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compositionComposition:AMPICILLIN-250MG+SULBACTAM-125MG
prescription
Prescription Medicine
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Synmega 250mg/125mg Tablet is used to treat bacterial infections. It contains Ampicillin and Sulbactam which work by killing infection-causing bacteria. In some cases, this medicine may cause side effects such as nausea, vomiting, headache, stomach pain and diarrhoea. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Composition :

AMPICILLIN-250MG+SULBACTAM-125MG

Manufacturer/Marketer :

Alniche Life Sciences Pvt Ltd

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Synmega 250mg/125mg Tablet

Synmega 250mg/125mg Tablet is an oral antibiotic used to treat a wide variety of bacterial infections, such as those affecting your sinuses, lungs, ears, and skin. It works by stopping the growth of harmful bacteria in your body, allowing your immune system to clear the infection. Your doctor will prescribe this medicine to help you recover safely from bacterial illnesses.

To get the best results, you must take Synmega 250mg/125mg Tablet at evenly spaced intervals and finish the entire prescription, even if you feel better after a few days. You can take this oral medication with or without food, but taking it with a light meal can help protect your stomach from irritation. Staying hydrated and getting plenty of rest during your treatment will also support your body’s recovery process.

While taking Synmega 250mg/125mg Tablet, you may experience mild side effects like nausea or diarrhoea as your body adjusts. However, if you experience severe, watery diarrhoea, a sudden skin rash, or difficulty breathing, it's important to contact your doctor right away for prompt medical evaluation. These can be signs of a more serious reaction that requires prompt medical evaluation.

Before you begin taking this medicine, tell your doctor if you have kidney disease, asthma, or a history of drug allergies. Do not take this if you have ever had a severe allergic reaction to penicillin-type antibiotics. Your healthcare provider will evaluate your medical history to make sure this is the safest option for you.

Synmega 250mg/125mg Tablet can interact with certain other substances, such as gout medications or birth control pills, which can alter how the medicine works or increase side effects. If you are pregnant, breastfeeding, or are an older adult, talk to your doctor to ensure this treatment is appropriate for your specific health needs.

Uses of Synmega 250mg/125mg Tablet

Synmega 250mg/125mg Tablet is used in the treatment of various bacterial infections. The detailed uses of Synmega 250mg/125mg Tablet are as follows:

  • Respiratory tract infections: Helps clear bacterial infections in your lungs, airways, and sinuses by stopping the bacteria from multiplying.
  • Middle ear infections: Eliminates the bacteria responsible for causing painful pressure, swelling, and fluid buildup in the ear.
  • Skin and soft tissue infections: Targets and destroys bacteria infecting the skin layers, allowing wounds and abscesses to heal cleanly.
  • Urinary tract infections: Clear bacterial growth in the urinary system to relieve painful urination and burning sensations.

Key Benefits

Synmega 250mg/125mg Tablet effectively treats bacterial infections by eliminating harmful bacteria. As the infection clears, it relieves symptoms and supports a quicker recovery. The following are the benefits of this medication:

  • Helps reduce harmful bacteria in the body and clears the infection.
  • Relieves symptoms such as fever, pain, and swelling as the infection improves.
  • Protects the antibiotic from being broken down by bacterial defence mechanisms.
  • Supports a faster and more reliable recovery.
  • Completing the full course helps prevent the infection from returning and reduces the risk of antibiotic resistance.
     

Directions for Use

  • Synmega 250mg/125mg Tablet should be taken with food.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow Synmega 250mg/125mg Tablet as a whole with a glass of water.
  • Do not crush, break, or chew it.

How Synmega 250mg/125mg Tablet Works

Synmega 250mg/125mg Tablet is a combination medicine containing two distinct active components that work together to destroy bacteria. Ampicillin: It is a penicillin-class antibiotic. Its main role is to prevent bacteria from building their outer cell walls (a tough outer layer that acts as a protective shell around the bacteria), causing them to break apart and die. This helps clear the infection and relieve symptoms. Sulbactum: Some bacteria produce defensive enzymes that can break down and destroy this antibiotic before it can work. To prevent this, sulbactam acts as a protective shield. It blocks these destructive bacterial enzymes, allowing the antibiotic to do its job safely and effectively.
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Alcohol

Caution

It is not known whether the Synmega 250mg/125mg Tablet may interact with alcohol.

