Tobramix 300 mg Inhalation Solution 5 ml

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Written By Bayyarapu Mahesh Kumar , M Pharmacy

Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Tobramix 300 mg Inhalation Solution 5 ml is an aminoglycoside antibiotic used to treat chest infections caused by the bacteria Pseudomonas aeruginosa in cystic fibrosis. It helps by inhibiting the protein synthesis of the bacterial cell and therby helps fight infection in the lungs. Sometimes, you may experience certain common side effects, such as discolouration of the substance you cough up (sputum), worsening of lung function test results, runny or stuffy nose, sneezing, hoarseness,feeling unwell, muscle pain, etc

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About Tobramix 300 mg Inhalation Solution 5 ml

Tobramix 300 mg Inhalation Solution 5 ml belongs to the class of aminoglycoside antibiotics. Tobramix 300 mg Inhalation Solution 5 ml is used to treat chest infections caused by the bacteria Pseudomonas aeruginosa in cystic fibrosis patients aged six years and older. Pseudomonas aeruginosa is a type of bacteria that can cause lung or chest infections, especially in people who already have a lung disease (cystic fibrosis) or an issue with their immune system.

Tobramix 300 mg Inhalation Solution 5 ml contains Tobramycin, an aminoglycoside antibiotic that fights the infection in your lungs by interfering with protein synthesis in Pseudomonas bacterial cell and helps you breathe better.

Use the Tobramix 300 mg Inhalation Solution 5 ml as prescribed by your doctor. Sometimes, you may experience certain common side effects, such as runny or stuffy nose, sneezing, voice alteration (hoarseness), discolouration of the substance you cough up (sputum), worsening of lung function test results, feeling unwell, muscle pain and voice alteration with sore throat and difficulty swallowing (laryngitis). Most of these side effects do not require medical attention and resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Do not use Tobramix 300 mg Inhalation Solution 5 ml if you are allergic to any of its components or other aminoglycoside antibiotics. Do not use the Tobramix 300 mg Inhalation Solution 5 ml without consulting your doctor if you are pregnant or breastfeeding. Tell your doctor before prescribing Tobramix 300 mg Inhalation Solution 5 ml if you have hearing problems, kidney problems, unusual difficulty breathing with wheezing or coughing, chest tightness, blood in the sputum, muscle weakness, and Parkinson's disease. Tobramix 300 mg Inhalation Solution 5 ml is not recommended to be used in children under the age of six.

Uses of Tobramix 300 mg Inhalation Solution 5 ml

Treatment of Chest infections (Pseudomonas aeruginosa infection)

Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication to ensure safe and effective use.• Check the label for directions before using it. Twist off the top of the respule (a small plastic container containing a solution) and pour the solution into the nebuliser chamber. This solution is made into a fine mist to breathe in. Inhale the medicine slowly and deeply through the nebuliser's mouthpiece.• Clean the nebulizer pieces (cup, mouthpiece, mask, and tubing) after each use.

Medicinal Benefits

Tobramix 300 mg Inhalation Solution 5 ml contains Tobramycin, an aminoglycoside antibiotic that fights pulmonary infection by interfering with protein synthesis in Pseudomonas bacterial cells and allows you to breathe easier.

How Tobramix 300 mg Inhalation Solution 5 ml Works

Tobramix 300 mg Inhalation Solution 5 ml contains Tobramycin, an aminoglycoside antibiotic that fights the infection in your lungs by interfering with protein synthesis in Pseudomonas bacterial cell and helps you breathe better.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Tobramix 300 mg Inhalation Solution 5 ml

Overdose of Tobramix 300 mg Inhalation Solution 5 ml may cause black, tarry stools, chest pain or tightness, continuing ringing or buzzing or other unexplained noise in the ears, feeling of fullness in the ears. If an overdose is suspected, seek immediate medical help.

Drug Warnings

Do not use Tobramix 300 mg Inhalation Solution 5 ml if you are allergic to any of the components or other aminoglycoside antibiotics (neomycin, paromomycin, kanamycin). Do not use the Tobramix 300 mg Inhalation Solution 5 ml without consulting your doctor if you are pregnant or breastfeeding. Tell your doctor before prescribing Tobramix 300 mg Inhalation Solution 5 ml if you have hearing problems, kidney problems, unusual difficulty breathing with wheezing or coughing, chest tightness, blood in the sputum, muscle weakness, and Parkinson's disease. Children and adolescents aged six and up are eligible to use Tobramix 300 mg Inhalation Solution 5 ml. Tobramix 300 mg Inhalation Solution 5 ml should not be given to children under the age of six. Before taking the Tobramix 300 mg Inhalation Solution 5 ml, notify your doctor about your medical history and other medications you are now taking to rule out any potential adverse effects or interactions.

