Tazotum 4.5mg Injection
PIPERACILLIN-4000MG + TAZOBACTAM-500MG
Tazotum 4.5mg Injection
Tazotum 4.5mg Injection belongs to the 'Antibiotics' class of drugs, primarily used to treat bacterial infections. It is used to treat various hospital-acquired and ventilator-associated pneumonia, urinary tract infections, intra-abdominal infections, skin and soft tissue infections (like diabetic foot infections) and uterine infections. Bacterial infection occurs when harmful bacteria grow in the body and causes illness. It can infect any part of the body and multiply very quickly.
Tazotum 4.5mg Injection contains two medicines, namely: Piperacillin (Penicillin antibiotic) and Tazobactam (beta-lactamase inhibitor). Piperacillin belongs to the class of 'Penicillin antibiotics.' It has bactericidal (ability to kill bacteria) activity against gram-positive and gram-negative aerobic (requires oxygen to survive) and anaerobic (survives with little or no oxygen) bacteria. Piperacillin acts by binding to the penicillin-binding proteins (PBPs) inside the bacterial cell wall and inhibits its cell wall synthesis. Tazobactam is a beta-lactamase inhibitor. Beta-lactamases are the enzymes produced by bacteria to gain multi-resistance to β-lactam antibiotics, such as penicillins and cephalosporins. Tazobactam prevents the breakdown of other antibiotics by beta-lactamase enzyme producing organisms. In Tazotum 4.5mg Injection, Tazobactam works by preventing bacteria from destroying Piperacillin.
Tazotum 4.5mg Injection is available in the form of intravenous injection. Like all medicines, Tazotum 4.5mg Injection also causes side effects, although not everybody gets them. Common side effects of Tazotum 4.5mg Injection include nausea, constipation, diarrhoea, headache, and trouble sleeping. If any of these effects persist or worsen, seek medical advice promptly.
Brief your medical history to the doctor if you have any allergic reactions to antibiotics. Please inform your doctor if you have any liver, kidney diseases, bleeding disorders, and fits. Do not use Tazotum 4.5mg Injection while having vaccinations with live bacterial vaccines (typhoid vaccine) since Tazotum 4.5mg Injection may affect vaccines' activity. Tazotum 4.5mg Injection should be used during pregnancy only if the doctor advised you. It is also excreted into breast milk in small amounts. Hence, it is recommended to consult your doctor if you are pregnant or breastfeeding before taking Tazotum 4.5mg Injection.
Bacterial infections, hospital-acquired and ventilator-associated pneumonia, urinary tract infections, intra-abdominal infections, skin and soft tissue infections, and uterine infections.
Store in a cool and dry place away from sunlight
If you have a history of any cystic fibrosis (damaged lungs and digestive system), kidney disease, fits, colitis (inflammation of the colon), bleeding disorders, heart or liver diseases, please inform your doctor before starting Tazotum 4.5mg Injection. Please tell your doctor if you are undergoing dialysis treatment since Penicillin antibiotics like Piperacillin are removed by haemodialysis. Your doctor may schedule the dosage after dialysis. Clostridium difficile associated diarrhoea (CDAD) is reported during usage of antibiotics like Tazotum 4.5mg Injection. Therefore, please undergo an examination to rule out the chances of CDAD if you experience diarrhoea following Tazotum 4.5mg Injection therapy.
Let your doctor know if you are undergoing any vaccinations with live bacterial vaccines (like typhoid vaccine) since Tazotum 4.5mg Injection may affect vaccines' activity. Tazotum 4.5mg Injection should be used with caution during pregnancy since it crosses the placenta in humans. Tazotum 4.5mg Injection is also excreted into breast milk. Please seek medical advice if you are pregnant or breastfeeding before taking Tazotum 4.5mg Injection. Patients aged above 65 years are not at an increased risk of having side effects. However, the dosage should be adjusted if the patient has a history of renal impairment. Sometimes, antibiotic medications can cause antibiotic resistance. In such cases, your doctor may prescribe other antibiotics, you are not resistant.
Avoid alcohol consumption while taking Tazotum 4.5mg Injection to prevent unpleasant side-effects, such as nausea and vomiting.
Tazotum 4.5mg Injection should be used with caution during pregnancy since it crosses the placenta in humans. Please consult your doctor before taking Tazotum 4.5mg Injection if you are pregnant or planning to conceive.
There is limited data on how Tazotum 4.5mg Injection affects breastfed infants. Tazotum 4.5mg Injection is excreted into breast milk. Please consult your doctor before taking Tazotum 4.5mg Injection if you are breastfeeding.
It is unknown whether Tazotum 4.5mg Injection affects your ability to drive and operating machinery. Drive only if you are physically stable and mentally focussed. If you experience dizziness or fatigue after taking Tazotum 4.5mg Injection, do not drive or operate any machinery.
Let your doctor know if you have any history of liver diseases before taking Tazotum 4.5mg Injection. Your doctor will prescribe Tazotum 4.5mg Injection only if the benefits outweigh the risk.
Penicillin antibiotics are easily removed by dialysis. Beta-lactam antibiotics like Tazobactam should be cautiously administered in patients with renal impairment. Prolonged use of Tazotum 4.5mg Injection may cause nephrotoxicity and alterations in renal function, hence please let your doctor know if you have any history of kidney diseases before taking Tazotum 4.5mg Injection. Your doctor will prescribe Tazotum 4.5mg Injection only if the benefits outweigh the risk.
This item is Not Returnable.
Expires on or after - October 2021
Tazotum 4.5mg Injection contains Piperacillin and Tazobactam. Piperacillin inhibits bacterial cell wall synthesis, and Tazobactam prevents the bacteria from gaining resistance against Piperacillin. Thus Tazotum 4.5mg Injection helps in treating various bacterial infections.
Tazotum 4.5mg Injection should be used with proper caution and doctor consultation if you have any cystic fibrosis (damaged lungs and digestive system), kidney disease, fits, colitis (inflammation of the colon), bleeding disorders, heart or liver diseases and undergoing dialysis.
Tazotum 4.5mg Injection can affect live vaccines like typhoid vaccine and decrease their effectiveness. Please consult a doctor before you start Tazotum 4.5mg Injection if you are undergoing any vaccinations.
It is recommended to complete the course of Tazotum 4.5mg Injection even if you feel better as it is an antibiotic, and stopping it midway may lead to recurring infections. Continue taking Tazotum 4.5mg Injection for as long as your doctor has prescribed to treat your condition effectually.
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