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compositionComposition:TERBINAFINE-500MG
prescription
Prescription Medicine
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Terfine-500 Tablet is an antifungal medicine that is used to treat fungal infections of toenails, fingernails, and tinea capitis (scalp ringworm). This medicine contains terbinafine, which works by inhibiting the fungal cell membrane and thereby kills the infection-causing fungus. Common side effects include diarrhoea, stomach pain, headache, and a change in taste or loss of taste.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

TERBINAFINE-500MG

Manufacturer/Marketer :

Bioswizz Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Terfine-500 Tablet

Terfine-500 Tablet is used to treat fungal infections of toenails and fingernails. It is also used to treat tinea capitis (scalp ringworm). Fungal nail infections (onychomycosis) are common infections of toenails or fingernails that cause the nail to become thick, discoloured, or more likely to break.

Terfine-500 Tablet contains Terbinafine, which works by damaging the fungal cell membranes, which are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents.

Some people may experience diarrhoea, stomach pain, headache, and a change in taste or loss of taste. Most of these side effects of Terfine-500 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Terbinafine, avoid taking Terfine-500 Tablet . If you are pregnant or breastfeeding, it is recommended to consult a doctor before using Terfine-500 Tablet . If you have depressive symptoms such as feeling worthless or sad, loss of interest or energy in daily activities, mood changes, restlessness, or a change in sleep pattern, inform your doctor immediately.

Uses of Terfine-500 Tablet

Terfine-500 Tablet is used in the treatment of fungal infections. The detailed uses of Terfine-500 Tablet are as follows:

  • Treatment of onychomycosis: Terfine-500 Tablet is usually prescribed for fungal infections of the fingernails and toenails.
  • Management of tinea corporis: Terfine-500 Tablet is used to treat ringworm infections throughout the body.
  • Relief of tinea cruris: Terfine-500 Tablet is used to manage fungal infections in the groin area, also known as jock itch.
  • Control of tinea pedis: Terfine-500 Tablet effectively treats athlete’s foot, a fungal infection of the feet.
  • Treatment of tinea capitis: Terfine-500 Tablet is used to treat scalp ringworm, especially in children.
  • in resistant fungal infections: Terfine-500 Tablet is used to treat fungal infections that do not respond well to topical treatments.

Key Benefits

  • Terfine-500 Tablet is an antifungal medicine used to treat fungal infections of toenails and fingernails.
  • It is also used to treat tinea capitis (scalp ringworm).
  • Terfine-500 Tablet destroys fungal cell membranes that are essential for their survival and stop the leakage of cell contents.

Directions for Use

  • Terfine-500 Tablet can be taken with or without food as advised by your doctor.
  • It is usually taken once daily; however, follow your doctor's advice regarding the dosage and duration.
  • Swallow the medicine as a whole with a glass of water.
  • Do not crush, chew or break it.

How Terfine-500 Tablet Works

Terfine-500 Tablet contains Terbinafine, an antifungal that works by damaging the fungal cell membranes, which are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thereby, kills fungi and clears the fungal infection.
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Alcohol

Consult your doctor

Interaction of alcohol with Terfine-500 Tablet is unknown. Please consult a doctor before consuming alcohol with Terfine-500 Tablet .

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Pregnancy

Consult your doctor

Terfine-500 Tablet is a Category B pregnancy drug and is given to a pregnant woman only if the doctor thinks the benefits outweigh the risks.

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Breast Feeding

Unsafe

Terfine-500 Tablet may be excreted in human milk and harm the baby. Therefore, it is not advised for breastfeeding mothers.

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Driving

Caution

Terfine-500 Tablet may cause dizziness. Therefore, drive only if you alert after taking Terfine-500 Tablet .

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Liver

Consult your doctor

If you have liver disease, inform your doctor before taking Terfine-500 Tablet . Your doctor may adjust the dose or prescribe a suitable alternative based on your condition.

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Kidney

Consult your doctor

If you have kidney problems, inform your doctor before taking Terfine-500 Tablet . Your doctor may adjust the dose or prescribe a suitable alternative based on your condition.

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Children

Unsafe

Terfine-500 Tablet is not recommended for children below 12 years as the safety and effectiveness were not established.

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Heart

Caution

Terfine-500 Tablet should be used with caution in patients with heart problems. Therefore, please consult your doctor before using Terfine-500 Tablet .