Diet & Lifestyle Advise

It would be best to take probiotics after taking the full course of Tobramix 300 mg Inhalation Solution 5 ml to restore some healthy bacteria in the intestine that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut and kimchi can help restore the intestine's good bacteria.
Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria which helps stimulate their growth. Thus fibre foods may help restore healthy gut bacteria after taking a course of antibiotics. Whole grains, like whole-grain bread, and brown rice, should be included in your diet.
Avoid taking too many calcium-enriched foods and drinks as it might affect the working of Tobramix 300 mg Inhalation Solution 5 ml.
Avoid intake of alcoholic beverages with Tobramix 300 mg Inhalation Solution 5 ml as it can make you dehydrated and affect your sleep. This can make it harder for your body to aid the Tobramix 300 mg Inhalation Solution 5 ml in fighting off infections.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS

Alcohol

Caution

It is unknown if alcohol affects Tobramix 300 mg Inhalation Solution 5 ml. However, it is advisable to limit or avoid alcohol as a precautionary measure.

Pregnancy

Caution

Tobramix 300 mg Inhalation Solution 5 ml may not be recommended to be used in pregnancy. If you are pregnant, please consult your doctor. Your doctor will prescribe only if the benefits outweigh the risks.

Breast Feeding

Caution

Consult your doctor as there is no substantial research yet on using Tobramix 300 mg Inhalation Solution 5 ml in breastfeeding/nursing mothers.

Driving

Safe if prescribed

Tobramix 300 mg Inhalation Solution 5 ml may not affect your ability to drive, use, or operate machines.

Liver

Caution

Limited information about the usage of Tobramix 300 mg Inhalation Solution 5 ml in patients with liver disease is available. Please consult your physician. Your doctor will weigh the benefits and potential risks before prescribing Tobramix 300 mg Inhalation Solution 5 ml.

Kidney

Caution

Limited information about the usage of Tobramix 300 mg Inhalation Solution 5 ml in patients with kidney disease is available. Please consult your physician. Your doctor will weigh the benefits and potential risks before prescribing Tobramix 300 mg Inhalation Solution 5 ml.

Children

Caution

Children and adolescents aged six and up are eligible to use Tobramix 300 mg Inhalation Solution 5 ml. Tobramix 300 mg Inhalation Solution 5 ml should not be given to children under the age of six.

Have a query?

FAQs

What is the use of Tobramix 300 mg Inhalation Solution 5 ml?

Tobramix 300 mg Inhalation Solution 5 ml belongs to the class of aminoglycoside antibiotics. Tobramix 300 mg Inhalation Solution 5 ml is used to treat chest infections caused by the bacteria Pseudomonas aeruginosa in cystic fibrosis patients aged six years and older.

How does Tobramix 300 mg Inhalation Solution 5 ml work?

Tobramix 300 mg Inhalation Solution 5 ml contains Tobramycin, an aminoglycoside antibiotic that fights pulmonary infection by interfering with protein synthesis in Pseudomonas bacterial cells and allows you to breathe easier.

Can I stop using the Tobramix 300 mg Inhalation Solution 5 ml once my symptoms have subsided?

Please do not stop using Tobramix 300 mg Inhalation Solution 5 ml until the course prescribed by your doctor has been completed. If you stop taking Tobramix 300 mg Inhalation Solution 5 ml too soon, your symptoms may recur.

Does Tobramix 300 mg Inhalation Solution 5 ml cause voice alteration (hoarseness)?

Voice alteration (hoarseness) is the most common side effect of Tobramix 300 mg Inhalation Solution 5 ml. If you experience any major changes, immediately consult your doctor.

Can I use Tobramix 300 mg Inhalation Solution 5 ml for prolonged durations?

Tobramix 300 mg Inhalation Solution 5 ml is recommended not to use it for more than the prescribed duration. Please reach out to your doctor if your symptoms do not improve or if it becomes worse.

Does Tobramix 300 mg Inhalation Solution 5 ml ideal to use in all types of chest infections?

Tobramix 300 mg Inhalation Solution 5 ml is only used to treat chest infections caused by the bacteria Pseudomonas aeruginosa in cystic fibrosis patients.

Country of origin

India

Manufacturer/Marketer address

E-11, Moti Nagar , New Delhi-110015

Other Info - TOB0113

Author Details

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 9:23 AM IST

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FAQs

What is the use of Tobramix 300 mg Inhalation Solution 5 ml?

How does Tobramix 300 mg Inhalation Solution 5 ml work?

Can I stop using the Tobramix 300 mg Inhalation Solution 5 ml once my symptoms have subsided?

Does Tobramix 300 mg Inhalation Solution 5 ml cause voice alteration (hoarseness)?

Can I use Tobramix 300 mg Inhalation Solution 5 ml for prolonged durations?

Does Tobramix 300 mg Inhalation Solution 5 ml ideal to use in all types of chest infections?

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