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compositionComposition:LEVOTHYROXINE SODIUM-12.5MCG
prescription
Prescription Medicine
info
Thyroloc 12.5 mcg Tablet 120's

Thyroloc 12.5 mcg Tablet is used for the treatment of hypothyroidism or low secretion of thyroid hormone. It contains Levothyroxine sodium, which works by replacing the body's normally produced thyroid hormone. It minimises symptoms of low thyroid hormone-like unknown weight gain, fatigue, and sensitivity to the cold. It may cause side effects like headache, weight loss, diarrhoea, irritability and nervousness. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Composition :

LEVOTHYROXINE SODIUM-12.5MCG

Manufacturer/Marketer :

Sanatra Healthcare Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Thyroloc 12.5 mcg Tablet

Thyroloc 12.5 mcg Tablet is a prescription thyroid hormone replacement used to treat hypothyroidism, a condition where the thyroid gland does not produce enough thyroid hormone. 
It replaces the thyroid hormone your body is unable to produce in sufficient amounts, helping restore normal thyroid hormone levels and supporting healthy metabolism, energy production, and organ function.

For this medication to work effectively, you must take it consistently every single day at the same time. It is best taken on an empty stomach with a full glass of water, ideally 30 to 60 minutes before your first meal or caffeinated beverage. Making specific adjustments to your daily routine, such as spacing out when you consume dietary fibre or calcium, can significantly improve how well your body processes the medicine.

While most people tolerate this medicine well, some may experience mild side effects as the body adjusts to the hormone levels. It is important to monitor how you feel and consult your doctor immediately if you experience severe symptoms like a rapid heart rate, chest pain, or extreme sweating. Your doctor will perform routine blood tests to ensure you are receiving the correct amount of hormone.

Talk to your doctor before starting Thyroloc 12.5 mcg Tablet if you have a history of heart disease, high blood pressure, clotting disorders, or diabetes. Do not take this if you have an untreated adrenal gland disorder, an overactive thyroid, or are experiencing symptoms of an acute heart attack. Your doctor will evaluate your thyroid levels and overall health before prescribing this medicine.

This medicine can interact with several common dietary supplements, other medications, and foods, which can reduce its effectiveness. For example, calcium, iron, and certain antacids can block your body from absorbing the medicine. If you are pregnant, breastfeeding, or an older adult, talk to your doctor or pharmacist, as your dosage needs may change or require closer monitoring.
 

Uses of Thyroloc 12.5 mcg Tablet

Thyroloc 12.5 mcg Tablet is used to treat Thyroid. The detailed uses of Thyroloc 12.5 mcg Tablet are as follows:

  • Underactive thyroid (hypothyroidism): Thyroloc 12.5 mcg Tablet replaces the thyroid hormone your body is missing, helping to restore normal metabolic function, energy levels, and body temperature.
  • Thyroid gland enlargement (goitre): It helps shrink or prevent the growth of an enlarged thyroid gland by reducing the levels of thyroid-stimulating hormone in the body.
  • Thyroid cancer management: It is used in combination with surgery or radioactive iodine therapy to help suppress the growth of cancerous thyroid tissue.

Key Benefits

Thyroloc 12.5 mcg Tablet provides thyroid hormone replacement support for people with hypothyroidism by restoring the hormone levels needed for normal body function. By helping maintain balanced thyroid activity, this medicine offers several key health benefits:

  • Improved Energy and Reduced Fatigue: Thyroloc 12.5 mcg Tablet helps restore normal thyroid hormone levels, which can improve low energy, tiredness, and sluggishness associated with hypothyroidism.
  • Better Metabolism and Temperature Regulation: By supporting normal metabolic activity, Thyroloc 12.5 mcg Tablet helps regulate body temperature and improve the body’s ability to use energy effectively.
  • Relief from Hypothyroidism Symptoms: Thyroloc 12.5 mcg Tablet helps reduce symptoms such as constipation, dry skin, hair thinning, and increased sensitivity to cold caused by low thyroid hormone levels.
  • Improved Concentration and Mood: Maintaining adequate thyroid hormone levels with Thyroloc 12.5 mcg Tablet can support better focus, memory, and emotional well-being.
  • Support for Long-Term Health: When used as prescribed, Thyroloc 12.5 mcg Tablet helps maintain normal cardiovascular, muscular, and metabolic function while reducing the risk of complications associated with untreated or poorly controlled hypothyroidism.
     

