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  3. Supacef 250 mg Injection 1's

Prescription drug
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Supacef 250 mg Injection 1's, Pack of 1 Injection
Supacef 250 mg Injection 1's, Pack of 1 Injection
Supacef 250 mg Injection 1's, Pack of 1 Injection
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy

Supacef 250 mg Injection is an antibiotic used in treating bacterial infections. It contains Cefuroxime, which stops the growth of bacteria. This medicine may cause side effects such as diarrhoea, nausea, vomiting, pain, and swelling at the site of injection. Let your doctor know if you are pregnant, breastfeeding, taking any other medicines or have pre-existing medical conditions.

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Composition :

CEFUROXIME-250MG

Manufacturer/Marketer :

GlaxoSmithKline Pharmaceuticals Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Supacef 250 mg Injection

Supacef 250 mg Injection belongs to the class of cephalosporin antibiotics indicated to treat a wide range of bacterial infections, including lower respiratory tract infections, urinary tract infections, skin and skin structure infections, septicemia (blood infection), meningitis (infection of brain and spinal cord), gonorrhoea (sexually transmitted infections), and bone and joint infections. Supacef 250 mg Injection is also used to prevent infections during surgery.

Supacef 250 mg Injection contains Cefuroxime, a broad-spectrum antibiotic, which works by blocking the activity of an enzyme that makes peptidoglycan (a vital component of the bacterial cell wall). This prevents the formation of bacterial cell covering, thereby killing the bacteria and treating bacterial infection.

In some cases, Supacef 250 mg Injection may cause side effects such as diarrhoea, nausea, vomiting, pain, and swelling at the site of injection. Most of these side effects do not require medical attention and resolve over time. However, if the side effects persist or worsen, consult your doctor.

Inform your doctor if you are allergic to any of the components in Supacef 250 mg Injection. Let your doctor know about your medical condition and the medications you are taking to avoid potential interactions. Consult your doctor if you are pregnant, breastfeeding, suspect you are pregnant or plan to have a baby.

Uses of Supacef 250 mg Injection

Supacef 250 mg Injection is a broad-spectrum cephalosporin antibiotic used to treat a variety of bacterial infections. The detailed uses of Supacef 250 mg Injection are as follows:

  • Respiratory tract infections: Supacef 250 mg Injection helps in the treatment of pulmonary infections caused by bacteria such as Streptococcus pneumoniae, Haemophilus influenzae, and Klebsiella spp.
  • Urinary tract infections (UTIs): Supacef 250 mg Injection effectively treats urinary tract infections caused by bacteria such as Escherichia coli and Klebsiella spp.
  • Treatment of skin and soft tissue infections: Supacef 250 mg Injection is used to treat cellulitis or wound infections caused by susceptible bacteria like Staphylococcus aureus and Streptococcus pyogenes.
  • Septicemia: Supacef 250 mg Injection is used to treat blood infections caused by bacteria like E. coli, Streptococcus pneumoniae, and Haemophilus influenzae.
  • Bacterial meningitis: Supacef 250 mg Injection is prescribed to manage infections of the brain and spinal cord lining caused by organisms like Neisseria meningitidis and Streptococcus pneumoniae.
  • Gonorrhea: Supacef 250 mg Injection is used to manage both uncomplicated and more widespread forms of gonococcal infections caused by Neisseria gonorrhoeae.
  • Bone and joint infections: Supacef 250 mg Injection is indicated for infections affecting bones and joints, including those caused by Staphylococcus aureus.

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Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safe and effective use.
  • Supacef 250 mg Injection will be administered by the doctor or healthcare professional.
  • Do not self-administer.

Medicinal Benefits

  • Supacef 250 mg Injection is a broad-spectrum antibiotic that is used to treat a wide range of bacterial infections.
  • It is commonly prescribed for respiratory tract infections, ear infections, skin and soft tissue infections, genitourinary tract infections, and bone infections.
  • In addition to treating existing infections, Supacef 250 mg Injection is also used to prevent infections that may occur after surgical procedures.
  • It is effective in the early treatment of Lyme disease, caused by the bacterium Borrelia burgdorferi, in adults and children over the age of 12 years.
  • Supacef 250 mg Injection works by inhibiting the activity of an enzyme responsible for producing peptidoglycan, a vital component of the bacterial cell wall. By blocking the formation of this protective cell wall, Supacef 250 mg Injection causes the bacterial cells to break down and die, thereby eliminating the infection from the body.

