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Tizarest 100mg/2mg Tablet is used to relieve pain and inflammation linked to conditions such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, muscle pain, tooth pain, bone and joint pain, and headache. It helps relax tight, stiff muscles, reducing discomfort. Reducing pain and swelling makes movement easier. This helps improve daily activity and overall physical comfort.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
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More about the Product

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Tizarest 100mg/2mg Tablet

Tizarest 100mg/2mg Tablet is a prescription medication used to treat painful muscle spasms associated with various bone, joint, or muscle conditions. It helps reduce muscle stiffness, relieves moderate-to-severe pain, and restores physical mobility. This medication is typically prescribed for short-term relief during acute flare-ups of muscle pain or injury.

To get the best results, you should take it consistently at the exact times recommended by your doctor. It is highly recommended to take this tablet with food or a glass of milk to prevent stomach irritation. Combining this medical treatment with gentle stretching exercises and adequate rest can significantly improve your recovery process.

While taking you might experience mild side effects such as drowsiness, dizziness, or a dry mouth. These symptoms are generally temporary and tend to go away as your body adjusts to the medicine. However, if you experience serious symptoms like yellowing of your skin or eyes, severe stomach pain, or an irregular heartbeat, contact your doctor immediately.

Before starting this medicine, you must tell your doctor if you have a history of liver disease, kidney problems, or stomach ulcers. Do not take this if you have severe liver damage, active bleeding disorders, or if you are currently taking certain antidepressant or blood pressure medications. Talk to your doctor or pharmacist to ensure this medicine is safe for your specific health profile.

Drinking alcohol while taking it can severely increase drowsiness and raise the risk of liver damage, so it must be avoided entirely. If you are pregnant, breastfeeding, or an older adult, consult your doctor before using this medication, as special precautions may be needed. This medicine is generally not recommended for children unless prescribed by a doctor. The safety and appropriate dose should be decided by a healthcare professional. 

Uses of Tizarest 100mg/2mg Tablet

Your doctor may prescribe this medication to manage several musculoskeletal issues. The primary uses include:

  • Painful muscle spasms: Tizarest 100mg/2mg Tablet relaxes tight, cramping muscles and blocks pain pathways, helping you move more comfortably.
  • Lower back pain: It relieves acute, severe back pain caused by muscle strains, injuries, or joint stiffness in the spine.
  • Neck pain and stiffness: This medicine reduces muscle tension in the neck and shoulders, helping restore a normal range of motion.
  • Post-operative pain: It helps manage painful muscle spasms and localised discomfort that can occur after orthopaedic surgeries.

Key Benefits

This medicine brings several key health benefits:

  • Relieves muscle tightness and pain: Tizarest 100mg/2mg Tablet provides dual-action relief by targeting both physical muscle tightness and the accompanying pain.
  • Supports faster recovery: This combined action allows you to recover faster from acute muscle injuries and return to your daily activities with minimal discomfort.
  • Improves movement and sleep: Secondly, by relaxing the affected muscles, this medication helps restore flexibility and physical movement. It also aids in improving your sleep quality, which is often disrupted by painful, night-time muscle spasms.

Directions for Use

  • Tizarest 100mg/2mg Tablet can be taken with food to avoid stomach upset.
  • It is usually taken twice daily or as prescribed by your doctor.
  • Swallow Tizarest 100mg/2mg Tablet as a whole with a glass of water.
  • Do not break, chew, or crush it.

How Tizarest 100mg/2mg Tablet Works

Tizarest 100mg/2mg Tablet contains two active medicines that work together to relieve pain and stiffness. Tizanidine is a central alpha-2 adrenergic agonist that works in the brain and spinal cord to calm overactive nerve signals that cause muscles to tighten. This helps stiff, cramping muscles relax and improves movement. Aceclofenac is a pain-relieving medicine that mainly blocks the COX-2 enzyme, reducing the production of chemicals called prostaglandins that cause pain, swelling, and inflammation. Together, these two medicines help break the cycle of muscle spasm and pain, providing effective relief.
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Tizarest 100mg/2mg Tablet as it may cause increased drowsiness. It may also increase the risk of stomach bleeding.

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Pregnancy

Caution

Please consult your doctor if you have any concerns regarding this; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor if you are breastfeeding; your doctor will decide whether Tizarest 100mg/2mg Tablet can be taken by breastfeeding mothers or not.

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Driving

Caution

Tizarest 100mg/2mg Tablet may cause dizziness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have liver problems or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney problems or any concerns regarding this.

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Children

Unsafe

Tizarest 100mg/2mg Tablet is not recommended for children as safety and effectiveness are not established.

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Heart

Unsafe

Tizarest 100mg/2mg Tablet is contraindicated in patients with heart conditions. Please seek medical advice before using this medicine.

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Geriatrics

Caution

Tizarest 100mg/2mg Tablet should be given to elderly patients only if prescribed by a doctor. If you have any concerns about using Tizarest 100mg/2mg Tablet in geriatrics, please consult your doctor.