Directions for Use

  • Always follow your doctor's exact instructions on how to use Thyroloc 12.5 mcg Tablet . To ensure maximum absorption and safety, follow these steps:
  • Take the tablet first thing in the morning on an empty stomach.
  • Swallow the tablet whole with a full glass of water. Do not chew, crush, or split the tablet unless your doctor or pharmacist advises you to do so.
  • Wait at least 30 to 60 minutes before eating breakfast, drinking coffee, or drinking tea.
  • Avoid taking calcium supplements, iron supplements, or antacids within 4 hours of taking your dose, as they can stop the medicinefrom working.

How Thyroloc 12.5 mcg Tablet Works

Thyroloc 12.5 mcg Tablet contains levothyroxine sodium. The thyroid gland naturally produces hormones called thyroxine (T4) and triiodothyronine (T3), which regulate metabolism, energy production, body temperature, and many other bodily functions. Thyroloc 12.5 mcg Tablet contains levothyroxine, a synthetic form of thyroxine (T4) that is identical to the hormone naturally produced by the thyroid gland. After absorption, part of the T4 is converted by the body into triiodothyronine (T3), the more biologically active thyroid hormone. These hormones bind to receptors throughout the body and help regulate cellular activity, energy production, growth, and organ function. By restoring normal thyroid hormone levels, Thyroloc 12.5 mcg Tablet helps normalise metabolism and relieve symptoms of hypothyroidism.
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Alcohol

Caution

You are recommended not to consume alcohol along with Thyroloc 12.5 mcg Tablet to avoid unpleasant side-effects.

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Pregnancy

Safe if prescribed

Only consume Thyroloc 12.5 mcg Tablet , if you are prescribed by a doctor. However, the need for levothyroxine may increase during pregnancy due to increased blood levels of oestrogen (female sex hormone) hence, monitoring of thyroid function should be done regularly both during and after pregnancy. In this case, thyroid hormone dose can be adjusted by your doctor.

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Breast Feeding

Safe if prescribed

Even during high dose levothyroxine therapy, the amount of Thyroloc 12.5 mcg Tablet passing into the breast milk during lactation is very low and therefore harmless. However, if you have any doubt consult a doctor.

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Driving

Safe if prescribed

Thyroloc 12.5 mcg Tablet does not interfere with your ability to drive.

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Liver

Safe if prescribed

Thyroloc 12.5 mcg Tablet can be taken in the prescribed dose as it does not affect the liver.

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Kidney

Caution

Thyroloc 12.5 mcg Tablet can be taken in the prescribed dose as it does not affects the kidney. However patient with adrenal gland complication or problem should consult a doctor before its intake.

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Children

Safe if prescribed

Thyroloc 12.5 mcg Tablet can be given to the children (new-borns and infants) with inborn thyroid hormone deficiency. To achieve normal mental and physical development. The doctor would adjust the dose individually according to the thyroid hormone level and TSH values measured in blood.

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Heart

Caution

Thyroloc 12.5 mcg Tablet can be taken with heart problems, but it should be started at a low dose and monitored closely.

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Geriatrics

Caution

Thyroloc 12.5 mcg Tablet can be taken by geriatric patients, but it requires extra caution due to age-related heart and vascular risks. Doctors usually start with a lower dose and monitor closely to avoid complications like arrhythmia or cardiac ischemia.

What if I have taken an overdose of Thyroloc 12.5 mcg Tablet

Do not take more than the prescribed dose of Thyroloc 12.5 mcg Tablet as it may cause overdose. The symptoms of overdose include confusion, loss of consciousness, seizures (fits), and fast/pounding/irregular heartbeat. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

  • Separate your supplements: Do not take calcium, iron, or multivitamins containing minerals at the same time as your thyroid medicine. Keep them separated by at least 4 hours.
  • Be consistent with soy and fibre: High-fibre diets, soy products, and walnuts can reduce how much medicine your body absorbs. You do not need to avoid these foods completely, but keep your intake consistent and do not eat them close to your dosing time.
  • Delay your morning coffee: Avoid drinking coffee or caffeinated tea for at least one hour after taking Thyroloc 12.5 mcg Tablet , as caffeine significantly interferes with its absorption.
  • Keep a symptom diary: Track your energy levels, sleep patterns, and weight. This information, along with regular blood tests, will help your doctor ensure your dose remains correct.
     

