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Supral 10mg Tablet is used to treat schizophrenia and bipolar disorder. It helps improve mood, thinking, and behaviour. It balances brain chemicals, reducing symptoms such as mood swings, agitation, and disturbed thoughts.

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Written By Dr. Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

OLANZAPINE-10MG

Manufacturer/Marketer :

A N Pharmacia Laboratories Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Supral 10mg Tablet

Supral 10mg Tablet is a prescription medicine used to treat schizophrenia and manic or depressive episodes associated with bipolar disorder. It helps restore the balance of certain natural chemicals in the brain to improve thinking, mood, and behaviours. Doctors may prescribe it alone or alongside other treatments to help manage these long-term mental health conditions.

To get the most benefit, you should take Supral 10mg Tablet consistently every day at the same time, exactly as prescribed by your doctor. You can take this medicine with or without food, making it easy to incorporate into your daily routine. Combining this treatment with regular sleep habits, a balanced diet, and routine physical activity can significantly support your long-term health outcomes.

While taking Supral 10mg Tablet , you may experience common side effects like sleepiness, dry mouth, or increased appetite. Most of these are mild, but you should contact your doctor immediately if you experience serious side effects such as high fever, severe muscle stiffness, or unusual, uncontrolled movements of your face or tongue.

Before starting this medicine, tell your doctor if you have a history of diabetes, high cholesterol, liver damage, or heart problems. Do not take this if you are allergic to any of the ingredients in Supral 10mg Tablet , or if you are at risk for certain eye conditions like narrow-angle glaucoma.

Drinking alcohol while taking Supral 10mg Tablet can make you feel excessively sleepy and dizzy, so it is best avoided. Smoking can speed up how quickly your body clears this medicine, potentially making it less effective, so tell your doctor if you smoke or plan to quit. If you are pregnant, breastfeeding, or caring for an elderly patient with dementia, talk to your doctor or pharmacist before using this medicine, as special precautions are needed.
 

Uses of Supral 10mg Tablet

Supral 10mg Tablet is used to treat schizophrenia and manic or depressive episodes associated with bipolar disorder. The detailed uses of Supral 10mg Tablet are as follows:

  • Schizophrenia: Supral 10mg Tablet helps reduce symptoms like hearing voices, seeing things that are not there, or feeling unusually suspicious of others, helping you think more clearly and engage with daily life.
  • Bipolar Disorder (Manic Episodes): It works to control episodes of extreme excitement, overactivity, and irritability, bringing your mood back to a stable level.
  • Bipolar Depression: When used in combination with other prescribed medications, Supral 10mg Tablet helps relieve severe feelings of sadness, low energy, and worthlessness during depressive phases

Key Benefits

Supral 10mg Tablet helps manage symptoms of serious mental health conditions by improving mood stability, reducing psychotic symptoms, and supporting overall daily functioning. With regular use as prescribed, it helps improve emotional well-being and quality of life.

  • Stabilises Mood: This medicine helps reduce severe mood swings and emotional highs and lows, promoting greater emotional balance and stability.
  • Improves Thinking and Focus: By reducing hallucinations, disorganised thinking, and suspicious thoughts, this medicine helps improve concentration, mental clarity, and the ability to carry out daily tasks.
  • Supports Healthy Sleep: Regular use helps improve disturbed sleep patterns, promoting better rest and supporting emotional recovery and daytime energy.
  • Enhances Daily Functioning: By controlling symptoms, this medicine helps you participate more comfortably in work, school, social activities, and everyday responsibilities with greater confidence and independence.
     
Side effects of Supral 10mg Tablet
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Eat fatty fish rich in omega-3 fatty acids to reduce inflammation.
  • Add whole grains such as brown rice, quinoa, and whole wheat bread to your diet for a nutritional boost.
  • Add nuts and seeds like almonds, walnuts, chia seeds for anti-inflammatory benefits.
  • Eat dark leafy greens like spinach, kale, collard greens for antioxidants.
  • Include berries like blueberries, strawberries, raspberries for anti-inflammatory properties.
  • Rest and take a break from usual activities.
  • Apply ice for 15-20 minutes, 3 times a day to reduce pain and inflammation.
  • Use compression with a stretchable bandage or wrap to lessen swelling and provide support.
  • Avoid strenuous activities and rest the affected area.
  • Try light stretching with gentle exercises to maintain flexibility.
  • Consider OTC pain medications like ibuprofen or acetaminophen but consult a doctor before taking any medication.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.

