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Sulpress Injection is used to treat digestive conditions such as dyspepsia, GERD, IBS, nausea, and vomiting, as well as certain mental health conditions. It works by improving gut movement and blocking dopamine activity in the brain. Common side effects include abdominal pain, drowsiness, constipation, weight gain, tiredness, and weakness.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
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More about the Product

Consume Type :

Parenteral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Sulpress Injection

Sulpress Injection is used to treat gastrointestinal problems such as indigestion, delayed stomach emptying in diabetes, GERD, IBS, nausea, and vomiting when oral treatment is not suitable. It may also be used for certain mental health conditions, including schizophrenia, anxiety, depression, and Tourette’s syndrome.

Sulpress Injection contains Levosulpiride, which improves gut movement and stomach emptying, helping food pass smoothly through the digestive system. It also blocks dopamine activity in the brain, supporting better mood, behaviour, and thoughts.

Sulpress Injection is given by a qualified healthcare professional. Do not self-administer. Abdominal pain, drowsiness, constipation, weight gain, tiredness, and weakness may occur. Consult your doctor if symptoms persist.

Inform your doctor if you have intestinal blockage or perforation. Sulpress Injection is not recommended during pregnancy or breastfeeding. Always inform your doctor about your medical conditions and other medicines you are taking.

Uses of Sulpress Injection

Sulpress Injection is used to treat various gastrointestinal and psychiatric conditions. The detailed uses of Sulpress Injection are as follows:

  • Treatment of gastrointestinal disorders: Sulpress Injection is effective in managing conditions like dyspepsia (indigestion), gastroesophageal reflux disease (GERD), irritable bowel syndrome (IBS), and diabetic gastroparesis by improving stomach motility and reducing acid reflux symptoms.
  • Relief from nausea and vomiting: Sulpress Injection helps control nausea and vomiting by acting on dopamine receptors in the gut and brain.
  • Management of psychiatric conditions: Sulpress Injection is used to treat psychosis, schizophrenia, depression, and anxiety by balancing dopamine levels in the brain.
  • Treatment of Tourette’s syndrome: Sulpress Injection helps manage vocal tics and motor symptoms associated with this neurological disorder.

Key Benefits

Sulpress Injection is a prokinetic and antipsychotic agent that provides the following medicinal benefits:

For gastrointestinal disorders:

  • Beneficial in situations where oral digestive medicines are not feasible or ineffective.
  • Effective in treating indigestion, acid reflux, irritable bowel syndrome, and diabetic gastroparesis.
  • Enhances the contractions of the stomach and intestines, helping food move smoothly through the gut.
  • Promotes faster stomach emptying, which helps reduce indigestion, bloating, and fullness.

For nausea and vomiting:

  • Helps prevent nausea and vomiting by calming the part of the brain (chemoreceptor trigger zone) that triggers these symptoms.

For psychiatric conditions:

  • Helps manage symptoms of schizophrenia, psychosis, depression, and anxiety.
  • Improves mood, behaviour, and thinking by normalising the activity of dopamine in the brain.

For Tourette’s syndrome:

  • Helps control unwanted movements and vocal sounds (tics) by regulating abnormal dopamine signalling in the brain.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safe and effective use.
  • Sulpress Injection will be administered by the doctor.
  • Do not self-administer.

How Sulpress Injection Works

Sulpress Injection contains Levosulpiride, which enhances the contractions in the gut and improves stomach emptying. This improves food movement through the gut, thereby treating disorders related to the stomach and intestines. Additionally, Sulpress Injection works by blocking dopamine activity in the brain, thereby improving mood, behaviour, and thoughts in psychotic disorders.
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Sulpress Injection to prevent unpleasant side effects.

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Pregnancy

Unsafe

Avoid taking Sulpress Injection if you are pregnant. Please consult your doctor if you have any concerns regarding this.

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Breast Feeding

Unsafe

Avoid breastfeeding while on treatment with Sulpress Injection. Consult your doctor if you have any concerns.

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Driving

Caution

Sulpress Injection may cause drowsiness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Consult your doctor before taking Sulpress Injection if you have a liver impairment or liver problems.

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Kidney

Caution

Consult your doctor before taking Sulpress Injection if you have kidney impairment or kidney problems.

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Children

Caution

Limited information is available regarding the usage of Sulpress Injection in children. Please consult a doctor.

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Heart

Caution

Sulpress Injection should be used with caution in heart patients, as it can alter heart rate and may trigger irregular rhythms. Always consult your doctor to assess risks and determine if it's appropriate for your condition.

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Geriatrics

Caution

Sulpress Injection can be used in geriatric patients, but older adults may be more sensitive to side effects like dizziness, drowsiness, or heart rhythm changes. It's best administered under medical supervision with appropriate dose adjustments.

What if I have taken an overdose of Sulpress Injection

Sulpress Injection is administered by a health care professional in a hospital setting. Hence, the chances of overdose are less. Your doctor may take necessary measures if an overdose is suspected.