Have a query?

How Soon It Starts Working

The time required for Thyroloc 12.5 mcg Tablet to start to work: The time required for Thyroloc 12.5 mcg Tablet to show its action is unknown. The time for which the effects of Thyroloc 12.5 mcg Tablet last: The duration of action for Thyroloc 12.5 mcg Tablet is unknown.

What if you forget to take Thyroloc 12.5 mcg Tablet

If you miss a dose, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and take the next dose at the scheduled time. Do not take a double dose.

Storage

•Store Thyroloc 12.5 mcg Tablet at room temperature, ideally between 68°F and 77°F (20°C to 25°C). • Keep the tablets in their original container to protect them from moisture and direct light.

Drug Warnings

  • Take this medicine at the same time every day to maintain a steady level of thyroid hormone in your body.
  • Do not use this medicine as a treatment for weight loss or obesity. Taking high doses of thyroid hormone for weight control is dangerous and can cause life-threatening heart issues.
  • Do not switch between different brands or generic versions of this medicine without consulting your doctor first, as even tiny differences can affect your thyroid levels.
  • Expect to have regular blood tests, especially when first starting this medicine or after your doctor has made a change to your daily dose.
  • Be patient with your treatment. It may take several weeks before you start feeling better and noticing a relief in your symptoms.

Drug-Drug Interactions

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Drug-Drug Interactions:

Inform your doctor if you are taking any of the following medicines, as they may interact.

  • Calcium carbonate and ferrous sulfate (iron): These can bind to Thyroloc 12.5 mcg Tablet in your stomach, preventing your body from absorbing it. Space these supplements at least 4 hours apart from your dose.
  • Antacids (containing aluminium or magnesium) and sucralfate: These can decrease the absorption of your thyroid medicine. Space them at least 4 hours apart.
  • Blood thinners (like warfarin): Thyroloc 12.5 mcg Tablet may increase the effects of blood thinners, which can increase your risk of bleeding. Your doctor may need to adjust your blood thinner dose.
  • Diabetes medicines (insulin and oral tablets): This medicine can change your blood sugar levels, meaning your doctor may need to adjust your diabetes medication doses.


Drug-Food Interactions:

Soybean flour, walnuts, and high-fibre foods: Eating these foods close to your dose can significantly decrease the amount of medicine your body absorbs.

  • Coffee and espresso: Consuming caffeine within an hour of taking your medicine can reduce its absorption and effectiveness.
  • Grapefruit juice: This can delay or reduce how well your body processes the medicine.


Drug-Disease Interactions:

Inform your doctor if you have a history of the following conditions before taking Thyroloc 12.5 mcg Tablet , as it may worsen your condition or cause complications.

  • Heart disease or high blood pressure: This medicine can increase your heart rate and put extra stress on your cardiovascular system. Your doctor will monitor you closely and may start you on a very low dose.
  • Untreated adrenal insufficiency: Do not take this medicine if you have untreated adrenal gland issues, as it can trigger a sudden and serious adrenal crisis.
  • Diabetes: This medicine can raise blood sugar levels, requiring you to monitor your glucose levels more closely.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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LEVOTHYROXINE SODIUM-12.5MCGCalcium rich foods
Moderate

Drug-Food Interactions

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LEVOTHYROXINE SODIUM-12.5MCGCalcium rich foods
Moderate
Common Foods to Avoid:
Tofu Set With Calcium, Ragi, Seasame Seeds, Kale, Milk, Almonds, Bok Choy, Calcium-Fortified Soy Milk, Cheese, Yogurt

How to manage the interaction:
Consumption of calcium supplements/calcium-rich foods, along with Thyroloc 12.5 mcg Tablet may create an insoluble compound that affects the absorption of Thyroloc 12.5 mcg Tablet. Avoid consumption of calcium supplements/calcium-rich foods during treatment with Thyroloc 12.5 mcg Tablet.