What if I have taken an overdose of Tizarest 100mg/2mg Tablet

If you suspect an overdose, seek emergency medical attention immediately. Symptoms of an overdose may include extreme drowsiness, confusion, slow breathing, or severe dizziness.

Diet & Lifestyle Advise

  • Stay well hydrated: Stay well hydrated by drinking plenty of water throughout the day, which helps maintain proper muscle function.
  • Avoid strenuous activities: Avoid heavy lifting, sudden twisting movements, or strenuous exercise that could reinjure your healing muscles.
  • Use warm or cold therapy: Apply a warm compress or a cold pack to the painful area for 15 to 20 minutes at a time to soothe sore muscles naturally.
  • Avoid alcohol and limit caffeine: Avoid alcohol and limit caffeine, as both can worsen dehydration and increase the drowsiness caused by this medication.
  • Do gentle stretches: Incorporate gentle, doctor-approved stretches once your acute pain begins to subside to help prevent future muscle stiffness.
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Have a query?

How Soon It Starts Working

  • The time required for Tizarest 100mg/2mg Tablet to start to work: The effect of Tizarest 100mg/2mg Tablet is observed within 30 to 60 minutes of administration.
  • The time for which the effects of Tizarest 100mg/2mg Tablet last: Tizarest 100mg/2mg Tablet effect lasts for 8 to 12 hours.

What if you forget to take Tizarest 100mg/2mg Tablet

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Storage

• Store the tablets at room temperature, ideally between 15°C and 30°C (59°F to 86°F).

Drug Warnings

  • Avoid driving or operating machinery: Do not drive, operate heavy machinery, or perform tasks that require full mental alertness until you know how this medicine affects you, as it can cause significant drowsiness.
  • Stand up slowly: Stand up slowly from a sitting or lying position to prevent sudden drops in blood pressure, which can cause dizziness or fainting.
  • Watch for signs of liver problems: Check your skin and the whites of your eyes regularly for any yellowing, which could indicate liver stress.
  • Inform your healthcare providers: Inform any surgeon, dentist, or healthcare provider that you are taking Tizarest 100mg/2mg Tablet before undergoing any medical or dental procedures.
  • Do not share your medicine: Never share this medication with anyone else, even if they have similar symptoms of muscle pain or stiffness.
  • Do not stop suddenly: If you have been taking this medicine at high doses or for a long time, do not stop it suddenly without your doctor's advice. Stopping tizanidine abruptly may cause your muscle spasms to return and, in some people, lead to withdrawal effects such as high blood pressure and a fast heartbeat. Aceclofenac does not carry this withdrawal risk. 

verifiedApollotooltip
  • Blood thinners and pain relievers (like warfarin, aspirin, or ibuprofen): They may increase the risk of stomach ulcers or bleeding when taken with blood thinners (like warfarin) or other pain relievers (like aspirin or ibuprofen).
  • Blood pressure medicines, sleeping pills, or anxiety medicines: They can cause a severe drop in blood pressure or extreme sleepiness if taken with certain blood pressure medications, sleeping pills, or anxiety treatments.
  • CYP1A2 inhibitors (a group of medicines that affect how your body breaks down tizanidine): For example, ciprofloxacin or fluvoxamine can greatly increase the amount of tizanidine in your blood, raising the risk of severe drowsiness, dizziness, low blood pressure, and slow heart rate. Tell your doctor if you are taking these medicines, as they should not be taken together with tizanidine. 

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verifiedApollotooltip
  • Food: Food can affect how tizanidine is absorbed, and the effect may vary depending on the formulation. Take this medicine consistently, either always with food or always without food, as advised by your doctor, to help reduce the risk of side effects such as drowsiness, dizziness, or low blood pressure. 

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Habit Forming

No

Therapeutic Class

[ANALGESICS]

