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compositionComposition:TENECTEPLASE-30MG
prescriptionPrescription Medicine
Tenepact 30 Injection Kit

Tenepact 30 Injection Kit is a clot-busting drug indicated to reduce the risk of death in people who have had a severe type of heart attack known as acute ST-elevation myocardial infarction (STEMI). It contains Tenecteplase, which helps to dissolve unwanted blood clots in the heart's blood vessels. Thus, it helps to prevent damage caused by heart attacks and has been shown to save lives.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

TENECTEPLASE-30MG

Manufacturer/Marketer :

Glenmark Pharmaceuticals Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

Tenepact 30 Injection Kit belongs to the class of drugs called thrombolytics (clot-busting drugs) indicated to reduce the risk of death in people who have had a serious type of heart attack known as acute ST-elevation myocardial infarction (STEMI). Heart attack refers to blocked blood flow to the heart due to blockage of arteries. STEMI is a type of serious heart attack that mainly affects the lower chambers of the heart.

Tenepact 30 Injection Kit contains Tenecteplase, a clot-busting drug that helps to dissolve unwanted blood clots in the blood vessels of the heart. Thus, it helps to prevent damage caused by heart attack.

Tenepact 30 Injection Kit will be administered by a healthcare professional; do not self-administer. Tenepact 30 Injection Kit may cause common side effects such as bleeding, nosebleeds, bruising, bleeding at the injection or puncture site, or blood in the urine. If you notice such side effects, please inform your doctor.

If you are allergic to Tenecteplase or any other medicines, please tell your doctor. Tenepact 30 Injection Kit should be used with caution in patients aged over 75 years and who weigh less than 60 kg. Tenepact 30 Injection Kit is not recommended for children below 18 years of age as the safety and effectiveness were not established. If you are a pregnant or breastfeeding woman, please inform your doctor before receiving Tenepact 30 Injection Kit. If you have had a recent major surgery or trauma, inform your doctor. 

Uses of Tenepact 30 Injection Kit

Tenepact 30 Injection Kit is used in the treatment of Acute myocardial infarction (Heart attack). The detailed use of Tenepact 30 Injection Kit is as follows:

  • Treatment of Acute Myocardial Infarction: Tenepact 30 Injection Kit is used for the treatment of acute myocardial infarction (heart attack) by dissolving blood clots in the coronary arteries, restoring blood flow to the heart muscle, and minimizing damage during a heart attack.

Key Benefits

Tenepact 30 Injection Kit contains Tenecteplase, a clot-busting drug indicated to reduce the risk of death in people who have had a serious type of heart attack known as acute ST-elevation myocardial infarction (STEMI). It helps to dissolve unwanted blood clots in the blood vessels of the heart. Thus, it helps to prevent damage caused by heart attack and has been shown to save lives.

Side effects of Tenepact 30 Injection Kit
Managing Medication-Triggered Epistaxis (Nosebleed): A Step-by-Step Guide:
  • If you experience nosebleeds or unusual bleeding after taking medication, seek medical attention right away and schedule an appointment to discuss your symptoms with your doctor.
  • Your doctor may adjust your treatment plan by changing the dosage, switching to a different medication, or stopping the medication.
  • If your doctor advises, take steps to manage bleeding and promote healing, such as applying pressure, using saline nasal sprays, or applying a cold compress, using humidifiers, avoiding blowing or picking your nose, and applying petroleum jelly to the nostrils.
  • Schedule follow-up appointments with your doctor to monitor progress, adjust treatment plans, and prevent future episodes.
  • Stay hydrated to support kidney and bladder health.
  • Rest on your back as advised by your doctor.
  • Limit physical strain for 1-2 weeks.
  • Avoid strenuous activities like running and contact sports.
  • Quit smoking to improve overall health.
  • Use pain medication responsibly.
  • Avoid foods that can irritate the urinary track, such as spicy or acidic foods.
  • Remember to consult your doctor for personalized advice and guidance on managing your symptoms and developing a treatment plan.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safe and effective use.
  • Tenepact 30 Injection Kit will be administered by the doctor or healthcare professional in a medical setting.
  • Do not self-administer.
Tenepact 30 Injection Kit contains Tenecteplase, a clot-busting drug that helps to dissolve unwanted blood clots in the blood vessels of the heart. Thus, it helps to prevent damage caused by heart attack.
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Alcohol

Not applicable

Tenepact 30 Injection Kit is administered to hospitalized patients.

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Pregnancy

Consult your doctor

Limited data is available on the effect of Tenepact 30 Injection Kit in pregnant women. If you are pregnant or planning pregnancy, inform your doctor before receiving Tenepact 30 Injection Kit. Your doctor may give this medicine if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

It is unknown whether Tenecteplase is excreted in breast milk. Hence, if you are a nursing mother, inform your doctor before receiving Tenepact 30 Injection Kit. Your doctor may give this medicine if the benefits outweigh the risks.

