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  3. Sy Gnolex 300mg Capsule

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Sy Gnolex 300mg Capsule, Pack of 1 Capsule
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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Sy Gnolex 300mg Capsule is used in the prevention of neuropathic pain, epilepsy (seizure episodes), and fibromyalgia (musculoskeletal pain). It contains pregabalin, which works by calming damaged or overactive nerves in the body that can cause nerve or musculoskeletal pain or seizures. Additionally, it reduces the number of pain signals transmitted by damaged nerves. It may cause side effects such as dizziness, somnolence (sleepiness or drowsiness), dry mouth, oedema (fluid build-up with swelling), blurred vision, weight gain, and abnormal thinking (difficulty with concentration or attention). Before taking this medicine, you should tell your doctor if you are allergic to any of its components, if you are pregnant or breastfeeding, and provide details about all the medications you are taking and any pre-existing medical conditions.

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Composition :

PREGABALIN-300MG

Consume Type :

ORAL

Return Policy :

Not Returnable

About Sy Gnolex 300mg Capsule

Sy Gnolex 300mg Capsule belongs to a group of medications called anticonvulsants, primarily used for the prevention of neuropathic pain, epilepsy (seizure episodes), and fibromyalgia (musculoskeletal pain). Neuropathic pain is chronic nerve pain usually caused by damaged nerves due to conditions such as diabetes, shingles (a viral infection that causes a painful rash), spinal cord injury, or injuries to tissue, muscles, or joints.

Sy Gnolex 300mg Capsule contains pregabalin, which works by calming damaged or overactive nerves in the body that can cause nerve or musculoskeletal pain or seizures. In addition, it decreases the number of pain signals sent out by damaged nerves.

You should take Sy Gnolex 300mg Capsule for as long as your doctor has prescribed it, based on your medical condition. You may experience certain common side effects, such as dizziness, somnolence (sleepiness or drowsiness), dry mouth, oedema (fluid build-up with swelling), blurred vision, weight gain, and abnormal thinking (difficulty with concentration or attention). Most of these side effects do not require medical attention. However, if they persist or worsen, consult your doctor.

Before taking Sy Gnolex 300mg Capsule, inform your doctor if you are allergic to any of its ingredients. Tell your doctor if you experience any symptoms of suicidal thoughts or behaviour while taking Sy Gnolex 300mg Capsule. Also, inform your doctor if you have a history of alcohol or drug addiction, mood disorders, bleeding disorders, chronic obstructive pulmonary disease (COPD), diabetes, or kidney, liver, or heart disease. Sy Gnolex 300mg Capsule is not recommended during pregnancy or breastfeeding unless specifically advised by your doctor. It should not be given to children under 18 years of age, as its safety and effectiveness have not been established in this age group.

Uses of Sy Gnolex 300mg Capsule

Sy Gnolex 300mg Capsule is used in the treatment of Neuropathic pain, Epilepsy (seizures/fits) and Fibromyalgia (musculoskeletal pain). The detailed uses of Sy Gnolex 300mg Capsule are as follows:<br/> • Neuropathic Pain Relief: Sy Gnolex 300mg Capsule is frequently recommended to treat nerve pain caused by conditions like postherpetic neuralgia, diabetic neuropathy, or spinal cord injury.<br/> • Epilepsy management: It helps regulate seizure activity and can be used as an adjuvant therapy for people with partial seizures.<br/> • Fibromyalgia Treatment: It could enhance general quality of life by reducing the pervasive pain and suffering brought on by fibromyalgia.<br/> • Generalized Anxiety Disorder (GAD): Sy Gnolex 300mg Capsule reduces excessive worry and relaxes the nervous system to treat anxiety problems.<br/> • Post-Traumatic Stress Disorder (PTSD): In order to help manage the symptoms of Post-Traumatic Stress Disorder (PTSD), Sy Gnolex 300mg Capsule can be administered to relieve anxiety and related conditions.<br/>

Directions for Use

  • Sy Gnolex 300mg Capsule can be taken with or without food, as advised by your doctor.
  • Your doctor will determine the dosage and timing of this medication based on your medical condition.
  • Swallow Sy Gnolex 300mg Capsule as a whole with a glass of water.
  • Do not crush, chew, break, or open it.

Medicinal Benefits

Sy Gnolex 300mg Capsule belongs to a group of medications called anticonvulsants, which are used to prevent neuropathic pain (pain caused by damaged nerves), fibromyalgia (musculoskeletal pain), and epilepsy (characterised by seizures or fits). It contains pregabalin, which works by calming damaged or overactive nerves in the body that can cause nerve or musculoskeletal pain or seizures. Additionally, it reduces the number of pain signals transmitted by damaged nerves.

