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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Tofatop XR Tablet 10's is used to treat rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis. It contains Tofacitinib which works by lowering inflammation and symptoms associated with arthritis. In some cases, this medicine may cause side effects such as diarrhoea, headache, upper respiratory tract infection, nausea, and vomiting. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Composition :

TOFACITINIB-11MG

Manufacturer/Marketer :

Alkem Laboratories Ltd

Consume Type :

Oral

Expires on or after :

Return Policy :

Not Returnable

About Tofatop XR Tablet 10's

Tofatop XR Tablet 10's is used to treat rheumatoid arthritis (an autoimmune disease which leads to joint pain and damage), psoriatic arthritis (an inflammatory condition of the joints), and ulcerative colitis (an inflammatory disease of the large intestine).

Tofatop XR Tablet 10's contains Tofacitinib, which works by blocking the Janus kinase enzyme, thereby lowering inflammation and symptoms associated with rheumatoid and psoriatic arthritis. 

Not everyone who is taking Tofatop XR Tablet 10's will get these side effects. In some cases, you may experience common side effects such as diarrhoea, headache, upper respiratory tract infection, cold, nausea, and vomiting. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

You can take Tofatop XR Tablet 10's with or without food. It should be swallowed as a whole with a glass of water. Do not chew, bite, crush, or break it. Your doctor will advise you on how often you should take your tablets based on your medical condition. It is always important to complete your treatment course for better results.

Avoid taking Tofatop XR Tablet 10's if you are allergic to it. Inform your doctor if you have an active infection, if you are taking immunosuppressants, medicines that affect the immune system or corticosteroids. Avoid taking Tofatop XR Tablet 10's if you are pregnant or breastfeeding. Tofatop XR Tablet 10's is not recommended for use in children below 18 years as safety and effectiveness have not been established. 

Uses of Tofatop XR Tablet 10's

Tofatop XR Tablet 10's is used in the treatment of Rheumatoid arthritis, Psoriatic arthritis, and Ulcerative colitis. The detailed uses of Tofatop XR Tablet 10's are as follows:

  • Treatment of Rheumatoid Arthritis: Tofatop XR Tablet 10's helps to manage moderate to severe rheumatoid arthritis by reducing joint pain, inflammation, and slowing disease progression.
  • Management of Psoriatic Arthritis: Tofatop XR Tablet 10's treats active psoriatic arthritis by reducing joint pain, swelling, stiffness, and improving overall joint function.
  • Treatment of Ulcerative Colitis: Tofatop XR Tablet 10's helps to induce and maintain remission in moderate to severe ulcerative colitis.

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Directions for Use

  • Tofatop XR Tablet 10's can be taken with or without food.
  • It is recommended to take Tofatop XR Tablet 10's 1-2 times a day, depending on your medical condition, or as prescribed by your doctor.
  • Swallow Tofatop XR Tablet 10's as a whole with a glass of water.
  • Do not crush, chew, or break it.

Key Benefits

  • Tofatop XR Tablet 10's belongs to a group of medicines called Janus kinase inhibitors used to treat rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis.
  • Tofatop XR Tablet 10's is indicated for patients with moderate to severe rheumatic arthritis, and psoriatic arthritis who have had intolerance or inadequate response to methotrexate or DMARDs (Disease-Modifying Anti-Rheumatic Drugs).
  • This medicine helps lower inflammation and symptoms associated with rheumatoid and psoriatic arthritis. 

How Tofatop XR Tablet 10's Works

Tofatop XR Tablet 10's contains 'Tofacitinib' which works by blocking the Janus kinase enzyme, thereby lowering inflammation and symptoms associated with rheumatoid and psoriatic arthritis.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Tofatop XR Tablet 10's

Take Tofatop XR Tablet 10's only as prescribed by the physician. Do not exceed the recommended dose, as it might cause unwanted side effects. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

  • Do not take Tofatop XR Tablet 10's if you are allergic to any of its components; if you have a severe infection, bloodstream infection, or if you have severe liver problems such as cirrhosis. 
  • Inform your doctor if you have an infection, symptoms of infection, a condition that increases chances of infection, are taking any medicines that affect the immune system; have or had a history of tuberculosis, chronic lung disease, liver problems, hepatitis B/C, cancer, inflammation/ulcers of the large intestine, or kidney problems; are planning to get vaccinated; or have heart problems, high cholesterol, high blood pressure, heart attack, diabetes, or blood clotting problems. 
  • If your white blood cell count or red blood cell count is low, avoid taking Tofatop XR Tablet 10's.
  • Inform your doctor if you notice painful blisters on the skin or if you experience breathing difficulties. Inform your doctor about your complete medical and medication history before starting treatment with Tofatop XR Tablet 10's, which helps the physician decide the best treatment plan.

Diet & Lifestyle Advise

  • Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.
  • Performing yoga may also help in improving joint flexibility and pain management.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep, as resting the muscles can help in reducing inflammation and swelling.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Acupuncture, massage and physical therapy may also be helpful.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
  • Avoid smoking and alcohol consumption.

Habit Forming

No

Therapeutic Class

[ANTIRHEUMATICS, DISEASE MODIFYING ANTIRHEUMATIC DRUGS (DMARDs)]

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Alcohol

Safe if prescribed

It is not known if alcohol interacts with Tofatop XR Tablet 10's, so please consult a doctor.

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Pregnancy

Consult your doctor

Tofatop XR Tablet 10's must not be taken during pregnancy. If you are a woman of child-bearing potential, use effective contraception during the treatment with Tofatop XR Tablet 10's and for 4 weeks after discontinuation.

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Breast Feeding

Consult your doctor

Avoid breastfeeding while taking Tofatop XR Tablet 10's. Please consult a doctor if you have any concerns.

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Driving

Safe if prescribed

Tofatop XR Tablet 10's generally does not affect your ability to drive. However, drive or operate machinery only if you are alert.

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Liver

Consult your doctor

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this. Tofatop XR Tablet 10's is not recommended for patients with severe liver problems.

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Kidney

Consult your doctor

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Safe if prescribed

Tofatop XR Tablet 10's is not recommended for children below 18 years as safety and effectiveness were not established.

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Heart

No serious side effects were observed. But it requires careful consideration and monitoring due to increased risks of heart-related problems, particularly in patients with existing cardiovascular risk factors.

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Geriatrics

Consult your doctor

No serious adverse effects were observed; however, it requires careful consideration and caution due to the increased risk of certain adverse events, particularly infections.

FAQs

Country of origin

India

Manufacturer/Marketer address

Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.
Other Info - TOF0144

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