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  3. Synfovir Tablet

Synfovir Tablet, Pack of 1 Tablet
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Synfovir Tablet is used to treat HIV and chronic hepatitis B infection. It contains Tenofovir disoproxil fumarate which works by preventing the development of the virus in the human body. In some cases, this medicine may cause side effects such as diarrhoea, rash, nausea, pain, weakness, and stomach pain. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Composition :

TENOFOVIR DISOPROXIL FUMARATE-300MG

Manufacturer/Marketer :

Synmedic Laboratories

Consume Type :

ORAL

Return Policy :

Not Returnable

About Synfovir Tablet

Synfovir Tablet belongs to the group of medicines known as ‘antiviral medicines’ used to control HIV infection and chronic hepatitis B infection. Human immunodeficiency virus (HIV) is a sexually transmitted infection that over time leads to acquired immunodeficiency syndrome (AIDS). Chronic hepatitis B is a long-term viral infection caused by the hepatitis B virus.

Synfovir Tablet contains ‘Tenofovir disoproxil fumarate’ which is an antiviral/HIV medicine and works by prevents the development of the virus in human cells. This prevents the virus from producing new viruses and cleans up your infection. It can effectively reduce the symptoms associated with HIV and chronic hepatitis B infection.

Take Synfovir Tablet as prescribed by your doctor. Your doctor will recommend how often you take Synfovir Tablet based on your medical condition. Some people may experience diarrhea, rash, nausea, pain, weakness, and stomach pain. Most of these side effects of Synfovir Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Synfovir Tablet should not be taken if you are allergic to Synfovir Tablet or any other contents present in it. Patients should take necessary precautions to avoid infecting others. This medicine should not be given to adolescents with a history of kidney failure. If you have liver disease including hepatitis B or C, then you should not take this Synfovir Tablet. Inform your doctor if you are pregnant, planning to become pregnant, and breastfeeding. Avoid drinking alcohol as it may increase the risk of side effects. It is advisable to avoid driving while using Synfovir Tablet as Synfovir Tablet may cause dizziness that may affect the ability to drive or use machines. Synfovir Tablet should not be used for children less than 12 years of age.

Uses of Synfovir Tablet

Treatment of HIV infections, Chronic hepatitis.

Directions for Use

Take Synfovir Tablet with or without food as prescribed by the doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.

Medicinal Benefits

Synfovir Tablet belongs to the group of medications called ‘antiretroviral drugs’ used to control HIV infection and chronic hepatitis B. Synfovir Tablet decreases the amount of HIV in your body. Therefore, your immune system may work better. This reduces your chance of getting complications of HIV like new infections, cancer and enhances your quality of life. Synfovir Tablet works by prevents the development of viruses in human cells. This prevents the virus from producing new viruses and cleans up your infection. It can effectively reduce the symptoms associated with HIV and chronic hepatitis B infection.

How Synfovir Tablet Works

Synfovir Tablet contains ‘Tenofovir disoproxil fumarate’ which is an antiviral/HIV medicine and works by prevents the development of the virus in human cells. This prevents the virus from producing new viruses and cleans up your infection. It can effectively reduce the symptoms associated with HIV and chronic hepatitis B infection.

Storage

Store in a cool and dry place away from sunlight
Side effects of Synfovir Tablet
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Apply a hot/cold pack to the affected area.
  • Doing gentle exercises can help cope with pain by stretching muscles.
  • Get enough sleep. It helps enhance mood and lower pain sensitivity.
  • Avoid alcohol, smoking and tobacco as they can increase pain.
  • Follow a well-balanced meal.
  • Meditation and massages may also help with pain.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Managing back pain as a side effect of medication requires a combination of self-care techniques, lifestyle modifications, and medical interventions. Here are the steps:
  • Talk to your doctor about your back pain and potential medication substitutes or dose changes.
  • Try yoga or Pilates and other mild stretching exercises to increase flexibility and strengthen your back muscles.
  • To lessen the tension on your back, sit and stand upright and maintain proper posture.
  • To alleviate discomfort and minimize inflammation, apply heat or cold packs to the afflicted area.
  • Under your doctor's supervision, think about taking over-the-counter painkillers like acetaminophen or ibuprofen.
  • Make ergonomic adjustments to your workspace and daily activities to reduce strain on your back.
  • To handle tension that could make back pain worse, try stress-reduction methods like deep breathing or meditation.
  • Use pillows and a supportive mattress to keep your spine in the right posture as you sleep.
  • Back discomfort can worsen by bending, twisting, and heavy lifting.
  • Speak with a physical therapist to create a customized training regimen to increase back strength and flexibility.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

What if I have taken an overdose of Synfovir Tablet

Avoid exceeding the recommended dose as it might cause an overdose. Seek immediate medical attention if you experience any unusual symptoms.