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Geriatrics

Consult your doctor

Please consult a doctor before administering Terfine-500 Tablet to geriatric patients. Your doctor will prescribe Terfine-500 Tablet if the benefits outweigh the risks.

What if I have taken an overdose of Terfine-500 Tablet

Avoid taking more than the prescribed dose of Terfine-500 Tablet . Overdose symptoms may include headache, dizziness, vomiting, stomach pain, rash, and increased urination. Seek immediate medical help if an overdose is suspected.

Diet & Lifestyle Advise

Fungal nail infections (onychomycosis):

  • Keep your feet and hands clean and dry.
  • Cut your toenails and fingernails short and keep them clean.
  • Avoid sharing nail clippers with others.
  • In wet places such as changing rooms and gym showers, wear footwear to prevent fungal infections.
  • Choose a clean and licensed salon and make sure that all the instruments in the salon are sterilised after each use.
  • Avoid sun exposure while taking Terfine-500 Tablet as it may make skin more sensitive to sunlight. Wear protective clothing and use sunscreen while going out to protect your skin from sunburn.

Tinea capitis (scalp ringworm):

  • Shampoo your child's scalp regularly, especially after a haircut.
  • Use scalp conditioning products such as pomades with selenium and coconut oil, as they might help to prevent scalp ringworm.
  • Make sure your children wash their hands regularly, even after playing with pets, and keep their skin clean and dry.
  • Avoid infected animals.
  • Keep shared areas clean, especially childcare centres and schools.
  • Teach children to avoid sharing personal items such as towels, clothing, hairbrushes, etc.
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How Soon It Starts Working

The time required for Terfine-500 Tablet to start to work: The onset time of Terfine-500 Tablet has not been clinically established. 

The time for which the effects of Terfine-500 Tablet last: The duration of Terfine-500 Tablet ’s effect is clinically not established.

What if you forget to take Terfine-500 Tablet

If you miss a dose of Terfine-500 Tablet , take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed dose.

Storage

• Store in a cool and dry place away from sunlight.• Keep Terfine-500 Tablet out of the sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • If you are allergic to terbinafine, avoid taking Terfine-500 Tablet .
  • If you are pregnant or a nursing mother, it is advised to consult a doctor before using Terfine-500 Tablet .
  • Avoid or limit sun exposure while using Terfine-500 Tablet as it may make skin more sensitive to sunlight. 
  • Wear protective clothing and use sunscreen while going out to protect your skin from sunburn.
  • If you have lupus (an autoimmune disease), a weakened immune system, kidney or liver problems, inform your doctor before taking Terfine-500 Tablet .
  • If you have depressive symptoms such as feeling worthless or sad, loss of interest or energy in daily activities, mood changes, restlessness, or a change in sleep pattern, inform your doctor immediately.

Drug-Drug Interactions

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Drug-Drug Interaction: Terfine-500 Tablet may interact with drugs used to treat stomach ulcers (cimetidine), antibiotics (rifampicin), antifungal (fluconazole), medicine used to treat high blood pressure (metoprolol), antidepressants (duloxetine, desipramine), opioid pain killers (codeine, tramadol), blood thinners (warfarin), heart-related medicines (amiodarone) and immunosuppressant (ciclosporin).

Drug-Food Interaction: Terfine-500 Tablet may interact with caffeine. Therefore, avoid foods containing chocolate and caffeine, such as cocoa beans, tea, coffee, cola, and energy drinks, as they may increase the adverse effects of caffeine.

Drug-Disease Interaction: If you have lupus (an autoimmune disease), a weakened immune system, kidney or liver problems, inform your doctor before taking Terfine-500 Tablet .

TerbinafineThioridazine
Critical
TerbinafinePimozide
Critical

Drug-Drug Interactions

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TerbinafineThioridazine
Critical
How does the drug interact with Terfine-500 Tablet:
Co-administration of Thioridazine together with Terfine-500 Tablet can increase the blood levels of Thioridazine and increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Thioridazine and Terfine-500 Tablet is not recommended as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
TerbinafinePimozide
Critical
How does the drug interact with Terfine-500 Tablet:
Co-administration of Pimozide and Terfine-500 Tablet can increase the blood levels of pimozide and the risk of side effects.

