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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Tobamist Respules 5X5 ml is an aminoglycoside antibiotic used to treat chest infections caused by the bacteria Pseudomonas aeruginosa in cystic fibrosis. It helps by inhibiting the protein synthesis of the bacterial cell and therby helps fight infection in the lungs. Sometimes, you may experience certain common side effects, such as discolouration of the substance you cough up (sputum), worsening of lung function test results, runny or stuffy nose, sneezing, hoarseness,feeling unwell, muscle pain, etc
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Whats That

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Composition :

TOBRAMYCIN-300MG

Manufacturer/Marketer :

Cipla Ltd

Consume Type :

INHALATION

Return Policy :

Not Returnable

Expires on or after :

About Tobamist Respules 5X5 ml

Tobamist Respules 5X5 ml belongs to the class of aminoglycoside antibiotics. Tobamist Respules 5X5 ml is used to treat chest infections caused by the bacteria Pseudomonas aeruginosa in cystic fibrosis patients aged six years and older. Pseudomonas aeruginosa is a type of bacteria that can cause lung or chest infections, especially in people who already have a lung disease (cystic fibrosis) or an issue with their immune system.

Tobamist Respules 5X5 ml contains Tobramycin, an aminoglycoside antibiotic that fights the infection in your lungs by interfering with protein synthesis in Pseudomonas bacterial cell and helps you breathe better.

Use the Tobamist Respules 5X5 ml as prescribed by your doctor. Sometimes, you may experience certain common side effects, such as runny or stuffy nose, sneezing, voice alteration (hoarseness), discolouration of the substance you cough up (sputum), worsening of lung function test results, feeling unwell, muscle pain and voice alteration with sore throat and difficulty swallowing (laryngitis). Most of these side effects do not require medical attention and resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Do not use Tobamist Respules 5X5 ml if you are allergic to any of its components or other aminoglycoside antibiotics. Do not use the Tobamist Respules 5X5 ml without consulting your doctor if you are pregnant or breastfeeding. Tell your doctor before prescribing Tobamist Respules 5X5 ml if you have hearing problems, kidney problems, unusual difficulty breathing with wheezing or coughing, chest tightness, blood in the sputum, muscle weakness, and Parkinson's disease. Tobamist Respules 5X5 ml is not recommended to be used in children under the age of six.

Uses of Tobamist Respules 5X5 ml

Treatment of Chest infections (Pseudomonas aeruginosa infection)

Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication to ensure safe and effective use.• Check the label for directions before using it. Twist off the top of the respule (a small plastic container containing a solution) and pour the solution into the nebuliser chamber. This solution is made into a fine mist to breathe in. Inhale the medicine slowly and deeply through the nebuliser's mouthpiece.• Clean the nebulizer pieces (cup, mouthpiece, mask, and tubing) after each use.

Medicinal Benefits

Tobamist Respules 5X5 ml contains Tobramycin, an aminoglycoside antibiotic that fights pulmonary infection by interfering with protein synthesis in Pseudomonas bacterial cells and allows you to breathe easier.

How Tobamist Respules 5X5 ml Works

Tobamist Respules 5X5 ml contains Tobramycin, an aminoglycoside antibiotic that fights the infection in your lungs by interfering with protein synthesis in Pseudomonas bacterial cell and helps you breathe better.

Storage

• Store in a cool and dry place away from sunlight.
• Keep out of sight and reach of children.
• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Tobamist Respules 5X5 ml
Here are the steps to manage the medication-triggered Cough:
  • Tell your doctor about the cough symptoms you're experiencing, which may be triggered by your medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your cough symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids, such as water, tea, or soup, to help thin out mucus and soothe your throat.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your cough persists or worsens, consult your doctor for further guidance.
  • Drink warm fluids such as warm water with honey, broth, soup or herbal tea to soothe sore throat.
  • Gargle with warm salt water.
  • Suck on lozenges to increase the production of saliva and soothe your throat.
  • Use a humidifier to soothe sore throat as it adds moisture to the air and makes breathing easier.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Avoid smoking and intake of any tobacco products as it worsens lung disorders.
  • Get a physical examination, follow your doctor's instructions, and get required vaccinations.
  • Be physically active and eat healthy food.
  • Prefer practising yoga and meditation to reduce stress and anxiety.
  • Practice good hygiene and stay away from places where air pollution is high.

