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compositionComposition:MENOTROPHIN-75IU
prescription
Prescription Medicine
info
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Supergraf-75 IU Combipack Injection 1's belongs to the class of hormones used in the treatment of female infertility, male infertility and male hypogonadism. This medicine works by increasing male hormone production (testosterone), which helps treat low sperm count and delayed puberty and helps induce ovulation (egg production) in a woman. Common side effects include injection site pain, fatigue, headache, irritation, depression, and restlessness.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
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More about the Product

Composition :

MENOTROPHIN-75IU

Manufacturer/Marketer :

Gufic Biosciences Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About Supergraf-75 IU Combipack Injection 1's

Supergraf-75 IU Combipack Injection 1's is a prescription injection used to treat infertility in both women and men. It helps stimulate the ovaries in women who are having trouble ovulating or undergoing fertility treatments, and it supports sperm production in men with certain hormone deficiencies. This medication provides the essential hormones needed to promote reproductive health and aid conception.

You will typically inject Supergraf-75 IU Combipack Injection 1's daily or as scheduled by your fertility specialist, and it must be used consistently at the same time each day for the best results. Since it is an injection, it can be taken with or without food. Eating a nutrient-rich diet, managing stress, and maintaining a healthy weight can significantly support your body and improve your results during this treatment.

While using Supergraf-75 IU Combipack Injection 1's, you may experience mild side effects like pain or redness at the injection site, headaches, or mild bloating. However, it is vital to contact your doctor immediately if you experience severe pelvic pain, extreme bloating, rapid weight gain, or breathing difficulties, as these could be signs of a serious condition affecting the ovaries.

Before starting this treatment, talk to your doctor if you have thyroid issues, adrenal gland disorders, or a history of blood clots. Do not take this if you have undiagnosed vaginal bleeding, ovarian cysts not caused by polycystic ovary syndrome (PCOS), or cancers of the breast, uterus, or ovaries. 

Avoid smoking and drinking alcohol while taking Supergraf-75 IU Combipack Injection 1's, as they can decrease your chances of a successful pregnancy and affect overall reproductive health. Since this medication is specifically used to help achieve pregnancy, it is usually discontinued once pregnancy is confirmed. It is also generally not recommended during breastfeeding unless specifically advised by your healthcare provider. 

Uses of Supergraf-75 IU Combipack Injection 1's

Supergraf-75 IU Combipack Injection 1's is used in the treatment of female infertility and male infertility. The detailed uses of Supergraf-75 IU Combipack Injection 1's are as follows:

  • Female Infertility: Supergraf-75 IU Combipack Injection 1's helps stimulate the growth and maturation of eggs in women who do not ovulate regularly or are undergoing assisted reproductive techniques such as in vitro fertilization (IVF).
  • Male Infertility: It helps stimulate sperm production in men with certain hormone deficiencies that affect fertility.

Key Benefits

Supergraf-75 IU Combipack Injection 1's helps support fertility by providing hormones that play an important role in normal reproductive function. It is used under specialist supervision to help address certain causes of infertility in both women and men.

Benefits may include:

• Helps stimulate the development of healthy eggs in women with ovulation or fertility problems.
• Supports fertility treatments such as in-vitro fertilization (IVF) by promoting the growth of multiple mature follicles.
• Helps restore or support normal reproductive function when hormone levels are insufficient.
• May improve sperm production and reproductive health in selected men with hormone-related infertility.
• Supports family planning goals by helping improve the chances of conception.
• Provides targeted hormonal support as part of a comprehensive fertility treatment plan under medical supervision.

Side effects of Supergraf-75 IU Combipack Injection
  • Eat smaller, more frequent meals.
  • Eat slowly and chew your food thoroughly to help digestion.
  • Eat fiber-rich foods such as fruits, whole grains, and vegetables to promote regular bowel movements.
  • Avoid gas-producing foods like cabbage, beans, broccoli and carbonated drinks.
  • Drink lots of water throughout the day to prevent dehydration and aid digestion.
  • Do regular exercise to enhance digestion and reduce bloating.
  • If you have discomfort, illness, or unease after taking medication, seek medical attention.
  • Your treatment plan may be modified, including adjusting the dosage, substituting with an alternative medication, or discontinuing the medication. Additionally, certain lifestyle changes may be recommended to help manage symptoms.
  • To manage discomfort, follow your doctor's advice, like getting plenty of rest, or staying hydrated, and practising stress-reducing techniques.
  • Track your symptoms regularly and report any changes or concerns to your healthcare provider to manage the discomfort effectively.

Directions for Use

  • Follow your doctor's instructions regarding dosage and timing of Supergraf-75 IU Combipack Injection 1's for better results.
  • Supergraf-75 IU Combipack Injection 1's will be administered by a healthcare professional.
  • Do not self-administer.

