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  3. Taxelap Injection

Taxelap Injection, Pack of 1 Injection
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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Taxelap Injection is used to prevent nausea and vomiting during chemotherapy. It contains Palonosetron, which blocks the action of serotonin, a chemical that stimulates the vomiting centre (chemoreceptor trigger zone) located in the brain. Thus, it prevents nausea and vomiting. Common side effects of Taxelap Injection are diarrhoea, constipation, dizziness or headache.
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Composition :

PALONOSETRON-0.25MG/ML

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

About Taxelap Injection

Taxelap Injection belongs to a class of drugs called antiemetics used to prevent nausea and vomiting during chemotherapy. Nausea is a feeling of uneasiness of the stomach that often comes before vomiting. On the other hand, vomiting is the forcible voluntary or involuntary emptying of stomach contents through the mouth.

Taxelap Injection contains Palonosetron which works by blocking the action of serotonin, a chemical that stimulates the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, it prevents nausea and vomiting.

Taxelap Injection will be administered by a healthcare professional; do not self-administer. In some cases, you may experience diarrhoea, constipation, dizziness or headache. Most of these side effects of Taxelap Injection do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Taxelap Injection or any other medicines, please tell your doctor. Taxelap Injection may be given to children above 1 month in doses as advised by a doctor based on the child's body weight. If you are pregnant or breastfeeding, please inform your doctor before taking Taxelap Injection. Drive only if you are alert as Taxelap Injection may cause tiredness or dizziness. You are recommended to avoid heavy meals and take small nourishing snacks throughout the day. Drink plenty of water to avoid dehydration.

Uses of Taxelap Injection

Taxelap Injection is used in the treatment of Nausea and vomiting. The detailed uses of Taxelap Injection are as follows:<br/>• Chemotherapy-Induced Nausea and Vomiting (CINV): Taxelap Injection prevents acute and delayed CINV, providing long-lasting relief and improving patient quality of life during chemotherapy.<br/>• Postoperative Nausea and Vomiting (PONV): Taxelap Injection prevents PONV, reducing patient discomfort and promoting smoother recovery after surgery.<br/>

Directions for Use

• Taxelap Injection is administered only in clinical settings by healthcare professionals, usually through intravenous or intramuscular injections.• The dosage and timing are decided by the doctor, depending on the cause and severity of symptoms.• Do not self-administer this medication.• Patients are monitored during and after administration to ensure safety and effective control of symptoms.

Medicinal Benefits

Taxelap Injection contains Palonosetron which blocks the action of serotonin, a chemical that stimulates the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, it prevents nausea and vomiting during chemotherapy.

How Taxelap Injection Works

Taxelap Injection contains Palonosetron which works by blocking the action of serotonin, a chemical that stimulates the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, it prevents nausea and vomiting.

Storage

• Store in a cool and dry place away from sunlight.• Keep Taxelap Injection out of reach and sight of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Taxelap Injection

As Taxelap Injection is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. However, if you think there has been an overdose or experiencing any adverse events, get medical care right away. Overdose of Taxelap Injection may cause bluish colour of the fingernails, lips, skin, palms, or nail beds, collapse, gasping to breathe, paleness of the skin, and seizures.

Drug Warnings

If you are allergic to Taxelap Injection or any other medicines, please tell your doctor. Taxelap Injection may be given to children above 1 month in doses as advised by a doctor based on the child's body weight. If you are pregnant or breastfeeding, please inform your doctor before taking Taxelap Injection. Drive only if you are alert as Taxelap Injection may cause tiredness or dizziness. You are recommended to avoid heavy meals and take small nourishing snacks throughout the day. Drink plenty of water to avoid dehydration.

Diet & Lifestyle Advise

  • Eat a healthy diet and a low-fat diet, especially in small portions, as it will be easy for digestion. Avoid eating over-sweet food and include more salty food, especially if you have been vomiting.
  • Also, if you like to vomit at a specific time, avoid eating your favourite food at that particular time as your taste for that food may get turned off.
  • Drink any other liquid at least 30 minutes after eating food.
  • If the smell of food makes you feel sick (vomit), do not cook food as it may worsen your condition. Let someone else do the cooking or use prepared food from the freezer.

Habit Forming

No

Therapeutic Class

ANTIEMETICS
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Alcohol

Caution

The interaction of alcohol with Taxelap Injection is unknown. Please consult a doctor before consuming alcohol with Taxelap Injection.

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Pregnancy

Consult your doctor

Taxelap Injection is given to pregnant women only if the doctor thinks the benefits outweigh the risks. Please inform your doctor if you are pregnant.

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Breast Feeding

Consult your doctor

Please inform your doctor before taking Taxelap Injection if you are breastfeeding. Taxelap Injection is given to breastfeeding women only if the doctor thinks the benefits are greater than the risks.

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Driving

Caution

Taxelap Injection may cause tiredness or dizziness in some people. Therefore, avoid driving or operating heavy machinery if you feel tired or dizzy after taking Taxelap Injection.

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Liver

Safe if prescribed

Taxelap Injection may be safe to use in patients with liver problems if prescribed by a doctor. However, if you have any concerns regarding this, please discuss them with your doctor.

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Kidney

Safe if prescribed

Taxelap Injection may be safe to use in patients with kidney problems if prescribed by a doctor. However, if you have any concerns regarding this, please discuss them with your doctor.

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Children

Caution

Taxelap Injection may be given to children above 1 month in doses as advised by a doctor based on the child's body weight.

Have a query?

FAQs

Taxelap Injection is used to treat nausea and vomiting.

Taxelap Injection contains Palonosetron which works by blocking the action of serotonin, a chemical that stimulates the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, it prevents nausea and vomiting.

You are not recommended to take erythromycin with Taxelap Injection as it may increase the risk of severe irregular heart rhythm. However, please consult your doctor before taking other medicines with Taxelap Injection.

Taxelap Injection may cause constipation as a side effect. It is not necessary for everyone taking Taxelap Injection to experience this side effect. However, if the condition persists or worsens, please consult a doctor.

Taxelap Injection should be used with caution in patients suffering from heart problems as it may worsen the condition. Therefore, inform your doctor if you have any heart problems before taking have Taxelap Injection so that the dose may be adjusted appropriately.

Country of origin

India
Other Info - TA54585

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 7:02 AM IST

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Reference

  1. https://www.medicines.org.uk/emc/files/pil.513.pdf
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