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compositionComposition:EPLERENONE-25MG+TORASEMIDE-10MG
prescription
Prescription Medicine
info
Tide E 10 Combi Kit Tablet 1's
Tide E 10 Combi Kit Tablet 1's
Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

EPLERENONE-25MG+TORASEMIDE-10MG

Manufacturer/Marketer :

Torrent Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Tide E 10 Combi Kit Tablet

Tide E 10 Combi Kit Tablet is a prescription oral medicine used to reduce swelling and fluid retention (oedema) caused by conditions like heart failure, liver disease, or kidney disease. By helping your body get rid of extra water, it helps relieve strain on your heart and blood vessels. This medication is essential for managing chronic fluid buildup and improving your overall comfort.

It is typically taken once daily, preferably in the morning to prevent middle-of-the-night bathroom trips. You can take this medicine with or without food, but keeping your schedule consistent is key to maintaining steady levels in your body. Making dietary changes, such as reducing your daily sodium intake and staying active within safe limits, can significantly improve your results.

While taking Tide E 10 Combi Kit Tablet, you may experience common, mild side effects such as increased urination, mild dizziness, or an upset stomach. However, you must contact your doctor immediately if you notice serious symptoms like muscle weakness, an irregular heartbeat, severe dizziness, or signs of kidney issues. Regular monitoring of your blood pressure and mineral levels is a standard safety measure during treatment.

Talk to your doctor before starting this medicine if you have a history of kidney disease, liver problems, or diabetes. Do not take this medicine if you have high potassium levels in your blood, severe kidney failure, or if you cannot pass urine. It is critical to share your complete medical history to prevent serious complications.

This medicine can interact with alcohol, which may worsen dizziness, as well as blood pressure drugs, potassium supplements, and certain pain relievers. If you are pregnant, breastfeeding, or planning a pregnancy, or if you are an older adult, consult your doctor or pharmacist before starting Tide E 10 Combi Kit Tablet to ensure it is safe for your specific situation.
 

Uses of Tide E 10 Combi Kit Tablet

Tide E 10 Combi Kit Tablet is used to reduce swelling and fluid retention (oedema). The detailed uses of Tide E 10 Combi Kit Tablet are as follows:

  • Fluid retention (Oedema): Helps the body eliminate excess water and salt buildup caused by heart, liver, or kidney conditions, reducing painful swelling in the legs, ankles, and abdomen.
  • Heart failure support: Eases the workload on a weakened heart muscle by lowering the volume of fluid circulating through the blood vessels, preventing shortness of breath.
  • Resistant high blood pressure: Under specific medical guidance, this combination may be used in selected patients whose blood pressure remains difficult to control despite standard treatment. Its use for resistant hypertension should be based on individual clinical assessment and may represent a specialised or off-label treatment approach depending on the indication and local prescribing guidance. 
     

Key Benefits

Tide E 10 Combi Kit Tablet helps reduce excess fluid buildup in the body while supporting healthy blood pressure and heart function. By improving fluid balance and maintaining important mineral levels, it helps relieve symptoms associated with fluid retention and supports long-term cardiovascular health.

  • Helps Reduce Swelling and Fluid Retention: By removing excess fluid from the body, Tide E 10 Combi Kit Tablet helps reduce swelling in the legs, ankles, and other tissues. This can improve comfort, mobility, and ease symptoms related to fluid overload.
  • Supports Easier Breathing and Heart Health: By reducing excess fluid and helping maintain stable blood pressure, Tide E 10 Combi Kit Tablet can help relieve breathlessness associated with fluid accumulation and support overall heart function. This may also help lower the risk of heart failure-related complications.
  • Supports Potassium Balance with Monitoring: Unlike some diuretic therapies that can lower potassium levels, the eplerenone component helps reduce potassium loss. While this may help maintain normal muscle and nerve function, it can also increase the risk of high potassium levels (hyperkalaemia). Regular blood tests are therefore essential to ensure potassium levels remain within a safe range. 
     