How Supergraf-75 IU Combipack Injection 1's Works

Supergraf-75 IU Combipack Injection 1's contains Follicle-Stimulating Hormone (FSH) and Luteinizing Hormone (LH). Follicle-Stimulating Hormone (FSH): It helps stimulate the growth and development of ovarian follicles that contain eggs. In men, it supports the production and development of healthy sperm. Luteinizing Hormone (LH): It supports the maturation of eggs and plays an important role in normal reproductive function. In men, it helps stimulate the production of testosterone, which is essential for healthy sperm production.
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Alcohol

Unsafe

Alcohol consumption may worsen your condition and increase the risk of side effects.

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Pregnancy

Unsafe

Supergraf-75 IU Combipack Injection 1's is a category C drug. It should not be given to pregnant women as Supergraf-75 IU Combipack Injection 1's may cause harm to the unborn baby.

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Breast Feeding

Caution

It is not known that Supergraf-75 IU Combipack Injection 1's may pass into breast milk. Therefore, it should be used with caution in breastfeeding mothers.

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Driving

Caution

Supergraf-75 IU Combipack Injection 1's may affect your ability to drive, so do not drive or operate heavy machinery after taking Supergraf-75 IU Combipack Injection 1's until your vision gets normal.

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Liver

Caution

Supergraf-75 IU Combipack Injection 1's should be used with extreme caution in patients with liver disease as the liver metabolizes this medicine. Dose adjustments may be necessary.

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Kidney

Caution

Supergraf-75 IU Combipack Injection 1's can be used in patients with kidney diseases if clinically required.

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Children

Unsafe

Supergraf-75 IU Combipack Injection 1's is not recommended for use in children.

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Heart

Caution

Limited information was available regarding the use of Supergraf-75 IU Combipack Injection 1's in patients with heart problems. Please consult your doctor.

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Geriatrics

Not applicable

Supergraf-75 IU Combipack Injection 1's is not indicated for use in elderly patients, as it offers no relevant clinical benefit in this age group.

What if I have taken an overdose of Supergraf-75 IU Combipack Injection 1's

If you inject more Supergraf-75 IU Combipack Injection 1's than prescribed, seek immediate medical attention or contact a poison control center. An overdose can increase the risk of serious complications, such as severe ovarian overstimulation.

Diet & Lifestyle Advise

  • Eat a Mediterranean-style diet: Focus on whole grains, healthy fats (like olive oil and avocados), lean proteins, and plenty of leafy greens to support egg and sperm quality.
  • Stay hydrated: Drink plenty of water daily, especially during treatment, as proper hydration supports cell function and helps manage mild bloating.
  • Avoid alcohol and limit caffeine: Both substances can negatively affect hormone levels and lower the success rates of fertility treatments.
  • Manage stress levels: Engage in gentle, low-impact activities like yoga, meditation, or walking. Avoid strenuous high-intensity workouts unless cleared by your fertility specialist.
  • Maintain a consistent sleep schedule: Aim for 7 to 8 hours of quality sleep each night to help regulate your body's natural hormone production.
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How Soon It Starts Working

The time required for Supergraf-75 IU Combipack Injection 1's to start to work: The time required for Supergraf-75 IU Combipack Injection 1's to show its action is unknown. The time for which the effects of Supergraf-75 IU Combipack Injection 1's last: The duration of action for Supergraf-75 IU Combipack Injection 1's is clinically unknown.

What if you forget to take Supergraf-75 IU Combipack Injection 1's

If you miss a dose of Supergraf-75 IU Combipack Injection 1's, do not inject a double dose to make up for the missed one. Contact your doctor or fertility clinic immediately for instructions on when to take your next injection.

Storage

•Store Supergraf-75 IU Combipack Injection 1's according to the package instructions. •Storage recommendations vary by brand and formulation.
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Keep Refrigerated. Do not freeze.

Drug Warnings

  • Inspect the solution before use: Do not use Supergraf-75 IU Combipack Injection 1's if the liquid contains particles, appears cloudy, or has changed color.
  • Rotate injection sites: Use a different area of your abdomen or thigh for each injection to help reduce skin irritation, soreness, and scarring.
  • Attend all monitoring appointments: Keep all scheduled blood tests and vaginal ultrasound appointments so your doctor can monitor your response to treatment and help prevent complications.
  • Watch for signs of OHSS: Monitor your weight regularly and contact your healthcare team immediately if you develop sudden weight gain, severe bloating, or abdominal pain, as these may be signs of Ovarian Hyperstimulation Syndrome (OHSS).
  • Do not share injection equipment: Never share needles, syringes, or vials with another person, as this may lead to serious infections or transmission of blood-borne diseases.
  • Understand the treatment process: Supergraf-75 IU Combipack Injection 1's is one part of fertility treatment and may be followed by additional steps such as regular ultrasound and blood test monitoring, a trigger injection to complete egg maturation, egg retrieval for IVF procedures, insemination, or embryo transfer.
  • Use with caution in certain patients: Do not use Supergraf-75 IU Combipack Injection 1's if you have unexplained vaginal bleeding, ovarian cysts unrelated to PCOS, cancer of the breast, uterus, ovaries, pituitary gland, or hypothalamus, uncontrolled thyroid or adrenal gland disorders, a known allergy to Supergraf-75 IU Combipack Injection 1's or any of its ingredients, or if you are already pregnant.
  • Additional monitoring information: Close monitoring is an important part of Supergraf-75 IU Combipack Injection 1's treatment. Your fertility specialist will typically perform ultrasound scans to assess developing follicles (fluid-filled sacs in the ovaries that contain eggs) and blood tests to measure hormone levels, including estradiol.