Diet & Lifestyle Advise

For gastrointestinal disorders:

  • Eat smaller meals more often.
  • Avoid smoking, alcohol, and trigger foods (spicy, fatty, chocolate, citrus, tomato, onion, garlic, tea, soda).
  • Avoid lying down immediately after eating.
  • Avoid tight-fitting clothes.
  • Maintain a healthy weight through regular exercise.
  • Practice relaxation techniques like yoga or meditation to reduce stress.
  • Avoid sitting continuously, as it may trigger acidity.
  • Take short breaks by doing brisk walking or stretching.

For psychiatric disorders:

  • Maintain a healthy diet and exercise regularly.
  • Regularly attend therapy or counselling sessions.
  • Practice meditation and yoga to lower stress and anxiety.
  • Follow a regular sleep pattern.
  • Avoid smoking and alcohol consumption.
  • Learn about your condition, understand the risk factors and follow the doctor’s treatment plan.

Have a query?

How Soon It Starts Working

  • The time required for Sulpress Injection to start to work: The time required for Sulpress Injection to show its action is unknown.
  • The time for which the effects of Sulpress Injection last: The effect of Sulpress Injection lasts for 12 hours.

What if you forget to take Sulpress Injection

As this medicine is administered in a hospital by your healthcare professional, the chances of missing a dose are less. However, if you have any concerns, contact your doctor.

Storage

• Store in a cool and dry place away from sunlight.• Keep Sulpress Injection out of reach and sight of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Do not take Sulpress Injection if you are allergic to any of its ingredients or if you have tumours of the adrenal or pituitary glands, mania, epilepsy, breast cancer, or porphyria (a blood disorder).
  • Inform your doctor if you have/had stomach or intestinal bleeding, blockages or perforations, cerebrovascular problems, or any heart, kidney, or liver problems.
  • Sulpress Injection is not recommended during pregnancy and breastfeeding.
  • Sulpress Injection may cause drowsiness; therefore, be careful when driving or operating machinery until you know how it affects you.

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Drug-Drug Interactions: Sulpress Injection may interact with certain medicines, potentially increasing side effects or altering its effects. Inform your doctor if you are taking any of the following:

  • Central nervous system depressants (Alcohol, Codeine)
    Potential effect: May increase the risk of side effects like dizziness, drowsiness, or sedation.
  • Mood-stabilising agents (Lithium)
    Potential effect: May increase the risk of movement-related problems like tremors or stiffness.
  • Drugs used for high blood pressure (Metoprolol)
    Potential effect: May lower your blood pressure and cause increased dizziness, lightheadedness, or fainting.
  • Drugs used for a slow heart rate (Atropine)
    Potential effect: May slow down your gut movement, reducing the digestive benefits of Levosulpiride.
  • Antiparkinsonian drugs (Levodopa)
    Potential effect: May reduce the effectiveness of both medications.
  • Drugs used for heart rhythm disorders (Amiodarone, Quinidine)
    Potential effect: May increase the risk of QT prolongation and irregular heart rhythm.

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Sulpress Injection should be used with caution or avoided in people with:

  • Pheochromocytoma (tumour of the adrenal glands)
  • Prolactinoma (tumour of the pituitary gland)
  • Mania (a state of intense, irritable mood)
  • Epilepsy (seizures/fits)
  • Breast cancer
  • Porphyria (a blood disorder)

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Habit Forming

No

Therapeutic Class

[ANTIPSYCHOTICS, GASTROPROKINETIC AGENTS]

FAQs

Sulpress Injection is used to treat gastrointestinal problems such as dyspepsia (indigestion), diabetic gastroparesis (delayed stomach emptying caused by diabetes-related nerve damage), gastroesophageal reflux disease (GERD), irritable bowel syndrome (IBS), nausea, and vomiting when oral therapy is not advisable/feasible. Additionally, it may also be used to treat schizophrenia, psychosis, depression, anxiety, and Tourette's syndrome (repeated, uncontrollable movements or sounds).

Sulpress Injection contains Levosulpiride, which enhances the contractions in the gut and improves stomach emptying. This improves food movement through the gut, thereby treating disorders related to the stomach and intestines. Additionally, Sulpress Injection works by blocking dopamine activity in the brain, thereby improving mood, behaviour, and thoughts in psychotic disorders.

Sulpress Injection may cause weight gain. Maintain a proper weight by eating healthy food and regular exercise. Consult your doctor if you have any concerns.

Constipation could be a side effect of Sulpress Injection. However, it is not necessary for everyone taking Sulpress Injection to experience this side effect. If the condition persists or worsens, consult your doctor.

Sulpress Injection facilitates the emptying of food from the stomach, thereby treating diabetic gastroparesis, a diabetes-related condition that causes food to remain in the stomach for prolonged periods.

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Country of origin

India
Other Info - SU16315
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