Directions for Use

  • Supral 10mg Tablet can be taken with food to help reduce the risk of stomach upset.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow Supral 10mg Tablet as a whole with a glass of water.
  • Do not crush, break, or chew it.

How Supral 10mg Tablet Works

Supral 10mg Tablet contains olanzapine, which works by acting on specific chemical messengers in your brain, primarily dopamine and serotonin. These natural chemicals carry signals between brain cells and play a critical role in regulating your mood, thoughts, and behaviours. In conditions like schizophrenia and bipolar disorder, the balance of these chemicals is often disrupted. By gently blocking certain receptors for dopamine and serotonin, Supral 10mg Tablet helps restore a healthier chemical balance, which reduces hallucinations, calms overactive thinking, and stabilises your overall mood.
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Alcohol

Unsafe

It is advised to avoid alcohol consumption while taking Supral 10mg Tablet . Alcohol intake and Supral 10mg Tablet may cause increased dizziness and drowsiness. Please consult your doctor for more information.

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Pregnancy

Caution

Supral 10mg Tablet is a pregnancy category C drug. Using antipsychotic drugs during the third trimester of pregnancy can cause muscle problems in newborn babies. Please inform your doctor before taking Supral 10mg Tablet if you are pregnant or planning to conceive. Your doctor will weigh the potential risks and benefits before prescribing Supral 10mg Tablet .

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Breast Feeding

Unsafe

Supral 10mg Tablet is excreted into the breast milk; hence it is not recommended for a nursing mother. Inform your doctor before taking Supral 10mg Tablet if you are a breastfeeding mother.

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Driving

Unsafe

Supral 10mg Tablet may make you feel dizzy or drowsy. Do not drive if you are not mentally alert or experience any symptoms that affect your ability to drive or operate machinery.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please inform your doctor if you have a liver impairment or any concerns.

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Kidney

Caution

Please inform your doctor before using Supral 10mg Tablet if you suffer from severe kidney impairment. Your doctor may adjust the dose if necessary based on your condition.

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Children

Caution

Supral 10mg Tablet is not recommended in people below 12 years of age.

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Heart

Caution

Supral 10mg Tablet should be taken with caution in patients with heart problems. Please inform your doctor if you have any pre-existing heart problems before using Supral 10mg Tablet .

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Geriatrics

Caution

Supral 10mg Tablet should be given cautiously to elderly patients with dementia, as it may slightly increase the risk of death. Consult your physician if you have any concerns.

What if I have taken an overdose of Supral 10mg Tablet

If you take too much of Supral 10mg Tablet , seek immediate medical attention or call emergency services right away. Symptoms of an overdose may include extreme sleepiness, slurred speech, agitation, or a very fast heart rate.

Diet & Lifestyle Advise

  • Manage Your Weight: Supral 10mg Tablet can increase your appetite and lead to weight gain. Keep a food diary, practise portion control, and focus on nutrient-dense foods like vegetables, lean proteins, and whole grains.
  • Monitor Blood Sugar and Lipids: Since this medicine can affect how your body processes sugars and fats, schedule regular blood tests with your doctor to monitor your glucose and cholesterol levels.
  • Stay Hydrated: Drink plenty of water throughout the day to help manage dry mouth and reduce the risk of constipation.
  • Stand Up Slowly: To prevent dizziness or lightheadedness caused by a sudden drop in blood pressure, take your time when rising from a sitting or lying position.
  • Limit Sugary Drinks: Avoid high-calorie sodas and juices, which can contribute to weight gain and blood sugar spikes while taking this medication.
     
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How Soon It Starts Working

  • The time required for Supral 10mg Tablet to start to work: Supral 10mg Tablet ideally shows its action within 5 to 8 hours after administration.
  • The time for which the effects of Supral 10mg Tablet last: The effect of Supral 10mg Tablet lasts for 21 to 54 hours.

What if you forget to take Supral 10mg Tablet

Take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one and return to your regular schedule. Do not take two doses at the same time to make up for a missed one.

Storage

• Store Supral 10mg Tablet tablets at room temperature, ideally between 20°C and 25°C (68°F to 77°F).