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Pregnancy

Caution

Synmega 250mg/125mg Tablet should be used in pregnancy only if clinically needed and when the benefits outweigh the risks.

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Breast Feeding

Caution

Synmega 250mg/125mg Tablet may pass into breast milk in small amounts. So, it should be used with caution in breastfeeding.

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Driving

Caution

It is not known whether Synmega 250mg/125mg Tablet can affect your driving ability. Avoid driving if you experience any undesirable effects that affect your alertness.

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Liver

Caution

Synmega 250mg/125mg Tablet should be used with caution in patients with liver diseases as it may affect liver function. Your doctor may adjust the dose if required based on your condition.

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Kidney

Caution

Synmega 250mg/125mg Tablet should be used with caution in patients with kidney diseases as it may cause nephrotoxicity (damage to the kidney). Your doctor may adjust the dose if required based on your condition.

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Children

Caution

Synmega 250mg/125mg Tablet should be used in children only if clinically needed. The dose is based on the age, body weight and medical history of your child.

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Heart

Consult your doctor

Let your doctor know if you have any concerns regarding the use of Synmega 250mg/125mg Tablet in heart patients.

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Geriatrics

Caution

Synmega 250mg/125mg Tablet should be given with caution in elderly patients due to age-related side effects.

What if I have taken an overdose of Synmega 250mg/125mg Tablet

If you suspect an overdose or if someone has accidentally taken too much of this medicine, seek immediate medical attention. If the person has difficulty breathing, collapses, has a seizure, or cannot be awakened, call your local emergency medical services or contact your local poison control centre immediately.

Diet & Lifestyle Advise

  • Take probiotics: Antibiotics can disrupt the healthy bacteria in your gut. Taking a high-quality probiotic supplement or eating yoghurt with active cultures a few hours after your dose can help prevent stomach upset and diarrhoea.
  • Drink plenty of fluids: Stay well-hydrated with water throughout the day to help your kidneys process the medication safely and support your overall recovery.
  • Prioritise rest: Allow your body to focus its energy on fighting off the infection by getting adequate sleep and avoiding strenuous activity.
  • Avoid alcohol: Do not drink alcohol while recovering from an infection. Alcohol can weaken your immune system and make side effects like nausea or dizziness worse.
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How Soon It Starts Working

The time required for Synmega 250mg/125mg Tablet to start to work: Synmega 250mg/125mg Tablet ideally shows its action within 1 to 2 hours after administration. The time for which the effects of Synmega 250mg/125mg Tablet last: The duration of action for Synmega 250mg/125mg Tablet is clinically unknown.

What if you forget to take Synmega 250mg/125mg Tablet

If you miss a dose, take it as soon as you remember. If it is almost time for your next scheduled dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Storage

•Store Synmega 250mg/125mg Tablet at room temperature, ideally between 15°C and 30°C (59°F to 86°F). • Keep the medicine away from direct light, high heat, and moisture. Do not store them in the bathroom cabinet.

Drug Warnings

  • Complete the full course: Take this medicine exactly as prescribed and finish the entire course, even if you start feeling better. Stopping treatment early can allow the infection to return.
  • Check the expiry date: Always check the expiry date before taking each dose. Do not use the medicine if it has expired.
  • Watch for new infections: Contact your doctor if you notice new symptoms, such as white patches in your mouth. Antibiotics can sometimes lead to new fungal infections.
  • Report serious symptoms promptly: Contact your healthcare provider immediately if you develop a fever or severe abdominal pain during treatment or soon after it ends.
  • Tell your doctor about penicillin allergy: Inform your doctor if you have ever had a severe allergic reaction to penicillin antibiotics. You may also be at risk of reacting to some cephalosporin antibiotics.

