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compositionComposition:ELTROMBOPAG-25MG
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Prescription Medicine
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Thromplat 25 mg Tablet is used to treat low platelet count. It contains Eltrombopag which works by causing the cells in the bone marrow to produce more platelets. In some cases, this medicine may cause side effects such as nausea, diarrhea, headache, muscle pain, tiredness, loss of appetite, fever, and cough. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

ELTROMBOPAG-25MG

Manufacturer/Marketer :

Aureate Healthcare

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Thromplat 25 mg Tablet

Thromplat 25 mg Tablet is a prescription oral medicine used to treat low blood platelet counts (thrombocytopenia) in patients with chronic immune thrombocytopenia (ITP) when other treatments have not worked well. It is also prescribed to treat severe aplastic anemia and low platelets caused by chronic hepatitis C infection.

To get the best results, you must take Thromplat 25 mg Tablet consistently every day exactly as directed by your doctor. You should take Thromplat 25 mg Tablet on an empty stomach, either at least 1 hour before or 2 hours after eating. Avoid consuming dairy products, calcium-fortified juices, or mineral supplements close to your dose, as they can stop your body from absorbing the medicine.

While taking Thromplat 25 mg Tablet , you may experience mild side effects like nausea, diarrhea, or muscle aches. However, you must contact your doctor immediately if you notice signs of liver damage, such as yellowing of your eyes or skin, dark urine, or unusual tiredness.

Before starting Thromplat 25 mg Tablet , tell your doctor if you have a history of liver disease, blood clots, or cataracts. Do not take this if you are allergic to any of its ingredients. A long-term blood condition can feel stressful, especially when frequent blood tests and bleeding risks affect daily life. Thromplat 25 mg Tablet is prescribed to help improve platelet counts and support your ongoing treatment plan.

Thromplat 25 mg Tablet can interact with certain medications, including antacids, cholesterol-lowering drugs, and mineral supplements, which can make it less effective. If you are pregnant, planning to become pregnant, breastfeeding, or are an older adult, consult your doctor or pharmacist to discuss whether Thromplat 25 mg Tablet is safe for you. Thromplat 25 mg Tablet may also be prescribed for children aged 1 year and older with chronic immune thrombocytopenia (ITP) when other treatments have not worked well. The dose for children is carefully determined by a specialist.

Uses of Thromplat 25 mg Tablet

Thromplat 25 mg Tablet is used in the treatment of low platelet count (thrombocytopenia) in various blood-related disorders. The detailed uses of Thromplat 25 mg Tablet are as follows:

  • Chronic immune thrombocytopenia (ITP): Thromplat 25 mg Tablet helps raise platelet counts in patients with chronic ITP to reduce the risk of bleeding when other treatments have failed.
  • Severe aplastic anemia: Thromplat 25 mg Tablet helps the bone marrow produce more blood cells, including platelets, in patients whose condition has not responded to other therapies.
  • Hepatitis C-associated low platelets: Historically, Thromplat 25 mg Tablet was used to increase platelet counts so some patients with chronic hepatitis C could receive interferon-based treatment. Today, newer antiviral medicines are more commonly used, and your doctor will decide whether Thromplat 25 mg Tablet is appropriate for your treatment plan. 