All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[THYROID AND ANTITHYROID AGENTS]

FAQs

Thyroloc 12.5 mcg Tablet is indicated for the treatment of hypothyroidism or low secretion of thyroid hormone. It works by replacing the body's normally produced thyroid hormone.
No. Thyroloc 12.5 mcg Tablet is only indicated for hypothyroidism and not for weight loss.
No. Thyroloc 12.5 mcg Tablet should be not be taken with food. Please take it empty stomach at least half an hour before tea/coffee/breakfast in the morning.
If you observe symptoms like sudden weight gain, fatigue, increased sensitivity to cold, dry skin, constipation, puffy face, muscle weakness, anxiety or voice hoarseness. You should consult an Endocrinologist/Physician for further treatment.
Your thyroid hormone may vary depending on your age, sex, and condition (like pregnancy, chronic condition or complication). For example, a 30-year-old woman may have normal TSH around 4.2 mU/L, while a 90-year-old man may reach 8.9 mU/L at their upper limits. Besides this, your level of stress, diet, and medications and menses period can fluctuate your level of thyroid hormone.
Yes. Limit salt intake less than 2300 mg daily. Too much salt intake can increase your blood pressure especially when you have an underactive thyroid.
Yes. Based on the thyroid profile test, an Endocrinologist may advise a pregnant woman to take a high dose of Thyroloc 12.5 mcg Tablet to meet the high-level thyroid hormone requirement. Treatment of underactive thyroid is vital during pregnancy, as low levels of thyroid hormone in the mother may harm both mother and baby.
A TSH test can be done once a year in case of hypothyroidism or under active thyroid to check whether your thyroid hormone levels are in normal range or not.
Do not take double doses in case you missed the dose of Thyroloc 12.5 mcg Tablet . If accidentally you have taken too much of Thyroloc 12.5 mcg Tablet , it may cause side effects like nervousness, insomnia, mild elevation of temperature, blood pressure elevation or loose stools. In this case immediately contact the doctor and take only when your doctor has allowed to take it.
Pregnant women with uncontrolled hypothyroidism or underactive thyroid can get low haemoglobin (anaemia), high blood pressure, muscle pain and weakness. Besides this, it can also cause an increased risk of miscarriage, premature birth (before 37 weeks of pregnancy) or even stillbirth. Also, untreated hypothyroidism during pregnancy can cause hypothyroid even in the baby. So, it is advisable to consult an endocrinologist if you are diagnosed with hypothyroidism.
Hair loss may occur during the first few months of treatment. This effect is usually temporary as your body adjusts to this medication. If this effect persists or worsens, tell your doctor for further treatment.
Long term use of Thyroloc 12.5 mcg Tablet may cause decreases bone mineral density. Consult your doctor for further advice.
Take Thyroloc 12.5 mcg Tablet preferably 30 minutes before breakfast, to ensure the best absorption. Always follow your doctor’s instructions and do not exceed the recommended dose.
You are recommended not to stop Thyroloc 12.5 mcg Tablet on your own as it may cause symptoms to worsen and may lead to failure of the treatment in the future.
You are recommended to take the advice of a doctor if you are taking other medications, as it can impact the absorption or effectiveness of Thyroloc 12.5 mcg Tablet . Inform your doctor about all medicines you are currently taking before you start taking Thyroloc 12.5 mcg Tablet to avoid possible interactions
You are recommended to take Thyroloc 12.5 mcg Tablet as long as your doctor advises, as it is typically prescribed for long-term use and may need to be taken for lifelong. Do not stop the medication, as symptoms of low thyroid hormone levels may return.
Thyroloc 12.5 mcg Tablet can be given to children only if advised by the doctor. Do not give Thyroloc 12.5 mcg Tablet to your child on your own.
Thyroloc 12.5 mcg Tablet should be taken as advised by the doctor. Swallow it as whole with a glass of water. Do not crush or chew it.
People with diabetes who take Thyroloc 12.5 mcg Tablet may experience increased blood sugar levels, potentially requiring higher doses of antidiabetic medications or insulin. Therefore, it is advised that they consult a doctor and closely monitor their blood glucose levels when starting, changing, or stopping thyroid hormone treatment.
Thyroxine (T4) is a thyroid hormone that regulates metabolism, energy, and growth. It plays a key role in regulating body weight, internal temperature, energy levels, metabolism, hair, skin and nail growth. Also, it is important for brain development, heart and muscle function, and maintenance of bones. Balanced levels are important, as low levels can cause fatigue and weight gain, while high levels can lead to anxiety and heart issues.