How Sy Gnolex 300mg Capsule Works

Sy Gnolex 300mg Capsule contains Pregabalin, which works by calming the damaged or overactive nerves in the body that may cause nerve or musculoskeletal pain or seizures. Besides this, it also decreases the number of pain signals sent out by damaged nerves in the body.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Sy Gnolex 300mg Capsule
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Wear compression garments like stockings, sleeves, or gloves to apply pressure and help stop fluid from building up, especially after the swelling goes down.
  • Move around and do exercises to help the fluid circulate, especially in swollen limbs. Ask your doctor for specific exercises.
  • Raise the swollen area above your heart level several times a day, even while sleeping, to help reduce swelling.
  • Gently massage the swollen area with firm but not painful pressure.
  • Keep the swollen area clean and moisturized to prevent injury and infection.
  • Reduce salt intake to help prevent fluid from building up and worsening the swelling, as advised by a doctor.
  • If the swelling does not get better after a few days of home treatment or worsens, consult your doctor right away.
  • Confusion is a major psychotic disorder that needs immediate medical attention.
  • Acknowledge your experience and put effort to control confusion.
  • Avoid smoking and alcohol intake as it can worsen the condition and increase your confusion.
  • Practice meditation and yoga to avoid anxiety, which can be one of the leading causes.
  • Talk to your dietician and consume food that can improve your mental health.
  • Blood flow to the brain and the rest of the body is increased by physical activity. This could help you maintain your memory.
  • Reading, solving puzzles, and picking up new skills are examples of mental workouts that can keep the brain engaged and enhance memory retention.
  • Maintaining an active social life enhances memory and brain stimulation.
  • Relaxation methods like yoga, meditation, and deep breathing can help because long-term stress can affect memory.
  • Drink plenty of water and stay hydrated.
  • Limit the intake of alcohol and caffeine.
  • Maintain good hygiene habits.
  • Avoid holding on and empty the bladder at regular intervals.
  • Try to quit smoking.
  • Perform balance exercises like heel raises, standing on one leg, and weight shifts with the guidance of a physical therapist.
  • Focus on strengthening leg muscles and core muscles for better stability.
  • Stay hydrated by drinking plenty of water as dehydration may lead to unsteadiness and dizziness.
  • Wear low-heeled shoes with good tread for better grip.
  • Change your surroundings by removing tripping hazards like clutter, loose rugs and poorly lit areas.
  • Avoid sudden position changes; stand up slowly and take your time to move around.
  • Watch out for rapid head movements that might trigger dizziness.
  • Eat fiber-rich foods, fruits, and vegetables, and track your food intake to monitor calorie consumption.
  • Limit takeout and restaurant meals, and weigh yourself weekly to stay motivated.
  • Build balanced meals, allow yourself to enjoy treats in moderation, and prioritize sleep and stress management through exercise and relaxation techniques.

What if I have taken an overdose of Sy Gnolex 300mg Capsule

Do not take more than the prescribed dose of Sy Gnolex 300mg Capsule, as it may cause an overdose. The symptoms of an overdose include sleepiness, confusion, agitation, restlessness, seizures (fits), and coma. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Do not take Sy Gnolex 300mg Capsule if you are known to be allergic to any of its ingredients. Do not stop taking Sy Gnolex 300mg Capsule without consulting your doctor, as this may cause withdrawal symptoms. Inform your doctor if you experience any symptoms of suicidal thoughts or behaviour while taking Sy Gnolex 300mg Capsule. Also, let your doctor know if you have a history of alcohol or drug addiction, mood disorders, bleeding disorders, chronic obstructive pulmonary disease (COPD), diabetes, or kidney, liver, or heart disease before starting Sy Gnolex 300mg Capsule. Sy Gnolex 300mg Capsule is not recommended during pregnancy or breastfeeding unless specifically advised by your doctor. It should not be given to children under 18 years of age, as its safety and effectiveness have not been established in this age group. Sy Gnolex 300mg Capsule may cause decreased concentration, drowsiness, and dizziness, so avoid driving or operating machinery unless you are fully alert. Avoid consuming alcohol while taking Sy Gnolex 300mg Capsule, as it may worsen side effects such as dizziness and drowsiness.