Key Benefits

  • Helps reduce bleeding: Raises platelet counts to lower the risk of bruising and bleeding.
  • Supports important treatments: Helps patients receive necessary medical procedures or other treatments safely.
  • May reduce transfusions: Helps decrease the need for frequent platelet transfusions in some patients
Side effects of Thromplat 25 mg Tablet
  • Get plenty of rest and sleep.
  • Keep your body warm.
  • Drink plenty of fluids to stay hydrated.
  • Avoid strenuous activities.
  • Maintain good hygiene to prevent flu from spreading.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the steps to manage Joint Pain caused by medication usage:
  • Please inform your doctor about joint pain symptoms, as they may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Your doctor may prescribe common pain relievers if necessary to treat joint discomfort.
  • Maintaining a healthy lifestyle is key to relieving joint discomfort. Regular exercise, such as low-impact sports like walking, cycling, or swimming, should be combined with a well-balanced diet. Aim for 7-8 hours of sleep per night to assist your body in repairing and rebuilding tissue.
  • Applying heat or cold packs to the affected joint can help reduce pain and inflammation.
  • Please track when joint pain occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • If your joint pain is severe or prolonged, consult a doctor to rule out any underlying disorders that may require treatment.
Managing depression as a side effect of medication: a comprehensive guide.
  • Remember, managing depression as a side effect of medication requires patience, persistence, and collaboration with your healthcare team.
  • Tell your doctor about your depression symptoms to adjust medication.
  • Consult a therapist or counsel for emotional support.
  • Engage in regular exercise to release endorphins (neurotransmitters).
  • Practice stress-reducing techniques like meditation and deep breathing.
  • Build a support network of friends, family, and support groups.
  • Establish a consistent sleep schedule.
  • Eat a nutritious diet rich in fruits, vegetables, and whole grains.
  • Limit or avoid alcohol and recreational substances.
  • Keep a mood journal to track symptoms and progress.
Here are the steps to manage the medication-triggered Upper respiratory tract infection:
  • Inform your doctor about the symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids to help loosen and clear mucus from your nose, throat, and airways.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.

Directions for Use

  • Thromplat 25 mg Tablet can be taken on an empty stomach, at least 1 hour before or 2 hours after eating.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow Thromplat 25 mg Tablet as a whole with a glass of water.
  • Do not crush, break, or chew it.

How Thromplat 25 mg Tablet Works

Thromplat 25 mg Tablet works by helping your body produce more platelets, which are small blood cells essential for normal blood clotting. Inside the body, it acts like a natural protein called thrombopoietin (a protein that tells your bone marrow to make more platelets). It binds to and stimulates specific receptors in your bone marrow, which are the factories where blood cells are made. By sending signals to these receptors, Thromplat 25 mg Tablet encourages the bone marrow to grow and mature more cells that eventually become platelets, thereby raising your overall platelet count.
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Alcohol

Caution

Limit alcohol intake, along with Thromplat 25 mg Tablet , to attain the maximum efficacy of Thromplat 25 mg Tablet and rule out any possibility of worsening of side effects.

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Pregnancy

Unsafe

Thromplat 25 mg Tablet is not recommended in pregnancy. It may affect and harm the developing baby. Please consult your doctor if you are pregnant or planning to conceive.

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Breast Feeding

Caution

It is not known if Thromplat 25 mg Tablet is excreted into the breast milk. Please consult your doctor for more information before taking Thromplat 25 mg Tablet if you are a nursing mother.

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Driving

Caution

Thromplat 25 mg Tablet may cause dizziness and tiredness affecting your ability to concentrate and drive. Hence, it is recommended not to drive or operate machinery until you are mentally alert.

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Liver

Caution

Let your doctor know if you have any history of liver diseases before taking Thromplat 25 mg Tablet . Thromplat 25 mg Tablet may cause an increase in liver enzymes. Your doctor may start the treatment with a lower dose of Thromplat 25 mg Tablet .

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Kidney

Consult your doctor

Thromplat 25 mg Tablet should be used with caution in cases of renal impairment. It is advised to seek doctor advice before starting Thromplat 25 mg Tablet if you have any kidney problems.

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Children

Caution

Thromplat 25 mg Tablet is not recommended for children less than one year of age in ITP and children less than two years of age in SAA.

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Heart

Consult your doctor

Please inform your doctor if you have a history of heart disease before using Thromplat 25 mg Tablet . Your doctor will prescribe it only if the benefits outweigh the risks.

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Geriatrics

Safe if prescribed

Thromplat 25 mg Tablet is safe for use in elderly patients if prescribed by the physician.

What if I have taken an overdose of Thromplat 25 mg Tablet

If you take too much of Thromplat 25 mg Tablet , seek immediate medical attention or contact a poison control center right away. An overdose can cause dangerously high platelet counts and increase the risk of serious blood clots.

