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compositionComposition:TENOFOVIR DISOPROXIL-300MG
prescription
Prescription Medicine
info
Tenohep Tablet 30's
Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Composition :

TENOFOVIR DISOPROXIL-300MG

Manufacturer/Marketer :

Zydus Healthcare Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Tenohep Tablet

Tenohep Tablet is a prescription oral medication used to manage human immunodeficiency virus type 1 (HIV-1) and chronic hepatitis B virus infections. It works by stopping the virus from multiplying in your body, which helps keep your immune system strong and reduces the risk of active liver damage. This medicine does not cure HIV-1 or hepatitis B, but it helps manage these long-term conditions effectively.

To get the best results, you must take Tenohep Tablet consistently every single day at the same time, exactly as your doctor tells you. You can take this tablet with or without food, though taking it with a meal may help if you experience a mild upset stomach. Maintaining a balanced diet and staying well-hydrated are helpful lifestyle habits that support your body while on this treatment.

While taking Tenohep Tablet , you might experience common, mild side effects such as nausea, diarrhea, or feeling unusually tired. However, you must seek medical attention immediately if you notice signs of serious conditions, such as severe stomach pain, unusual muscle pain, or signs of kidney trouble. Your doctor will monitor your health closely to ensure the medication is working safely.

Before starting this treatment, tell your healthcare provider if you have a history of kidney disease, liver problems, or bone thinning. Do not take this medicine if you are already taking other medications that contain the same active ingredients or are known to harm your kidneys. It is also vital to share if you have both HIV-1 and hepatitis B, as stopping this medicine can cause your hepatitis B to worsen suddenly.

Tenohep Tablet can interact with certain pain relievers or other antiviral drugs, which may increase the risk of kidney damage. Avoid drinking alcohol while taking this medicine, as it can place extra stress on your liver. If you are pregnant, planning to become pregnant, breastfeeding, or are an older adult, consult your doctor or pharmacist to discuss the risks and benefits.

Uses of Tenohep Tablet

Tenohep Tablet is used in the treatment of HIV (Human Immunodeficiency Virus) infection and Chronic Hepatitis. The detailed uses of Tenohep Tablet are as follows:

  • HIV-1 Infection: Tenohep Tablet is used in combination with other antiviral medicines to control the virus, protect the immune system, and lower the risk of developing infections.
  • Chronic Hepatitis B: This medicine helps lower the amount of hepatitis B virus in your body, reducing active liver inflammation and preventing long-term liver damage.
  • HIV-1 Pre-Exposure Prophylaxis (PrEP): It is used in combination with other specific antiviral medications to help prevent HIV infection in individuals who are at a higher risk

Key Benefits

  • Immune System Protection (For HIV Management): By keeping the viral load (amount of virus) in your blood extremely low, this medication helps protect your immune cells from being damaged. This keeps your immune system stronger and much better equipped to fight off everyday infections, helping you stay active and healthy.
  • Long-Term Liver Support (For Chronic Hepatitis B): The medication works continuously to slow down and reduce viral activity directly inside the liver. This significantly reduces active inflammation, helps prevent severe liver scarring (cirrhosis), and lowers the risk of long-term liver complications, providing vital support for your ongoing health.
Side effects of Tenohep Tablet
  • Apply a hot/cold pack to the affected area.
  • Doing gentle exercises can help cope with pain by stretching muscles.
  • Get enough sleep. It helps enhance mood and lower pain sensitivity.
  • Avoid alcohol, smoking and tobacco as they can increase pain.
  • Follow a well-balanced meal.
  • Meditation and massages may also help with pain.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.

Directions for Use

  • Swallow the tablet whole with a full glass of water. Do not crush, chew, or split the tablet, as this can affect how the medicine is absorbed into your body.
  • Always follow your doctor's exact instructions regarding how to take this medicine, and never stop taking it without consulting them first.
  • Take your dose at the same time every day to keep a steady level of the medicine in your bloodstream.
  • You can take it with or without food, but keeping a consistent routine is key to managing your condition effectively.
     