Drug-Drug Interactions

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PregabalinRemifentanil
Severe
PregabalinHydromorphone
Severe

Drug-Drug Interactions

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PregabalinRemifentanil
Severe
How does the drug interact with Sy Gnolex 300mg Capsule:
Using Sy Gnolex 300mg Capsule together with Remifentanil causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking remifentanil and Sy Gnolex 300mg Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinHydromorphone
Severe
How does the drug interact with Sy Gnolex 300mg Capsule:
Using Sy Gnolex 300mg Capsule together with Hydromorphone causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Hydromorphone and Sy Gnolex 300mg Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinBuprenorphine
Severe
How does the drug interact with Sy Gnolex 300mg Capsule:
Using Sy Gnolex 300mg Capsule together with Buprenorphine causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Buprenorphine and Sy Gnolex 300mg Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience dizziness, drowsiness, difficulty concentrating, and impairment in- judgment, reaction speed and motor coordination, consult the doctor immediately. Avoid driving or operating dangerous machinery. Do not exceed the doses, frequency, or duration of usage advised by the doctor. Do not discontinue any medications without consulting a doctor.
PregabalinFentanyl
Severe
How does the drug interact with Sy Gnolex 300mg Capsule:
Using Sy Gnolex 300mg Capsule together with Fentanyl can increase the risk of side effects.

How to manage the interaction:
Although taking fentanyl together with Sy Gnolex 300mg Capsule can result in an interaction, they can be taken together if prescribed by a doctor. However, consult a doctor if you have dizziness, sleepiness, difficulty concentrating, or impairment in judgment. Do not stop taking any medication without consulting a doctor.
PregabalinPentazocine
Severe
How does the drug interact with Sy Gnolex 300mg Capsule:
Using Sy Gnolex 300mg Capsule together with Pentazocine causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking pentazocine and Sy Gnolex 300mg Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinSufentanil
Severe
How does the drug interact with Sy Gnolex 300mg Capsule:
Using Sy Gnolex 300mg Capsule together with Sufentanil causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking sufentanil and Sy Gnolex 300mg Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinNalbuphine
Severe
How does the drug interact with Sy Gnolex 300mg Capsule:
Using Sy Gnolex 300mg Capsule together with Nalbuphine causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking Nalbuphine and Sy Gnolex 300mg Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinDezocine
Severe
How does the drug interact with Sy Gnolex 300mg Capsule:
Using Sy Gnolex 300mg Capsule together with Dezocine causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking Dezocine and Sy Gnolex 300mg Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinButorphanol
Severe
How does the drug interact with Sy Gnolex 300mg Capsule:
Using Sy Gnolex 300mg Capsule together with Butorphanol causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Butorphanol and Sy Gnolex 300mg Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. If you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinMethadone
Severe
How does the drug interact with Sy Gnolex 300mg Capsule:
Using Sy Gnolex 300mg Capsule together with Methadone causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking methadone and Sy Gnolex 300mg Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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PREGABALIN-300MGHerbal products/medicines
Moderate

Drug-Food Interactions

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PREGABALIN-300MGHerbal products/medicines
Moderate
Common Foods to Avoid:
St. John’S Wort

How to manage the interaction:
Taking St. John's wort during Sy Gnolex 300mg Capsule treatment may increase the risk of side effects such as dizziness, drowsiness, confusion, and difficulty concentrating, impairment in thinking, judgment, and motor coordination. Avoid St. John's wort during treatment with Sy Gnolex 300mg Capsule.

Diet & Lifestyle Advise

  • Maintain a diet rich in fruits, vegetables, whole grains, and omega-3-rich foods.
  • Avoid fried foods, high-fat dairy products, pastries, and processed foods, as they may worsen neuropathic pain.
  • Include cayenne pepper in your diet, as it can help reduce neuropathic pain.
  • Exercising regularly helps maintain weight and improve overall health.
  • Rest well; get plenty of sleep.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress, decrease pain sensitivity, and improve coping skills.
  • Have a seizure response plan that helps those around you know what to do.
  • Prepare your living area; small changes may help reduce the risk of physical injury during a seizure.
  • Install an alarm or emergency device to get assistance during a seizure attack.

Habit Forming

Yes

Therapeutic Class

ANTICONVULSANT

Sy Gnolex 300mg Capsule Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

Avoid consuming alcohol while taking Sy Gnolex 300mg Capsule, as it may worsen the side effects like dizziness and drowsiness.

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Pregnancy

Caution

Sy Gnolex 300mg Capsule is a category C pregnancy drug. Please consult your doctor if you are pregnant before starting Sy Gnolex 300mg Capsule. Your doctor will weigh the benefits and potential risks before prescribing Sy Gnolex 300mg Capsule.