Diet & Lifestyle Advise

  • Watch your calcium intake timing: Avoid eating calcium-rich foods like yogurt, cheese, milk, or calcium-fortified juices close to your dosing time. Maintain a strict window of 4 hours before or 2 hours after taking the medicine.
  • Avoid certain supplements: Do not take multivitamins, antacids, or supplements containing iron, calcium, magnesium, aluminum, selenium, or zinc within the restricted window, as they bind to the medication and stop its absorption.
  • Keep up with regular blood tests: Attend all scheduled blood tests. Your doctor will usually check your platelet count and liver function before starting treatment and regularly during therapy, often every month or as needed, to make sure the medicine is working safely.
  • Prevent injuries: Because your platelet levels are still being managed, take precautions to avoid cuts, falls, or bruising. Use a soft-bristled toothbrush and a safety razor to lower the risk of bleeding.
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How Soon It Starts Working

The time required for Thromplat 25 mg Tablet to start to work: Thromplat 25 mg Tablet ideally shows its action within 2 to 6 hours after administration. The time for which the effects of Thromplat 25 mg Tablet last: The duration of action for Thromplat 25 mg Tablet is clinically unknown.

What if you forget to take Thromplat 25 mg Tablet

If you miss a dose, do not take a double dose to make up for it. Wait and take your next regularly scheduled dose at your normal time.

Storage

•Store Thromplat 25 mg Tablet tablets at room temperature, between 20°C to 25°C (68°F to 77°F). •Keep the medication in its original packaging to protect it from moisture and light. Do not store it in the bathroom or damp areas.

Drug Warnings

  • Inspect the medicine before use: Always check that you have the correct strength of Thromplat 25 mg Tablet before taking your dose.
  • Do not stop treatment abruptly: Do not stop taking Thromplat 25 mg Tablet suddenly, as your platelet count may fall rapidly and increase the risk of serious bleeding. Your doctor will advise you if treatment should be stopped and will usually monitor your platelet counts for about 4 weeks after discontinuation.
  • Report vision changes promptly: Contact your doctor immediately if you notice blurred vision or any other changes in your eyesight, as Thromplat 25 mg Tablet may increase the risk of cataracts.
  • Inform healthcare providers before procedures: Tell your doctor, dentist, or surgeon that you are taking Thromplat 25 mg Tablet before undergoing any medical, surgical, or dental procedure.

Drug-Drug Interactions

verifiedApollotooltip
  • Antacids and mineral supplements (e.g., aluminium, magnesium, calcium, iron, or zinc): These products may significantly reduce the absorption of Thromplat 25 mg Tablet . Take Thromplat 25 mg Tablet at least 2 hours before or 4 hours after these products.
  • Cholesterol-lowering medicines (e.g., statins): Taking these alongside Thromplat 25 mg Tablet may increase statin levels in the body, raising the risk of muscle pain or muscle damage.
  • Blood thinners (e.g., warfarin, aspirin): Combining these with Thromplat 25 mg Tablet may affect your bleeding risk and require closer monitoring by your doctor.
EltrombopagFerric maltol
Critical
EltrombopagFerrous gluconate
Critical

Drug-Drug Interactions

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EltrombopagFerric maltol
Critical
How does the drug interact with Thromplat 25 mg Tablet:
Ferric maltol can make Thromplat 25 mg Tablet less effective by reducing its absorption and lowering its concentration in the blood. This can lead to poor treatment outcomes.

How to manage the interaction:
Taking Ferric maltol with Thromplat 25 mg Tablet is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. You should take Thromplat 25 mg Tablet on an empty stomach at least 2 hours before or 4 hours after ferric maltol. Do not discontinue any medication without consulting a doctor.
EltrombopagFerrous gluconate
Critical
How does the drug interact with Thromplat 25 mg Tablet:
Ferrous gluconate can make Thromplat 25 mg Tablet less effective by reducing its absorption in the body. This can lead to low treatment outcomes.

