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compositionComposition:GENTAMICIN-40MG
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Prescription Medicine
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Tipgenta 40mg Injection is an antibiotic used in the treatment of bacterial infections of the ear, nose, throat, respiratory tract, gastrointestinal tract, biliary tract, bone and joint, skin and soft tissue. It helps by inhibiting the protein synthesis of the bacterial cell and thereby helps fight infection causing bacteria. This medicine is not effective for treating viral infections.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
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More about the Product

Composition :

GENTAMICIN-40MG

Manufacturer/Marketer :

Tamman Titoe Pharma Pvt Ltd

Consume Type :

Parenteral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Tipgenta 40mg Injection

Tipgenta 40mg Injection is a prescribed injectable antibiotic used to treat serious, life-threatening bacterial infections throughout the body. It is typically prescribed for severe blood, urinary tract, chest, or abdominal infections when other treatments may not be effective. Its main medical purpose is to target and destroy the bacteria causing these severe illnesses.

Because this medicine is injected directly into the body, it is usually given on a highly consistent daily schedule determined by your doctor to maintain steady levels in your blood. It is crucial to complete the entire course of treatment, even if you begin to feel better within a few days. Drinking plenty of fluids during your treatment is a highly helpful lifestyle habit that protects your body while using this medication.

Common side effects of this medication may include mild nausea, poor appetite, or irritation where the injection was given. However, you must contact your doctor immediately if you experience serious symptoms such as changes in your hearing, constant ringing in your ears, severe dizziness, or a sudden drop in how much you urinate.

Before starting treatment, talk to your doctor if you have a history of kidney disease, hearing problems, or nerve-muscle disorders like myasthenia gravis. Do not take this medicine if you have ever had a severe allergic reaction to similar injectable antibiotics.

This medicine can interact with other treatments like strong water pills or other antibiotics, which can increase the risk of kidney or hearing damage. If you are pregnant, breastfeeding, or an elderly individual, consult your doctor as your dosage and kidney health will need very close monitoring.

Uses of Tipgenta 40mg Injection

Your doctor may prescribe Tipgenta 40mg Injection to help manage the following conditions:

  • Severe blood infections (sepsis): It helps eliminate bacteria circulating in the bloodstream to prevent systemic organ damage.
  • Complicated urinary tract infections: It targets and clears deep-seated bacterial infections in the kidneys and bladder.
  • Chest and lung infections: It treats serious bacterial pneumonia when other standard antibiotics are not suitable.
  • Bone and joint infections: It reaches deep tissues to clear stubborn bacterial bone infections and support healing.
  • Abdominal infections: It resolves severe bacterial infections within the stomach and abdominal cavity.

Key Benefits

When used as directed as part of your treatment plan, Tipgenta 40mg Injection may provide the following benefits:

  • Helps treat serious bacterial infections: Helps eliminate susceptible bacteria causing severe infections in different parts of the body.
  • Helps control the spread of infection: Helps prevent the infection from becoming worse or spreading to other organs.
  • Supports recovery from severe infections: Helps treat serious infections affecting the bloodstream, urinary tract, lungs, abdomen, bones, and joints when caused by susceptible bacteria.
  • May relieve infection-related symptoms: As the infection improves, symptoms such as fever, chills, pain, and tiredness may gradually improve.
  • Supports recovery when used with other antibiotics: For some severe infections, your doctor may prescribe this medicine together with other antibiotics to improve treatment.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safe and effective use.
  • Tipgenta 40mg Injection will be administered by the doctor or healthcare professional.
  • Do not self-administer.

How Tipgenta 40mg Injection Works

Tipgenta 40mg Injection contains gentamicin; it belongs to a class of medicines known as aminoglycoside antibiotics (a medicine used to treat bacterial infections). It works by entering bacterial cells and attaching to ribosomes (structures inside bacteria that make proteins). This prevents the bacteria from making the proteins they need to grow, survive, and multiply. As a result, the bacteria die. By killing the bacteria causing the infection, this medicine helps your body's immune system (the body's natural defence against infection) clear the infection. This medicine works only against susceptible bacterial infections. It does not treat viral infections such as the common cold or flu.
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Alcohol

Caution

Limit or avoid alcohol intake while being treated with Tipgenta 40mg Injection since it may worsen side effects like dizziness.

