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Syncapone 100 Tablet is used in treating Parkinson's disease with its symptoms including tremors, spasms, muscle stiffness and poor muscle control. It helps to control movement and provides greater relief from the symptoms of Parkinson's disease. It may cause common side effects such as nausea, vomiting, loss of appetite, light-headedness, lowered blood pressure, confusion, and dyskinesia (uncontrolled/involuntary muscle movement). Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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About Syncapone 100 Tablet
Syncapone 100 Tablet is used in treating Parkinson's disease with its symptoms including tremors, spasms, muscle stiffness and poor muscle control. Parkinson's disease is a disorder of the central nervous system that affects movement and locomotion, which causes stiffness, shaking, and difficulty in walking, coordination and balance. In Parkinson's patients, there are low dopamine levels as the nerve cells of the brain (neurons) that produce dopamine begin to die.
Syncapone 100 Tablet contains Carbidopa, Levodopa, and Entacapone. Levodopa belongs to the central nervous system agents, while Carbidopa is a decarboxylase inhibitor. The medicinal component Levodopa changes into dopamine in the brain and helps to control movement. Carbidopa prevents the breakdown of Levodopa in the bloodstream so that more Levodopa can reach the brain. On the other hand, Entacapone belongs to a class of COMT (catechol-o-methyltransferase enzyme) inhibitors which causes higher and more sustained levels of Levodopa in the blood that more Levodopa can reach the brain, leading to greater relief from the symptoms of Parkinson's disease.
Take Syncapone 100 Tablet as prescribed by your doctor. You are suggested to take $ame as long as your doctor has prescribed it after checking your medical condition. The most common side effects of Syncapone 100 Tablet are nausea, vomiting, loss of appetite, light-headedness, lowered blood pressure, confusion, and dyskinesia (uncontrolled/involuntary muscle movement). Most of these side effects of Syncapone 100 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
If you are known to be allergic to Syncapone 100 Tablet or any other medicines, please tell your doctor. Do not take Syncapone 100 Tablet if you are pregnant or breastfeeding unless prescribed by the doctor. Syncapone 100 Tablet should not be given to children as safety and effectiveness have not been established. Syncapone 100 Tablet may cause hallucinations (seeing or hearing things that are not there) in some cases if taken for a prolonged time. So, if you experience hallucinations while taking Syncapone 100 Tablet , please talk to your doctor immediately. Keep your doctor informed about your medicines and health condition and rule out any side effects.
Uses of Syncapone 100 Tablet
Directions for Use
Medicinal Benefits
Syncapone 100 Tablet is an antiparkinson agent that is used in the treatment of Parkinson’s disease. Syncapone 100 Tablet is a combination of three medicines: Carbidopa, Levodopa, and Entacapone. Levodopa belongs to the class of medications named central nervous system agents, While Carbidopa falls in decarboxylase inhibitors. The medicinal component Levodopa changes into dopamine in the brain and helps to control movement. At the same time, Carbidopa acts by preventing the breakdown of Levodopa in the bloodstream so that more Levodopa can effectively reach the brain to block acetylcholine (a chemical messenger in the brain). Entacapone blocks a certain natural substance, catechol-o-methyltransferase (COMT) (an enzyme that breaks down the levodopa in the body), which causes higher and more sustained levels of levodopa in the blood, so that more Levodopa can reach the brain, leading to greater relief from the symptoms of Parkinson’s disease. This effect allows the levodopa to last longer in the body so that it doesn't wear off before the next dose.
How Syncapone 100 Tablet Works
Storage
What if I have taken an overdose of Syncapone 100 Tablet
Drug Warnings
Do not stop taking Syncapone 100 Tablet suddenly without talking to your doctor. It may result in a serious neuroleptic malignant syndrome (NMS) that causes fever, muscle cramps or stiffness, unusual body movements, fast heartbeat, sweating, change in thinking, and confusion. Do not take Syncapone 100 Tablet if you are allergic to Syncapone 100 Tablet or any of its ingredients. Tell your doctor if you have any medical history of diabetes, heart attacks, mental illness, stomach ulcers, heart disease, or have recently undergone a surgical procedure. Syncapone 100 Tablet may cause dizziness, lightheadedness, and fainting when you get up too quickly from a lying position, especially when you start taking Syncapone 100 Tablet so please get up gradually. Besides this, a prolonged intake of Syncapone 100 Tablet may lead to greater neuropathy chances (nerve damage). Syncapone 100 Tablet should be given with caution in patients with eye problems (narrow-angle glaucoma), irregular heartbeat (arrhythmia), gastrointestinal bleeding, and psychosis. The use of Syncapone 100 Tablet is restricted if a person takes monoamine oxidase inhibitors (MAOs) or antidepressant drugs like isocarboxazid, phenelzine, selegiline, and tranylcypromine because it can lead to high blood pressure (hypertension) crisis.
Drug-Drug Interactions
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Diet & Lifestyle Advise
Drink plenty of water to avoid headaches due to dehydration.
