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compositionComposition:TENOFOVIR ALAFENAMIDE-25MG
prescription
Prescription Medicine
info
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Tenfoliv-AF Tablet is used to treat chronic hepatitis B virus (HBV) infection. It contains Tenofovir alafenamide which works by inhibiting HBV replication and clears the infection. In some cases, this medicine may cause side effects like headaches, diarrhoea, nausea, vomiting, and rash. Keep the doctor informed about your health condition and the medications you are taking.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
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More about the Product

Composition :

TENOFOVIR ALAFENAMIDE-25MG

Manufacturer/Marketer :

Transcure Therapeutics Pvt Ltd

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Tenfoliv-AF Tablet

Tenfoliv-AF Tablet is a prescription medication used to treat long-term (chronic) hepatitis B virus infection in adults and adolescents. It helps manage the virus, preventing it from multiplying and causing severe liver problems. This medication is essential for keeping the viral load in your body as low as possible over time.

For the best results, you must take Tenfoliv-AF Tablet consistently every single day at the same time. You can take this tablet with or without food, but keeping a strict routine helps you remember your daily dose. Supporting your treatment with liver-friendly lifestyle choices, such as avoiding alcohol and eating a balanced diet, can further support your long-term health.

While taking Tenfoliv-AF Tablet, some people may experience mild side effects like headaches, cough, or joint pain. However, you must contact your healthcare provider immediately if you experience signs of severe liver issues, such as yellowing of your skin or eyes, dark urine, or severe stomach pain.

Before you begin taking this medicine, inform your doctor if you have other health conditions, especially kidney problems or an untreated HIV infection. Do not take this if you are allergic to any of its ingredients, or if you have untreated HIV, as taking this medicine alone can make the HIV virus much harder to treat in the future.

This medicine can interact with certain other treatments, such as tuberculosis drugs or herbal supplements, which can reduce its effectiveness. If you are pregnant, breastfeeding, or an older adult, consult your doctor to discuss whether this medication is safe for your specific situation

Uses of Tenfoliv-AF Tablet

Your doctor may prescribe Tenfoliv-AF Tablet to treat the following conditions:

  • Chronic Hepatitis B Virus (HBV) Infection: Tenfoliv-AF Tablet helps by slowing down the growth of the hepatitis B virus in the body, which reduces the viral load and protects the liver from long-term damage and scarring.

 

Key Benefits

Tenfoliv-AF Tablet provides several clinically proven benefits that help protect your long-term health and well-being:

  • Reduces Viral Activity: By keeping the virus from replicating, it lowers the amount of hepatitis B virus in your blood to highly manageable or undetectable levels.
  • Protects Liver Health: It significantly lowers the risk of developing severe complications like liver scarring (cirrhosis) or liver failure, helping your liver function normally.
  • Kidney and Bone Safety: Compared to older antiviral options, this formulation is highly targeted, meaning it delivers the active treatment directly to liver cells while being gentler on your kidneys and bones.

Directions for Use

  • Tenfoliv-AF Tablet can be taken with meals for better effectiveness.
  • It is usually taken once daily or as advised by your doctor.
  • Swallow Tenfoliv-AF Tablet as a whole with a glass of water.
  • Do not break, chew, or crush it.

How Tenfoliv-AF Tablet Works

Tenfoliv-AF Tablet contains tenofovir alafenamide which belongs to a class of antiviral medicines known as nucleoside reverse transcriptase inhibitors (NRTIs). Once inside your body, the medicine is targeted directly to your liver cells, where the hepatitis B virus attempts to replicate. The medicine works by mimicking the natural building blocks that the virus needs to copy its genetic material. When the virus attempts to use the medicine to replicate itself, the drug blocks the specific enzyme responsible for copying the viral DNA. This halts the replication process, effectively stopping the virus from multiplying and protecting healthy liver cells from infection.
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Alcohol

Unsafe

Avoid drinking alcohol. Consuming alcohol while using Tenfoliv-AF Tablet may worsen the condition.