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Pregnancy

Caution

Tipgenta 40mg Injection should be cautiously administered during pregnancy since there are chances of fetal harm. Please consult your doctor before taking Tipgenta 40mg Injection if you are pregnant or planning to conceive.

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Breast Feeding

Caution

Tipgenta 40mg Injection can be excreted into breast milk in small amounts when used by a nursing mother. Please consult your doctor before taking Tipgenta 40mg Injection if you are breastfeeding.

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Driving

Caution

Tipgenta 40mg Injection may cause side effects like dizziness or vertigo that could affect your driving ability. Do not drive or operate machinery in such cases. Drive only when you are mentally alert.

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Liver

Caution

Let your doctor know if you have any history of liver diseases before taking Tipgenta 40mg Injection since it may cause abnormal liver function tests.

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Kidney

Caution

Let your doctor know if you have any history of kidney diseases or impairment before taking Tipgenta 40mg Injection. Dose adjustment may be required.

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Children

Caution

Tipgenta 40mg Injection should be used for children only when prescribed by a doctor. The dose may depend on the child's age and body weight.

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Heart

Caution

Tipgenta 40mg Injection can be used in heart patients, but with caution. It may cause electrolyte imbalances or kidney strain, which can indirectly affect heart function, especially in those with pre-existing cardiac conditions. Always consult your doctor before use to ensure it's safe for your specific heart profile.

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Geriatrics

Caution

Tipgenta 40mg Injection can be used in geriatric patients, but older adults are more susceptible to kidney damage and hearing loss. Doctors typically adjust the dose and monitor kidney function closely to ensure safe use.

What if I have taken an overdose of Tipgenta 40mg Injection

If you suspect you have received too much of this medicine, seek immediate medical attention. An overdose can increase the risk of damage to your kidneys and the nerves that control your hearing and balance.

Diet & Lifestyle Advise

  • Stay well-hydrated: Drink plenty of water throughout the day (unless your doctor advises you to limit fluids) to help your kidneys safely filter and flush the medication from your system.
  • Rest and conserve energy: Allow your body plenty of physical rest to help your immune system fight off the severe infection.
  • Monitor your body's output: Pay attention to the frequency and colour of your urine, and report any sudden changes to your doctor.
  • Avoid sudden movements: If you feel slightly unsteady or dizzy during your treatment course, move slowly and avoid heavy physical activities to prevent falls.
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How Soon It Starts Working

The time required for Tipgenta 40mg Injection to start to work: Tipgenta 40mg Injection ideally shows its action within 30 to 60 minutes after administration. The time for which the effects of Tipgenta 40mg Injection last: The effect of Tipgenta 40mg Injection lasts for 6 to 8 hours.

What if you forget to take Tipgenta 40mg Injection

Because this medication relies on a strict schedule to keep steady levels in your body, you must receive it consistently. If you think you have missed an injection, contact your doctor or clinic immediately for instructions. Do not double the dose to make up for a missed one.

Storage

•Store Tipgenta 40mg Injection vials at controlled room temperature, safely between 20°C and 25°C (68°F to 77°F). •Do not freeze the medicine, and keep it protected from direct sunlight, moisture, and excessive heat.

Drug Warnings

  • Complete the full course: Continue receiving this medicine for the full duration prescribed, even if you start feeling better, unless your doctor tells you to stop.
  • Stay well hydrated: Drink plenty of fluids during treatment, unless your doctor has advised you to limit your fluid intake. This helps support normal kidney function.
  • Watch for hearing changes: Consult your doctor right away if you notice ringing in your ears, hearing loss, dizziness, or problems with balance during treatment.
  • Report kidney-related symptoms: Consult your doctor right away if you notice a decrease in the amount of urine you pass, swelling of your feet or ankles, or unusual tiredness, as these may be signs of kidney problems.
  • Attend follow-up appointments: Keep all scheduled appointments for blood tests so your doctor can monitor your kidney function and, if needed, the level of gentamicin in your blood to help ensure safe treatment.
  • Tell your doctor about other medicines: Inform your doctor about all medicines you are taking, especially medicines that may affect the kidneys or hearing, before and during treatment.
  • Seek help for severe diarrhoea: Consult your doctor right away if you develop severe or persistent diarrhoea during or after treatment, as this could be a sign of a serious bowel infection associated with antibiotic use.
  • Tell your healthcare team about muscle disorders: Before treatment, inform your doctor if you have myasthenia gravis (a condition that causes muscle weakness) or other neuromuscular disorders, as gentamicin may worsen muscle weakness.