How Supacef 250 mg Injection Works

Supacef 250 mg Injection is a broad-spectrum antibiotic that acts against a wide range of bacteria. It works by blocking the activity of an enzyme that makes peptidoglycan (a vital component of the bacterial cell wall). This prevents the formation of bacterial cell covering, thereby killing the bacteria and treating bacterial infection.

Storage

• Store in a cool and dry place away from sunlight.• Keep out of sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Supacef 250 mg Injection
Managing Medication-Triggered Thrombophlebitis (Inflammation of a vein): A Step-by-Step Guide:
  • If you have symptoms such as pain, swelling, redness, or warmth in your veins after taking medication, contact your doctor right once. Share information about your symptoms, medication regimen, and medical history.
  • Your doctor will then assess your medication regimen to determine if it's contributing to the thrombophlebitis. This assessment will help identify the best course of action to manage your condition and prevent further complications.
  • Your doctor may suggest certain diet and lifestyle changes to help manage your condition. This may include increasing your intake of foods rich in omega-3 fatty acids, staying hydrated, exercising regularly, and maintaining a healthy weight. Your doctor may also advise medications to reduce inflammation, prevent blood clots, or manage pain if necessary.
  • If your condition does not improve or persists, consult your doctor and report your condition. Your doctor will assess your progress, adjust your treatment plan if necessary, and provide appropriate advice to ensure the best possible outcome.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the few steps for dealing with itching caused by drug use:
  • Report the itching to your doctor immediately; they may need to change your medication or dosage.
  • Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
  • Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
  • Try not to scratch, as this can worsen the itching and irritate your skin.
  • If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
  • Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.
  • Avoid trigger foods that can cause allergic reactions, such as nuts, shellfish, or dairy products.
  • Keep a food diary to track potential food allergens.
  • Include omega-3 rich foods like salmon and walnuts to reduce inflammation.
  • Wear loose, comfortable clothing made from soft fabrics like cotton.
  • Apply cool compresses or take cool baths to reduce itching.
  • Use gentle soaps and avoid harsh skin products.
  • Reduce stress through relaxation techniques like meditation or deep breathing.
  • If you experience or encounter any severe allergic reaction, stop using medication and consult the doctor right away.
  • Tell your doctor about the allergic reaction, including the medication taken and any symptoms experienced.
  • Your doctor will evaluate the severity of the reaction and determine the best course of action.
  • To ensure a full recovery, follow your doctor's advice, attend scheduled follow-up appointments, and undergo recommended tests to monitor progress and adjust treatment as needed.
  • Notify your doctor about the fever caused by medication and follow their guidance to adjust or stop the medication.
  • Drink plenty of fluids, like water or electrolyte-rich beverages, and eat healthy food.
  • Get plenty of rest to help your body recover or adjust to the medication.
  • Track your temperature and report changes to your doctor.
  • Use fever-reducing medications like acetaminophen if recommended.

What if I have taken an overdose of Supacef 250 mg Injection

Supacef 250 mg Injection is administered by a healthcare professional in a hospital setting. Hence, the chances of overdose are less. Overdose can cause black, tarry stools, chest pain, fever, shortness of breath, sore throat, sores, ulcers, white spots on lips or mouth, and unusual tiredness or weakness. Your doctor may initiate necessary treatment if an overdose is suspected.

Drug Warnings

  • Do not take Supacef 250 mg Injection if you are allergic to any of the contents.
  • Consult your doctor if you are pregnant or breastfeeding.
  • Inform your doctor if you have kidney or liver problems.
  • Supacef 250 mg Injection may cause Clostridioides difficile-associated diarrhoea (CDAD). If you experience severe, persistent diarrhoea, or if you find blood or mucus in your stools, consult your doctor immediately.
  • Let your doctor know about your medical condition and the medications you are taking to avoid potential interactions.

Drug-Drug Interactions

verifiedApollotooltip
CefuroximeBCG vaccine
Severe
CefuroximeDalteparin
Severe

Drug-Drug Interactions

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CefuroximeBCG vaccine
Severe
How does the drug interact with Supacef 250 mg Injection:
Co-administration of Supacef 250 mg Injection may reduce the anti-tumor activity of BCG in the bladder.

How to manage the interaction:
Talk to your doctor before receiving BCG if you are currently being treated with Supacef 250 mg Injection. To ensure adequate response to your treatment, you should not receive BCG until after you complete your antibiotic therapy. Do not discontinue the medication without consulting a doctor.
CefuroximeDalteparin
Severe
How does the drug interact with Supacef 250 mg Injection:
Co-administration of Dalteparin and Supacef 250 mg Injection can increase the blood levels and effects of Dlateparin.