How Tenohep Tablet Works

This medicine contains Tenofovir disoproxil. Tenohep Tablet belongs to a class of antiviral medications that act as blockers inside infected cells. When a virus like HIV-1 or hepatitis B attempts to replicate, it relies on specific proteins and enzymes to build new copies of its genetic material. Once you take Tenohep Tablet , the active medicine is absorbed and converted inside your cells. It then mimics the natural building blocks of the virus's DNA. When the virus tries to use this mimic to build its DNA chain, the process is abruptly cut short. This prevents the virus from multiplying, successfully lowering the viral load in your body and allowing your immune system to recover.
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Alcohol

Caution

Consuming alcohol while using Tenohep Tablet may worsen the condition.

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Pregnancy

Caution

Tenohep Tablet is a category B medicine. It should be used with caution in pregnant women.

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Breast Feeding

Caution

In the case of chronic hepatitis B, Tenohep Tablet should be used in breastfeeding mothers only if clinically needed. Avoid breastfeeding if you have HIV.

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Driving

Caution

Tenohep Tablet may cause dizziness. So, avoid driving if you feel dizzy.

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Liver

Caution

Tenohep Tablet should be used with caution if you have liver disease. Dose adjustments may be necessary.

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Kidney

Caution

Tenohep Tablet should not be used in adolescents with kidney failure. In other people with severe kidney diseases, Tenohep Tablet is prescribed only if clinically needed.

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Children

Caution

Tenohep Tablet should be used with caution in children below 12 years of age.

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Heart

Consult your doctor

Inform your doctor if you have any existing heart disease. Your doctor will prescribe this medicine only if the potential benefits outweigh the risks.

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Geriatrics

Caution

Limited information is available regarding the usage of Tenohep Tablet in elders, so please consult a doctor if you have any concerns.

What if I have taken an overdose of Tenohep Tablet

If you take too much of this medicine, seek immediate emergency medical attention or contact a poison control centre right away.

Diet & Lifestyle Advise

  • Drink plenty of water: Because this medication is processed by your kidneys, staying well-hydrated helps your kidneys flush out waste products effectively.
  • Limit alcohol intake: Alcohol can strain your liver and increase the risk of liver damage, especially if you are treating chronic hepatitis B.
  • Eat bone-supporting foods: Since this medication can sometimes cause bone thinning, make sure your diet includes adequate calcium and Vitamin D, or discuss supplements with your doctor.
  • Avoid self-medicating with pain relievers: Common over-the-counter pain medicines like ibuprofen can strain your kidneys. Always ask your pharmacist for kidney-safe alternatives.

Have a query?

How Soon It Starts Working

The time required for Tenohep Tablet to start to work: The time required for Tenohep Tablet to start to work is 1 to 2 hours after administration. The time for which the effects of Tenohep Tablet last: The duration of action for Tenohep Tablet is not clinically established.

What if you forget to take Tenohep Tablet

If you miss a dose, take it as soon as you remember. However, if it is close to the time for your next scheduled dose, skip the missed dose and resume your regular schedule. Do not take two doses at the same time to make up for a missed one.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Do not stop taking Tenohep Tablet suddenly: Stopping this treatment abruptly if you have hepatitis B can cause a severe, life-threatening flare-up of the infection.
  • Check your tablets before taking: Always inspect the tablets before taking your dose; do not use them if they are discolored, cracked, or show signs of moisture damage.
  • Disclose all your medications: Tell every doctor you see that you are taking Tenohep Tablet , especially before starting any new prescription or over-the-counter drugs.
  • Practice safe habits: This medicine reduces the amount of virus in your body but does not prevent the transmission of HIV-1 or hepatitis B to others through sexual contact or blood sharing.