verifiedApollotooltip
  • Water pills (loop diuretics like furosemide): May significantly increase the risk of hearing damage and kidney issues when used together.
  • Other strong antibiotics (such as vancomycin or cephalosporins): Can place extra strain on your kidneys and increase the risk of kidney damage.
  • Muscle relaxants (used during surgery): This medicine may prolong or strengthen the effects of muscle relaxants, which can affect your breathing.

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verifiedApollotooltip
  • No clinically significant food interactions are known with Tipgenta 40mg Injection when used as directed.

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Habit Forming

No

Therapeutic Class

[ANTIBIOTICS]

FAQs

Tipgenta 40mg Injection belongs to the class of 'antibiotics', primarily used to treat serious bacterial infections. Bacterial infection occurs when harmful bacteria grow in the body and causes illness.
Tipgenta 40mg Injection is an antibiotic that treats bacterial infections. It works by inhibiting bacterial protein synthesis, which retards bacterial growth.
Tipgenta 40mg Injection should be used with proper caution and doctor consultation if you have any allergic reactions to medicines, liver/kidney problems, cystic fibrosis, hearing problems, low blood minerals/electrolyte imbalance, myasthenia gravis (muscular weakness), and Parkinson's disease.
Tipgenta 40mg Injection can affect the live vaccines like typhoid vaccine and decrease its effectiveness. Please consult a doctor if you are undergoing any vaccinations.
Tipgenta 40mg Injection may cause abnormal liver function tests as one of its side effects. It may increase the levels of liver enzymes and blood bilirubin. Please consult your doctor before starting Tipgenta 40mg Injection if you have any history of liver problems.
Diarrhoea can be a side-effect of Tipgenta 40mg Injection. Clostridium difficile-associated diarrhoea (CDAD) is also reported during usage of antibiotics like Tipgenta 40mg Injection. Therefore, when the patient has diarrhoea, undergoing an examination is advised to rule out the chances of CDAD following Tipgenta 40mg Injection therapy.
This medicine is injected either directly into a large muscle or given slowly into a vein through an intravenous infusion. It is typically administered by a trained healthcare professional. Talk to your doctor if you have questions about how your injections are given.
Yes, this medication can affect kidney function, especially if it is used for a long time or in high doses. Your doctor will monitor your kidney health with regular blood tests during your treatment. Talk to your doctor if you notice you are urinating less than usual.
Ringing in your ears, hearing loss, or dizziness are serious signs that the medicine may be affecting your inner ear nerves. You must contact your doctor immediately if you notice these changes. Talk to your doctor to see if your treatment plan needs to be adjusted.
This medicine is generally not recommended during pregnancy because it can cause harm, including permanent hearing loss, to the unborn baby. It is typically reserved for life-threatening infections when other options cannot be used. Talk to your doctor to discuss the risks and benefits.
Regular blood tests are necessary to measure the exact amount of the medicine in your blood and to check how well your kidneys are working. This helps your doctor keep the dose in a safe and effective range. Talk to your doctor or pharmacist about your blood monitoring schedule.
While alcohol does not directly interact with this medicine, it can cause dehydration, which increases the strain on your kidneys. It is highly recommended to avoid alcohol and focus on staying well-hydrated during your recovery. Talk to your doctor for personalised advice.
No, you must complete the exact course prescribed by your doctor, even if you feel completely recovered. Stopping an antibiotic too early can allow the strongest bacteria to survive, multiply, and become resistant to treatment. Talk to your doctor before making any changes.

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Country of origin

India
Other Info - TI38157
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