Side effects of Tide E 10 Combi Kit Tablet
  • Limit fruit intake to two servings a day, choose a low-potassium options like apples and strawberries.
  • Restrict starchy vegetables like potatoes and pumpkin to half a cup daily.
  • Avoid or limit foods like tomato products, high-bran cereals, and salty or sugary snacks.
  • Limit dairy products to 200g of yoghurt or 300ml of milk per day.
  • Reduce salt intake to minimize fluid buildup.
  • Use compression stockings, sleeves, or gloves.
  • Gently massage the affected area towards the heart.
  • Protect the swollen area from injury and keep it clean.
  • Use lotion or cream to keep the skin moisturized.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Drink warm fluids such as warm water with honey, broth, soup or herbal tea to soothe sore throat.
  • Gargle with warm salt water.
  • Suck on lozenges to increase the production of saliva and soothe your throat.
  • Use a humidifier to soothe sore throat as it adds moisture to the air and makes breathing easier.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.

Directions for Use

  • Tide E 10 Combi Kit Tablet can be taken with or without food as advised by a doctor.
  • It should be taken at the same time of the day each time for the best results.
  • Swallow it as a whole with a glass of water.
  • Do not crush, chew, or break it.

How Tide E 10 Combi Kit Tablet Works

Tide E 10 Combi Kit Tablet works by combining two different active medicines that target fluid retention from different angles. This dual action makes it highly effective at removing excess water while protecting your body's essential mineral levels. The first active ingredient, torasemide, is a loop diuretic or 'water pill'. It acts on the kidneys to increase the amount of salt and water filtered out of your blood and into your urine. This action rapidly reduces swelling and lowers blood volume, which takes the pressure off your heart. The second active ingredient, eplerenone, is a mineralocorticoid receptor antagonist. It works by blocking the action of aldosterone, a hormone that promotes sodium and water retention. This helps the body eliminate excess sodium and water while reducing potassium loss. Although this potassium-retaining effect can help counterbalance the potassium loss caused by torasemide, it also increases the risk of hyperkalaemia (high potassium levels). For this reason, regular monitoring of potassium levels is an important part of treatment.
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Alcohol

Caution

You are recommended not to consume alcohol along with Tide E 10 Combi Kit Tablet to avoid unpleasant side effects.

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Pregnancy

Caution

Inform your doctor if you are pregnant or suspect pregnancy. Your doctor will weigh the benefits and potential risks before prescribing Tide E 10 Combi Kit Tablet.

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Breast Feeding

Caution

It is not known if Tide E 10 Combi Kit Tablet passes into breastmilk. So, inform your doctor if you are a nursing mother. Your doctor will weigh the benefits and potential risks before prescribing Tide E 10 Combi Kit Tablet.

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Driving

Caution

Tide E 10 Combi Kit Tablet may cause dizziness and sleepiness. Drive only if you are alert.

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Liver

Caution

Tide E 10 Combi Kit Tablet to be taken with caution, especially if you have a history of Liver diseases/conditions. Your doctor may adjust your dose depending on your current kidney conditions.

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Kidney

Caution

Tide E 10 Combi Kit Tablet to be taken with caution, especially if you have a history of Kidney diseases. Your doctor may adjust your dose depending on your current kidney conditions.

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Children

Unsafe

Tide E 10 Combi Kit Tablet is not recommended for children below 12 years of age.

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Heart

Safe if prescribed

Tide E 10 Combi Kit Tablet can be safely used in cardiac patients with heart failure if prescribed by a physician. Please consult your physician if you have any concerns.

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Geriatrics

Caution

Tide E 10 Combi Kit Tablet should be used in elderly people only if prescribed by the physician. If recommended, careful monitoring of any side effects is advised.

What if I have taken an overdose of Tide E 10 Combi Kit Tablet

In case of an overdose, seek immediate medical attention or contact a poison control center right away. Symptoms of an overdose may include extreme dizziness, fainting, severe weakness, or a very slow or irregular heartbeat.

