Tofe-ER Tablet 10's
MRP ₹330
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₹49.5 Cashback (15%)
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About Tofe ER Tablet
Tofe ER Tablet is used to treat rheumatoid arthritis (an autoimmune disease which leads to joint pain and damage), psoriatic arthritis (an inflammatory condition of the joints), and ulcerative colitis (an inflammatory disease of the large intestine).
Tofe ER Tablet contains Tofacitinib, which works by blocking the Janus kinase enzyme, thereby lowering inflammation and symptoms associated with rheumatoid and psoriatic arthritis.
Not everyone who is taking Tofe ER Tablet will get these side effects. In some cases, you may experience common side effects such as diarrhoea, headache, upper respiratory tract infection, cold, nausea, and vomiting. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
You can take Tofe ER Tablet with or without food. It should be swallowed as a whole with a glass of water. Do not chew, bite, crush, or break it. Your doctor will advise you on how often you should take your tablets based on your medical condition. It is always important to complete your treatment course for better results.
Avoid taking Tofe ER Tablet if you are allergic to it. Inform your doctor if you have an active infection, if you are taking immunosuppressants, medicines that affect the immune system or corticosteroids. Avoid taking Tofe ER Tablet if you are pregnant or breastfeeding. Tofe ER Tablet is not recommended for use in children below 18 years as safety and effectiveness have not been established.
Uses of Tofe ER Tablet
Tofe ER Tablet is used in the treatment of Rheumatoid arthritis, Psoriatic arthritis, and Ulcerative colitis. The detailed uses of Tofe ER Tablet are as follows:
- Treatment of Rheumatoid Arthritis: Tofe ER Tablet helps to manage moderate to severe rheumatoid arthritis by reducing joint pain, inflammation, and slowing disease progression.
- Management of Psoriatic Arthritis: Tofe ER Tablet treats active psoriatic arthritis by reducing joint pain, swelling, stiffness, and improving overall joint function.
- Treatment of Ulcerative Colitis: Tofe ER Tablet helps to induce and maintain remission in moderate to severe ulcerative colitis.
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Directions for Use
- Tofe ER Tablet can be taken with or without food.
- It is recommended to take Tofe ER Tablet 1-2 times a day, depending on your medical condition, or as prescribed by your doctor.
- Swallow Tofe ER Tablet as a whole with a glass of water.
- Do not crush, chew, or break it.
Medicinal Benefits
- Tofe ER Tablet belongs to a group of medicines called Janus kinase inhibitors used to treat rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis.
- Tofe ER Tablet is indicated for patients with moderate to severe rheumatic arthritis, and psoriatic arthritis who have had intolerance or inadequate response to methotrexate or DMARDs (Disease-Modifying Anti-Rheumatic Drugs).
- This medicine helps lower inflammation and symptoms associated with rheumatoid and psoriatic arthritis.
How Tofe ER Tablet Works
Storage
- Practice good hygiene by washing hands frequently when touching any wounds.
- Apply creams or lotions to the dry skin and moisturize it.
- Wear the proper clothing and footwear when working outside.
- Cover the wounds with bandage and change it daily.
- Avoid baths at swimming pools, lakes and rivers.
- Inform your doctor about the medication you're taking and the UTI symptoms you're experiencing.
- Your doctor may adjust your medication regimen or consider alternative medications or dosages that may reduce the risk of UTIs.
- Drink plenty of water (at least 8-10 glasses a day) to help flush out bacteria. Avoid sugary drinks and caffeine, which can exacerbate UTI symptoms.
- Urinate when you feel the need rather than holding it in. This can help prevent bacterial growth and reduce the risk of UTIs.
- Consider cranberry supplements: Cranberry supplements may help prevent UTIs by preventing bacterial adhesion.
- Monitor UTI symptoms and report any changes to your doctor.
- If antibiotics are prescribed, take them as directed and complete the full course.
- Drink a lot of water to control diarrhoea and prevent dehydration.
- Avoid spicy, fatty, or high-fiber foods that may irritate the colon.
- Reduce stress through methods such as deep breathing or meditation.
- Include probiotics or supplements containing live bacteria to maintain the health of the gut.
- Quit smoking since smoking makes colitis symptoms worse.
- See your doctor right away if you experience extreme inflammation, bleeding stools, or abdominal pain.
- Inform your doctor about the common cold symptoms you're experiencing due to medication.
- Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
- Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
- Drink plenty of fluids, such as warm water or soup, to help thin out mucus.
- Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.
- To promote overall health, drink plenty of water and consume hydrating foods like watermelon and leafy greens.
- Support gut health with probiotic-rich foods such as yoghurt and sauerkraut.
- Eat antioxidant-rich foods like berries and green tea, while limiting sugary drinks, alcohol, and processed foods.
- Additionally, reduce stress through relaxation techniques like deep breathing and meditation.
- Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
- Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
- Protect your skin from extreme heat and try to apply wet compresses.
- Soak in the cool bath, which gives a soothing impact to the affected area.
What if I have taken an overdose of Tofe ER Tablet
Drug Warnings
- Do not take Tofe ER Tablet if you are allergic to any of its components; if you have a severe infection, bloodstream infection, or if you have severe liver problems such as cirrhosis.
- Inform your doctor if you have an infection, symptoms of infection, a condition that increases chances of infection, are taking any medicines that affect the immune system; have or had a history of tuberculosis, chronic lung disease, liver problems, hepatitis B/C, cancer, inflammation/ulcers of the large intestine, or kidney problems; are planning to get vaccinated; or have heart problems, high cholesterol, high blood pressure, heart attack, diabetes, or blood clotting problems.
