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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Thiokem-D Injection is used to treat acute musculoskeletal pain and muscle spasms. It contains Diclofenac and Thiocolchicoside. Diclofenac is a non-steroidal anti-inflammatory drug (pain killer/NSAID) with analgesic properties. It inhibits cyclo-oxygenase (COX) enzymes and further prevents the formation of chemical messengers, 'prostaglandins' (PGs), that cause pain and swelling at the injured or damaged site. Thiocolchicoside is a muscle relaxant that works on the spinal cord and brain centres. This process helps reduce muscle stiffness and improves muscle movements, thus relieving pain due to muscle spasms.
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Consume Type :

PARENTERAL

Return Policy :

Not Returnable

About Thiokem-D Injection

Thiokem-D Injection is a combination medication primarily used to treat acute musculoskeletal pain and muscle spasms. Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body.

Thiokem-D Injection is a combination of Diclofenac and Thiocolchicoside. Diclofenac is a non-steroidal anti-inflammatory drug (pain killer/NSAID) with analgesic properties. It inhibits cyclo-oxygenase (COX) enzymes and further prevents the formation of chemical messengers, 'prostaglandins' (PGs), that cause pain and swelling at the injured or damaged site. Thiocolchicoside is a muscle relaxant that works on the centres of the spinal cord and brain. This process helps reduce muscle stiffness and improves muscle movements, thus relieving pain due to muscle spasms.

A healthcare professional will administer this medicine. Common side effects of Thiokem-D Injection include headache, stomach upset, constipation, dizziness, drowsiness, diarrhoea, pain, swelling, and redness at the injection site. These side effects are not familiar to everyone and vary individually. However, if the side effects are persistent, please consult your doctor.

Before starting Thiokem-D Injection, inform your doctor if you have any liver, heart or kidney diseases, high blood pressure, diabetes, stomach ulcers, asthma, and auto-immune conditions like systemic lupus erythematosus. Pregnant and breastfeeding women should consult their doctor before using Thiokem-D Injection. Avoid consuming alcohol while undergoing treatment with Thiokem-D Injection. This medicine is not recommended for children and adolescents below 18 years of age as safety has not been established. However, please seek medical advice.

Uses of Thiokem-D Injection

Treatment of Acute musculoskeletal pain and muscle spasms

Directions for Use

It will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Thiokem-D Injection treats acute musculoskeletal pain and muscle spasms. It contains Diclofenac and Thiocolchicoside. Diclofenac is a non-steroidal anti-inflammatory drug (NSAID) and relieves pain. It inhibits cyclo-oxygenase (COX) enzymes that further prevent the formation of chemical messengers called 'prostaglandins' (PGs). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking the COX enzymes' effect, lesser PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site. Thiocolchicoside is a muscle relaxant that works on the centres of the spinal cord and brain. This process helps reduce muscle stiffness and improves muscle movements, thus relieving pain due to muscle spasms.

How Thiokem-D Injection Works

Thiokem-D Injection is a combination of Diclofenac and Thiocolchicoside. Diclofenac is a non-steroidal anti-inflammatory drug (pain killer/NSAID) with analgesic properties. It inhibits cyclo-oxygenase (COX) enzymes and further prevents the formation of chemical messengers, 'prostaglandins' (PGs), that cause pain and swelling at the injured or damaged site. Thiocolchicoside is a muscle relaxant that works on the centres of the spinal cord and brain. This process helps reduce muscle stiffness and improves muscle movements, thus relieving pain due to muscle spasms.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Thiokem-D Injection

As Thiokem-D Injection is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. However, if you think there has been an overdose or experiencing any adverse events, get medical care right away.

Drug Warnings

Inform your doctor if you have any liver, heart or kidney diseases, high blood pressure, diabetes, stomach ulcers, gastrointestinal diseases, asthma, and autoimmune diseases (systemic lupus erythematosus) before being treated with Thiokem-D Injection. Please consult your doctor before starting Thiokem-D Injection if you have high cholesterol, chickenpox, porphyria (rare inherited disorder), hereditary disorders like Lapp lactase deficiency (lactose intolerance), galactose intolerance, glucose-galactose malabsorption (small intestines not being able to absorb and use glucose and galactose), fits, and blood clotting disorders. Do not take any other NSAIDs for pain relief along with Thiokem-D Injection unless prescribed. Stop using Thiokem-D Injection and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach, such as blood in stools. Thiokem-D Injection is not recommended for pregnant and breastfeeding women; hence, please seek medical advice. This medicine may cause dizziness and drowsiness, so drive only if you are alert and focused. Thiokem-D Injection is not recommended in children and adolescents below 18 years as safety and efficacy are not established.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Thiokem-D Injection:
Co-administration of Thiokem-D Injection with Meloxicam can increase the risk or severity of gastrointestinal side effects.

How to manage the interaction:
Taking Meloxicam with Thiokem-D Injection is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop any medication without doctor's advise.
How does the drug interact with Thiokem-D Injection:
Taking prasugrel together with Thiokem-D Injection may increase the risk of bleeding.

How to manage the interaction:
Co-administration of Thiokem-D Injection and Prasugrel can lead to an interaction; it can be taken if advised by a doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Thiokem-D Injection:
Co-administration of methotrexate with Thiokem-D Injection can increase the levels and effects of methotrexate. This can lead to increased risk of side effects.