How to manage the interaction:
Taking Thromplat 25 mg Tablet with Ferrous gluconate is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. You should take Thromplat 25 mg Tablet on an empty stomach at least 2 hours before or 4 hours after ferrous gluconate. Do not discontinue any medication without consulting a doctor.
EltrombopagAluminium hydroxide
Critical
How does the drug interact with Thromplat 25 mg Tablet:
Coadministration of Thromplat 25 mg Tablet and aluminum hydroxide may interfere with the absorption of Thromplat 25 mg Tablet and reduce its effectiveness.

How to manage the interaction:
Taking Thromplat 25 mg Tablet with aluminum hydroxide is not recommended as it can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without first talking to your doctor.
EltrombopagMagnesium oxide
Critical
How does the drug interact with Thromplat 25 mg Tablet:
Coadministration of Magnesium oxide with Thromplat 25 mg Tablet can impair the absorption of Thromplat 25 mg Tablet which leads to increased levels in the blood. This can increase the risk and severity of side effects.

How to manage the interaction:
Taking Magnesium oxide with Thromplat 25 mg Tablet together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any body aches or pain, chills, cough, difficulty in breathing, fever, headache, or loss of voice you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
EltrombopagCalcium chloride
Critical
How does the drug interact with Thromplat 25 mg Tablet:
When Thromplat 25 mg Tablet is mixed with Calcium chloride, the amount of Thromplat 25 mg Tablet in the blood can decrease. This can lead to low treatment outcomes.

How to manage the interaction:
Taking Thromplat 25 mg Tablet with calcium chloride is not recommended as it can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without talking to your doctor.
EltrombopagMagnesium citrate
Critical
How does the drug interact with Thromplat 25 mg Tablet:
Taking magnesium citrate with Thromplat 25 mg Tablet can make it less effective by reducing its absorption and lowering its concentration in the blood.

How to manage the interaction:
Taking Magnesium citrate with Thromplat 25 mg Tablet is not recommended as it can result in an interaction. It can be taken if your doctor has advised it. You should take Thromplat 25 mg Tablet on an empty stomach at least 2 hours before or 4 hours after magnesium citrate. Do not discontinue any medication without consulting a doctor.
EltrombopagLomitapide
Severe
How does the drug interact with Thromplat 25 mg Tablet:
Coadministration of Thromplat 25 mg Tablet and Lomitapide can increase the risk or severity of liver disease.

How to manage the interaction:
There may be a possibility of interaction between Thromplat 25 mg Tablet and Lomitapide, but it can be taken if prescribed by a doctor. If you have any of these symptoms, it's important to contact a doctor right away: fever, chills, joint pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, bleeding, nausea, vomiting, abdominal pain, dark urine, or liver damage. Do not discontinue any medications without consulting a doctor.
EltrombopagPazopanib
Severe
How does the drug interact with Thromplat 25 mg Tablet:
When Pazopanib and Thromplat 25 mg Tablet are taken together, the body's ability to break down Pazopanib may be reduced. This increases the risk or severity of side effects.

How to manage the interaction:
Taking Thromplat 25 mg Tablet with Pazopanib together can result in an interaction, but it can be taken if your doctor has advised it. If you are having any of these symptoms like irregular heart rhythm, bleeding, fever, chills, joint pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark-colored urine, bleeding, sudden dizziness, lightheadedness, fainting, fast or pounding heartbeats, chest pain, pain in your arms, back, neck, shortness of breath, numbness, weakness on one side of your body, slurred speech or difficulty speaking, make sure to contact a doctor right away. Do not discontinue any medications without consulting a doctor.
EltrombopagTeriflunomide
Severe
How does the drug interact with Thromplat 25 mg Tablet:
Coadministration of Thromplat 25 mg Tablet with Teriflunomide can increase the risk or severity of liver damage.

