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Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Tafmune-Em Tablet is used to treat and prevent HIV (human immunodeficiency virus) infection, along with other HIV medications. It contains Emtricitabine and Tenofovir alafenamide, which works by inhibiting certain enzymes essential for the virus's replication. This medication may sometimes cause side effects such as headache, confusion, nausea, vomiting, diarrhoea, stomach pain, leg weakness, and tingling or burning sensations in the hands or feet. Inform your doctor if you have any allergies, are pregnant, breastfeeding, taking any other medications, or have any pre-existing medical conditions.

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Manufacturer/Marketer :

Cipla Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Tafmune-Em Tablet

Tafmune-Em Tablet is an antiretroviral medicine used to treat and prevent HIV (human immunodeficiency virus) infection. It helps in lowering the risk of developing AIDS (acquired immunodeficiency syndrome) and other HIV-related conditions, including cancer and severe infections. Additionally, when taken daily and combined with safe sex practices, Tafmune-Em Tablet can reduce the likelihood of contracting HIV-1. HIV weakens the immune system by destroying white blood cells essential for fighting infections. Without treatment, it can progress to incurable AIDS (Acquired Immunodeficiency Syndrome).

Tafmune-Em Tablet is a combination of two medications: Emtricitabine and Tenofovir alafenamide. Emtricitabine is a nucleoside reverse transcriptase inhibitor, while Tenofovir alafenamide is a nucleotide reverse transcriptase inhibitor. Tafmune-Em Tablet works by inhibiting the action of reverse transcriptase enzymes, which are essential for the virus to replicate. Together, these medications work to treat and prevent HIV infection.

You are advised to take Tafmune-Em Tablet for as long as your doctor has prescribed it, depending on your medical condition. In some cases, Tafmune-Em Tablet may cause common side effects such as headache, confusion, nausea, vomiting, diarrhoea, stomach pain, leg weakness, and tingling or burning sensations in the hands or feet. These side effects are usually mild and tend to improve on their own over time. However, if the side effects persist, please consult your doctor for further advice.

Before using Tafmune-Em Tablet , inform your doctor if you are allergic to any of its components or other medications. Always practice safe sex and take other necessary precautions, as Tafmune-Em Tablet does not protect against other sexually transmitted diseases. If you are pregnant or planning to become pregnant, consult your doctor before use. Tafmune-Em Tablet is not recommended for children weighing less than 25 kg. Avoid breastfeeding while using Tafmune-Em Tablet , as it may pass into breast milk. Tell your doctor if you have a history of hepatitis B, any kidney, liver, or bone issues, or if you are over 65 years old.

Uses of Tafmune-Em Tablet

Tafmune-Em Tablet is used in the treatment of HIV (human immunodeficiency virus) infection. The detailed uses of Tafmune-Em Tablet are as follows:<br/>• HIV Treatment: Tafmune-Em Tablet is used to manage HIV infection. It prevents viral replication, delays immune system damage, and reduces the risk of developing AIDS and other HIV-related conditions, such as cancer and severe infections.<br/>• Pre-Exposure Prophylaxis (PrEP): Tafmune-Em Tablet can also be used as Pre-Exposure Prophylaxis (PrEP) to reduce the risk of HIV-1 infection in individuals who are at high risk of exposure but are not yet infected.<br/>

Directions for Use

• Tafmune-Em Tablet can be taken with meals to avoid stomach upset.• Take Tafmune-Em Tablet once daily or as advised by your doctor.• Swallow the whole tablet with a glass of water.• Do not break, chew, or crush it.

Medicinal Benefits

Tafmune-Em Tablet belongs to a group of medications called 'antiretrovirals,' which are used to treat and prevent HIV infection. It helps lower the risk of developing AIDS (acquired immunodeficiency syndrome) and other HIV-related conditions, such as cancer and severe infections. Tafmune-Em Tablet contains two active ingredients: Emtricitabine and Tenofovir alafenamide. Emtricitabine is a nucleoside reverse transcriptase inhibitor, while Tenofovir alafenamide is a nucleotide reverse transcriptase inhibitor. These medications block the reverse transcriptase enzymes' function, essential for replicating the virus. Together, these medications help manage HIV infection. Additionally, when taken daily and combined with safe sex practices, Tafmune-Em Tablet can reduce the likelihood of contracting HIV-1.