verifiedApollotooltip
  • Gout medicines (e.g., allopurinol): Taking these medicines alongside Synmega 250mg/125mg Tablet may increase the risk of developing a skin rash.
  • Blood thinners (e.g., warfarin): Antibiotics may sometimes affect the bacteria that normally produce vitamin K in the gut, which can increase the effect of warfarin and raise the risk of bleeding. Your doctor may monitor your blood clotting levels more closely.
  • Oral contraceptives: This medicine may reduce the effectiveness of birth control pills. You should use a backup, non-hormonal barrier method (like condoms) while taking this antibiotic.
  • Immunosuppressants (e.g., methotrexate): Synmega 250mg/125mg Tablet can slow down your body's removal of methotrexate, potentially increasing the risk of serious side effects.

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verifiedApollotooltip
  • No major food interactions are established, but taking this medicine with food is highly recommended to minimise stomach upset.
     

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIBIOTIC COMBINATION]

FAQs

Synmega 250mg/125mg Tablet is used to treat bacterial infections.
Synmega 250mg/125mg Tablet contains Ampicillin and Sulbactam. Ampicillin reduces the infection by inhibiting bacterial growth. It disrupts the formation of the cell wall (outer layer), which is essential for bacteria's survival. Sulbactam inhibits the action of beta-lactamase, an enzyme produced by bacteria to destroy antibiotics (ampicillin).
You are recommended to avoid taking Synmega 250mg/125mg Tablet if you have infectious mononucleosis (viral infection with a sore throat and fever) and colitis (inflammation of the intestine), as Synmega 250mg/125mg Tablet worsens these conditions.
Synmega 250mg/125mg Tablet may decrease the effectiveness of oral contraceptives. Therefore, discuss with your doctor about other non-hormonal contraceptives such as condoms, diaphragms, etc.
No, you should not take Synmega 250mg/125mg Tablet if you have a known penicillin allergy. This medicine is a penicillin-class antibiotic and can trigger a severe allergic reaction in sensitive individuals. Talk to your doctor to find a safer alternative.
It is best to avoid alcohol while taking this medicine. While alcohol does not stop Synmega 250mg/125mg Tablet from working, it can weaken your immune system, cause dehydration, and worsen side effects like stomach upset and dizziness. Talk to your doctor if you have questions.
If you experience severe, watery, or bloody diarrhoea accompanied by stomach cramps, please contact your doctor right away for medical advice. This could be a sign of a serious antibiotic-associated bowel infection that requires prompt evaluation. Do not stop taking the antibiotic unless your doctor tells you to do so, and do not take anti-diarrhoea medicines without first speaking to your doctor.
You can take Synmega 250mg/125mg Tablet either with or without food. However, if you experience an upset stomach, nausea, or mild abdominal discomfort, taking your dose with a meal or snack can help reduce these symptoms. Talk to your doctor if stomach upset persists.
It is important to complete the full course unless your doctor advises otherwise. Stopping the antibiotic before the full course is completed can allow the strongest bacteria to survive, which can cause the infection to return and make it resistant to future treatments. If side effects make it difficult to continue treatment, please contact your doctor for advice.
This medicine should only be used during pregnancy or breastfeeding if it is clearly needed and prescribed by your healthcare provider. Some of the active ingredients can pass into breast milk in small amounts. Talk to your doctor to carefully weigh the benefits and risks for you and your baby.
Synmega 250mg/125mg Tablet is effective only against bacteria that are susceptible to it. Some bacteria, including MRSA (methicillin-resistant Staphylococcus aureus) and certain Pseudomonas species, are naturally resistant or may develop resistance to this medicine. It also does not treat viral illnesses such as colds or influenza. Your doctor may order laboratory tests to identify the bacteria causing your infection and choose the most appropriate antibiotic.

Disclaimer

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Country of origin

India
Other Info - SY14941
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