How to manage the interaction:
Co-administration of Thromplat 25 mg Tablet with Teriflunomide can result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms like fever, chills, joint pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, bleeding, dark colored urine, it's important to contact a doctor right away. Do not discontinue any medications without consulting a doctor.
EltrombopagInterferon alfacon-1
Severe
How does the drug interact with Thromplat 25 mg Tablet:
Coadministration of Thromplat 25 mg Tablet and Interferon alfacon-1 can increase the risk or severity of liver damage.

How to manage the interaction:
Although taking Thromplat 25 mg Tablet and Interferon alfacon-1 together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you have any of these symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark colored urine, light colored stools, and/or yellowing of the skin or eyes, it's important to call a doctor right away. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
  • Calcium-rich foods and dairy products (e.g., milk, cheese, yoghurt, calcium-fortified juices): These foods can reduce the absorption of Thromplat 25 mg Tablet . Avoid consuming them within 4 hours before or 2 hours after taking your dose.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[PLATELET STIMULATING AGENTS]

FAQs

Thromplat 25 mg Tablet is used to treat low blood platelet count in patients with idiopathic thrombocytopenic purpura (ITP) and hepatitis C virus (HCV) infections. It is also used to treat severe aplastic anemia (SAA) in adults.
Thromplat 25 mg Tablet contains Eltrombopag that stimulates platelet's production (helps in clotting) from megakaryocytes (bone marrow cells). Thus Thromplat 25 mg Tablet lowers the risk of bleeding episodes in diseases like immune (idiopathic) thrombocytopenic purpura (ITP), hepatitis C virus (HCV) infections and severe aplastic anaemia (SAA).
Do not stop using Thromplat 25 mg Tablet even if you feel better. It should be strictly used as advised by your doctor to avoid the recurrence of symptoms and worsening of the disease.
Thromplat 25 mg Tablet should be used with caution and only under doctor's supervision in cases of any allergic reactions, blood clots, clotting disorders (Factor V Leiden), blood disorders like blood cancer, myelodysplastic syndrome, cataracts, liver or kidney diseases.
Thromplat 25 mg Tablet decreases the risk of bleeding by increasing the platelet count in your body. However, you are advised to stay away from activities that may increase your risk of bleeding like contact sports and using sharp objects like razors and nail cutters.
It is advised to take Thromplat 25 mg Tablet on an empty stomach. Please take Thromplat 25 mg Tablet at least two hours before or four hours after consuming antacids, mineral and vitamin supplements (iron, calcium, magnesium, aluminium, selenium and zinc), dairy products, calcium-enriched foods and fortified juices since they interfere with the absorption of Thromplat 25 mg Tablet .
Thromplat 25 mg Tablet should be swallowed whole. Do not chew or crush the tablets.
It is usually taken once a day on an empty stomach, at least 1 hour before or 2 hours after eating. Take Thromplat 25 mg Tablet at around the same time every day.
It may take up to 2 weeks for patients to respond to Thromplat 25 mg Tablet .
Thromplat 25 mg Tablet should not be taken with foods, beverages, or other medicines that contain high concentrations of aluminium, calcium, iron, magnesium, selenium and zinc.
Thromplat 25 mg Tablet should be stored in a cool and dry place away from sunlight. Keep out of sight and reach of children.
Thromplat 25 mg Tablet can cause or increase the risk of severe liver issues. Check with your doctor straight away if you or your child experience nausea or vomiting, dark urine, light-coloured stools, right upper stomach pain, unusual exhaustion, or yellow eyes or skin while taking this medication.
Please take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and go back to your regular dosing schedule.
No, Thromplat 25 mg Tablet does not cure these conditions. Instead, it helps manage them by stimulating platelet production and keeping your blood counts in a safer range. Talk to your doctor or pharmacist about long-term management of your condition.
Thromplat 25 mg Tablet may not be recommended during pregnancy or breastfeeding as it could harm the baby. You should discuss the risks and benefits thoroughly with your healthcare provider. Talk to your doctor or pharmacist if you are pregnant or planning to become pregnant.

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Country of origin

India

Manufacturer/Marketer address

S-40, 2Nd Floor, Janta Market, Rajouri Garden, New Delhi - 110 027. India
Other Info - THR0194

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