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compositionComposition:TIGECYCLINE-50MG
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Prescription Medicine
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Tigestat 50mg Injection is used to treat bacterial infections. It contains Tigecycline which works by killing the infection-causing bacteria. In some cases, this medicine may cause side effects such as nausea, vomiting, diarrhoea, and headache. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Dr. Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

TIGECYCLINE-50MG

Manufacturer/Marketer :

Neon Laboratories Ltd

Consume Type :

Parenteral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Tigestat 50mg Injection

Tigestat 50mg Injection is an injection used to treat serious bacterial infections, such as complicated skin infections, severe abdominal infections, and community-acquired pneumonia. It belongs to a group of medicines that work by stopping the growth and spread of bacteria in the body. Because it targets a wide variety of bacteria, it is typically reserved for severe cases where other treatments may not be suitable.

This medication is given directly into a vein as an intravenous infusion, usually once every 12 hours. Since it is given directly into the bloodstream, food intake does not affect how the medicine is absorbed, but staying well-hydrated and eating balanced meals can help support your recovery. It is important to receive this medicine consistently at the times scheduled by your healthcare team to ensure the infection is completely cleared.

While taking Tigestat 50mg Injection, you may experience some common side effects such as nausea, vomiting, or diarrhoea. Most of these are mild, but you must contact your doctor immediately if you experience serious symptoms like severe stomach pain, watery or bloody diarrhoea, or yellowing of your skin or eyes. Your healthcare team will monitor you closely during your treatment to ensure your safety.

Talk to your doctor before starting this medicine if you have a history of liver problems or swelling of the pancreas. Do not take this medicine if you are allergic to this medication or other similar antibiotics. In certain cases, it may be prescribed for children aged 8 years and older to treat serious bacterial infections. It is generally not recommended for children younger than 8 years of age because it may cause permanent tooth discolouration and affect bone development.

This medicine may interact with blood thinners and can make birth control pills less effective. It is also important to tell your doctor if you are pregnant, think you may be pregnant, are planning to become pregnant, or are breastfeeding, as this treatment can cause harm to an unborn baby. Talk to your doctor or pharmacist to understand how your other medicines or health conditions might interact with this treatment.

Being told you need an intravenous (IV) antibiotic in a hospital or healthcare setting can feel overwhelming. Rest assured that your healthcare team will be with you throughout your treatment, monitoring your progress, managing any side effects, and answering any questions you may have to help ensure your care is as safe and comfortable as possible. 

Uses of Tigestat 50mg Injection

Tigestat 50mg Injection is an antibiotic used to treat a range of serious bacterial infections by eliminating the bacteria responsible for the infection and helping the body recover.

  • Complicated skin and skin structure infections: Helps by clearing deep-seated skin infections, preventing the bacteria from spreading further into body tissues.
  • Complicated intra-abdominal infections: Treats complex infections inside the stomach area, such as deep abscesses or appendicitis, by destroying the bacteria causing the swelling.
  • Community-acquired bacterial pneumonia: Helps clear severe lung infections that are caught outside of a hospital, helping to restore normal breathing.
  • Kidney disease: No formal dose adjustment is generally required for people with kidney disease. However, if you have severe kidney impairment or are receiving dialysis, discuss your treatment with your doctor to ensure Tigestat 50mg Injection is appropriate for you. 

Key Benefits

In addition to treating infections, Tigestat 50mg Injection provides the following therapeutic benefits that support the body's recovery process. 

  • Broad-spectrum antibacterial action: Tigestat 50mg Injection provides vital support when standard antibiotics may not be strong enough to fight off certain resistant bacteria. Because it targets a broad spectrum of bacteria, it is highly effective at resolving severe and complex infections, helping your body start the recovery process quickly.
  • Rapid intravenous action: Since this medication is given directly into a vein, it goes to work in your bloodstream immediately. This rapid action helps to reduce symptoms like fever, pain, and inflammation as the infection starts to improve.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Tigestat 50mg Injection will be administered by the doctor or healthcare professional.
  • Do not self-administer.

