing a low platelet count (thrombocytopenia) caused by medication usage requires a multi-step approach. Here are some steps to help manage the condition:
  • Inform your doctor about your low platelet count and medication usage. They will assess the situation and guide the best course of action.
  • Your doctor may recommend adjusting or stopping the medication that is causing a low platelet count. This could involve switching to alternative medication or reducing the dosage.
  • Monitor your platelet count regularly through blood tests to track any changes. This will help the doctor determine the effectiveness of the treatment plan.
  • If an underlying condition, such as infection or inflammation, contributes to the low platelet count, your doctor will treat it.
  • In some cases, alternative treatments like platelet transfusions or medications that stimulate platelet production may be necessary.
  • Avoid risky activities and certain medications; eat a balanced diet with plenty of water to reduce bleeding risk and boost overall health.
  • If you experience severe bleeding or bruising, seek emergency medical attention immediately.
  • Maintain a healthy diet with fruits, whole grains, and vegetables.
  • Include easy-to-digest and antioxidant-rich food in your diet.
  • Drink plenty of water and unsweetened liquids.
  • Limit sugary foods, alcohol, refined carbs and fried foods.
Here are the few steps for dealing with itching caused by drug use:
  • Report the itching to your doctor immediately; they may need to change your medication or dosage.
  • Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
  • Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
  • Try not to scratch, as this can worsen the itching and irritate your skin.
  • If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
  • Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Managing Medication-Triggered Thrombophlebitis (Inflammation of a vein): A Step-by-Step Guide:
  • If you have symptoms such as pain, swelling, redness, or warmth in your veins after taking medication, contact your doctor right once. Share information about your symptoms, medication regimen, and medical history.
  • Your doctor will then assess your medication regimen to determine if it's contributing to the thrombophlebitis. This assessment will help identify the best course of action to manage your condition and prevent further complications.
  • Your doctor may suggest certain diet and lifestyle changes to help manage your condition. This may include increasing your intake of foods rich in omega-3 fatty acids, staying hydrated, exercising regularly, and maintaining a healthy weight. Your doctor may also advise medications to reduce inflammation, prevent blood clots, or manage pain if necessary.
  • If your condition does not improve or persists, consult your doctor and report your condition. Your doctor will assess your progress, adjust your treatment plan if necessary, and provide appropriate advice to ensure the best possible outcome.

What if I have taken an overdose of Subact-Forte 3 gm Injection

The overdose of Subact-Forte 3 gm Injection is unlikely as it is administered by a doctor. However, if you suspect any adverse reactions or unusual symptoms while on treatment with Subact-Forte 3 gm Injection, please inform your doctor immediately.

Drug Warnings

After taking Subact-Forte 3 gm Injection if you have allergy-like symptoms including rash, swelling of the face/lips/throat, difficulty in breathing, or tightness in the chest, immediately contact your doctor. Do not take Subact-Forte 3 gm Injection if you have an allergy to Subact-Forte 3 gm Injection, cephalosporins penicillin class of antibiotics as it may cause a skin rash, itching, and difficulty in breathing. People having liver disease or jaundice (yellowing of skin/eye) should not take Subact-Forte 3 gm Injection, as it can damage your liver severely. You may have diarrhoea in some cases which can be managed by taking it with any probiotics and plenty of fluids. Do not take antacids along with Subact-Forte 3 gm Injection; maintain a gap of 2-3 hours between both. Avoid alcohol consumption while taking Subact-Forte 3 gm Injection to prevent unpleasant side-effects. Subact-Forte 3 gm Injection may cause dizziness, so be cautious while driving. Inform your doctor about all the medicines you are taking and about your health condition to rule out any unpleasant side-effects.

Drug-Drug Interactions

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CefoperazoneBCG vaccine
Critical

Drug-Drug Interactions

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CefoperazoneBCG vaccine
Critical
How does the drug interact with Subact-Forte 3 gm Injection:
When BCG vaccine is used with Subact-Forte 3 gm Injection, its effectiveness may be reduced.

How to manage the interaction:
Taking Subact-Forte 3 gm Injection with BCG vaccine is not recommended, but can be taken together if prescribed by a doctor. However, consult your doctor if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor
How does the drug interact with Subact-Forte 3 gm Injection:
Taking Subact-Forte 3 gm Injection and Rifampicin together may increase the risk of bleeding.

How to manage the interaction:
Although there is an interaction between Subact-Forte 3 gm Injection and rifampicin, they can be taken together if prescribed by a doctor. However, if you experience vomiting, blood in your urine or stools, headache, dizziness, or weakness, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Probiotics should be taken after taking the full course of Subact-Forte 3 gm Injection in order to restore some healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut, kombucha, and kimchi can help to restore the good bacteria of the intestine.

