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compositionComposition:TOFISOPAM-50MG
prescription
Prescription Medicine
info
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Toficalm 50 Tablet is used to treat depression and associated anxiety with depression. It contains Tofisopam, which reduces tension, creates a feeling of well-being, relieves anxiety, helps you sleep better, and increases your energy levels so that you can perform daily activities. It may cause side effects such as loss of appetite, dryness in the mouth, nausea, insomnia (difficulty in sleeping), and headache. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

TOFISOPAM-50MG

Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Toficalm 50 Tablet

Toficalm 50 Tablet is an oral prescription medicine primarily used to treat various forms of anxiety, depression, and associated physical symptoms. It helps manage emotional distress and autonomic nervous system symptoms, such as sweating or a racing heart, that are triggered by mental strain. This medicine is designed to help you regain mental calmness and stability so you can manage your daily routine more comfortably.

To get the best results, you must take Toficalm 50 Tablet consistently and exactly as prescribed by your doctor. It can be taken with or without food, but keeping your daily routine uniform helps maintain stable levels of the medicine in your body. Simple lifestyle adjustments, such as practising deep-breathing exercises and reducing your daily intake of caffeine, can also support your progress.

While taking Toficalm 50 Tablet , you might experience mild side effects like a dry mouth, mild headache, or nausea. These symptoms are usually temporary, but if you notice severe allergic reactions or signs of liver damage, you should consult your doctor immediately.

Talk to your doctor before starting Toficalm 50 Tablet if you have a history of breathing difficulties, severe lung conditions, or muscle weakness. Do not take this if you have had a severe allergic reaction to this medicine or similar medications in the past.

This medicine can interact with other substances, including alcohol and medications that affect your central nervous system or liver enzymes. If you are pregnant, planning to become pregnant, breastfeeding, or are an elderly individual, always consult your healthcare provider before taking this medicine.

Uses of Toficalm 50 Tablet

Toficalm 50 Tablet is used in the treatment of anxiety and depression. The detailed uses of Toficalm 50 Tablet are as follows:

  • Anxiety disorders: Toficalm 50 Tablet helps relieve symptoms of generalised anxiety, panic, and emotional tension by calming the nervous system without causing significant drowsiness.
  • Depression: Toficalm 50 Tablet supports mood upliftment and reduces sadness in individuals with depression.
  • Autonomic nervous system symptoms: It helps manage physical symptoms linked to anxiety, such as sweating, trembling, and a rapid heartbeat, by stabilising nerve pathways.
  • Alcohol withdrawal support: In some clinical settings, it is used to manage mild-to-moderate anxiety and irritability associated with alcohol withdrawal.

Key Benefits

Toficalm 50 Tablet helps relieve symptoms of anxiety, making it easier to stay calm and manage everyday situations with greater confidence. It can reduce feelings of nervousness, tension, and worry while helping many people stay active and alert throughout the day.

Benefits may include:

  • Helps relieve anxiety, nervousness, and emotional tension.
  • Helps improve mood and reduce feelings of sadness in people with depression.
  • Reduces physical symptoms of anxiety such as restlessness and feeling on edge.
  • Improves focus and the ability to carry out daily activities more comfortably.
  • Supports emotional well-being by promoting a greater sense of calm.
  • Promotes better social, work, and everyday functioning by easing anxiety symptoms.
  • Provides effective anxiety relief with a lower risk of dependence than many traditional benzodiazepines when used as prescribed.

Directions for Use

  • Take Toficalm 50 Tablet by mouth exactly as directed by your doctor.
  • Swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet, as this can affect how the medicine is absorbed in your body.
  • You can take this medicine with or without food. However, if it upsets your stomach, taking it with a meal can help.
  • Always follow your doctor's exact instructions regarding how often and how long to take this medication.

How Toficalm 50 Tablet Works

Toficalm 50 Tablet contains Tofisopam, which works by blocking certain enzymes called phosphodiesterases (PDE-4 and PDE-10), thereby increasing the levels of important chemical messengers inside brain cells. This helps regulate the autonomic nervous system, reducing anxiety and easing related physical symptoms. Thus, Toficalm 50 Tablet helps relieve anxiety without causing significant sleepiness, muscle relaxation, or weakness, allowing you to remain alert and active during the day.
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Alcohol

Caution

You are recommended not to consume alcohol along with Toficalm 50 Tablet to avoid unpleasant side-effects like drowsiness, dizziness, or sleepiness. It may also lead to a life-threatening condition like coma if taken with excessive alcohol.

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Pregnancy

Unsafe

Toficalm 50 Tablet is a Category D risk pregnancy drug that is considered unsafe for pregnant women. Toficalm 50 Tablet can have some harmful effects on the baby (fetus), so your doctor will weigh the benefits and any potential risks before prescribing it to you.