FAQs

Tizarest 100mg/2mg Tablet is used to treat pain and inflammation associated with musculoskeletal and joint disorders.
Tizarest 100mg/2mg Tablet contains Tizanidine and Aceclofenac. Tizanidine works on the centres of the spinal cord and brain. This helps relieve muscle stiffness and improve muscle movements. Aceclofenac works by blocking the effect of prostaglandins, thereby reducing mild to moderate pain and inflammation.
Tizarest 100mg/2mg Tablet is used to reduce and relieve pain and inflammation associated with osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. Arthritis is the tenderness and swelling in the joints.
Diarrhoea may be a side effect of Tizarest 100mg/2mg Tablet. Drink enough fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.
Taking Tizarest 100mg/2mg Tablet can elevate symptoms of gastric ulcer and bleeding. So, talk to your doctor before taking Tizarest 100mg/2mg Tablet if you have gastrointestinal bleeding or other bleeding problems like haemophilia before using Tizarest 100mg/2mg Tablet.
Tizarest 100mg/2mg Tablet and Hifenac-MR are similar, as they relieve pain and inflammation but differ in their active components.
Yes, Tizarest 100mg/2mg Tablet is a painkiller. However, it is not intended for all types of pain. Use it as prescribed to avoid side effects.
Tizarest 100mg/2mg Tablet contains Aceclofenac and Tizanidine, making it effective for pain relief and muscle relaxation. Zerodol-SP, on the other hand, includes Aceclofenac, Paracetamol, and Serratiopeptidase, which help reduce pain, inflammation, and swelling. Both should be used as directed by a doctor.
Diabetic patients can use Tizarest 100mg/2mg Tablet, but it should be taken with caution as it may impact blood sugar levels. Therefore, please consult a doctor before using Tizarest 100mg/2mg Tablet to ensure its safety for your condition. Regular monitoring of blood sugar is recommended.
You are recommended to consult a doctor before taking Tizarest 100mg/2mg Tablet with paracetamol or other medicines to avoid potential interactions.
Yes, the use of Tizarest 100mg/2mg Tablet can cause nausea and vomiting. Take it with food or milk, or with antacids, to prevent nausea. Avoid consuming fried or fatty foods with Tizarest 100mg/2mg Tablet. If vomiting occurs, drink plenty of water or other fluids by taking small, frequent sips. If vomiting persists, consult your doctor.
Tizarest 100mg/2mg Tablet usually starts working within 20-30 minutes of taking it, though the onset may vary depending on individual health conditions.
Tizarest 100mg/2mg Tablet contains aceclofenac and tizanidine as its active components.
Do not take higher than the recommended dose of Tizarest 100mg/2mg Tablet as it can lead to increased side effects. Therefore, do not exceed the recommended dose. If your symptoms worsen, please consult your doctor.
Store Tizarest 100mg/2mg Tablet at room temperature in a cool and dry place as advised on the label. Protect from light and moisture. Keep it out of reach of children.
Tizarest 100mg/2mg Tablet is safe when used as per the dose and duration advised by a doctor.
Tizarest 100mg/2mg Tablet is contraindicated in individuals with known allergies to its ingredients, or patients with high blood pressure, heart problems, stomach ulcers, bleeding disorders, inflammatory bowel disease, high cholesterol, diabetes, asthma, or liver and kidney issues. Tizarest 100mg/2mg Tablet is not recommended for children, and you should consult your doctor if you are pregnant or breastfeeding.
You are recommended not to stop taking Tizarest 100mg/2mg Tablet without consulting your doctor as stopping it suddenly can cause adverse effects. Therefore, continue taking Tizarest 100mg/2mg Tablet for the duration prescribed and if you experience any difficulty while taking Tizarest 100mg/2mg Tablet, consult your doctor so that the dose may be reduced gradually.
Take Tizarest 100mg/2mg Tablet as directed by your doctor. Swallow Tizarest 100mg/2mg Tablet whole with a glass of water; do not crush, chew, or break it.
If you miss a dose of Tizarest 100mg/2mg Tablet, take it as soon as you remember and if it is the time for the next dose, skip the missed dose and continue with the regular dose. Avoid taking double dose to make up for the missed one.
Tizarest 100mg/2mg Tablet may cause side effects such as nausea, vomiting, stomach pain, diarrhoea, loss of appetite, and heartburn. These do not require any medical treatment as they will gradually reduce over time. Consult a doctor if these side effects persist for longer durations.
It is highly recommended to take Tizarest 100mg/2mg Tablet with food or a glass of milk. Taking it on an empty stomach increases the risk of indigestion and stomach upset. Talk to your doctor or pharmacist if you experience persistent stomach discomfort.
Yes, drowsiness and dizziness are common side effects of this medication due to its muscle-relaxing properties. Avoid driving or operating machinery until you know how this medicine affects you. Talk to your doctor if the sleepiness is severe.
No, you must avoid drinking alcohol while taking this medicine. Alcohol can dangerously increase drowsiness, cause a severe drop in blood pressure, and increase the risk of liver damage. Talk to your doctor if you have concerns about alcohol use.
This medication is generally not recommended during pregnancy or breastfeeding unless specifically deemed necessary by your doctor. It may pose risks to the developing baby. Talk to your doctor to discuss safer alternatives.
You should avoid taking other pain relievers alongside Tizarest 100mg/2mg Tablet, as this significantly increases the risk of stomach irritation and bleeding. Talk to your doctor or pharmacist before combining any pain medications.
Older adults may be more sensitive to the side effects of this medication, particularly dizziness, drowsiness, and stomach issues, which can increase the risk of falls. Talk to your doctor to determine if this is the safest option for you.
Dry mouth is a common side effect of the muscle relaxant component in this medicine. You can manage this by sucking on sugar-free candies, chewing sugar-free gum, or taking frequent sips of water. Talk to your doctor or pharmacist if this symptom becomes severe or bothersome.

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Country of origin

India
Other Info - TI69527
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