What if I have taken an overdose of Tobamist Respules 5X5 ml

Overdose of Tobamist Respules 5X5 ml may cause black, tarry stools, chest pain or tightness, continuing ringing or buzzing or other unexplained noise in the ears, feeling of fullness in the ears. If an overdose is suspected, seek immediate medical help.

Drug Warnings

Do not use Tobamist Respules 5X5 ml if you are allergic to any of the components or other aminoglycoside antibiotics (neomycin, paromomycin, kanamycin). Do not use the Tobamist Respules 5X5 ml without consulting your doctor if you are pregnant or breastfeeding. Tell your doctor before prescribing Tobamist Respules 5X5 ml if you have hearing problems, kidney problems, unusual difficulty breathing with wheezing or coughing, chest tightness, blood in the sputum, muscle weakness, and Parkinson's disease. Children and adolescents aged six and up are eligible to use Tobamist Respules 5X5 ml. Tobamist Respules 5X5 ml should not be given to children under the age of six. Before taking the Tobamist Respules 5X5 ml, notify your doctor about your medical history and other medications you are now taking to rule out any potential adverse effects or interactions.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Tobamist Respules 5X5 ml:
Coadministration of cidofovir with Tobamist Respules 5X5 ml can cause kidney problems.

How to manage the interaction:
Taking Tobamist Respules 5X5 ml with Cidofovir is not recommended, but can be taken if prescribed by a doctor. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm contact your doctor immediately. Do not stop using any medications without consulting a doctor.
How does the drug interact with Tobamist Respules 5X5 ml:
Taking Tobamist Respules 5X5 ml with Polymyxin B can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between Tobamist Respules 5X5 ml and Polymyxin b, you can take these medicines together if prescribed by a doctor. However, if you experience hearing loss, ringing in the ears, difficulty breathing, nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Tobamist Respules 5X5 ml:
Takin human immunoglobulin with Tobamist Respules 5X5 ml may raise the risk of kidney problems.

How to manage the interaction:
Although taking Human immunoglobulin and Tobamist Respules 5X5 ml together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
TobramycinDoxacurium chloride
Severe
How does the drug interact with Tobamist Respules 5X5 ml:
Taking Tobamist Respules 5X5 ml with doxacurium chloride can increase the risk of respiratory depression(hypoventilation).

How to manage the interaction:
Although there is a possible interaction between Tobamist Respules 5X5 ml and Doxacurium chloride, you can take these medicines together if prescribed by your doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Tobamist Respules 5X5 ml:
Taking Tobamist Respules 5X5 ml with succinylcholine can increase the risk of respiratory depression(hypoventilation).

How to manage the interaction:
There may be a possibility of interaction between Suxamethonium and Tobamist Respules 5X5 ml, but it can be taken if prescribed by a doctor. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Tobamist Respules 5X5 ml:
Coadministration of Tobamist Respules 5X5 ml with Colistin can increase the blood levels and risk of Colistin side effects.

How to manage the interaction:
Although there is a possible interaction between Colistin and Tobamist Respules 5X5 ml, you can take these medicines together if prescribed by your doctor. However, if you experience, shortness of breath, muscle pain, dizziness, or palpitations, contact your doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Tobamist Respules 5X5 ml:
Using Atracurium with Tobamist Respules 5X5 ml can increase the risk of respiratory depression (breathing disorder).

How to manage the interaction:
Although there is a interaction between Tobamist Respules 5X5 ml and Atracurium, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to your doctor.
TobramycinCisatracurium
Severe
How does the drug interact with Tobamist Respules 5X5 ml:
Combining Tobamist Respules 5X5 ml together with cisatracurium can increase the neuromuscular blocking effects( disorder that effects nerves and muscles) of cisatracurium.