Drug-Drug Interactions

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Drug-Drug Interactions:

  • Kidney-damaging medicines: Taking this medicine with other drugs that can affect kidney function (such as certain antibiotics or high-dose pain relievers like ibuprofen) can increase the risk of serious kidney damage.
  • Other antivirals: Combining Tenohep Tablet with other hepatitis or HIV antivirals may alter medication levels in your body, increasing the risk of side effects.

Drug-Food Interactions:

  • High-fat meals: In some cases, taking certain formulations of this medicine with a very high-fat meal can significantly increase how much drug is absorbed, potentially increasing side effects. Check with your pharmacist regarding your specific brand.

Drug-Disease Interactions:

  • Kidney disease: If you have pre-existing kidney problems, this medicine can accumulate in your body, increasing the risk of side effects. Your doctor may need to adjust your dosing schedule.
  • Hepatitis B and HIV co-infection: If you have both infections, taking this medicine without a complete HIV treatment plan can cause the HIV virus to become resistant to treatment.
Tenofovir disoproxilStreptozocin
Critical
Tenofovir disoproxilDidanosine
Critical

Drug-Drug Interactions

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Tenofovir disoproxilStreptozocin
Critical
How does the drug interact with Tenohep Tablet:
Combining Tenohep Tablet and Streptozocin can increase the risk of kidney problems.

How to manage the interaction:
Taking Tenohep Tablet with Streptozocin is not recommended, as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without talking to your doctor.
Tenofovir disoproxilDidanosine
Critical
How does the drug interact with Tenohep Tablet:
Coadministration of Didanosine with Tenohep Tablet can increase the levels and risk of Didanosine side effects.

How to manage the interaction:
Taking Didanosine with Tenohep Tablet is not recommended, please consult your doctor before taking it. It can be taken if your doctor prescribes it. However, if you experience severe headaches, confusion, weakness, trouble walking, muscle pain, or high fever, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Tenofovir disoproxilIbuprofen
Severe
How does the drug interact with Tenohep Tablet:
Coadministration of Tenohep Tablet and Ibuprofen can increase the risk of developing kidney problems.

How to manage the interaction:
Co-administration of Tenohep Tablet and Ibuprofen can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, vomiting, irregular urination, sudden weight gain or weight loss, shortness of breath, muscle cramps, weakness, and irregular heart rhythm, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
Tenofovir disoproxilVoclosporin
Severe
How does the drug interact with Tenohep Tablet:
Co-administration of Voclosporin and Tenohep Tablet can increase the risk of developing kidney problems.

How to manage the interaction:
Taking Voclosporin and Tenohep Tablet together can lead to an interaction, it can be taken when your doctor advises. However, if you experience any symptoms like vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, shortness of breath, muscle cramps, dizziness, and irregular heart rhythm, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
Tenofovir disoproxilRifapentine
Severe
How does the drug interact with Tenohep Tablet:
Combining Rifapentine and Tenohep Tablet can reduce the blood levels of Tenohep Tablet.

How to manage the interaction:
Taking Tenohep Tablet and Rifapentine together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you experience any symptoms, contact the doctor immediately. Do not discontinue any medications without consulting your doctor.
Tenofovir disoproxilOlsalazine
Severe
How does the drug interact with Tenohep Tablet:
Coadministration of Olsalazine and Tenohep Tablet can increase the risk of developing kidney problems.

How to manage the interaction:
Taking Olsalazine and Tenohep Tablet together can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like vomiting, increased or decreased urination, sudden weight gain or weight loss, shortness of breath, muscle cramps, dizziness, and irregular heart rhythm, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
Tenofovir disoproxilPiroxicam
Severe
How does the drug interact with Tenohep Tablet:
Coadministration of Piroxicam and Tenohep Tablet can increase the risk of kidney damage.

How to manage the interaction:
Co-administration of Tenohep Tablet with Piroxicam can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, decreased appetite, increased or decreased urine, weight gain or loss that occurs suddenly, swelling, difficulty breathing, muscle pain, dizziness, and irregular heartbeat, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
Tenofovir disoproxilPhenobarbital
Severe
How does the drug interact with Tenohep Tablet:
Coadministration of Phenobarbital and Tenohep Tablet can reduce the levels of Tenohep Tablet, which can lead to low treatment outcomes.