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Breast Feeding

Unsafe

Toficalm 50 Tablet passes into the breast milk and may cause some degree of sedation in the baby. So, keep your doctor informed if you're planning to breastfeed while on this medication.

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Driving

Unsafe

Toficalm 50 Tablet usually causes dizziness, drowsiness, and visual disturbances, which may affect their ability to drive or operate machinery. So, do not drive or operate heavy machinery if you feel sleepy or dizzy after taking Toficalm 50 Tablet . Tell your doctor if you get these types of side effects.

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Liver

Caution

Toficalm 50 Tablet to be taken with caution, especially if you have a history of Liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Toficalm 50 Tablet to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Unsafe

It is unknown whether Toficalm 50 Tablet is safe or effective in treating conditions like panic disorder in children younger than 18 years old. So, your doctor will decide whether Toficalm 50 Tablet can be given to children less than 18 years of age or not.

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Heart

Safe if prescribed

Due to its cardioprotective actions, Toficalm 50 Tablet is safe for use in heart patients if prescribed by the physician.

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Geriatrics

Caution

Toficalm 50 Tablet should be used under caution in geriatric patients. Please consult your physician.

What if I have taken an overdose of Toficalm 50 Tablet

If you suspect an overdose, seek immediate medical attention or call your local poison control centre. Symptoms of an overdose may include extreme drowsiness, confusion, or severe dizziness.

Diet & Lifestyle Advise

  • Limit caffeine intake: Avoid or reduce drinks and foods containing caffeine, as they may worsen anxiety symptoms and reduce the calming benefits of Toficalm 50 Tablet .
  • Practice relaxation techniques: Include activities such as deep breathing, yoga, or progressive muscle relaxation in your daily routine to help manage stress and support emotional well-being.
  • Maintain a regular sleep schedule: Go to bed and wake up at the same time each day to support your nervous system and help reduce anxiety over time.
  • Avoid alcohol: Do not drink alcohol while taking this medicine, as it may interact with the medication, worsen anxiety, or increase the risk of unwanted side effects.

Health Queries

I am taking Toficalm and Thealife, but I am experiencing a pricking sensation in my head and throbbing in my left hand. Are these symptoms side effects of these medications, and what should I do?

Vikas Singh

Vikas Singh

M Pharmacy

The sensations you are experiencing, such as pricking in your head and throbbing in your left hand, are not common side effects of Toficalm (tofisopam) or L-theanine. Sometimes, mild sensory changes can occur as your body adjusts to anxiety treatments, or these sensations could be physical manifestations of anxiety itself. Please do not panic, as these symptoms are often temporary and manageable. However, because throbbing in the left hand can occasionally be linked to circulation or nerve irritation, it is best to consult your doctor. They can safely evaluate these symptoms and adjust your therapy if needed. Please do not stop your medication without medical guidance.

I am suffering from depression. Can I take Toficalm 50 Tablet to treat it?

Chandrakanta Jena

Chandrakanta Jena

Pharm D

Toficalm 50 Tablet contains Tofisopam, which is mainly used to manage anxiety rather than treat depression. It is not considered a first-line medication for treating depressive disorders. In some cases, it may be prescribed if anxiety symptoms are present along with depression, but this should only be decided by a doctor. Depression is usually treated with antidepressant medications and psychological therapies, depending on the severity. Please avoid self-medicating and consult a doctor or psychiatrist for a proper assessment before starting any medication, especially if your symptoms are worsening or affecting daily life.
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Have a query?

How Soon It Starts Working

  • The time required for Toficalm 50 Tablet to start to work: Toficalm 50 Tablet ideally shows its action within 2 hours after administration.
  • The time for which the effects of Toficalm 50 Tablet last: The effect of Toficalm 50 Tablet lasts for 6 hours.

What if you forget to take Toficalm 50 Tablet

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular schedule. Do not take a double dose to make up for a missed one.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Check your alertness: Before driving, riding a bike, or operating machinery, see how this medicine affects you. Although Toficalm 50 Tablet is less likely to cause drowsiness than many anti-anxiety medicines, it can affect some people differently.
  • Avoid alcohol: Do not drink alcohol while taking this medicine. Alcohol may increase side effects or cause unexpected reactions.
  • Tell your doctor about breathing problems: Inform your doctor if you have severe lung disease or difficulty breathing before starting this medicine. They will decide if it is safe for you.
  • Do not stop the medicine suddenly: Continue taking this medicine exactly as prescribed, even if you start feeling better. Speak with your doctor before stopping it, as they will advise you on the safest way to discontinue treatment.
  • Share your medicine list: Tell your doctor about all the medicines, supplements, and herbal products you are taking. This is especially important for medicines that affect the brain or liver, as they may interact with Toficalm 50 Tablet .
  • Discuss certain health conditions: Tell your doctor if you have severe liver disease or acute narrow-angle glaucoma before taking this medicine. Toficalm 50 Tablet may not be suitable for people with these conditions.
  • Attend follow-up appointments: Keep your scheduled doctor visits so your treatment can be reviewed. Your doctor will check how well the medicine is working, monitor for side effects, and adjust your dose if needed.
  • Report ongoing or worsening symptoms: Contact your doctor if your anxiety does not improve within a few weeks, gets worse, or if side effects become troublesome. Your treatment may need to be reviewed or adjusted.