How Tafmune-Em Tablet Works

Tafmune-Em Tablet is a combination of two medications: Emtricitabine and Tenofovir alafenamide. Emtricitabine is a nucleoside reverse transcriptase inhibitor, while Tenofovir alafenamide is a nucleotide reverse transcriptase inhibitor. Tafmune-Em Tablet works by inhibiting the action of reverse transcriptase enzymes, which are essential for virus replication. Together, these medications work to treat and prevent HIV infection.

Storage

• Store in a cool and dry place away from sunlight.• Keep it out of the sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Tafmune-Em Tablet

Take Tafmune-Em Tablet exactly as prescribed by your doctor. Do not exceed the recommended dose, as doing so may lead to an overdose. If you suspect you have taken too much of this medicine, seek medical attention from a doctor or a nearby hospital.

Drug Warnings

Do not use Tafmune-Em Tablet if you are allergic to any of its components. Always practice safe sex and take other necessary precautions, as Tafmune-Em Tablet does not protect against other sexually transmitted diseases. While using Tafmune-Em Tablet , it is important to have regular blood and urine tests. If you experience any symptoms of infection or inflammation, contact your doctor immediately. If you are pregnant or planning to become pregnant, consult your doctor before using Tafmune-Em Tablet , as it is not known how this medication may affect the unborn child or pregnancy. Tafmune-Em Tablet is not recommended for children weighing less than 25 kg. Avoid breastfeeding while using Tafmune-Em Tablet , as it may pass into breast milk. Additionally, inform your doctor if you have a history of hepatitis B, any kidney, liver, or bone issues, or if you are over 65 years old. A regular bone density test is advised while taking Tafmune-Em Tablet , as it may cause bone problems such as soft, thin bones and bone pain.

Drug-Drug Interactions

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EmtricitabineLamivudine
Critical

Drug-Drug Interactions

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EmtricitabineLamivudine
Critical
How does the drug interact with Tafmune-EM Tablet:
Combining these two medications may reduce overall effectiveness due to potential antagonistic effects (opposite actions).

How to manage the interaction:
Taking Tafmune-EM Tablet with Lamivudine is not recommended, but it can be taken if your doctor prescribes it. Contact your doctor if your symptoms do not improve. Do not stop taking any medication without consulting your doctor.
How does the drug interact with Tafmune-EM Tablet:
Coadministration of Cidofovir and Tafmune-EM Tablet can increase the risk of kidney problems.

How to manage the interaction:
Taking Cidofovir and Tafmune-EM Tablet together is not recommended as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Tafmune-EM Tablet:
The combined use of Mefenamic acid and Tafmune-EM Tablet can increase the risk of kidney problems.

How to manage the interaction:
Taking Mefenamic acid and Tafmune-EM Tablet together can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Tafmune-EM Tablet:
Coadministration of Naproxen and Tafmune-EM Tablet may increase the effectiveness of Tafmune-EM Tablet.

How to manage the interaction:
There may be a possible interaction between Naproxen and Tafmune-EM Tablet, but they can be taken together if they are prescribed by doctor. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, consult the doctor. Do not discontinue any medication without a doctor's advice.
How does the drug interact with Tafmune-EM Tablet:
Combining Tafmune-EM Tablet with Modafinil may significantly reduce the blood levels of Tafmune-EM Tablet.

How to manage the interaction:
There may be a possibility of interaction between Tafmune-EM Tablet and Modafinil, but it can be taken if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Tafmune-EM Tablet:
Taking leflunomide with Tafmune-EM Tablet can increase the risk of liver problems.

How to manage the interaction:
Taking Leflunomide and Tafmune-EM Tablet together can lead to an interaction, it can be taken if advised by your doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Tafmune-EM Tablet:
Co-administration of Tafmune-EM Tablet with valacyclovir may increase the risk of kidney problems.

How to manage the interaction:
Although taking Tafmune-EM Tablet and valacyclovir together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as nausea, vomiting, loss of appetite, increased urination, weight loss, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without consulting a doctor.
Severe
How does the drug interact with Tafmune-EM Tablet:
The combined use of Voclosporin and Tafmune-EM Tablet can increase the risk of kidney problems.

How to manage the interaction:
Taking Voclosporin and Tafmune-EM Tablet together can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Tafmune-EM Tablet:
The combined use of Cisplatin and Tafmune-EM Tablet can increase the risk of kidney problems.

How to manage the interaction:
Taking Cisplatin and Tafmune-EM Tablet together can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Tafmune-EM Tablet:
Co-administration of diclofenac and Tafmune-EM Tablet may cause kidney problems.