How to manage the interaction:
Co-administration of pimozide and Terfine-500 Tablet is not recommended as it can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like muscle spasms or movements that you can't stop or control, such as lip smacking, chewing, puckering, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye-rolling, shaking or jerking of arms and legs, tremor, jitteriness, restlessness, pacing, and foot tapping, dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
TerbinafineEliglustat
Severe
How does the drug interact with Terfine-500 Tablet:
Coadministration of Terfine-500 Tablet with Eliglustat can increase the levels and side effects of Eliglustat.

How to manage the interaction:
Although there is a possible interaction between Terfine-500 Tablet and Eliglustat, you can take these medicines together if prescribed by your doctor. However, if you experience nausea, upset stomach, abdominal pain, gas/bloating, diarrhea, headache, back pain, arm/leg pain, dizziness, or weakness, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
TerbinafineTeriflunomide
Severe
How does the drug interact with Terfine-500 Tablet:
Co-administration of Teriflunomide and Terfine-500 Tablet can increase the risk or severity of liver problems.

How to manage the interaction:
Co-administration of Teriflunomide and Terfine-500 Tablet can lead to an interaction, but it can be taken if your doctor advises. However, if you experience symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
TerbinafineTamoxifen
Severe
How does the drug interact with Terfine-500 Tablet:
Co-administration of Tamoxifen with Terfine-500 Tablet may reduce the effectiveness of Tamoxifen.

How to manage the interaction:
Although taking Tamoxifen and Terfine-500 Tablet together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience any symptoms, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
TerbinafinePitolisant
Severe
How does the drug interact with Terfine-500 Tablet:
Co-administration of Pitolisant and Terfine-500 Tablet can increase the risk of an irregular heart rhythm and increase the blood levels of Pitolisant.

How to manage the interaction:
Co-administration of Pitolisant and Terfine-500 Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like headache, insomnia, nausea, anxiety, increased heart rate, hallucinations, abdominal pain, and muscle pain, diarrhea or vomiting, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
TerbinafineDextromethorphan
Severe
How does the drug interact with Terfine-500 Tablet:
Co-administration of Dextromethorphan and Terfine-500 Tablet may increase the side effects of Dextromethorphan.

How to manage the interaction:
Taking Dextromethorphan and Terfine-500 Tablet together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any symptoms like difficulty breathing, dizziness, drowsiness, anxiety, restless feeling, nervousness, confusion, or diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
TerbinafineLeflunomide
Severe
How does the drug interact with Terfine-500 Tablet:
Co-administration of Leflunomide and Terfine-500 Tablet can increase the risk or severity of liver problems.

How to manage the interaction:
Although there is an interaction between leflunomide and Terfine-500 Tablet, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
TerbinafineLomitapide
Severe
How does the drug interact with Terfine-500 Tablet:
Co-administration of Lomitapide and Terfine-500 Tablet can increase the risk or severity of liver problems.

How to manage the interaction:
Co-administration of Lomitapide and Terfine-500 Tablet can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
TerbinafineVortioxetine
Severe
How does the drug interact with Terfine-500 Tablet:
Co-administration of Vortioxetine and Terfine-500 Tablet can increase the blood levels and side effects of vortioxetine like serotonin syndrome (A condition in which a chemical called serotonin builds up in your body)

How to manage the interaction:
Co-administration of Vortioxetine and Terfine-500 Tablet can lead to an interaction, but it can be taken if a doctor advises. However, if you experience any symptoms like confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramps, nausea, vomiting, diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIFUNGALS - ORAL]