How to manage the interaction:
Although there is a possible interaction between Cisatracurium and Tobamist Respules 5X5 ml, you can take these medicines together if prescribed by your doctor. If you have any of these symptoms - having trouble breathing contact your doctor right away. Do not stop using any medications without a doctor's advice.
TobramycinMannitol
Severe
How does the drug interact with Tobamist Respules 5X5 ml:
Taking mannitol with Tobamist Respules 5X5 ml can increase the risk of hearing loss and kidney problems.

How to manage the interaction:
Although taking Tobamist Respules 5X5 ml and Mannitol together can evidently cause an interaction, it can be taken if your doctor has suggested it. Do not stop using any medications without talking to your doctor.
How does the drug interact with Tobamist Respules 5X5 ml:
Using Tobamist Respules 5X5 ml together with everolimus can increase the risk of kidney problems.

How to manage the interaction:
Although there is a possible interaction between Everolimus and Tobamist Respules 5X5 ml, you can take these medicines together if prescribed by a doctor. However, if you experience sudden weight gain, feeling out of breath, or having kidney problems. If you experience nausea, vomiting, loss of appetite, weight loss, swelling, muscle cramps, weakness, dizziness, confusion, or an irregular heartbeat contact a doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • It would be best to take probiotics after taking the full course of Tobamist Respules 5X5 ml to restore some healthy bacteria in the intestine that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut and kimchi can help restore the intestine's good bacteria.
  • Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria which helps stimulate their growth. Thus fibre foods may help restore healthy gut bacteria after taking a course of antibiotics. Whole grains, like whole-grain bread, and brown rice, should be included in your diet.
  • Avoid taking too many calcium-enriched foods and drinks as it might affect the working of Tobamist Respules 5X5 ml.
  • Avoid intake of alcoholic beverages with Tobamist Respules 5X5 ml as it can make you dehydrated and affect your sleep. This can make it harder for your body to aid the Tobamist Respules 5X5 ml in fighting off infections.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS
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Alcohol

Caution

It is unknown if alcohol affects Tobamist Respules 5X5 ml. However, it is advisable to limit or avoid alcohol as a precautionary measure.

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Pregnancy

Caution

Tobamist Respules 5X5 ml may not be recommended to be used in pregnancy. If you are pregnant, please consult your doctor. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor as there is no substantial research yet on using Tobamist Respules 5X5 ml in breastfeeding/nursing mothers.

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Driving

Safe if prescribed

Tobamist Respules 5X5 ml may not affect your ability to drive, use, or operate machines.

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Liver

Caution

Limited information about the usage of Tobamist Respules 5X5 ml in patients with liver disease is available. Please consult your physician. Your doctor will weigh the benefits and potential risks before prescribing Tobamist Respules 5X5 ml.

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Kidney

Caution

Limited information about the usage of Tobamist Respules 5X5 ml in patients with kidney disease is available. Please consult your physician. Your doctor will weigh the benefits and potential risks before prescribing Tobamist Respules 5X5 ml.

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Children

Caution

Children and adolescents aged six and up are eligible to use Tobamist Respules 5X5 ml. Tobamist Respules 5X5 ml should not be given to children under the age of six.

Have a query?

FAQs

Tobamist Respules 5X5 ml belongs to the class of aminoglycoside antibiotics. Tobamist Respules 5X5 ml is used to treat chest infections caused by the bacteria Pseudomonas aeruginosa in cystic fibrosis patients aged six years and older.

Tobamist Respules 5X5 ml contains Tobramycin, an aminoglycoside antibiotic that fights pulmonary infection by interfering with protein synthesis in Pseudomonas bacterial cells and allows you to breathe easier.

Please do not stop using Tobamist Respules 5X5 ml until the course prescribed by your doctor has been completed. If you stop taking Tobamist Respules 5X5 ml too soon, your symptoms may recur.

Voice alteration (hoarseness) is the most common side effect of Tobamist Respules 5X5 ml. If you experience any major changes, immediately consult your doctor.

Tobamist Respules 5X5 ml is recommended not to use it for more than the prescribed duration. Please reach out to your doctor if your symptoms do not improve or if it becomes worse.

Tobamist Respules 5X5 ml is only used to treat chest infections caused by the bacteria Pseudomonas aeruginosa in cystic fibrosis patients.

Country of origin

India

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Other Info - TOB0011

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