How Tigestat 50mg Injection Works

Tigestat 50mg Injection contains tigecycline, an antibiotic belonging to the glycylcycline class, which is derived from tetracycline antibiotics (specifically minocycline). It works by entering bacterial cells and blocking their ability to produce essential proteins needed for growth and multiplication. Without these proteins, the bacteria cannot grow or spread, allowing your body's natural immune system to help clear the infection. Before or during treatment, your doctor may order a culture and sensitivity test to identify the bacteria causing the infection and confirm that this antibiotic is appropriate. If you have ever had an allergic reaction to Tigestat 50mg Injection, tetracyclines, or related antibiotics, inform your doctor before starting treatment. If your symptoms do not improve, worsen, or new symptoms develop during treatment, contact your doctor promptly, as your treatment may need to be reassessed.
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Alcohol

Caution

Avoid taking alcohol while using Tigestat 50mg Injection since it may worsen the side effects.

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Pregnancy

Unsafe

Tigestat 50mg Injection is not recommended during pregnancy due to its harmful effects on the baby, including toxic effects on skeletal formation. Please consult your doctor before taking Tigestat 50mg Injection if you are pregnant or planning to conceive.

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Breast Feeding

Caution

It is not known if Tigestat 50mg Injection is excreted into breast milk. Please consult your doctor before taking Tigestat 50mg Injection if you are breastfeeding.

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Driving

Caution

You may experience dizziness as one of the side effects of Tigestat 50mg Injection. In such cases, do not drive or operate machinery until you feel better.

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Liver

Caution

Let your doctor know if you have any history of liver diseases before taking Tigestat 50mg Injection. Tigestat 50mg Injection should be used caution in cases of severe liver disease.

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Kidney

Caution

Let your doctor know if you have any history of kidney diseases before taking Tigestat 50mg Injection. Dose adjustment may be required.

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Children

Caution

Tigestat 50mg Injection is not recommended for children younger than eight years old.

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Heart

Caution

Limited data is available regarding the use of Tigestat 50mg Injection in patients with heart problems. Please consult your doctor if you have any concerns regarding this.

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Geriatrics

Caution

Tigestat 50mg Injection should be administered with caution in elderly patients due to an increased risk of side effects. Seek medical advice if you have any concerns.

What if I have taken an overdose of Tigestat 50mg Injection

Because this medicine is given under medical supervision, an overdose is highly unlikely. If you suspect you have received too much or experience unusual symptoms during or after your infusion, tell your healthcare provider or seek emergency medical help right away.

Diet & Lifestyle Advise

  • Stay hydrated: Drink plenty of water and clear fluids to help your body process the medication and support recovery.
  • Eat a balanced diet: Choose foods rich in vitamins, minerals, and other nutrients to strengthen your immune system and aid healing.
  • Avoid alcohol: Do not consume alcohol while receiving this medication, as it may put additional strain on your liver.
  • Get adequate rest: Ensure you get enough sleep and rest so your body can focus its energy on fighting the infection and recovering.
  • Consider probiotics after treatment: Speak with your doctor about taking a probiotic after completing your treatment to help restore healthy bacteria in your digestive system.
health query

Have a query?

How Soon It Starts Working

The time required for Tigestat 50mg Injection to start to work: The time required for Tigestat 50mg Injection to show its action is unknown. The time for which the effects of Tigestat 50mg Injection last: The duration of action for Tigestat 50mg Injection is clinically unknown.

What if you forget to take Tigestat 50mg Injection

Since this medication is given by a healthcare professional, it is unlikely that you will miss a dose. However, if you miss an appointment or suspect a dose was missed, contact your doctor or clinic immediately to get back on schedule.

Storage

• Store the unmixed dry powder at room temperature between 20°C to 25°C (68°F to 77°F).

Drug Warnings

  • Inspect the solution: Always ensure the solution is yellow to orange in colour and free from floating particles before it is injected.
  • Report infusion site reactions: Tell your healthcare team immediately if you experience pain, burning, coldness, or swelling around the vein during the infusion.
  • Protect your skin from sunlight: This medication may increase your skin's sensitivity to the sun. Wear protective clothing and apply sunscreen when outdoors.
  • Inform your doctor about blood thinners: If you are taking blood-thinning medications, let your doctor know before starting treatment, as closer monitoring of your blood clotting levels may be required.
  • Complete the full course: Never skip doses or stop treatment early, even if you feel better, to help prevent antibiotic resistance.
  • Severe diarrhoea: If you develop severe, watery, or bloody diarrhoea, do not take any over-the-counter anti-diarrhoea medicines. Contact your doctor immediately, as this may be a sign of a serious bowel infection that requires prompt medical attention.
  • Use during pregnancy: Inform your doctor if you are pregnant or planning to become pregnant before starting treatment. Tigestat 50mg Injection can cause harm to an unborn baby and should only be used if clearly needed. 