Drug-Drug Interactions

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Drug-Drug Interaction:

  • Central Nervous System Depressants (e.g., zolpidem, alprazolam, morphine, tramadol): Taking these medicines alongside Toficalm 50 Tablet may increase the risk of drowsiness, dizziness, and coordination problems.
  • Liver Enzyme Inhibitors (e.g., ketoconazole, erythromycin): These medicines may slow the breakdown of Toficalm 50 Tablet , increasing its levels in the body and the risk of side effects.

Drug-Food Interaction:

  • Alcohol: Avoid alcohol, as it can modify the effects of Toficalm 50 Tablet and worsen your symptoms or cause unexpected side effects.

Drug-Disease Interaction:

  • Myasthenia Gravis: Use with caution, as neuromuscular conditions may be affected by medications acting on the nervous system.
  • Severe Respiratory Insufficiency: Do not take this if you have severe breathing problems, as it may worsen respiratory function.
  • Liver or Kidney Disease: If you have liver or kidney issues, your body may process Toficalm 50 Tablet more slowly, requiring careful monitoring by your doctor.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

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All Substitutes & Brand Comparisons

Habit Forming

Yes

Therapeutic Class

[ANXIOLYTICS]

FAQs

Toficalm 50 Tablet is used to treat depression and associated anxiety with depression.
Toficalm 50 Tablet contains Tofisopam (benzodiazepine), which is used to treat anxiety. Tofisopam works by increasing the action of a chemical messenger GABA, which suppresses the excessive and abnormal activity of nerve cells in the brain.
Do not abruptly stop taking Toficalm 50 Tablet as it might lead to nausea, aggressive behavior, anxiety, confusion. Inform your doctor if you feel better, and accordingly, the dose will be adjusted.
Toficalm 50 Tablet is generally not recommended for elderly patients as it is known to reduce muscle tone and increase the risk of falls. So, if a doctor prescribes it, only then take it.
Yes, Toficalm 50 Tablet may cause mental or physical dependence if used for a prolonged time. Therefore, take Toficalm 50 Tablet only in dose and duration as advised by your doctor.
If you have taken a double dose or overdose of Toficalm 50 Tablet , you need immediate medical help either by calling a doctor or going to the nearest hospital or clinic.
Caffeine is a stimulant that may reduce the calming effects of tofisopam. So, it is advisable to avoid the intake of caffeinated beverages like coffee, tea, and cola, or chocolate that contain caffeine.
Toficalm 50 Tablet may cause common side effects, such as loss of appetite, dryness in the mouth, nausea, insomnia (difficulty in sleeping), and headache. Most of these side effects of Toficalm 50 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
Yes, Toficalm 50 Tablet has a very high potential for habit formation, so it should only be taken in the dose and duration prescribed by your doctor. Do not stop taking Toficalm 50 Tablet abruptly, as this may lead to withdrawal symptoms such as nausea, aggression, anxiety, and confusion. Inform your doctor if you notice any unusual symptoms, as your dosage may need to be adjusted accordingly.
Toficalm 50 Tablet should be used cautiously in elderly patients due to their potential to reduce muscle tone, which may increase the risk of falls and related injuries. It is generally not recommended unless prescribed by a doctor who can carefully assess the benefits and risks for the individual patient.
Unlike traditional anti-anxiety medications, Toficalm 50 Tablet does not typically cause significant drowsiness or sleepiness because of how it works in the brain. However, individual reactions can vary, so talk to your doctor if you feel unusually tired.
No, you should avoid drinking alcohol while taking Toficalm 50 Tablet , as it can interact unpredictably and cause unwanted side effects or worsen your anxiety.
Although Toficalm 50 Tablet does not usually cause sedation, you should see how it affects you before driving or operating heavy machinery. Talk to your doctor if you experience any dizziness.
Dry mouth is a common, mild side effect. Sucking on sugarless hard candy, chewing sugarless gum, or drinking plenty of water can help relieve this. If it persists, talk to your doctor or pharmacist.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

90, Delhi - Jaipur Road, Sector 32, Gurugram, Haryana 122001.
Other Info - TOF0024

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