Diet & Lifestyle Advise

  • Limit your salt intake: Avoid adding extra salt to your meals and stay away from highly processed foods, canned soups, and salty snacks, as salt causes your body to hold onto extra water.
  • Avoid potassium-based salt substitutes: Since this medicine helps your body retain potassium, using salt substitutes that contain potassium chloride can lead to dangerously high potassium levels in your blood.
  • Monitor your daily weight: Weigh yourself every morning at the same time (after using the bathroom and before breakfast). A sudden weight gain of 2 to 3 pounds in a single day, or 5 pounds in a week, can mean your body is retaining fluid, and you should contact your doctor.
  • Stay hydrated safely: Discuss your daily fluid intake limits with your doctor. While you are taking a water pill, drinking too much fluid can worsen swelling, while drinking too little can cause dehydration.
  • Rise slowly from sitting or lying down: To prevent dizziness or fainting caused by a sudden drop in blood pressure, take your time when standing up.
     

Have a query?

How Soon It Starts Working

  • The time required for Tide E 10 Combi Kit Tablet to start to work: The time required for Tide E 10 Combi Kit Tablet to start to work is 1 hour after administration.
  • The time for which the effects of Tide E 10 Combi Kit Tablet last: The duration of action for Tide E 10 Combi Kit Tablet is not clinically established.

What if you forget to take Tide E 10 Combi Kit Tablet

If you miss a dose, take it as soon as you remember. However, if it is already late in the afternoon or close to evening, skip the missed dose and take your next dose the following morning. Do not take a double dose to make up for a missed one, as this can cause a sudden drop in blood pressure or dehydration.

Storage

• Store Tide E 10 Combi Kit Tablet tablets at normal room temperature and protect them from excessive heat, moisture, and direct light.

Drug Warnings

  • Get your blood checked regularly; your doctor will need to run frequent blood tests to check your kidney health and potassium levels.
    Be cautious when driving or operating machinery until you know how this medicine affects you, as it can cause dizziness.
  • Avoid drinking alcohol while taking this medicine, as it can dangerously lower your blood pressure and increase the risk of dizziness and fainting.
  • Do not start taking any new over-the-counter pain medications, such as ibuprofen or naproxen, without asking your doctor first, as these can reduce the effectiveness of your water pill and strain your kidneys.
    Tell any healthcare provider you visit, including your dentist or surgeon, that you are taking Tide E 10 Combi Kit Tablet before you undergo any procedures.
     

Drug-Drug Interactions

verifiedApollotooltip

Drug-Drug Interactions:

  • Potassium supplements or other potassium-retaining water pills: May cause dangerously high blood potassium levels.
  • Nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen: May decrease the effectiveness of Tide E 10 Combi Kit Tablet and increase the risk of kidney damage.
  • ACE inhibitors or ARBs (blood pressure medications): May increase the risk of high potassium levels; close monitoring is required.
  • Lithium: Tide E 10 Combi Kit Tablet can reduce the kidney's ability to clear lithium, leading to toxic levels of lithium in the blood.
  • Strong CYP3A4 inhibitors (such as ketoconazole, clarithromycin): May raise the levels of eplerenone in your body, increasing the risk of side effects.


Drug-Food Interactions:

  • Grapefruit juice: May increase the levels of the medication in your bloodstream, leading to an increased risk of side effects.
  • Salt substitutes containing potassium: Can lead to hyperkalaemia (high blood potassium).

Drug-Disease Interactions:

  • Severe kidney disease: May worsen kidney function or cause dangerous potassium buildup.
  • Liver damage: Changes in fluid balance can trigger serious complications in patients with severe liver disease.
  • Diabetes with kidney problems: Increases the risk of developing dangerously high blood potassium levels.
     
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

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Therapeutic Class

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FAQs

Tide E 10 Combi Kit Tablet is used to treat heart failure after a heart attack, high blood pressure, and oedema (fluid build-up).

