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Sulbact 250 mg/125 mg Injection is used to treat several types of bacterial infections. It contains Ampicillin (a penicillin antibiotic) and Sulbactam (a beta-lactamase inhibitor). Ampicillin is a penicillin antibiotic that treats the infection by killing the bacteria. Sulbactam is a beta-lactamase inhibitor. It broadens the spectrum of antibacterial activity by inhibiting the action of beta-lactamase, an enzyme produced by bacteria that can destroy antibiotics.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Consume Type :

Parenteral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Sulbact 250 mg/125 mg Injection

Sulbact 250 mg/125 mg Injection is a prescription antibiotic injection used to treat a wide variety of serious bacterial infections. It works by targeting and destroying bacteria in different parts of the body, such as the lungs, skin, stomach, and female reproductive organs. Doctors typically reserve this medicine for moderate to severe infections that require fast-acting treatment.

Because this medication is injected directly into a vein or muscle, it is usually given at specific, regular intervals to keep a steady amount of medicine in your body. To support your body's healing process during treatment, it is highly beneficial to drink plenty of fluids and get extra rest. Eating a balanced diet rich in vitamins also helps your immune system recover from the infection.

While taking this medicine, some patients may experience mild side effects like nausea or slight redness where the needle went in. However, you must contact your doctor immediately if you experience severe diarrhoea, extreme stomach cramping, or signs of a serious allergic reaction. Monitoring your body's response helps ensure your safety throughout the course of treatment.

Talk to your doctor before receiving this injection if you have kidney disease, asthma, or a history of bowel inflammation. Do not take this if you have ever had a severe allergic reaction to penicillin or similar antibiotic medications. Your doctor will evaluate your medical history to ensure this treatment is safe for you.

Let your doctor know about all other medications you use, as some drugs can affect how this injection works or increase the risk of side effects. It is also important to consult your healthcare provider if you are pregnant, breastfeeding, or managing health conditions as an older adult. Avoid drinking alcohol during treatment to prevent putting extra stress on your liver and stomach.

Uses of Sulbact 250 mg/125 mg Injection

Sulbact 250 mg/125 mg Injection is used to treat a wide variety of serious bacterial infections. The detailed uses of Sulbact 250 mg/125 mg Injection are as follows:

  • Intra-abdominal infections: Sulbact 250 mg/125 mg Injection helps clear bacterial infections inside the stomach area, including peritonitis, by stopping the growth of harmful bacteria.
  • Skin and skin structure infections: It effectively treats deep skin tissue infections, helping to resolve severe swelling, redness, and pain.
  • Gynaecological infections: This medicine targets bacteria responsible for pelvic infections, helping to protect reproductive organs from damage.
  • Bone and joint infections: It penetrates deep into bone and joint tissues to clear bacterial colonies and promote healing.

Key Benefits

This medication is highly effective when your body is fighting off a serious bacterial illness. Because it is injected directly, it enters your bloodstream quickly to provide fast relief from severe symptoms like fever and pain.

  • Rapid action: By bypassing the digestive system, it starts working immediately to stop the spread of infection throughout the body.
  • Overcomes bacterial resistance: The dual-action formula ensures that even bacteria that have developed defences against standard antibiotics are successfully destroyed.
  • Fosters complete recovery: It helps clear deep-seated infections thoroughly, reducing the risk of the infection returning or causing long-term health complications.

Directions for Use

  • The dose of Sulbact 250 mg/125 mg Injection depends on the type and severity of the infection, as well as the patient’s medical condition.
  • Sulbact 250 mg/125 mg Injection is administered by a healthcare professional through an intravenous (IV) injection or infusion in a hospital or clinical setting. The healthcare provider will determine the appropriate dosage and administration rate.
  • Do not self-administer
  • Make sure to inform your doctor of any allergies, especially to any antibiotics.