Limit the consumption of sugar-containing food or food with too many calories but fewer nutrients, as it may cause tooth decay.
Engaging in physical activity like dancing or exercising will boost the metabolism and make a person more energetic.
Avoid intake of alcoholic beverages with Syncapone 100 Tablet as it can make a person dehydrated and may affect their sleep. This can make it harder for a person’s body to aid the Syncapone 100 Tablet in fighting off infections.
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Therapeutic Class
Product Substitutes
Alcohol
Caution
Avoid consumption of alcohol with Syncapone 100 Tablet as it may increase the risk of adverse effects such as drowsiness, dizziness, or difficulty in concentrating.
Pregnancy
Caution
Syncapone 100 Tablet is a pregnancy Category C medicine. It is unknown whether Syncapone 100 Tablet will affect pregnant women or fetus. Hence, the intake of Syncapone 100 Tablet should be avoided if you are pregnant or planning to become pregnant, as it may harm the baby.
Breast Feeding
Caution
Syncapone 100 Tablet is excreted in human milk, but the effect of Syncapone 100 Tablet on an infant is unknown. So, Syncapone 100 Tablet is given to a breastfeeding mother only if the doctor thinks the benefits outweigh the risks.
Driving
Unsafe
Syncapone 100 Tablet may cause drowsiness and make you fall asleep suddenly. Therefore, avoid driving if you feel drowsy after taking Syncapone 100 Tablet .
Liver
Caution
Take Syncapone 100 Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.
Kidney
Caution
Take Syncapone 100 Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.
Children
Caution
Syncapone 100 Tablet is not recommended for use in children, as safety and effectiveness have not been established.
Have a query?
Syncapone 100 Tablet is used in the treatment of Parkinson's disease and helps relieve symptoms, including tremors, spasms, muscle stiffness and poor muscle control.
Syncapone 100 Tablet is a combination of three medicines namely; Carbidopa, Levodopa, and Entacapone. Levodopa belongs to the class of medications name as central nervous system agents, While Carbidopa fall in the category of decarboxylase inhibitors. The medicinal component Levodopa changes into dopamine in the brain and helps to control movement. While Carbidopa and Entacapone act by preventing the breakdown and causes higher and more sustained levels of Levodopa in the bloodstream so that more Levodopa can reach to brain.
Take Syncapone 100 Tablet medicine precisely as the doctor has directed. Take one dose on a regular basis. Try to take the tablets at the same time of day every day, as this will assist you in making sure to take them.
In some cases, prolonged intake of Syncapone 100 Tablet may lead to autoimmune hemolytic anaemia (red blood cells in the blood are destroyed earlier than normal). Levodopa in Syncapone 100 Tablet can cause the immune system to mistake your own red blood cells for foreign substances. The body responds by making antibodies to attack the body's own red blood cells. The antibodies attach to red blood cells and cause them to break down too early. So, your doctor might recommend regular blood tests while using Syncapone 100 Tablet .
You are recommended to avoid taking protein-rich food (such as chicken, beef, pork, eggs, meats, fish, dairy products, seeds, and nuts), iron supplements, or multivitamin tablets while taking Syncapone 100 Tablet as it may delay and reduce the absorption of levodopa. Thus, reduce the effectiveness of Syncapone 100 Tablet . Please consult your doctor and do as advised for the best results.
Yes, orthostatic hypotension could be a side-effect of Syncapone 100 Tablet . Orthostatic hypotension is a sudden lowering in blood pressure leading to dizziness on standing. If you experience this, do not try to stand up suddenly or start walking, instead lie down and get up slowly only when you feel better. People taking Syncapone 100 Tablet are advised to regularly monitor their blood pressure levels to avoid unpleasant events.
Consult your doctor before taking Syncapone 100 Tablet if you have glaucoma. Syncapone 100 Tablet is contraindicated in patients with narrow-angle glaucoma. Syncapone 100 Tablet may cause blindness on long-term use in the case of patients with narrow-angle glaucoma.
Hallucination is a medical condition in which the person may feel, hear, or believe things that are not true, see things that are not there, or feel unusually suspicious or confused. Syncapone 100 Tablet may cause hallucinations in some cases if taken for a prolonged time. So, if you experience hallucinations while taking Syncapone 100 Tablet , please talk to your doctor immediately.
It is advised not to stop taking Syncapone 100 Tablet without consulting your doctor as it may lead to a severe condition called withdrawal-emergent hyperpyrexia with symptoms such as confusion, fever, muscle stiffness, changes in heartbeat, and breathing. Therefore, take Syncapone 100 Tablet for as long as your doctor has prescribed it and if you experience any of these symptoms while taking Syncapone 100 Tablet , please consult your doctor so that the dose may be gradually reduced.
Syncapone 100 Tablet can be taken with or without food as advised by your doctor. Stay away from protein meals as it can delay the action of Syncapone 100 Tablet .
Yes, Syncapone 100 Tablet can turn the colour of your urine, sweat and saliva dark (brown, red, or black). Although it not harmful, it can sometimes stain your bedding and clothes.
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