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Driving

Not applicable

Tenepact 30 Injection Kit is administered to hospitalized patients.

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Liver

Consult your doctor

The effect of liver impairment on the actions of Tenepact 30 Injection Kit in humans has not been particularly studied. However, if you have severe liver failure, inform your doctor before receiving Tenepact 30 Injection Kit.

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Kidney

Consult your doctor

The effect of kidney impairment on the actions of Tenepact 30 Injection Kit in humans has not been particularly studied. However, if you have severe kidney problems, inform your doctor before receiving Tenepact 30 Injection Kit.

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Children

Unsafe

Tenepact 30 Injection Kit is not recommended for children below 18 years of age as the safety and effectiveness were not established.

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Heart

Safe if prescribed

Tenepact 30 Injection Kit is used to treat certain heart attacks by dissolving clots and restoring blood flow. However, it should be avoided in patients with heart problems unless absolutely necessary and under strict medical supervision.

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Geriatrics

Caution

Tenepact 30 Injection Kit may be used in geriatric patients for treating certain heart attacks, but only under strict medical supervision. Due to increased bleeding risks and age-related health concerns, careful assessment and monitoring are essential.

Since Tenepact 30 Injection Kit is given in a controlled medical setting by a healthcare professional, an overdose is not likely to occur. If you think there has been an overdose or experiencing any adverse events, get medical care right away. In a medical setting, an overdose would be treated quickly.

Diet & Lifestyle Advise

  • Maintain a diet consisting of vegetables, whole grains, fruits and lean protein.
  • Reduce sugar and processed foods.
  • Include foods high in antioxidants, such as vegetables, fruits, olive oil, seeds, nuts, cocoa, and red wine, as they may lower the risk of developing blood clots.
  • Adopt an anti-inflammatory diet high in omega-3-rich foods, fruits and vegetables, and vitamin-E-rich foods.
  • Drink plenty of fluids as dehydration can thicken blood leading to an increased risk of blood clot formation.
  • Do regular exercise as it helps to dissolve blood clots, especially in obese people.
  • Quit smoking and also avoid being around secondhand smoke.

Have a query?

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Keep Refrigerated. Do not freeze.

Drug Warnings

If you are allergic to Tenecteplase or any other medicines, please tell your doctor. Tenepact 30 Injection Kit should be used with caution in patients aged over 75 years of age and who weigh less than 60 kg. Tenepact 30 Injection Kit is not recommended for children below 18 years of age as the safety and effectiveness were not established. If you are a pregnant or breastfeeding woman, please inform your doctor before receiving Tenepact 30 Injection Kit. If you have had a recent major surgery or trauma, inform your doctor. Tenepact 30 Injection Kit is not recommended if you have been given cardiopulmonary resuscitation (chest compressions) for more than 2 minutes duration in the last two weeks. You are advised to be careful while using sharp objects, cutting nails, or shaving, as Tenepact 30 Injection Kit may increase the risk of bleeding. 

Drug-Drug Interactions

verifiedApollotooltip
TenecteplaseHeparin
Critical
TenecteplaseDabigatran etexilate
Severe

Drug-Drug Interactions

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TenecteplaseHeparin
Critical
How does the drug interact with Tenepact 30 Injection Kit:
Taking Tenepact 30 Injection Kit with Heparin can increase the risk of bleeding.

How to manage the interaction:
Taking Heparin with Tenepact 30 Injection Kit is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you notice unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
TenecteplaseDabigatran etexilate
Severe
How does the drug interact with Tenepact 30 Injection Kit:
Taking Dabigatran etexilate with Tenepact 30 Injection Kit can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Dabigatran etexilate with Tenepact 30 Injection Kit together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
TenecteplaseDeferasirox
Severe
How does the drug interact with Tenepact 30 Injection Kit:
Combining Tenepact 30 Injection Kit with Deferasirox can increase the risk of gastrointestinal bleeding.

How to manage the interaction:
Co-administration of Tenepact 30 Injection Kit with Deferasirox can possibly result in an interaction, but it can be taken if your doctor has advised it. This risk is higher in older people with certain blood disorders or low platelet counts.If you have symptoms like stomach pain, bloating, dizziness, or black stools, it's important to consult a doctor. Do not stop using any medications without a doctor's advice.
TenecteplaseEnoxaparin
Severe
How does the drug interact with Tenepact 30 Injection Kit:
Combining Tenepact 30 Injection Kit with Enoxaparin can increase the risk of bleeding.