Drug Warnings

  • Avoid driving, riding a bicycle, or operating machinery until you know how Supral 10mg Tablet affects you, as it can cause significant drowsiness and slow your reaction times.
  • Avoid getting overheated or dehydrated. This medicine can make it harder for your body to cool down, especially during hot weather or intense physical exercise.
  • Do not stop taking Supral 10mg Tablet abruptly. Stopping suddenly can trigger withdrawal symptoms or cause your mental health condition to worsen. Your doctor will help you by gradually decreasing your dose if you need to stop.
  • Keep all laboratory appointments. Your doctor will need to run regular blood tests to check your liver function, blood sugar, and lipid levels.
  • Be cautious when consuming caffeine, as high amounts of coffee, tea, or energy drinks can change the levels of this medicine in your body.
     

Drug-Drug Interactions

verifiedApollotooltip
  • Blood pressure medications: Combining these with Supral 10mg Tablet may cause your blood pressure to drop too low, leading to dizziness or fainting.
  • Sedatives and sleeping pills: Taking these alongside Supral 10mg Tablet can cause severe drowsiness, slowed breathing, and coordination problems.
  • Parkinson's disease medications: Supral 10mg Tablet may decrease the effectiveness of these medications, potentially worsening movement symptoms.

 

OlanzapinePotassium citrate
Critical

Drug-Drug Interactions

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OlanzapinePotassium citrate
Critical
How does the drug interact with Supral 10mg Tablet:
Taking Supral 10mg Tablet with Potassium citrate can increase the irritant effects of potassium on your stomach and upper intestine.

How to manage the interaction:
Co-administration of Supral 10mg Tablet and Potassium citrate is not recommended as it leads to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like severe abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, and/or black, tarry stools, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Supral 10mg Tablet:
When Ropinirole is taken with Supral 10mg Tablet, it may reduce the effectiveness of ropinirole.

How to manage the interaction:
Taking Ropinirole with Supral 10mg Tablet is not recommended as it can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as drowsiness, low blood pressure, dizziness, and lightheadedness. Do not stop using any medications without consulting doctor.
How does the drug interact with Supral 10mg Tablet:
Taking Supral 10mg Tablet with Pramipexole can increase the risk and severity of side effects and reduce the effectiveness of Pramipexole.

How to manage the interaction:
Co-administration of Supral 10mg Tablet and Pramipexole is not recommended as it leads to an interaction, it can be taken if advised by a doctor. If you experience any symptoms such as drowsiness, dizziness, and lightheadedness, contact a doctor immediately. Avoid driving or operating dangerous machinery, and be careful while getting up from a sitting or lying position. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Supral 10mg Tablet:
Taking Supral 10mg Tablet with Potassium chloride can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Co-administration of Supral 10mg Tablet and Potassium chloride is not recommended as it leads to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like severe abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, and/or black, tarry stools, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Supral 10mg Tablet:
Co-administration of Supral 10mg Tablet with tramadol can increase the risk of irregular heart rhythms.

How to manage the interaction:
Taking Supral 10mg Tablet with tramadol together can possibly result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not discontinue any medications without consulting a doctor.
OlanzapineSufentanil
Severe
How does the drug interact with Supral 10mg Tablet:
Combining Supral 10mg Tablet with Sufentanil can cause central nervous system depression such as Supral 10mg Tablet can lead to serious side effects including respiratory distress, intestinal obstruction, fecal impaction.

How to manage the interaction:
Although taking Supral 10mg Tablet and Sufentanil together can lead to an interaction, it can be taken if your doctor has suggested it. If you experience any symptoms like feeling tired, having trouble breathing, feeling dizzy or drowsy, difficulty focusing, taking pain or cough medications, constipation, blockage in your intestines, difficulty passing stool, hard or dry stool, less frequent bowel movements, stomach problems, feeling sick, feeling bloated, having stomach pain, or swelling contact the doctor immediately. you should avoid driving or operating hazardous machinery until you know how they affect you and do not discontinue any medications without consulting your doctor.
How does the drug interact with Supral 10mg Tablet:
Taking diazepam together with Supral 10mg Tablet can cause low blood pressure, weak pulse, shallow breathing, muscle weakness, drowsiness, dizziness and slurred speech.