How Sulbact 250 mg/125 mg Injection Works

Sulbact 250 mg/125 mg Injection is a combination medicine containing two active components that work together to defeat bacteria. The first component, ampicillin, is a penicillin-type antibiotic. It works by interfering with the bacteria's ability to build their protective outer cell walls, which ultimately causes the bacterial cells to burst and die. The second component, sulbactam, acts as a shield. Many types of bacteria produce a special enzyme designed to destroy antibiotics before they can work. This second component permanently attaches to and disables these enzymes. By neutralising the bacterial defences, it allows the antibiotic component to do its job safely and effectively.
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Alcohol

Consult your doctor

The interaction of Sulbact 250 mg/125 mg Injection with alcohol is unknown. If you have any concerns, please discuss them with your doctor.

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Pregnancy

Consult your doctor

Limited data is available on the effect of Sulbact 250 mg/125 mg Injection in pregnancy. Hence, if you are pregnant or planning for pregnancy, inform your doctor before receiving Sulbact 250 mg/125 mg Injection. Your doctor may prescribe this medicine only if clearly needed.

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Breast Feeding

Caution

Low concentrations of Sulbact 250 mg/125 mg Injection may be excreted in breast milk. Therefore, Sulbact 250 mg/125 mg Injection should be used with caution if you are breastfeeding.

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Driving

Caution

It is unknown whether Sulbact 250 mg/125 mg Injection affects your ability to drive. However, avoid driving if you experience any symptoms affecting your driving ability.

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Liver

Consult your doctor

If you have a pre-existing or a history of liver disease, inform your doctor before receiving Sulbact 250 mg/125 mg Injection. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Consult your doctor

If you have a pre-existing or a history of kidney diseases, inform your doctor before receiving Sulbact 250 mg/125 mg Injection. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Consult your doctor

The safety and effectiveness of Sulbact 250 mg/125 mg Injection in children aged one year and above have been established. However, it is administered by a doctor or nurse.

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Heart

Consult your doctor

Please consult your doctor before using Sulbact 250 mg/125 mg Injection if you have pre-existing heart problems. Your doctor will prescribe Sulbact 250 mg/125 mg Injection if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Please consult a doctor before administering Sulbact 250 mg/125 mg Injection to geriatric patients. Your doctor will prescribe Sulbact 250 mg/125 mg Injection if the benefits outweigh the risks.

What if I have taken an overdose of Sulbact 250 mg/125 mg Injection

If you suspect an overdose, or if someone has accidentally injected too much of this medicine, seek emergency medical attention immediately. Symptoms of a severe overdose may include seizures, severe agitation, or extreme muscle twitching.

Diet & Lifestyle Advise

  • Stay well-hydrated: Drink plenty of water and clear broths throughout your treatment. This helps your kidneys process and clear the medication from your body efficiently.
  • Rest to recover: Allow your body to rest as much as possible. Sleep supports your immune system in fighting off the underlying infection.
  • Support your gut health: Antibiotics can disrupt the natural balance of bacteria in your stomach. Consider eating yoghurt with active cultures or taking a probiotic supplement after completing your antibiotic course, but discuss this with your doctor first.
  • Avoid alcohol: Do not drink alcohol while receiving this medication. Alcohol can weaken your immune system and increase your risk of experiencing stomach upset or liver strain.
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How Soon It Starts Working

The time required for Sulbact 250 mg/125 mg Injection to start to work: The effect of Sulbact 250 mg/125 mg Injection can be seen within 15 to 30 minutes after IV administration. The time for which the effects of Sulbact 250 mg/125 mg Injection last: The effect of Sulbact 250 mg/125 mg Injection can last for approximately 6 hours.

What if you forget to take Sulbact 250 mg/125 mg Injection

If you miss a dose, contact your doctor or pharmacist right away for instructions. If you are receiving this treatment at home and remember your missed dose close to the scheduled time, inject it as soon as possible. However, if it is almost time for your next scheduled injection, skip the missed dose and return to your regular schedule. Do not double the dose to make up for a missed one.

Storage

•Store the dry, unmixed vials of Sulbact 250 mg/125 mg Injection at controlled room temperature, between 20°C and 25°C (68°F to 77°F).