How to manage the interaction:
Taking Supacef 250 mg Injection with Dalteparin together can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
CefuroximeLepirudin
Severe
How does the drug interact with Supacef 250 mg Injection:
The therapeutic efficacy of Lepirudin can be decreased when used in combination with Supacef 250 mg Injection.

How to manage the interaction:
Although taking Supacef 250 mg Injection and Lepirudin together can evidently cause an interaction, it can be taken if your doctor has suggested it. Do not stop using any medications without a doctor's advice.
CefuroximeRanitidine
Moderate
How does the drug interact with Supacef 250 mg Injection:
Taking these medications together might make it harder for your body to absorb atazanavir, which could make it less effective.

How to manage the interaction:
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Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • After completing the course of Supacef 250 mg Injection, probiotics should be taken to restore healthy bacteria in the intestine that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut, and kimchi can help restore the intestine's good bacteria.
  • Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria, which helps stimulate their growth.
  • Avoid taking too much calcium-enriched foods and drinks, as it might affect the working of Supacef 250 mg Injection.
  • Avoid intake of alcoholic beverages with Supacef 250 mg Injection as it can make you dehydrated and affect your sleep. This can make it harder for your body to aid Supacef 250 mg Injection in fighting off infections.

Habit Forming

No

Therapeutic Class

ANTI- BACTERIALS

Supacef 250 mg Injection Substitute

Substitutes safety advice
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Alcohol

Caution

It is not known if alcohol affects Supacef 250 mg Injection. However, as a precautionary measure, it is advisable not to take or limit alcohol.

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Pregnancy

Caution

Please consult the doctor as there are no adequate and well-controlled studies on pregnant women. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Please consult your doctor. Your doctor will weigh the benefits and potential risks before prescribing Supacef 250 mg Injection.

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Driving

Caution

Supacef 250 mg Injection may cause dizziness. Drive or operate machinery only if you are alert.

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Liver

Caution

Limited information is available regarding the use of Supacef 250 mg Injection in patients suffering from liver impairment. Please consult your doctor. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Dose adjustment may be needed. Please consult your doctor if you have kidney problems.

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Children

Safe if prescribed

Supacef 250 mg Injection can be given safely to children provided a child specialist has prescribed the dose.

FAQs

Supacef 250 mg Injection belongs to the class of cephalosporin antibiotics indicated to treat a wide range of bacterial infections, including lower respiratory tract infections, urinary tract infections, skin and skin structure infections, septicemia (blood infection), meningitis (infection of brain and spinal cord), gonorrhoea (sexually transmitted infections), and bone and joint infections. Supacef 250 mg Injection is also used to prevent infections during surgery.

Supacef 250 mg Injection works by blocking the activity of an enzyme that makes peptidoglycan (a vital component of the bacterial cell wall). This prevents the formation of bacterial cell covering, thereby killing the bacteria and treating bacterial infection.

After taking an antibiotic, you may need to wait up to three hours before eating or drinking any dairy products, including milk, butter, yoghurt, and cheese. Grapefruit juice and dietary supplements containing minerals like calcium may also affect the effectiveness of antibiotics.

Supacef 250 mg Injection is used to treat bacterial infections and does not treat viral infections such as cough, flu or cold.

Supacef 250 mg Injection may interact with birth control pills and lower their efficiency. Inform your doctor if you use any birth control pills.

Supacef 250 mg Injection may cause Clostridioides difficile-associated diarrhoea (CDAD). If you experience severe, persistent diarrhoea, or if you find blood or mucus in your stools, consult your doctor immediately. Do not take anti-diarrhoeal medicine on your own.

Country of origin

India

Manufacturer/Marketer address

Dr. Annie Besant Road, Mumbai - 400 030
Other Info - SUP0032

Disclaimer

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Santoshini Reddy GDoctor badge

Reviewed By

Santoshini Reddy G

M Pharmacy

Last Updated

Aug 1, 2025 | 2:48 PM IST

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Reference

  1. https://www.ncbi.nlm.nih.gov/books/NBK501464/
  2. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2014391/#:~:text=According%20to%20the%20manufacturer%20there,especially%20during%20the%20first%20trimester.
  3. https://cdscoonline.gov.in/CDSCO/Drugs
  4. https://www.medicines.org.uk/emc/files/pil.149.pdf
  5. https://www.medicines.org.uk/emc/product/149/smpc

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