Drug-Drug Interactions

verifiedApollotooltip
  • Other fertility medicines (e.g., clomiphene): Taking these medicines alongside Supergraf-75 IU Combipack Injection 1's may increase ovarian stimulation and raise the risk of ovarian hyperstimulation syndrome (OHSS).
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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  • No specific food interactions have been established with Supergraf-75 IU Combipack Injection 1's. Maintaining a balanced, nutrient-rich diet during fertility treatment may help support overall health and treatment outcomes.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[SEX HORMONE]

FAQs

Yes. Like most injections, Supergraf-75 IU Combipack Injection 1's may cause mild pain, tenderness, redness, bruising, warmth, or numbness at the injection site. These reactions are usually temporary. Rotating injection sites, allowing the medication to reach room temperature before injection, and applying a cold compress may help reduce discomfort. If the pain is severe, persists, or is accompanied by swelling, pus, or signs of infection, contact your doctor immediately.
Supergraf-75 IU Combipack Injection 1's can rarely cause breast pain and swelling of breasts. Inform your doctor if you feel any discomfort or side effect of Supergraf-75 IU Combipack Injection 1's and follow the advice given by your doctor.
In women, Supergraf-75 IU Combipack Injection 1's stimulates the ovaries to promote follicle development and induce ovulation, helping women who have difficulty producing eggs become pregnant. In men, it stimulates the testes to produce testosterone and healthy sperm, helping improve sperm count and fertility in men with certain hormonal deficiencies.
Contact your doctor immediately if you experience severe pelvic or abdominal pain, severe nausea or vomiting, diarrhoea, trouble breathing, rapid weight gain, reduced or no urination, severe bloating, or swelling while using Supergraf-75 IU Combipack Injection 1's. These symptoms may indicate Ovarian Hyperstimulation Syndrome (OHSS), a serious complication requiring urgent medical attention.
Supergraf-75 IU Combipack Injection 1's contains Menotrophin, which belongs to the group of medications known as sex hormones. It is used to treat infertility in women who are not ovulating (not producing eggs properly), male infertility, and male hypogonadism (a condition where the body does not produce enough of a certain hormone, leading to problems with sexual function).
Yes, Supergraf-75 IU Combipack Injection 1's is often used in the treatment of male infertility (It is a lack of male ability to cause pregnancy in a fertile female even after exposed intercourse. It normally happens because of sperm that are irregular or have problems with ejaculation) and Male hypogonadism (a disorder in which the body does not make enough of the hormone that plays a key role in male sex development and growth during puberty or enough sperm or both).
Supergraf-75 IU Combipack Injection 1's is typically administered through injection, either subcutaneously (SC) or intramuscularly (IM). The treatment dose and duration may vary and are usually determined by a healthcare provider based on the individual's response. Please do not self-administer it.
If you miss a dose of Supergraf-75 IU Combipack Injection 1's, take it as soon as you remember unless it is almost time for your next dose. Do not double the dose to make up for a missed one.
The common side effects of Supergraf-75 IU Combipack Injection 1's include injection site pain, fatigue, headache, irritation, depression, and restlessness. Most of these side effects of Supergraf-75 IU Combipack Injection 1's do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
Yes, many patients inject Supergraf-75 IU Combipack Injection 1's at home after receiving proper training from their healthcare provider. Do not attempt to inject it until you feel completely confident in the preparation and injection process. Consult your doctor if you have any questions or concerns about self-injection.
Yes, because Supergraf-75 IU Combipack Injection 1's stimulates the ovaries to produce multiple eggs, it significantly increases the likelihood of multiple pregnancies (like twins or triplets). Your doctor will monitor your cycle closely to manage this risk.
Yes, but you must plan ahead to ensure the medication is stored at the correct temperature during travel. Use a cooler bag with ice packs if refrigeration is required, and carry a doctor's letter explaining your need for needles and syringes.
No, Supergraf-75 IU Combipack Injection 1's is only intended to help you become pregnant. Once pregnancy is confirmed, you must stop using it immediately, as it is not safe for use during pregnancy. Inform your doctor to confirm when you should stop the injections.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

37,1st Floor, Kamala Bhavan II, Swami Nityanand Road, Andheri (East), Mumbai - 400 069. (INDIA)
Other Info - SUP0730
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