Tofadoz Tablet 10's
MRP ₹460.5
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₹69.1 Cashback (15%)
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About Tofadoz Tablet
Tofadoz Tablet is used to treat rheumatoid arthritis (an autoimmune disease which leads to joint pain and damage), psoriatic arthritis (an inflammatory condition of the joints), and ulcerative colitis (an inflammatory disease of the large intestine).
Tofadoz Tablet contains Tofacitinib, which works by blocking the Janus kinase enzyme, thereby lowering inflammation and symptoms associated with rheumatoid and psoriatic arthritis.
Not everyone who is taking Tofadoz Tablet will get these side effects. In some cases, you may experience common side effects such as diarrhoea, headache, upper respiratory tract infection, cold, nausea, and vomiting. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
You can take Tofadoz Tablet with or without food. It should be swallowed as a whole with a glass of water. Do not chew, bite, crush, or break it. Your doctor will advise you on how often you should take your tablets based on your medical condition. It is always important to complete your treatment course for better results.
Avoid taking Tofadoz Tablet if you are allergic to it. Inform your doctor if you have an active infection, if you are taking immunosuppressants, medicines that affect the immune system or corticosteroids. Avoid taking Tofadoz Tablet if you are pregnant or breastfeeding. Tofadoz Tablet is not recommended for use in children below 18 years as safety and effectiveness have not been established.
Uses of Tofadoz Tablet
Tofadoz Tablet is used in the treatment of Rheumatoid arthritis, Psoriatic arthritis, and Ulcerative colitis. The detailed uses of Tofadoz Tablet are as follows:
- Treatment of Rheumatoid Arthritis: Tofadoz Tablet helps to manage moderate to severe rheumatoid arthritis by reducing joint pain, inflammation, and slowing disease progression.
- Management of Psoriatic Arthritis: Tofadoz Tablet treats active psoriatic arthritis by reducing joint pain, swelling, stiffness, and improving overall joint function.
- Treatment of Ulcerative Colitis: Tofadoz Tablet helps to induce and maintain remission in moderate to severe ulcerative colitis.
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Directions for Use
- Tofadoz Tablet can be taken with or without food.
- It is recommended to take Tofadoz Tablet 1-2 times a day, depending on your medical condition, or as prescribed by your doctor.
- Swallow Tofadoz Tablet as a whole with a glass of water.
- Do not crush, chew, or break it.
Medicinal Benefits
- Tofadoz Tablet belongs to a group of medicines called Janus kinase inhibitors used to treat rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis.
- Tofadoz Tablet is indicated for patients with moderate to severe rheumatic arthritis, and psoriatic arthritis who have had intolerance or inadequate response to methotrexate or DMARDs (Disease-Modifying Anti-Rheumatic Drugs).
- This medicine helps lower inflammation and symptoms associated with rheumatoid and psoriatic arthritis.
How Tofadoz Tablet Works
Storage
- Practice good hygiene by washing hands frequently when touching any wounds.
- Apply creams or lotions to the dry skin and moisturize it.
- Wear the proper clothing and footwear when working outside.
- Cover the wounds with bandage and change it daily.
- Avoid baths at swimming pools, lakes and rivers.
- Drink a lot of water to control diarrhoea and prevent dehydration.
- Avoid spicy, fatty, or high-fiber foods that may irritate the colon.
- Reduce stress through methods such as deep breathing or meditation.
- Include probiotics or supplements containing live bacteria to maintain the health of the gut.
- Quit smoking since smoking makes colitis symptoms worse.
- See your doctor right away if you experience extreme inflammation, bleeding stools, or abdominal pain.
- To promote overall health, drink plenty of water and consume hydrating foods like watermelon and leafy greens.
- Support gut health with probiotic-rich foods such as yoghurt and sauerkraut.
- Eat antioxidant-rich foods like berries and green tea, while limiting sugary drinks, alcohol, and processed foods.
- Additionally, reduce stress through relaxation techniques like deep breathing and meditation.
- Inform your doctor about the medication you're taking and the UTI symptoms you're experiencing.