FAQs

Terfine-500 Tablet is used to treat fungal infections of toenails and fingernails.
Terfine-500 Tablet works by damaging the fungal cell membranes that are essential for their survival, as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thereby, kills fungi and clears the fungal infection.
You are recommended to avoid foods containing chocolate and caffeine, such as cocoa beans, tea, coffee, cola and energy drinks, while taking Terfine-500 Tablet as it may increase the adverse effects of caffeine.
Terfine-500 Tablet may increase the skin sensitivity to sunlight. Therefore, avoid or limit exposure to sunlight and sunlamps. You are advised to use sunscreen and wear protective clothing while going out to prevent sunburn. However, if you notice any unusual skin sensitivity while using Terfine-500 Tablet , such as a rash, please consult a doctor.
Terfine-500 Tablet may cause changes in taste or loss of taste as a side effect. It may usually improve within several weeks after stopping Terfine-500 Tablet , but may become permanent or last for a long time. However, if you have a poor appetite, unintended weight loss, loss of taste or changes in taste or a change in mood or depressive symptoms, inform your doctor.
You are not recommended to stop using Terfine-500 Tablet without consulting your doctor, as it may cause recurring infections. Therefore, take Terfine-500 Tablet for as long as your doctor has prescribed it, and if you experience any difficulty while taking Terfine-500 Tablet , please consult your doctor.
Terfine-500 Tablet is not recommended for patients with chronic or active liver disease. Your doctor may recommend a liver function test to monitor whether your liver is functioning effectively. This is done since the medicine gets metabolised by liver enzymes, and any inefficiency in liver function can lead to increased levels of Terfine-500 Tablet in the blood, resulting in increased side effects and toxicity. Therefore, inform your doctor if you have any liver disease or cirrhosis and about the medicines you may be taking, as taking Terfine-500 Tablet with another medicine can lead to liver toxicity.
Yes, Terfine-500 Tablet may cause skin reactions in sensitive people. There are rare reports of people developing serious skin/hypersensitivity reactions like toxic epidermal necrolysis, Stevens-Johnson syndrome, and other severe skin reactions with Terfine-500 Tablet . Therefore, do not take Terfine-500 Tablet without consulting your doctor. If you experience any type of skin reaction or rashes, stop taking it immediately and inform your doctor.
Terfine-500 Tablet is effective as an antifungal medicine if taken in the dose and duration advised by your doctor. Do not discontinue taking it even if you see improvement in your condition. If you stop taking Terfine-500 Tablet too early, the fungus may continue to grow and the infection may recur or worsen.
You are recommended to take Terfine-500 Tablet for as long as your doctor advises. The usual duration of treatment for Tinea corporis (ringworms), Tinea pedis (fungal infection in the foot), and Tinea cruris (fungal infection in the groin) is about 2 to 4 weeks, though it can occasionally be extended to 6 weeks. Treatment for fungal infections of nails typically varies from 6 to 12 weeks, with fingernail fungal infections taking up to 6 weeks and toenail fungal infections taking up to 12 weeks. However, the exact duration is determined by the doctor, depending on the site of infection, the type of infection, and the patient’s response to the therapy.
Caffeinated drinks such as tea and coffee should be taken with caution while on treatment with Terfine-500 Tablet . Terfine-500 Tablet decreases the metabolism rate of caffeine by 19% which is a key constituent of coffee, thereby increasing the caffeine levels in the blood and may lead to side effects such as headache, jitteriness, increased heartbeat, and restlessness.
Yes, Terfine-500 Tablet can be taken with or without food.
Terfine-500 Tablet may cause side effects such as nausea, indigestion, diarrhea, stomach pain, taste disturbance and headache. If these side effects persist or worsen, please consult your doctor.
Avoid alcohol consumption while taking Terfine-500 Tablet and use sunscreen while going out in the sun, as Terfine-500 Tablet may increase skin sensitivity. Regular monitoring of liver function is recommended while taking Terfine-500 Tablet .
Pregnant and breastfeeding women are advised to consult their doctor before taking Terfine-500 Tablet to discuss the possible risks and benefits.
If you suspect an overdose of Terfine-500 Tablet , seek medical help immediately. Symptoms may include dizziness, nausea, and vomiting.

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While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. U.S. Food and Drug Administration (FDA). 020539S021Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026]Check here
  2. U.S. Food and Drug Administration (FDA). 022071S009Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026]Check here
  3. National Health Service (NHS). Terbinafine - NHS Medicines Reference Guide. London, UK: NHS; 2025. [Accessed on 02 Jun. 2026]Check here
  4. Ema.Terbinafine. [Accessed on 27 Oct 2025]Check here
  5. Webmd. Terbinafine. [Accessed on 27 Oct 2025]Check here
  6. Lactmed.Terbinafine. [Accessed on 27 Oct 2025]Check here
  7. Luke Maxfield; Charles V. Preuss; Rene Bermudez. Terbinafine. StatPearls. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. October 2022. [Accessed on 10th January 2023]Check here

Country of origin

India

Manufacturer/Marketer address

new no 241 old no 92/15, sathangadu colony street, tiruvottiyur, chennai - 600019
Other Info - TER0479
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