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Breast Feeding

Caution

Sy Gnolex 300mg Capsule should not be used during breastfeeding unless prescribed by a doctor. Your doctor will weigh the benefits and potential risks before prescribing Sy Gnolex 300mg Capsule.

bannner image

Driving

Unsafe

Sy Gnolex 300mg Capsule may cause decreased concentration, drowsiness, and dizziness; therefore, avoid driving or operating machinery unless you are fully alert.

bannner image

Liver

Caution

Take Sy Gnolex 300mg Capsule with caution, especially if you have or had a history of liver disease/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Sy Gnolex 300mg Capsule with caution, especially if you have or had a history of kidney disease/conditions. The dose may be adjusted by your doctor as required.

bannner image

Children

Unsafe

Sy Gnolex 300mg Capsule is not recommended for children below the age of 18 years, as its safety and effectiveness have not been established in this age group.

Have a query?

FAQs

Sy Gnolex 300mg Capsule belongs to a group of medications called "anticonvulsants", primarily used in the prevention of neuropathic pain, epilepsy (seizure episodes), and fibromyalgia (musculoskeletal pain).

Sy Gnolex 300mg Capsule contains Pregabalin, which works by calming the damaged or overactive nerves in the body that may cause nerve or musculoskeletal pain or seizures. Besides this, it also decreases the number of pain signals sent out by damaged nerves in the body.

Yes, Sy Gnolex 300mg Capsule may cause weight gain because it increases your hunger. However, regular physical exercise and a balanced diet with low-calorie food may help you keep your weight stable. Please consult your doctor if you have any further concerns about keeping your weight stable.

No, you are not recommended to take Sy Gnolex 300mg Capsule with tramadol, as co-administration of these medicines may cause breathing problems, drowsiness, and even lead to a state of coma. So, before using Sy Gnolex 300mg Capsule with painkillers like oxycodone or any other opioid analgesics, you are advised to contact your doctor so that the dosage may be adjusted accordingly to use safely.

No, Sy Gnolex 300mg Capsule is not a normal painkiller. It is an anticonvulsant that helps treat neuropathic pain, musculoskeletal pain, and epilepsy (seizures).

Do not discontinue Sy Gnolex 300mg Capsule without consulting your doctor, as it might cause withdrawal symptoms. The doctor will reduce the dose gradually to prevent withdrawal symptoms.

Neuropathic pain occurs due to nerve damage while muscle pain occurs due to spasms or injury. Neuropathic pain is chronic and is felt as tingling and burning sensation. Whereas, muscle pain is a dull ache and will generally get better within a few days unless it is a severe injury.

Sy Gnolex 300mg Capsule works in different ways for each disease. For neuropathic and musculoskeletal pain, it calms the damaged or overactive nerves and decreases pain signals sent out by damaged nerves in the body. In case of epilepsy, it reduces abnormal electrical activity in the brain.

Sy Gnolex 300mg Capsule starts working within a week and you may notice its full benefits in a few weeks. Continue taking Sy Gnolex 300mg Capsule for the prescribed duration for effective results.

Sy Gnolex 300mg Capsule should be taken for as long as it has been prescribed by the doctor. The doctor will determine the duration of the treatment based on your condition.

Sy Gnolex 300mg Capsule may be addictive. Therefore, take Sy Gnolex 300mg Capsule only for the prescribed duration. Do not take Sy Gnolex 300mg Capsule for a prolonged time as it may lead to mental or physical dependence.

Taking Sy Gnolex 300mg Capsule with diazepam may increase side effects such as dizziness, confusion, drowsiness and difficulty concentrating. Hence, consult the doctor before taking diazepam with Sy Gnolex 300mg Capsule.

Sy Gnolex 300mg Capsule may cause common side effects, such as dizziness, somnolence (sleepiness/drowsiness), dry mouth, oedema (fluid overload with swelling), blurred vision, weight gain, and abnormal thinking (difficulty with concentration/attention). Most of these side effects do not require medical attention and will gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Country of origin

India
Other Info - SY84417

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jul 22, 2025 | 9:02 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/021446s035,022488s013lbl.pdf
  2. https://www.medicines.org.uk/emc/product/1761/pil
  3. https://www.drugs.com/pregabalin.html
  4. https://medlineplus.gov/druginfo/meds/a605045.html
  5. https://www.nhs.uk/medicines/pregabalin/
  6. https://www.ema.europa.eu/en/documents/product-information/pregabalin-sandoz-epar-product-information_en.pdf
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