Drug Warnings

Synfovir Tablet should not be taken if you are allergic to Synfovir Tablet or any other contents present in it. Synfovir Tablet should not be taken in the conditions like liver disease, bone problems kidney disease. This medicine should not be given to adolescents with a history of kidney failure. Synfovir Tablet does not decrease the chances of passing infections to others. Inform your doctor before taking Synfovir Tablet if you observe any symptoms of infection or other symptoms like weakness beginning in the hands and feet, muscle weakness and moving up towards the trunk of the body, palpitations (racing or skipping heartbeat), hyperactivity and tremor. Patients should take necessary precautions to avoid infecting others. Inform your doctor if you are pregnant, planning to become pregnant and breastfeeding. Inform your doctor before using Synfovir Tablet if you are older than 65 years of age. Avoid drinking alcohol as it may increase the risk of side effects. It is advisable to you do not drive while using Synfovir Tablet as Synfovir Tablet may cause dizziness that may affect the ability to drive or use machines. Synfovir Tablet should not be used for children less than 12 years of age.

Drug-Drug Interactions

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Tenofovir disoproxilDidanosine
Critical
Tenofovir disoproxilStreptozocin
Critical

Drug-Drug Interactions

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Tenofovir disoproxilDidanosine
Critical
How does the drug interact with Synfovir Tablet:
Coadministration of Didanosine with Synfovir Tablet can increase the levels and risk of Didanosine side effects.

How to manage the interaction:
Taking Didanosine with Synfovir Tablet is not recommended, please consult your doctor before taking it. It can be taken if your doctor prescribes it. However, if you experience severe headaches, confusion, weakness, trouble walking, muscle pain, or high fever, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Tenofovir disoproxilStreptozocin
Critical
How does the drug interact with Synfovir Tablet:
Combining Synfovir Tablet and Streptozocin can increase the risk of kidney problems.

How to manage the interaction:
Taking Synfovir Tablet with Streptozocin is not recommended, as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without talking to your doctor.
Tenofovir disoproxilDeferoxamine
Severe
How does the drug interact with Synfovir Tablet:
Coadministration of Deferoxamine with Synfovir Tablet can increase the risk of kidney problems.

How to manage the interaction:
Taking Deferoxamine and Synfovir Tablet together can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
Tenofovir disoproxilMethotrexate
Severe
How does the drug interact with Synfovir Tablet:
Coadministration of Synfovir Tablet with Methotrexate may increase the levels and side effects of Synfovir Tablet.

How to manage the interaction:
Although there is a possible interaction between Synfovir Tablet and methotrexate, you can take these medicines when prescribed by your doctor. However, if you experience any symptoms such as vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, breathing difficulty, or dizziness, consult your doctor. Do not stop using any medications without consulting a doctor.
Tenofovir disoproxilPolymyxin b
Severe
How does the drug interact with Synfovir Tablet:
Coadministration of Synfovir Tablet with Polymyxin B can increase the risk of side effects.

How to manage the interaction:
Taking Synfovir Tablet with Polymyxin B together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, swelling, difficulty breathing, bone pain, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult a doctor immediately. Do not stop using any medications without consulting a doctor.
Tenofovir disoproxilCisplatin
Severe
How does the drug interact with Synfovir Tablet:
Coadministration of Cisplatin and Synfovir Tablet can increase the risk of kidney damage and reduce kidney function.

How to manage the interaction:
Taking Cisplatin and Synfovir Tablet together can lead to an interaction, it can be taken when advised by your doctor. However, if you experience any symptoms like nausea, vomiting, irregular urination, sudden weight gain or weight loss, shortness of breath, muscle cramps, dizziness, and irregular heart rhythm, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
Tenofovir disoproxilKetoconazole
Severe
How does the drug interact with Synfovir Tablet:
Coadministration of Ketoconazole and Synfovir Tablet may increase the risk of developing liver damage.

How to manage the interaction:
Although taking Ketoconazole and Synfovir Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you have any symptoms like fever, chills, joint pain or swelling, unusual bleeding, fatigue, vomiting, abdominal pain, dark urine, light stools, and/or yellowing of the skin or eyes, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
Tenofovir disoproxilLithium
Severe
How does the drug interact with Synfovir Tablet:
Co-administration of Lithium carbonate with Synfovir Tablet can increase the risk of developing kidney problems.

How to manage the interaction:
Although there is a possible interaction between Synfovir Tablet and Lithium, you can take these medicines when prescribed by your doctor. Consult the doctor immediately if you experience symptoms such as vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, shortness of breath, muscle cramps, or weakness. Do not discontinue any medications without consulting a doctor.
Tenofovir disoproxilPenicillamine
Severe
How does the drug interact with Synfovir Tablet:
Coadministration of Synfovir Tablet with Penicillamine can increase the risk of developing kidney problems.