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Pregnancy

Caution

Tenfoliv-AF Tablet is not recommended during pregnancy. However, your doctor may prescribe it for you during pregnancy if he/she feels that the benefit to you outweighs the risk. You should not take Tenfoliv-AF Tablet without the doctor's advice.

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Breast Feeding

Caution

Consult your doctor, and there is no substantial research yet on the use of Tenfoliv-AF Tablet in breastfeeding/nursing mothers.

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Driving

Caution

Tenfoliv-AF Tablet can cause dizziness. If you feel dizzy when taking Tenfoliv-AF Tablet, do not drive and use any tools or machines.

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Liver

Caution

Consult your doctor before taking Tenfoliv-AF Tablet if you have a liver impairment or any concerns regarding this. Your doctor will weigh the benefits and any potential risks before prescribing them to you.

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Kidney

Caution

Consult your doctor before taking Tenfoliv-AF Tablet if you have kidney impairment or any concerns regarding this. Your doctor will weigh the benefits and any potential risks before prescribing them to you.

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Children

Unsafe

Should not use Tenfoliv-AF Tablet in children below 12 years of age.

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Heart

Consult your doctor

Inform your doctor if you have any existing heart disease. Your doctor will prescribe this medicine only if the potential benefits outweigh the risks.

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Geriatrics

Caution

Limited information is available regarding the usage of Tenfoliv-AF Tablet in elders, so please consult a doctor if you have any concerns.

What if I have taken an overdose of Tenfoliv-AF Tablet

If you accidentally take more than your prescribed dose, seek emergency medical care or call a poison control centre immediately. Keep the medication packaging with you so the healthcare providers know exactly what you took.

Diet & Lifestyle Advise

Supporting your liver health while taking Tenfoliv-AF Tablet can improve your overall treatment outcomes. Consider these evidence-based tips:

  • Avoid alcohol entirely: Alcohol puts extra strain on your liver and can speed up liver damage, countering the benefits of your medication.
  • Eat a liver-friendly diet: Focus on whole foods, including fresh vegetables, fruits, lean proteins, and whole grains. Minimise processed foods, excess sugars, and saturated fats.
  • Stay hydrated: Drink plenty of water throughout the day to help your kidneys filter waste and process your medication efficiently.
  • Maintain a healthy weight: Being overweight can cause fat buildup in the liver, which can worsen hepatitis B complications. Regular, moderate exercise can help manage your weight.
  • Avoid raw or undercooked shellfish: People with chronic liver conditions are highly susceptible to severe infections from bacteria sometimes found in raw seafood.
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How Soon It Starts Working

The time required for Tenfoliv-AF Tablet to start to work: Tenfoliv-AF Tablet ideally shows its action within 1 hour of administration. The time for which the effects of Tenfoliv-AF Tablet last: Tenfoliv-AF Tablet effect lasts for 24 hours.

What if you forget to take Tenfoliv-AF Tablet

If you miss a dose, take it as soon as you remember on that same day. If it is almost time for your next daily dose, skip the missed dose and resume your regular schedule. Do not take two doses at the same time to make up for a missed one.

Storage

• Store the tablets at room temperature, between 20°C and 25°C (68°F to 77°F).• Keep the tablets in their original container with the lid tightly closed to protect them from moisture and light.

Drug Warnings

Do not stop taking this medicine abruptly: Stopping your treatment suddenly can cause a severe, life-threatening flare-up of your hepatitis B infection. Always consult your doctor before making any changes.

  • Check your HIV status: Ensure you are tested for HIV before starting Tenfoliv-AF Tablet. If you have undiagnosed or untreated HIV, taking this medicine alone can cause the HIV virus to become resistant to future treatments.
  • Monitor your lab results: Attend all scheduled appointments for blood work. Your doctor will need to monitor your liver function, viral load, and kidney health regularly.
  • Prevent spreading the virus: Remember that taking Tenfoliv-AF Tablet does not prevent you from passing hepatitis B to others through sexual contact or blood exposure. Use appropriate protection and do not share needles or personal items like razors.
  • Inspect your tablets: Before taking your daily dose, inspect the tablet. Do not take it if it is discoloured, crumbling, or if the packaging has been damaged.

verifiedApollotooltip

Inform your doctor if you are using any of the following medicines, as they may interact with Tenfoliv-AF Tablet.