Oral contraceptives containing estrogen and progesterone may lower the levels of Thyroloc 12.5 mcg Tablet in your body, potentially requiring an increase in your Thyroloc 12.5 mcg Tablet dose to maintain effective thyroid hormone levels.
Thyroloc 12.5 mcg Tablet includes side effects such as muscle spasms, headache, nervousness, irritability, sleeplessness, tremors, muscle weakness, weight loss, diarrhoea. These do not require any medical treatment as they will gradually reduce over time. However, please consult the doctor if side effects persist longer.
No, you should not take Thyroloc 12.5 mcg Tablet with coffee. Caffeine can significantly lower the amount of medicine your body absorbs, making it less effective. You should wait at least 60 minutes after taking your tablet before having your morning coffee or tea. Talk to your doctor or pharmacist if you need help adjusting your morning schedule.
While the medicine begins working in your body immediately, it can take several weeks of daily use before you start noticing an improvement in your symptoms, such as increased energy or skin health. Your doctor will check your blood levels after 6 to 8 weeks to determine if your dose needs adjusting. Talk to your doctor if your symptoms do not improve after a few weeks.
Yes, it is safe and highly important to continue taking Thyroloc 12.5 mcg Tablet during pregnancy to support both your health and your baby's development. Your thyroid hormone needs will likely increase during pregnancy, so your doctor will perform frequent blood tests to adjust your dose. Talk to your doctor as soon as you find out you are pregnant.
Yes, some patients can take this medicine at bedtime, but it must be taken on an empty stomach at least 3 to 4 hours after your last meal or snack. The most important factor is consistency; you must take it the same way every day. Talk to your doctor or pharmacist before changing your dosing schedule.
Your body requires a very precise balance of thyroid hormone. Regular blood tests allow your doctor to measure your hormone levels and ensure your dose is neither too high, which can stress your heart and bones, nor too low, which can cause your symptoms to return. Talk to your doctor about how often you should have your blood checked.
If you gained weight due to an underactive thyroid, taking Thyroloc 12.5 mcg Tablet can help return your metabolism to normal, which may lead to some weight loss. However, you must never use this medication as a general weight loss aid, as taking too much can cause serious heart complications. Talk to your doctor if you have concerns about your weight.
Some people may notice mild, temporary hair loss during the first few months of treatment as the body adjusts to changing thyroid hormone levels. This effect can occur in both adults and children and is usually temporary. Hair growth typically returns to normal as hormone levels stabilise. If the hair loss is severe, persistent, or worsening, speak with your doctor, as it may indicate that your thyroid levels need further evaluation or adjustment.
It is highly recommended that you stay on the exact same brand or generic version of this medicine. Even minor differences in manufacturing can affect how your body absorbs the hormone. If your pharmacist switches your version, your doctor may want to test your blood within a few weeks to ensure your levels stay stable. Talk to your doctor or pharmacist before changing your medication brand.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Electronic Medicines Compendium (EMC). Product Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026] Check here
  2. Drugs.com Clinical Review Team. Levothyroxine Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026] Check here
  3. Eltroxin 100mcg tablets - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2021 [Accessed on 26 April 2021] Check here
  4. Eltroxin 100mcg tablets - Patient Information Leaflet (PIL) - (emc) [Internet]. Medicines.org.uk. 2021 [Accessed on 26 April 2021] Check here
  5. LEVO-T [Internet]. Accessdata.fda.gov. 2021 [Accessed on 26 April 2021] Check here
  6. Levothyroxine [Internet]. Ncbi.nlm.nih.gov. 2021 [Accessed on 26 April 2021] Check here
  7. Eghtedari B, Correa R. Levothyroxine. [Updated 2023 Aug 28]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; [Accessed on 13 Feb 2025]Check here

Country of origin

India

Manufacturer/Marketer address

83/4 Friends Colony, Ballupur Distt. Dehradun 248001, Uttarakhand
Other Info - THY0314

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