How to manage the interaction:
Although there is a possible interaction between methotrexate and Thiokem-D Injection, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as mouth sores or ulcers, nausea, vomiting, diarrhea, rash, loss of hunger, joint pain or swelling, yellowing of the skin or eyes, dark urine, shortness of breath, a dry cough, paleness, dizziness or fainting, unusual bruising or bleeding, fits, infection, fever, chills, body aches, sore throat or muscle weakness, consult a doctor immediately. Do not stop using medications without a doctor's advice.
How does the drug interact with Thiokem-D Injection:
Taking Thiokem-D Injection with bromfenac will have an additive effect and may increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding, ulceration, and rarely, perforation.

How to manage the interaction:
There may be possible interaction between Thiokem-D Injection and bromfenac but you can take it if prescribed by a doctor. Consult your doctor if you experience any unusual bleeding or bruising or have other signs and symptoms of bleeding such as dizziness; lightheadedness; red or black, tarry stools; coughing up or vomiting fresh or dried blood that looks like coffee grounds; severe headache; and weakness. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Thiokem-D Injection:
Taking Thiokem-D Injection with Enoxaparin can increase the risk of bleeding complications.

How to manage the interaction:
There may be a possible interaction between Thiokem-D Injection and Enoxaparin, but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience any unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Do not discontinue any medications without consulting a doctor.
DiclofenacLomitapide
Severe
How does the drug interact with Thiokem-D Injection:
Taking Thiokem-D Injection with Lomitapide will have an additive effect and may cause liver problems.

How to manage the interaction:
There may be a possible interaction between Thiokem-D Injection and Lomitapide, but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you have fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark colored urine, light colored stools, and/or yellowing of the skin or eyes. Do not stop using any medications without a doctor's advice.
DiclofenacMipomersen
Severe
How does the drug interact with Thiokem-D Injection:
Co-administration of Thiokem-D Injection with Mipomersen may cause liver problems.

How to manage the interaction:
Co-administration of Thiokem-D Injection and Mipomersen can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, fatigue, nausea, vomiting, abdominal pain, dark urine, pale stools, and/or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Thiokem-D Injection:
Coadministration of Thiokem-D Injection with fondaparinux may increase the risk of bleeding.

How to manage the interaction:
There may be a possible interaction between Thiokem-D Injection and Fondaparinux when taken together, but they can be taken together if your doctor has prescribed them. However, if you experience bleeding, severe back pain, dizziness, black or red stools, severe headache, weakness, and vomiting contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Thiokem-D Injection:
Taking Thiokem-D Injection and ibuprofen can increase the risk of stomach bleeding and ulcers.

How to manage the interaction:
Co-administration of Thiokem-D Injection and Ibuprofen can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Thiokem-D Injection:
Taking Thiokem-D Injection with warfarin may, increase the risk of bleeding.

How to manage the interaction:
There may be a possible interaction between Thiokem-D Injection and Warfarin, but they can be taken together if a doctor has prescribed them. However, consult your doctor immediately if you experience unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, contact a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Exercising regularly helps in muscle stretching, reducing spasm, tear and sprain incidence. Mild exercises, such as jogging and walking, are helpful for muscle stretching.
  • Massages can also be helpful to ease the pain.
  • Avoid wearing tight-fitting clothes; wear loose garments for proper blood circulation.
  • Rest well and get plenty of sleep.
  • Hot or cold therapy can help treat muscle spasms. Apply an ice or hot pack on the muscle for 15-20 minutes.
  • Stay hydrated; drink plenty of water.

Habit Forming

No

Therapeutic Class

MUSCLE RELAXANTS
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Alcohol

Caution

Please seek medical advice if you have a regular alcohol intake habit before taking Thiokem-D Injection

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Pregnancy

Unsafe

Thiokem-D Injection is not recommended during pregnancy as it may harm your developing baby. Please consult your doctor for more information.

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Breast Feeding

Unsafe

Thiokem-D Injection is not recommended during breastfeeding as it may be excreted in breast milk. Please consult your doctor for more information.

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Driving

Caution

Thiokem-D Injection may make you feel dizzy and sleepy. Do not drive or operate machinery if you experience dizziness or drowsiness after taking Thiokem-D Injection.

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Liver

Caution

Thiokem-D Injection should be used cautiously in patients with liver impairment/liver disease. If you have liver disease, please inform your doctor before receiving this medicine.

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Kidney

Caution

Thiokem-D Injection should be used cautiously in patients with kidney impairment/liver disease. If you have kidney disease, please inform your doctor before receiving this medicine.

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Children

Unsafe

Thiokem-D Injection is not recommended for use in children as the safety and efficacy data are not established. Please seek medical advice for more information.

Have a query?

FAQs

Thiokem-D Injection is used to treat Acute musculoskeletal pain and muscle spasms.

Thiokem-D Injection contains Diclofenac and Thiocolchicoside. Diclofenac works by blocking the action of certain chemical messengers that cause pain and inflammation at the injured or damaged site. Thiocolchicoside is a muscle relaxant which relieves muscle stiffness due to muscle spasms and improves muscle movements.

Diarrhoea can be a side-effect of Thiokem-D Injection. Drink enough fluids and eat fibre-rich food if you experience diarrhoea. If you find blood in the stools (tarry stools) or experience excess diarrhoea, consult your doctor. Do not take anti-diarrhoeal medicine on your own.

Using other NSAIDs or painkillers is not advised while using Thiokem-D Injection. Please seek medical advice for further information.

You are not recommended to take Thiokem-D Injection with warfarin as simultaneous use of these two medicines may increase the effect of anti-coagulants/blood thinners and cause bleeding risk. Please seek medical advice for more information.

Country of origin

India
Other Info - TH97722

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