Tide E 10 Combi Kit Tablet contains Eplerenone and Torasemide. Eplerenone blocks the hormone aldosterone, preventing fluid retention and maintaining potassium levels. Torasemide removes excess water and salt from the body, reducing swelling and fluid overload. Together, they improve heart function, reduce oedema, and help control blood pressure.

Yes, Tide E 10 Combi Kit Tablet may cause excessive urination. Most people need to pee about 30 minutes after taking Tide E 10 Combi Kit Tablet and again within a few hours. Do not take Tide E 10 Combi Kit Tablet before going to bed, or you may have to wake up at night to go for urination frequently.

Yes, Tide E 10 Combi Kit Tablet is known to cause dehydration (excessive fluid loss). The patient may experience dry mouth, decreased urine output, excessive thirst, and hypotension (decreased blood pressure). Please increase fluid intake to avoid severe dehydration.

Yes, Tide E 10 Combi Kit Tablet can cause increased potassium levels (hyperkalemia), especially in patients with kidney problems or when taken with potassium supplements. Please monitor your electrolyte level regularly to avoid increased blood potassium levels.

Yes, Tide E 10 Combi Kit Tablet may occasionally cause dizziness due to orthostatic hypotension (sudden drop in blood pressure when standing from a lying position) or passing out. To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.

Swallow Tide E 10 Combi Kit Tablet whole with water; do not crush or chew it.

Tide E 10 Combi Kit Tablet should be taken with caution, only if prescribed by a doctor, and only if you have kidney or liver disease. Please consult the doctor if you have any concerns.

Tide E 10 Combi Kit Tablet may cause side effects like headache, dizziness, diarrhoea, constipation, nausea, and excessive urination. Most of these side effects do not require medical attention and resolve over time. However, consult your doctor if the side effects persist or worsen.

Treatment with Tide E 10 Combi Kit Tablet requires regular monitoring of serum potassium, sodium and creatinine levels. Monitor your blood pressure daily, and if there is excessive fluctuation, contact your doctor immediately. Regular monitoring of uric acid in patients with gouty arthritis.

Other medications can be taken with Tide E 10 Combi Kit Tablet only if advised by the doctor. Please consult the doctor before taking any other medicines with Tide E 10 Combi Kit Tablet to avoid interactions.

It is highly recommended to take Tide E 10 Combi Kit Tablet in the morning. Taking it late in the day or at night can cause you to wake up multiple times to urinate, which can disrupt your sleep. If you need to adjust your timing, talk to your doctor.

Because Tide E 10 Combi Kit Tablet contains a potassium-retaining medicine, eating large amounts of high-potassium foods like bananas, oranges, or leafy greens might cause your potassium levels to rise too high. You do not necessarily have to cut them out completely, but you should discuss your diet with your doctor.

Dizziness is a common side effect, especially when you stand up quickly. Try to rise slowly from sitting or lying positions. If the dizziness is severe, makes you feel faint, or does not go away, sit down immediately and talk to your doctor.

It is best to avoid alcohol while taking this medicine. Alcohol can increase the blood pressure-lowering effects of Tide E 10 Combi Kit Tablet, making you feel extremely dizzy, lightheaded, or prone to fainting. Talk to your doctor if you have concerns about alcohol use.

Tide E 10 Combi Kit Tablet is generally not recommended during pregnancy unless your doctor decides the benefits clearly outweigh the risks. This medication can affect fluid levels that are critical for both you and your developing baby. Talk to your doctor if you are pregnant or planning to become pregnant.

You should avoid taking over-the-counter pain relievers like ibuprofen or naproxen without consulting a healthcare professional. These medicines can stop your water pill from working properly and increase the risk of kidney damage. Talk to your doctor or pharmacist for safer pain relief alternatives.

Your doctor will likely schedule blood tests quite frequently when you first start taking the medicine, and then periodically once your dose is stable. These tests are essential to monitor your kidney function and ensure your potassium levels remain in a safe range. Talk to your doctor to understand your specific testing schedule.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Off. Ashram Road, Ahmedabad - 380 009., Gujarat, India.
Other Info - TID0053

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