How to manage the interaction:
Combining Supral 10mg Tablet and Diazepam can lead to an interaction, it can be taken if your doctor has suggested it. If you experience any symptoms consult the doctor immediately. Avoid activities requiring mental alertness until you know how these medications will affect you. Do not stop using any medications without first talking to your doctor.
OlanzapineEsketamine
Severe
How does the drug interact with Supral 10mg Tablet:
Using esketamine together with Supral 10mg Tablet can increase side effects such as drowsiness, confusion, difficulty concentrating, and impairment in thinking, judgment, reaction speed, and motor coordination.

How to manage the interaction:
Co-administration of esketamine and Supral 10mg Tablet can lead to an interaction, it can be taken if advised by your doctor. If you experience any symptoms, contact your doctor immediately. Avoid driving or operating hazardous machinery until the next day after a restful sleep and do not discontinue any medications without first consulting your doctor.
OlanzapineAlfentanil
Severe
How does the drug interact with Supral 10mg Tablet:
Combining Supral 10mg Tablet with Alfentanil can cause central nervous system depression such as Supral 10mg Tablet can lead to serious side effects including respiratory distress, intestinal obstruction, fecal impaction.

How to manage the interaction:
Although taking Supral 10mg Tablet and Alfentanil together can lead to an interaction, it can be taken if your doctor has suggested it. If you experience any symptoms like feeling tired, having trouble breathing, feeling dizzy or drowsy, difficulty focusing, taking pain or cough medications, constipation, blockage in your intestines, difficulty passing stool, hard or dry stool, less frequent bowel movements, stomach problems, feeling sick, feeling bloated, having stomach pain, or swelling contact the doctor immediately. you should avoid driving or operating hazardous machinery until you know how they affect you and do not discontinue any medications without consulting your doctor.
How does the drug interact with Supral 10mg Tablet:
The combined use of Mefloquine and Supral 10mg Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Mefloquine and Supral 10mg Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.

Drug-Food Interactions

verifiedApollotooltip
  • Alcohol: Avoid alcohol, as it can dangerously increase the drowsy and sedating effects of this medicine.
  • Caffeine: Drinks containing high amounts of caffeine can interfere with how your body breaks down Supral 10mg Tablet , potentially altering its levels in your blood.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTIPSYCHOTICS]