How to manage the interaction:
Co-administration of Tenepact 30 Injection Kit with Enoxaparin can result in an interaction, but it can be taken if your doctor has advised it. You should seek immediate medical attention if you experience any unusual bleeding or bruising or have other signs and symptoms of bleeding such as dizziness; lightheadedness; red or black, tarry stools; coughing up or vomiting fresh or dried blood that looks like coffee grounds; severe headache; and weakness. Using more than one of these medications can increase the risk of bleeding even more, but it may not give you much extra protection. Do not discontinue any medications without consulting a doctor.
TenecteplaseFondaparinux
Severe
How does the drug interact with Tenepact 30 Injection Kit:
Taking Tenepact 30 Injection Kit with fondaparinux can increase the risk of bleeding.

How to manage the interaction:
Taking Tenepact 30 Injection Kit with Fondaparinux together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience bleeding, severe back pain, dizziness, black or red stools, severe headache, weakness, and vomiting contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
TenecteplaseDasatinib
Severe
How does the drug interact with Tenepact 30 Injection Kit:
Taking Dasatinib with Tenepact 30 Injection Kit can increase the risk and severity of bleeding and hemorrhage.

How to manage the interaction:
Although taking Tenepact 30 Injection Kit and Dasatinib together can cause an interaction, it can be taken if a doctor has suggested it. You should seek immediate medical attention if you experience dizziness; red or black, tarry stools; severe headache; and weakness. Do not discontinue any medications without consulting a doctor.
TenecteplaseCangrelor
Severe
How does the drug interact with Tenepact 30 Injection Kit:
Co-administration of Cangrelor with Tenepact 30 Injection Kit can increase the risk of bleeding.

How to manage the interaction:
Although taking Tenepact 30 Injection Kit and Cangrelor together can evidently cause an interaction, it can be taken if a doctor has suggested it. However, consult doctor immediately if you experience any unusual bleeding or bruising, or have other signs and symptoms of bleeding such as dizziness; lightheadedness; red or black, tarry stools; coughing up or vomiting fresh or dried blood that looks like coffee grounds; severe headache; and weakness. Do not stop using any medications without a doctor's advice.
TenecteplaseWarfarin
Severe
How does the drug interact with Tenepact 30 Injection Kit:
Coadministration of warfarin with Tenepact 30 Injection Kit can increase the risk of bleeding.

How to manage the interaction:
Although taking Tenepact 30 Injection Kit and warfarin together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
TenecteplasePrasugrel
Severe
How does the drug interact with Tenepact 30 Injection Kit:
Taking Prasugrel with Tenepact 30 Injection Kit can increase the risk of bleeding.

How to manage the interaction:
Taking Tenepact 30 Injection Kit with Prasugrel together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
TenecteplaseIbrutinib
Severe
How does the drug interact with Tenepact 30 Injection Kit:
Co-administration of Ibrutinib with Tenepact 30 Injection Kit can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Ibrutinib with Tenepact 30 Injection Kit together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

No
[THROMBOLYTIC ENZYME]

FAQs

Tenepact 30 Injection Kit is used to treat Acute myocardial infarction (Heart attack).

Tenepact 30 Injection Kit contains Tenecteplase, a clot-busting drug that dissolves unwanted blood clots in the blood vessels of the heart. Thus, it helps to prevent damage caused by heart attack.

You are recommended to consult a doctor before taking warfarin while on treatment with Tenepact 30 Injection Kit as it may increase the risk of bleeding more easily. Your doctor may advise dose adjustment. Therefore, please consult a doctor before taking other medicines with Tenepact 30 Injection Kit.

Tenepact 30 Injection Kit may increase the risk of bleeding. Therefore, you are advised to be careful while using sharp objects, cutting nails, or shaving.

Tenepact 30 Injection Kit should be administered through the intravenous (IV) route only. It should be administered by the doctor or nurse. Do not self-administer.

Avoid receiving Tenepact 30 Injection Kit with blood thinners such as heparin, ticlopidine, clopidogrel, and vitamin K antagonists as it may increase the risk of bleeding. However, it is best to avoid self-medicating or taking new drugs without consulting the doctor to ensure safety.

After receiving Tenepact 30 Injection Kit, you may feel better as it starts working to dissolve blood clots and improve blood flow. However, the exact timing varies depending on your medical condition and response to treatment. For some individuals, improvements may be noticeable within hours, while others might take longer. Therefore, always follow up with your doctor to monitor your condition and evaluate your progress.

The side effects of Tenepact 30 Injection Kit include bruising, such as bleeding, nosebleeds, bleeding at the injection or puncture site, or blood in the urine. If you experience any of these symptoms, consult the doctor immediately.

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Author Details

Veda MaddalaDoctor badge

Written By

  • Veda Maddala

    M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

  • Dr Aneela Siddabathuni

    MPharma., PhD

Last Updated

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India
Glenmark Pharmaceuticals Limited, B/2, Mahalaxmi Chambers, 22, Bhulabhai Desai Road, Mumbai €“ 400 026.
Other Info - TEN0786

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