  • Include more fibre-enriched food in your diet, as it can be easily digested by your gut bacteria, which helps stimulate their growth. Thus, fibre-rich foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains like whole-grain bread, brown rice should be included in your diet.

  • Avoid intake of alcoholic beverages with Subact-Forte 3 gm Injection as it can make you dehydrated and may affect your sleep. This can make it harder for your body to aid the Subact-Forte 3 gm Injection in fighting off infections.

Habit Forming

No

Therapeutic Class

[ANTI- BACTERIALS]

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Alcohol

Safe if prescribed

Avoid consuming alcohol while taking Subact-Forte 3 gm Injection as it cause increased side effects.

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Pregnancy

Consult your doctor

Please consult your doctor if you are pregnant, your doctor will prescribe Subact-Forte 3 gm Injection only if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

A small amount of Subact-Forte 3 gm Injection may pass into breast milk. Avoid taking Subact-Forte 3 gm Injection if you are breastfeeding unless prescribed.

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Driving

Safe if prescribed

Subact-Forte 3 gm Injection may cause dizziness in some people, so it may affect your ability to drive.

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Liver

Consult your doctor

Dose adjustment may be needed. Please consult your doctor before taking Subact-Forte 3 gm Injection if you have liver impairment/liver disease.

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Kidney

Consult your doctor

Dose adjustment may be needed. Please consult your doctor if you have any concerns regarding this or if you have kidney impairment/kidney disease before taking Subact-Forte 3 gm Injection.

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Children

Safe if prescribed

For children, Subact-Forte 3 gm Injection is safe, Dose needs to be adjusted and recommended by a doctor.

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Heart

Please inform your doctor if you have any pre-existing heart problems

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Geriatrics

Consult your doctor

Limited information available for use of Subact-Forte 3 gm Injection in elderly patients. Please consult your doctor.

FAQs

Subact-Forte 3 gm Injection is used to treat various bacterial infections such as respiratory tract (lungs) infection, urine infection, blood infection, meningitis (inflammation of the brain and spinal cord), gonorrhoea (sexually transmitted disease), skin, abdominal, bone, and joint infections.

No, do not stop taking Subact-Forte 3 gm Injection before completing the full course of treatment. You may start feeling better before the infection is completely cured. But, it is important to take this medicine for the full duration advised by your doctor.

Inform your doctor if you do not feel better even after finishing the full course of treatment. You must also inform your doctor if the symptoms get worse while using this medicine.

Usually, Subact-Forte 3 gm Injection starts working soon after taking it. Though, it may take a few days to kill all the dangerous bacteria and make you feel better.

Subact-Forte 3 gm Injection may cause Clostridium difficile-associated diarrhoea (CDAD). Treatment with antibiotics alters the normal flora leading to overgrowth of Clostridium difficile; this causes diarrhoea. Drink lots of fluids and eat food rich in fibre if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience prolonged diarrhoea with abdominal pain, stop taking Subact-Forte 3 gm Injection and consult your doctor. Do not take anti-diarrheal medicine on your own.

Yes, Subact-Forte 3 gm Injection is known to cause stomach upset. To avoid these side effects please take Subact-Forte 3 gm Injection with a meal. Also, Subact-Forte 3 gm Injection should be taken at evenly spaced intervals to avoid any unpleasant side effects and for best results.

It's generally not recommended to consume alcohol while taking Subact-Forte 3 gm Injection, as it can increase gastrointestinal issues, enhance sedative effects, and interfere with the antibiotic's effectiveness. Consult your doctor for personalized advice.

Subact-Forte 3 gm Injection is a combination antibiotic medication used to treat various bacterial infections.

Subact-Forte 3 gm Injection typically starts working within 1-2 hours after administration, but it may take 2-5 days to notice significant improvement in symptoms. The full effect of the treatment may be seen after completing the entire course of antibiotics, usually 7-14 days.

Be patient, as it may take time for the infection to clear. If your symptoms don't improve or worsen over time, consult your doctor for further guidance.

Common side effects of Subact-Forte 3 gm Injection include diarrhea, allergic reactions, abnormal liver function tests, and anemia. Most of these side effects are temporary and resolve on their own. However, if they persist, it's essential to consult your doctor for proper evaluation and guidance.

Country of origin

India

Manufacturer/Marketer address

B/209, “Shivalik Yash”, IInd Floor, Opp. Shashtrinagar BRTS Bus Stop, 132 Ft. Ring Road, Naranpura, Ahmedabad – 380013 Gujarat (INDIA)
Other Info - SUB0070

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