- Your doctor may adjust your medication regimen or consider alternative medications or dosages that may reduce the risk of UTIs.
- Drink plenty of water (at least 8-10 glasses a day) to help flush out bacteria. Avoid sugary drinks and caffeine, which can exacerbate UTI symptoms.
- Urinate when you feel the need rather than holding it in. This can help prevent bacterial growth and reduce the risk of UTIs.
- Consider cranberry supplements: Cranberry supplements may help prevent UTIs by preventing bacterial adhesion.
- Monitor UTI symptoms and report any changes to your doctor.
- If antibiotics are prescribed, take them as directed and complete the full course.
What if I have taken an overdose of Tofadoz Tablet
Drug Warnings
- Do not take Tofadoz Tablet if you are allergic to any of its components; if you have a severe infection, bloodstream infection, or if you have severe liver problems such as cirrhosis.
- Inform your doctor if you have an infection, symptoms of infection, a condition that increases chances of infection, are taking any medicines that affect the immune system; have or had a history of tuberculosis, chronic lung disease, liver problems, hepatitis B/C, cancer, inflammation/ulcers of the large intestine, or kidney problems; are planning to get vaccinated; or have heart problems, high cholesterol, high blood pressure, heart attack, diabetes, or blood clotting problems.
- If your white blood cell count or red blood cell count is low, avoid taking Tofadoz Tablet .
- Inform your doctor if you notice painful blisters on the skin or if you experience breathing difficulties. Inform your doctor about your complete medical and medication history before starting treatment with Tofadoz Tablet , which helps the physician decide the best treatment plan.
Drug-Drug Interactions
Drug-Drug Interactions
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When Tofadoz Tablet and Clozapine are taken together, that may increase the risk of severe infections.
How to manage the interaction:
There may be a possibility of interaction between Tofadoz Tablet and Clozapine, but it can be taken if prescribed by a doctor. Your doctor can recommend other options that won't cause problems when taken together. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without first talking to your doctor.
Taking Tofadoz Tablet with Oxaliplatin may increase the risk of infection.
How to manage the interaction:
Although taking Oxaliplatin and Tofadoz Tablet together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without talking to your doctor.
When used with linezolid, Tofadoz Tablet may raise the risk of serious infections.
How to manage the interaction:
Although taking linezolid and Tofadoz Tablet together can result in an interaction, they can be taken if a doctor has prescribed it. However, if you develop a fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in sputum, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, contact a doctor immediately. Do not discontinue any medication without consulting a doctor.
When Tofadoz Tablet is taken with Nelfinavir, that may increase the risk of side effects.
How to manage the interaction:
Although taking Tofadoz Tablet and Nelfinavir together can evidently cause an interaction, it can be taken if your doctor has suggested it. Do not stop using any medications without a doctor's advice.
Using Tofadoz Tablet together with adalimumab can increase the risk of serious infections
How to manage the interaction:
Although taking Tofadoz Tablet and Adalimumab together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, consult your doctor if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without consulting your doctor.
Taking Tofadoz Tablet and bortezomib may increase the risk of infections.
How to manage the interaction:
Although using Bortezomib and Tofadoz Tablet together can possibly result in an interaction, they can be taken together if advised by your doctor. However, contact a doctor if you experience fever, chills, diarrhea, sore throat, muscle aches, red or irritated skin, or burning during urination. Do not stop taking any medications without consulting a doctor.
Coadministration of Tofadoz Tablet and Gemcitabine can lead to or increase the risk of infection.
How to manage the interaction:
There may be a possibility of interaction between Tofadoz Tablet and Gemcitabine, but it can be taken if advised by a doctor. Contact your doctor immediately if you develop symptoms like fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without consulting a doctor.
Coadministration of Ketoconazole and Tofadoz Tablet may increase the blood levels and effects of Tofadoz Tablet which may lead to side effects (low blood cell counts, anemia, serious infections, and elevated blood lipid levels).
How to manage the interaction:
Although taking Ketoconazole and Tofadoz Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience symptoms like paleness, exhaustion, dizziness, fainting, fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in the phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning when urinating, consult a doctor. Do not stop using any medications without a doctor's advice.