- If your white blood cell count or red blood cell count is low, avoid taking Tofe ER Tablet .
- Inform your doctor if you notice painful blisters on the skin or if you experience breathing difficulties. Inform your doctor about your complete medical and medication history before starting treatment with Tofe ER Tablet , which helps the physician decide the best treatment plan.
Drug-Drug Interactions
Drug-Drug Interactions
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Using Tofe-ER Tablet together with antithymocyte globulin can increase the risk of serious infections.
How to manage the interaction:
Taking Antithymocyte Globulin with Tofe-ER Tablet together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, pain or burning during urination contact your doctor. Do not discontinue any medications without consulting your doctor.
When Tofe-ER Tablet is taken with Daunorubicin, it may increase the risk of infection.
How to manage the interaction:
Although there is a possible interaction between Tofe-ER Tablet and Daunorubicin, you can take these medicines together if prescribed by your doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without first consulting your doctor.
The combined use of Tofe-ER Tablet and Hydrocortisone can increase the risk of infections and gastrointestinal bleeding or perforation.
How to manage the interaction:
Co-administration of Tofe-ER Tablet and hydrocortisone can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, severe abdominal pain, nausea, or vomiting, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
Co-administration of Deflazacort with Tofe-ER Tablet may increase the risk of serious infections.
How to manage the interaction:
Although there is a possible interaction between Deflazacort and Tofe-ER Tablet, you can take these medicines together if prescribed by your doctor. If you have any of the symptoms like fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, and pain or burning when you urinate, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
Co-administration of Tofe-ER Tablet and Prednisolone can increase the risk of serious infections, diverticular disease (development of small bulges in the lining of the intestine), or gastrointestinal bleeding or perforation.
How to manage the interaction:
Although taking Tofe-ER Tablet and Prednisolone together can result in an interaction, it can be taken if a doctor has prescribed it. If you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in the coughing fluid, weight loss, red or inflamed skin, body sores, pain or burning when urinating, severe abdominal pain, fever, nausea, or vomiting, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
Coadministration of Tofe-ER Tablet with Sirolimus may increase the risk or severity of developing infection.
How to manage the interaction:
Although there is a possible interaction between Sirolimus and Tofe-ER Tablet, you can take these medicines together if prescribed by a doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
Combining Infliximab with Tofe-ER Tablet can lead to or increase the risk or severity of developing serious infections.
How to manage the interaction:
Although taking Tofe-ER Tablet and Infliximab together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience symptoms of fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in sputum, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Taking Tofe-ER Tablet and Mercaptopurine increases the risk of infection.
How to manage the interaction:
Although there is a possible interaction between Mercaptopurine and Tofe-ER Tablet, you can take these medicines together if prescribed by your doctor. If you experience any of these symptoms - serious infections, complications, fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, or pain or burning when you pee - contact your doctor right away. Do not stop using any medications without talking to a doctor.
When Tofe-ER Tablet is taken with Saquinavir, it may increase the risk of side effects..
How to manage the interaction:
There may be a possibility of interaction between Tofe-ER Tablet and Saquinavir, but it can be taken if prescribed by a doctor. However, consult the doctor immediately if you experience symptoms such as paleness, fatigue, dizziness, fainting, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without first talking to your doctor.
Taking Etanercept with Tofe-ER Tablet can increase the risk of serious infections as well as sometimes may lead to cancers.
How to manage the interaction:
Although there is a possible interaction between Tofe-ER Tablet and Etanercept, you can take these medicines together if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medications without talking to a doctor.
Drug-Food Interactions
Drug-Food Interactions
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Grapefruit, Grapefruit Juice
How to manage the interaction:
Consuming grapefruit products while taking Tofe-ER Tablet can increase the risk of side effects. Avoid consuming grapefruit products while being treated with Tofe-ER Tablet, as it can lead to an interaction.
Diet & Lifestyle Advise
- Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.
- Performing yoga may also help in improving joint flexibility and pain management.
- Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
- Get adequate sleep, as resting the muscles can help in reducing inflammation and swelling.
- De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
- Acupuncture, massage and physical therapy may also be helpful.
- Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
- Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
- Avoid smoking and alcohol consumption.
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Alcohol
Caution
It is not known if alcohol interacts with Tofe ER Tablet , so please consult a doctor.
Pregnancy
Unsafe
Tofe ER Tablet must not be taken during pregnancy. If you are a woman of child-bearing potential, use effective contraception during the treatment with Tofe ER Tablet and for 4 weeks after discontinuation.
Breast Feeding
Unsafe
Avoid breastfeeding while taking Tofe ER Tablet . Please consult a doctor if you have any concerns.
Driving
Safe
Tofe ER Tablet generally does not affect your ability to drive. However, drive or operate machinery only if you are alert.
Liver
Caution
Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this. Tofe ER Tablet is not recommended for patients with severe liver problems.
Kidney
Caution
Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.
Children
Unsafe
Tofe ER Tablet is not recommended for children below 18 years as safety and effectiveness were not established.
Heart
No serious side effects were observed. But it requires careful consideration and monitoring due to increased risks of heart-related problems, particularly in patients with existing cardiovascular risk factors.
Geriatrics
Caution
No serious adverse effects were observed; however, it requires careful consideration and caution due to the increased risk of certain adverse events, particularly infections.
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