How to manage the interaction:
There may be a possible interaction between Diclofenac and Tafmune-EM Tablet but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience symptoms such as such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy and well-rounded diet, focusing on nutrient-dense foods like fruits and vegetables to strengthen your immune system. For optimal health, choose lean protein sources and whole grains.
  • Ensure that meat is fully cooked, drink clean, safe water, and avoid consuming raw eggs, seafood, and unpasteurized dairy products.
  • Stay up to date on vaccinations such as those for pneumonia, flu, and COVID-19, and consult your doctor about any additional vaccines you may need. Avoid vaccines that contain live viruses.
  • Remember to wash your hands after handling pets or cleaning litter boxes to prevent infections.
  • Practice safe sex by using condoms to minimize exposure to semen and vaginal fluids.
  • Do not share personal items, such as razors or toothbrushes that may have come into contact with body fluids or blood.

Habit Forming

No

Therapeutic Class

ANTIRETROVIRAL AGENTS

Tafmune-Em Tablet Substitute

Substitutes safety advice
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Alcohol

Caution

It is not known whether alcohol interacts with Tafmune-Em Tablet . Please consult your doctor.

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Pregnancy

Consult your doctor

Please consult your doctor if you are pregnant, as it is not known how Tafmune-Em Tablet may affect the unborn child or pregnancy. Your doctor will prescribe Tafmune-Em Tablet only if the benefits outweigh the potential risks.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Tafmune-Em Tablet , as it may pass into breast milk.

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Driving

Caution

Tafmune-Em Tablet may cause dizziness. So, avoid driving or operating machinery until you are fully alert.

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Liver

Caution

Please consult your doctor before taking Tafmune-Em Tablet if you have a liver disease or any concerns regarding this.

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Kidney

Caution

Please consult your doctor before taking Tafmune-Em Tablet if you have kidney disease or any concerns regarding this.

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Children

Consult your doctor

Tafmune-Em Tablet is not recommended for children weighing less than 25 kg. Please consult your doctor if you have any concerns about the safety of Tafmune-Em Tablet in this age group.

Have a query?

FAQs

Tafmune-Em Tablet is an antiretroviral medicine used to treat and prevent HIV (human immunodeficiency virus) infection. It helps lower the risk of developing AIDS (acquired immunodeficiency syndrome) and other HIV-related conditions, including cancer and severe infections. Additionally, when taken daily and combined with safe sex practices, Tafmune-Em Tablet can reduce the likelihood of contracting HIV-1.

Tafmune-Em Tablet is a combination of two medications: Emtricitabine and Tenofovir alafenamide. Emtricitabine is a nucleoside reverse transcriptase inhibitor, while Tenofovir alafenamide is a nucleotide reverse transcriptase inhibitor. Tafmune-Em Tablet works by inhibiting the action of reverse transcriptase enzymes, which are essential for the virus to replicate. Together, these medications work to treat and prevent HIV infection.

The common side effects of Tafmune-Em Tablet include headache, confusion, nausea, vomiting, diarrhoea, stomach pain, leg weakness, and tingling or burning sensations in the hands or feet. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

HIV-negative patients can take Tafmune-Em Tablet to lower the chance of getting an HIV infection if prescribed by a doctor. Before starting the treatment, you should have a negative HIV test. While taking Tafmune-Em Tablet , regular HIV tests (at least every 3 months) are advised.

Tafmune-Em Tablet may cause lactic acidosis (an excess of lactic acid in the blood), a rare but severe side effect, especially in women who are obese and people with liver disease. Please consult a doctor immediately if you experience stomach pain, vomiting, nausea, drowsiness, or deep, rapid breathing while taking Tafmune-Em Tablet .

Tafmune-Em Tablet does not cure HIV infection. However, Tafmune-Em Tablet helps lower the risk of developing AIDS (acquired immunodeficiency syndrome) and other HIV-related conditions, including cancer and severe infections.

Tafmune-Em Tablet may cause bone problems, such as soft bones, thin bones, and bone pain. Regular bone density tests are advised while taking Tafmune-Em Tablet . For good bone health, take calcium and vitamin D supplements as advised by your doctor.

If you forget to take a dose of Tafmune-Em Tablet , take it as soon as you remember unless it is almost time for your next dose. In that case, skip the missed dose and continue your regular schedule. Missing doses can reduce the effectiveness of this medication and may lead to the development of drug resistance, raising the risk of acquiring HIV.

Do not stop taking Tafmune-Em Tablet without consulting your doctor, as it may reduce the effectiveness of the medication. Continue taking Tafmune-Em Tablet for the duration prescribed by your doctor.

Country of origin

India

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Other Info - TAF0015

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