Drug Warnings

  • Check the liquid: Always inspect the mixed solution before injecting it. The liquid should be clear and free of visible particles; do not inject it if it is cloudy or discoloured.
  • Rotate injection sites: If you are receiving this medicine as an injection into a muscle, make sure to rotate the site of injection each time to reduce muscle soreness and tissue scarring.
  • Practice needle safety: Never reuse needles, syringes, or vials. Place all used sharp objects immediately into a designated puncture-proof sharps container.
  • Monitor your skin: Stop using the medication and contact your doctor immediately if you develop a skin rash, peeling skin, or blisters.
  • Complete the full course: Even if you start feeling completely healthy after a few days, do not stop taking the medicine until you have finished the entire duration prescribed by your doctor.

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  • Blood thinners (such as warfarin): Taking Sulbact 250 mg/125 mg Injection may increase the risk of bleeding. Your doctor may need to monitor your blood clotting tests more frequently.
  • Gout medications (such as allopurinol): Combining these medicines can increase your risk of developing a severe allergic skin rash
  • Probenecid: This medication can slow down how quickly your kidneys remove Sulbact 250 mg/125 mg Injection from your body, leading to higher levels of the antibiotic in your blood.
  • Other antibiotics: Mixing this injection in the same IV line with other antibiotics (like aminoglycosides) can make both medications less effective.

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  • No clinically significant food interactions are known with Sulbact 250 mg/125 mg Injection when used as directed.

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Habit Forming

No

Therapeutic Class

[ANTIBIOTIC COMBINATION]

FAQs

Sulbact 250 mg/125 mg Injection is used to treat Bacterial infections.
Sulbact 250 mg/125 mg Injection is a combination of two antibiotics: Ampicillin and Sulbactam. Ampicillin works by interfering with the formation of the bacterial cell wall (a protective covering) that is necessary for their survival. It damages the bacterial cell wall and kills bacteria. Sulbactam works by blocking beta-lactamase, an enzyme produced by bacteria to inactivate antibiotics. Thus, it prevents bacteria from destroying Ampicillin.
Sulbact 250 mg/125 mg Injection may be used to treat pneumonia (lung infection) caused by bacteria. Sulbact 250 mg/125 mg Injection is an antibiotic that kills bacteria and prevents the spread of infection. But it should be used only when prescribed by a doctor.
Sulbact 250 mg/125 mg Injection may cause diarrhoea as a common side effect. However, if the condition persists or worsens, or you notice blood or mucus in your stools, inform your doctor immediately.
Ampicillin in Sulbact 250 mg/125 mg Injection may reduce the effectiveness of oral contraceptives. Therefore, you may be advised to use an alternate or additional method of contraception while on treatment with Sulbact 250 mg/125 mg Injection. However, please consult your doctor before using other medicines with Sulbact 250 mg/125 mg Injection.
Yes, you can receive this injection at home if your healthcare provider decides it is safe. A nurse will train you or a caregiver on how to mix, inject, and safely store the medicine. Talk to your doctor to see if home injection is a suitable option for you.
This medication should only be used during pregnancy or breastfeeding if it is clearly needed and prescribed by a doctor. It can pass into breast milk in small amounts. Talk to your doctor to discuss the potential benefits and risks.
It is highly recommended to avoid alcohol while your body is fighting a serious infection. Alcohol can weaken your immune system and increase the likelihood of side effects like stomach upset and dizziness. Talk to your doctor for personalised advice.
No, this medication is an antibiotic designed specifically to treat bacterial infections. It will not work against viral infections like the common cold, flu, or COVID-19. Talk to your doctor if you are unsure about the cause of your illness.
If you have had a severe allergic reaction, such as swelling or trouble breathing, to penicillin or other similar antibiotics, you should not take this medicine. Always inform your healthcare team of any allergies before starting a new treatment. Talk to your doctor about alternative options.
Stopping your antibiotic treatment early can leave behind the strongest bacteria, which can then multiply and cause the infection to return. These remaining bacteria may also become resistant to future antibiotic treatments. Talk to your doctor if you are considering stopping your therapy early.

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Country of origin

India
Other Info - SU38049
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