FAQs

Supral 10mg Tablet is used to treat schizophrenia and manic depression (bipolar disorder).
Supral 10mg Tablet contains Olanzapine which works by balancing the chemical messengers like dopamine and serotonin located in the brain, improving mood, behaviour and thoughts.
Supral 10mg Tablet should be used with caution in the medical history of allergic reactions, liver or kidney diseases, heart problems, breathing problems, Alzheimer's disease, high cholesterol, glaucoma, diabetes, stomach/intestinal problems, breathing problem during sleep (sleep apnea), low white blood cell count, breast cancer, enlarged prostate, or fits. Please let your doctor know if you have any other medical problems before starting Supral 10mg Tablet .
Supral 10mg Tablet may make you sweat less and can likely cause heart stroke. Hence, limiting activities that cause overheating, like an exercise in hot weather or using hot tubs, is advised. Drink plenty of fluids and dress lightly.
Supral 10mg Tablet may cause dizziness. It is advised to avoid getting up too fast from a sitting or lying position that can make you feel dizzy.
Olanzapine can cause side effects like orthostatic hypotension (sudden lowering in blood pressure leading to dizziness on standing). If you experience this, do not try to stand up suddenly or start walking; instead, lie down and get up slowly only when you feel better. People taking Supral 10mg Tablet are advised to regularly monitor their blood pressure levels to avoid such unpleasant events. It is also advised to be aware of a condition called tardive dyskinesia (uncontrolled movements of the face, lips, mouth, tongue, arms or legs) that may rarely occur while using this medicine.
No, Supral 10mg Tablet is not a sleeping aid. It's an antipsychotic medication used to treat bipolar disorder and schizophrenia, not insomnia. If you need help with sleep, consult your healthcare provider or pharmacist for appropriate guidance and treatment.
Supral 10mg Tablet is an antipsychotic medication that takes time to start working. It may take several weeks (typically 4-6 weeks or longer) to notice significant symptom improvements. Be patient and consistent with your medication regimen, and schedule regular follow-ups with your healthcare provider to monitor progress and adjust the treatment plan as needed. They will help you assess the medication's effectiveness and make any necessary adjustments.
Do not stop taking Supral 10mg Tablet suddenly; otherwise, your symptoms may return. If you need to stop taking olanzapine, your doctor will help you come off it by gradually reducing your dose. This will help prevent withdrawal symptoms.
There are no adequate, well-controlled studies in pregnant women. Please inform your doctor before taking Supral 10mg Tablet if you are pregnant or planning pregnancy. Your doctor will weigh the potential risks and benefits before prescribing Supral 10mg Tablet .
Supral 10mg Tablet is not indicated for use in children and adolescents under 18. Please seek medical advice.
Supral 10mg Tablet may cause dizziness or drowsiness. To ensure your safety, avoid driving or operating machinery if you're not mentally alert or experiencing symptoms that affect your concentration.
Yes, many people use Supral 10mg Tablet for extended periods, including several months or years, without any problems. However, it's important to remember that you should only take Supral 10mg Tablet as your healthcare provider prescribes. Regular monitoring and follow-up appointments with your healthcare provider are crucial to ensure the medication's safety and effectiveness. Your healthcare provider may also adjust your dosage or switch you to a different medication if needed.
When you start taking olanzapine, you may feel more relaxed and calmer. Within 2-3 weeks, you may notice improvements in your symptoms. Olanzapine can help you focus and think more clearly, stay on top of tasks, remember things more easily, connect with others, and distinguish between reality and delusions. It may also reduce or stop hearing voices.
Avoid drinking alcohol while taking olanzapine, especially during the initial treatment phase. Alcohol can exacerbate the medication's side effects, making you feel drowsy and unsteady. Excessive or daily alcohol consumption can worsen your symptoms and reduce the effectiveness of olanzapine. To ensure your safety and the medication's efficacy, it's best to abstain from alcohol or consult your healthcare provider for guidance.
Supral 10mg Tablet is not typically used to treat anxiety, although some research has explored its potential in this area. It has not been approved for anxiety treatment, and your doctor will usually prescribe other medications as a first-line treatment for anxiety; however, if you're experiencing anxiety in conjunction with another condition that olanzapine is approved to treat, such as bipolar disorder or schizophrenia. In that case, your doctor may consider it part of your overall treatment plan.
The common side effects of the Supral 10mg Tablet are nausea, vomiting, diarrhea, constipation, sores in the mouth and throat, pain, burning, or tingling in the hands or feet, pain, itching, redness, swelling, blisters, or sores in the place where the medication was injected, hair loss, pain, weakness, loss in ability to taste food. However, these symptoms vanish as your body adjusts to the medication. If these symptoms become worse, please consult a doctor for relief.
Taking Supral 10mg Tablet during pregnancy requires careful consideration. It may cause withdrawal symptoms or movement issues in newborns if taken during the third trimester. Talk to your doctor to weigh the benefits against the potential risks for you and your baby.
Yes, weight gain is a common side effect of Supral 10mg Tablet because it can increase your appetite and affect your metabolism. Eating a balanced diet and exercising regularly can help manage this, but you should talk to your doctor for personalised advice.
Yes, but you should keep your caffeine intake consistent. Sudden changes in how much coffee or tea you drink can change the level of Supral 10mg Tablet in your blood, making it either less effective or increasing side effects. Talk to your doctor or pharmacist if you plan to make major changes to your caffeine habits.
No, you should not stop taking this medicine suddenly, even if you feel completely well. Stopping abruptly can cause your symptoms to return or lead to withdrawal effects. If you want to stop, talk to your doctor, who will guide you on gradually decreasing your dose.
Yes, drowsiness and sleepiness are very common when starting Supral 10mg Tablet . This effect usually decreases over time, but you should avoid driving or operating machinery until you know how this medicine affects you. Talk to your doctor if the sleepiness is severe or does not improve.
Yes, you can take Supral 10mg Tablet with or without food. Taking it with food can sometimes help if the medicine makes you feel slightly nauseous. Talk to your doctor or pharmacist if you have trouble swallowing the tablets.
Yes, Supral 10mg Tablet can increase blood sugar levels and may lead to diabetes or worsen existing diabetes. Your doctor will likely order regular blood tests to monitor your sugar levels while you are on this medication. Talk to your doctor if you experience extreme thirst or frequent urination.

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Country of origin

INDIA

Manufacturer/Marketer address

F1/4 Okhla Industrial Area, Phase1, Near Honda Show room, New Delhi - 110020.
Other Info - SUP0212
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