  • Antiseizure medicines (like carbamazepine, phenytoin, or phenobarbital): These can reduce the levels of Tenfoliv-AF Tablet in your blood, making it less effective at fighting the virus.
  • Tuberculosis medications (like rifampin or rifabutin): These drugs can significantly lower the concentration of Tenfoliv-AF Tablet in your body, reducing its ability to control the infection.
  • Herbal remedies (such as St. John's wort): Taking this supplement can lower the effectiveness of your antiviral treatment.

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verifiedApollotooltip

No clinically significant food interactions are known with Tenfoliv-AF Tablet when used as directed. 

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIVIRALS]

FAQs

Tenfoliv-AF Tablet belongs to the group of medicines known as ‘antiviral medicines used to treat chronic hepatitis B virus (HBV) infection.
Tenfoliv-AF Tablet contains ‘tenofovir alfenamide’. It inhibits HBV replication by merging into viral DNA via HBV reverse transcriptase, resulting in the termination of the DNA chain. This prevents the virus from producing new viruses and cleans up your infection.
No, Tenfoliv-AF Tablet is a prescribed medication given by a physician for treating HBV infection or Chronic hepatitis B. It is recommended not to take it on your own.
Tenfoliv-AF Tablet should be taken in the dose and for the duration prescribed by your doctor based on your medical condition.
The main symptoms include yellowing of eyes and skin, flu-like symptoms, pale stools and dark-coloured urine.
A blood test (HBsAg blood test) can be used to determine if you have hepatitis B or have ever had it.
Practising safe sex and other lifestyle changes along with Tenfoliv-AF Tablet might lower the risk of HIV transmission. However, it may not prevent the spread of hepatitis B virus (HBV) to other people.
Yes, Tenfoliv-AF Tablet is safe if taken in the dose and duration prescribed by the doctor.
Tenfoliv-AF Tablet should be swallowed as a whole with water; do not crush or chew it.
Take another dose of Tenfoliv-AF Tablet if you have vomited within an hour of taking the medicine. However, you may not need to take another dose if it has been more than an hour. Take the next dose at the scheduled time.
If you miss a dose of Tenfoliv-AF Tablet take it as soon as you remember. However, if it is almost time for the scheduled dose, skip the missed dose and take the next dose at the scheduled time.
Tenfoliv-AF Tablet may cause side effects like headaches, diarrhoea, vomiting, feeling sick (nausea), and rash. Most of these side effects may not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
No, Tenfoliv-AF Tablet does not cure chronic hepatitis B, but it helps manage the condition by stopping the virus from multiplying. This lowers the amount of virus in your body and prevents severe liver damage. Talk to your doctor to understand your long-term treatment plan.
If you are pregnant or planning to become pregnant, you should discuss this with your healthcare provider. Your doctor will weigh the benefits of controlling your hepatitis B infection against any potential risks to the baby. Talk to your doctor for personalised guidance.
It is highly recommended that you avoid alcohol completely while taking Tenfoliv-AF Tablet. Alcohol causes additional stress and damage to your liver, which can worsen hepatitis B and make your treatment less effective. Talk to your doctor about safe lifestyle choices.
Chronic hepatitis B is a long-term condition, and most patients need to take Tenfoliv-AF Tablet for several years, or even indefinitely. Stopping the medication early can cause the virus to become active again and lead to severe liver flares. Talk to your doctor before making any changes.
Some medications, including certain antiseizure drugs, antibiotics, and herbal supplements, can interfere with how Tenfoliv-AF Tablet works. Always provide your doctor and pharmacist with a complete list of everything you take, including over-the-counter products. Talk to your doctor or pharmacist before starting any new medicine.
Watch for symptoms like yellowing of your skin or the whites of your eyes, unusually dark urine, severe abdominal pain, persistent nausea, and unusual fatigue. If you notice any of these signs, seek medical attention immediately. Talk to your doctor if you experience any unusual symptoms.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

516, Ring Road Mall, Sector -3, Rohini, New Delhi – 110085
Other Info - TE16290
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