verifiedApollotooltip

Inform your doctor if you are taking any of the following medicines, as they may interact with Tigestat 50mg Injection:

  • Blood thinners (such as warfarin): May increase the risk of bleeding, requiring your doctor to monitor your blood clotting times more closely.
  • Birth control pills: May decrease the effectiveness of hormonal contraceptives, so you should use an additional barrier method of birth control while receiving this medicine.

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verifiedApollotooltip
  • No clinically significant food interactions are known with Tigestat 50mg Injection when used as directed.

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIBIOTICS]

FAQs

Tigestat 50mg Injection is used to treat bacterial infections like abdominal infections, community-acquired pneumonia (lung infection), and complicated skin and skin structure infections.
Tigestat 50mg Injection contains Tigecycline, a broad-spectrum antibiotic that treats various bacterial infections. It works by inhibiting bacterial protein synthesis, which further inhibits bacterial growth.
Tigestat 50mg Injection can affect live vaccines like typhoid vaccine and decrease their effectiveness. Please consult a doctor before you start Tigestat 50mg Injection if you are undergoing any vaccinations.
Tigestat 50mg Injection can make your skin more sensitive to the harmful effects of sunlight. Hence it is advised to use sunscreen and wear protective clothing while using Tigestat 50mg Injection. It is also recommended to avoid tanning booths and sunlamps.
Diarrhoea can be a side-effect of Tigestat 50mg Injection. Drink enough fluids and eat fibre rich food if you experience diarrhoea. If you find blood in stools (tarry stools) or experience excess diarrhoea, consult your doctor. Do not take anti-diarrhoeal medicine on your own.
Tigestat 50mg Injection will be administered by a healthcare professional; do not self-administer.
Yes, Tigestat 50mg Injection contains Tigecycline which belongs to the glycylcycline class of antibiotics.
Tigestat 50mg Injection starts working within 30-60 minutes. However, it might take a few days to notice its full effects.
Tigestat 50mg Injection may cause side effects like nausea, vomiting, diarrhoea, headache, and abnormal liver function tests. If any of these effects persist or worsen, seek medical advice promptly.
Yes, in some cases, a trained home healthcare nurse can inject this medication at your home. However, your first dose is usually given in a clinic or hospital setting so you can be monitored closely. Talk to your doctor to see if home treatment is appropriate for you.
If you develop severe, watery, or bloody diarrhoea, do not take any over-the-counter anti-diarrhoea medicines. Contact your doctor immediately, as this can be a sign of a serious bowel infection that requires different treatment.
Tigestat 50mg Injection is generally not recommended during pregnancy because it may cause harm to the unborn baby and may affect fetal bone development. If you are pregnant, think you may be pregnant, or are planning to become pregnant, discuss the potential risks and alternative treatment options with your doctor before using this medicine.
It is best to avoid alcohol during your treatment. Both alcohol and this medicine can strain your liver, and drinking alcohol may make side effects like nausea or dizziness worse. Talk to your doctor or pharmacist for personalised advice.
The length of treatment depends entirely on the type and severity of your infection. It typically lasts between 5 to 14 days, but your doctor will decide the exact length based on how your body responds.
No, this medicine is an antibiotic and only works against bacterial infections. It will not cure viral infections like the common cold, flu, or Covid-19.
Tigestat 50mg Injection may be used in adults and, in certain cases, in children aged 8 years and older for the treatment of serious bacterial infections when prescribed by a doctor. It is generally not recommended for children younger than 8 years of age because of the risk of permanent tooth discolouration and effects on bone development.

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Manufacturer/Marketer address

604, Corporate House, Opp. Torrent House, Nr. Dinesh Hall, Ashram Road, Ahmedabad-380 009.
Other Info - TI99135
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