How to manage the interaction:
Taking Tenohep Tablet with Phenobarbital can result in an interaction, it can be taken when a doctor has advised it. Do not discontinue any medications without consulting a doctor.
Tenofovir disoproxilCelecoxib
Severe
How does the drug interact with Tenohep Tablet:
Coadministration of Celecoxib with Tenohep Tablet may increase the risk of kidney problems.

How to manage the interaction:
Taking Celecoxib with Tenohep Tablet together can possibly result in an interaction, but it can be taken if your doctor has advised it. Consult the doctor immediately if you experience symptoms such as nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, shortness of breath, muscle cramps, or dizziness. Do not discontinue any medications without consulting a doctor.
Tenofovir disoproxilValdecoxib
Severe
How does the drug interact with Tenohep Tablet:
Combining Valdecoxib and Tenohep Tablet can increase the risk of kidney problems.

How to manage the interaction:
Taking Valdecoxib and Tenohep Tablet together can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTIRETROVIRAL AGENTS]

FAQs

Tenohep Tablet is used to treat HIV infection and chronic hepatitis B.

Tenohep Tablet does not affect fertility. However, consult your doctor immediately if you develop any side effects while using Tenohep Tablet .

Tenohep Tablet should be taken as prescribed by your doctor. Abrupt stopping of this medicine may lead to resistance to other medications making the infection difficult to treat.

Tenohep Tablet is used to treat HIV-1 virus so you can take the Tenohep Tablet but if you are suffering with tuberculosis then you should consult the doctor. Inform about your medical conditions and take Tenohep Tablet only if it is advised by your physician. Do not self-medicate.

In case of HIV-1 infection, Tenohep Tablet may reduce the risk of passing the virus to others, but the chances of infecting others can still be there. In case of HBV infection, Tenohep Tablet has not proven to reduce the risk of passing the virus to others.

You should take the Tenohep Tablet for as long as it is prescribed by the doctor. Do not stop using it without the notice of the doctor until the course is completed as it may worsen your condition.

If you vomit within 1 hour of taking Tenohep Tablet , then take the other tablet. If you vomit more than 1 hour after taking Tenohep Tablet , then do not take another dose.

No, Tenohep Tablet does not cure HIV-1 or hepatitis B. Instead, it helps control the virus, lowers the viral load in your body, and protects your immune system and liver from further damage. Talk to your doctor about long-term management goals.

Some pregnant individuals may need to continue this medication to protect their health and prevent passing the virus to the baby. However, you must discuss the risks and benefits with your doctor to make a safe, individualized plan.

Tenohep Tablet is processed by the kidneys and can sometimes cause kidney damage or decreased kidney function over time. Your doctor will order regular blood and urine tests to monitor your kidney health while you are on this medicine. Talk to your doctor if you experience changes in urination.

It is highly recommended to avoid or strictly limit alcohol while taking Tenohep Tablet . Alcohol can place extra strain on your liver and increase the risk of liver damage, particularly if you are treating chronic hepatitis B. Talk to your doctor for personalized advice.

You should avoid taking frequent or high doses of pain relievers like ibuprofen while taking Tenohep Tablet , as both can strain your kidneys and increase the risk of kidney problems. Speak to your pharmacist or doctor about safer alternatives for pain relief.

Yes, Tenohep Tablet can sometimes cause a reduction in bone mineral density, which may increase the risk of bone thinning or fractures. Your doctor may monitor your bone health and recommend calcium or Vitamin D supplements. Talk to your doctor if you have a history of bone issues.

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While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

D' Block, 3Rd Floor, Gillander House, Netaji Subhas Road, Kolkata - 700001 (Wb)
Other Info - TEN0920

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