Taking Tofadoz Tablet and Everolimus may increase the risk of serious infection.
How to manage the interaction:
Co-administration of Tofadoz Tablet with Everolimus can result in an interaction, but it can be taken if a doctor has advised it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without talking to a doctor.
Taking Rituximab and Tofadoz Tablet may increase the risk infections.
How to manage the interaction:
Taking Tofadoz Tablet with Rituximab together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you experience symptoms such as fever, chills, loose stools, sore throat, muscle aches, shortness of breath, blood in phlegm, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without consulting a doctor.
Drug-Food Interactions
Drug-Food Interactions
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Grapefruit, Grapefruit Juice
How to manage the interaction:
Consuming grapefruit products while taking Tofadoz Tablet can increase the risk of side effects. Avoid consuming grapefruit products while being treated with Tofadoz Tablet, as it can lead to an interaction.
Diet & Lifestyle Advise
- Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.
- Performing yoga may also help in improving joint flexibility and pain management.
- Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
- Get adequate sleep, as resting the muscles can help in reducing inflammation and swelling.
- De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
- Acupuncture, massage and physical therapy may also be helpful.
- Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
- Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
- Avoid smoking and alcohol consumption.
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Alcohol
Caution
It is not known if alcohol interacts with Tofadoz Tablet , so please consult a doctor.
Pregnancy
Unsafe
Tofadoz Tablet must not be taken during pregnancy. If you are a woman of child-bearing potential, use effective contraception during the treatment with Tofadoz Tablet and for 4 weeks after discontinuation.
Breast Feeding
Unsafe
Avoid breastfeeding while taking Tofadoz Tablet . Please consult a doctor if you have any concerns.
Driving
Safe
Tofadoz Tablet generally does not affect your ability to drive. However, drive or operate machinery only if you are alert.
Liver
Caution
Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this. Tofadoz Tablet is not recommended for patients with severe liver problems.
Kidney
Caution
Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.
Children
Unsafe
Tofadoz Tablet is not recommended for children below 18 years as safety and effectiveness were not established.
Heart
No serious side effects were observed. But it requires careful consideration and monitoring due to increased risks of heart-related problems, particularly in patients with existing cardiovascular risk factors.
Geriatrics
Caution
No serious adverse effects were observed; however, it requires careful consideration and caution due to the increased risk of certain adverse events, particularly infections.
FAQs
Tofadoz Tablet is used to treat rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis.
Tofadoz Tablet works by blocking Janus kinase enzyme, thereby lowers inflammation and symptoms associated with rheumatoid and psoriatic arthritis.
Hypertension/high blood pressure could be a side-effect of Tofadoz Tablet . Consult your doctor before taking Tofadoz Tablet if you have high blood pressure or if you are taking anti-hypertensive medicines.
Diarrhoea might be a side-effect of Tofadoz Tablet . Eat non-spicy meals and drink plenty of fluids to prevent dehydration if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.
Tofadoz Tablet might impair fertility in females of reproductive potential. It is not known if the effect is reversible. Therefore, talk to a doctor before starting Tofadoz Tablet if you are trying to become pregnant or if you have any concerns regarding this.
Tofadoz Tablet affects the immune system and might lower the ability of the immune system to fight infections. Inform your doctor if you have an active infection, if you have a condition that increases the chance of having infections, if you are taking immunosuppressants, medicines that affect the immune system or corticosteroids.
Tofadoz Tablet is not recommended for patients with severe liver impairment. Dose adjustment may be needed in patients with mild to moderate liver impairment. Please consult the doctor if you have liver problems.
Tofadoz Tablet may increase the risk of cancer by changing the way the immune system works. Inform the doctor if you ever had any type of cancer.
Tofadoz Tablet may begin working within 2-8 weeks after starting the treatment.
Tofadoz Tablet should not be taken along with tocilizumab as it might increase the risk of infections. Before starting Tofadoz Tablet , inform the doctor if you are taking tocilizumab.
Prior to starting Tofadoz Tablet , active or latent tuberculosis test, CBC (complete blood count), LFT (liver function test), and lipid profile tests should be done.
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