How to manage the interaction:
Taking Synfovir Tablet with Penicillamine can possibly result in an interaction, it can be taken when your doctor has advised it. However, if you experience vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, shortness of breath, muscle cramps, dizziness, and irregular heart rhythm contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Tenofovir disoproxilPhenytoin
Severe
How does the drug interact with Synfovir Tablet:
Coadministration of Phenytoin and Synfovir Tablet can reduce the levels of Synfovir Tablet, which can lead to low treatment outcomes.

How to manage the interaction:
Taking Synfovir Tablet and Phenytoin together can result in an interaction, but it can be taken if your doctor has advised it. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a diet with fresh fruits and vegetables.
  • Option for lean meat such as skinless chicken and fish. Limit processed and high-sugar foods.
  • Avoid acidic foods such as tomatoes, lemons, and oranges.
  • Limit alcohol intake and quit smoking.
  • Exercise regularly as it promotes both physical and mental health.
  • Take the necessary precautions to avoid the spread of infection to other people.

Habit Forming

No

Therapeutic Class

ANTIRETROVIRAL AGENTS

Synfovir Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

Avoid drinking alcohol. Consuming alcohol while using Synfovir Tablet may worsen the condition.

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Pregnancy

Caution

Synfovir Tablet is a category B medicine. It should be used with caution in pregnant women because it may cause side effects to the unborn baby.

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Breast Feeding

Unsafe

The active part of Synfovir Tablet may pass with breast milk. Women who are HIV-positive must not breast-feed, because HIV infection can be passed on to the baby in breast milk.

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Driving

Caution

Synfovir Tablet may cause dizziness. So, avoid driving or refrain from any activities that require you to alert mentally.

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Liver

Caution

Synfovir Tablet should be used with caution in patients with liver diseases. Dose adjustments may be necessary. Patients with liver disease, who are treated with Synfovir Tablet, have a higher risk of serious and possibly fatal liver complications.

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Kidney

Unsafe

Synfovir Tablet should not be used in adolescents with kidney disease. In other people with severe kidney diseases, Synfovir Tablet is given only if clinically needed.

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Children

Unsafe

Synfovir Tablet should not be used in children below 12 years of age.

Have a query?

FAQs

Synfovir Tablet is used to treat HIV and chronic hepatitis B infection.

In the case of HIV infection, Synfovir Tablet may decrease the risk of spreading the virus to others, but the risks of infecting others still continue. Although, in the case of hepatitis B virus infection, Synfovir Tablet has not proven to decrease the risk of transferring the virus to others. Thereby, the patients of both HIV infection and hepatitis B virus (HBV) infection should not share needles and should practice safe sex.

Synfovir Tablet is safe if used in the dose and duration recommended by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's guidelines carefully and inform your doctor if any of the side effects disturb you.

Duration of treatment will depend on the seriousness of hepatitis B virus infection. You will require to take regular blood tests to keep a check on the viral load. Your doctor will then decide the duration of the Synfovir Tablet appropriately. In a few cases, treatment is needed lifelong.

Synfovir Tablet works by prevents the development of viruses in human cells. This prevents the virus from producing new viruses and cleans up your infection. It can effectively reduce the symptoms associated with HIV and chronic hepatitis B infection.

The main symptoms include yellowing of eyes and skin, flu-like symptoms, pale stools and dark-colored urine.

Synfovir Tablet does not prevent the chance of transmission of new virus infection. Therefore, always take necessary precautions as per national guidelines for the prevention of transmission of new virus infection.

If you have Tuberculosis, HIV-1 virus infection or any other medical condition, you are recommended to inform your doctor before taking Synfovir Tablet.

You should take Synfovir Tablet in the dose and duration prescribed by your doctor. Take Synfovir Tablet with or without food as advised by the doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.

If you vomit within 1 hour of taking Synfovir Tablet, take another one. However, you need not take another tablet if you vomit after more than an hour of taking Synfovir Tablet. If you experience vomiting whenever you take Synfovir Tablet or if the vomiting persists for a longer duration, consult your doctor.

If you forget to take Synfovir Tablet within 12 hours of your usual dosing time, you should take it with food as soon as possible and go back to the normal dosing schedule. If you miss a dose of Synfovir Tablet by more than 12 hours and it is almost time for your next dose, you should skip the missed dose and simply resume the regular dosing schedule.

The side effects of Synfovir Tablet include nausea, diarrhoea, rash, weakness, and stomach pain. If any of these side effects persist or worsen, please consult your doctor.

Country of origin

India
Other Info - SY84805

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jan 1, 2025 | 2:48 PM IST

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Reference

  1. https://www.drugs.com/viread.html
  2. https://www.medicines.org.uk/emc/files/pil.9932.pdf
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