apollo
logo
0

Welcome User

Login/Sign Up

Home
Buy Medicines
Lab Tests
Doctor Consult
Circle Membership
insurance
Blogs
Contact Us
Privacy Policy
Return & Refunds
Need Help
Terms and Conditions
Select Delivery Location
image icons

Tofocom 200 mg/300 mg Tablet belongs to the class of antiretroviral drugs used in the treatment of HIV infection. This combination medicine work by inhibiting the reverse transcriptase enzyme production, which is necessary for the multiplication of the viruses. Common side effects include dizziness, headache, diarrhoea, nausea, vomiting, rashes, and feeling weak

Read more
Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
OffersOffers & Discounts

Get Free delivery (₹99) with circle icon

Join Circle
Get 18% Off with Coupons
Extra 10% Off with Bank Offers
bank offer
bank offer
bank offer

More about the Product

Composition :

EMTRICITABINE-200MG+TENOFOVIR DISOPROXIL FUMARATE-300MG

Manufacturer/Marketer :

Alkem Laboratories Ltd

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Tofocom 200 mg/300 mg Tablet

Tofocom 200 mg/300 mg Tablet is a prescription oral tablet used to treat human immunodeficiency virus type 1 (HIV-1) in combination with other antiretroviral medicines. It is also prescribed as Pre-Exposure Prophylaxis (PrEP) to reduce the risk of acquiring HIV-1 infection in individuals who are at high risk. By keeping the virus from multiplying, this medicine helps manage the infection and protects the immune system.

To achieve the best results, you must take Tofocom 200 mg/300 mg Tablet consistently every single day, exactly as your doctor directs. You can take this tablet with or without food, making it easy to fit into your daily routine. Eating a balanced diet and staying physically active can support your overall immune system while you are on this medication.

While taking Tofocom 200 mg/300 mg Tablet, some people may experience mild side effects like nausea, headache, or trouble sleeping. However, you should contact your healthcare provider immediately if you notice serious signs such as severe tiredness, deep breathing, or yellowing of your skin and eyes, which could indicate liver damage.

Do not take this if you have not been confirmed HIV-negative and are planning to use it for prevention, as this can make the virus harder to treat later. It is also important to talk to your doctor before starting this medicine if you have any history of kidney disease or bone thinning.

Before starting Tofocom 200 mg/300 mg Tablet, your doctor may recommend blood tests to check for hepatitis B virus (HBV) and assess your kidney function. Because this medicine is also active against HBV, stopping treatment if you have undiagnosed chronic hepatitis B can cause a serious worsening of liver disease. These tests help your doctor determine whether this medicine is suitable for you. This medicine can interact with other drugs that affect your kidneys, so you should share a complete list of all your medications with your doctor. If you are pregnant, breastfeeding, or planning a family, talk to your doctor or pharmacist to understand how to safely use this medicine.

Uses of Tofocom 200 mg/300 mg Tablet

Tofocom 200 mg/300 mg Tablet is used in the treatment and prevention of HIV (human immunodeficiency virus) infection. The detailed uses of Tofocom 200 mg/300 mg Tablet are as follows:

  • HIV-1 Infection Treatment: Works alongside other antiretroviral medications to control the virus, lower the viral load, and help the immune system recover.
  • HIV-1 Pre-Exposure Prophylaxis (PrEP): Helps prevent getting HIV-1 through sexual contact in individuals who are at high risk of exposure.

Key Benefits

Tofocom 200 mg/300 mg Tablet helps treat HIV-1 infection and, when used as prescribed, can also help prevent HIV-1 infection in people at risk. The following are the benefits of this medication:

  • Helps reduce the amount of HIV-1 in the body to very low or undetectable levels.
  • Supports a healthy immune system and reduces the risk of HIV-related infections and complications.
  • Helps strengthen and protect the immune system by controlling HIV-1.
  • Reduces the risk of severe infections and HIV-related complications.
  • Provides highly effective protection against HIV-1 infection when taken consistently as pre-exposure prophylaxis (PrEP).
  • Supports long-term HIV management and proactive HIV prevention when used with recommended medical care.
Side effects of Tofocom 200 mg/300 mg Tablet
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Managing back pain as a side effect of medication requires a combination of self-care techniques, lifestyle modifications, and medical interventions. Here are the steps:
  • Talk to your doctor about your back pain and potential medication substitutes or dose changes.
  • Try yoga or Pilates and other mild stretching exercises to increase flexibility and strengthen your back muscles.
  • To lessen the tension on your back, sit and stand upright and maintain proper posture.
  • To alleviate discomfort and minimize inflammation, apply heat or cold packs to the afflicted area.
  • Under your doctor's supervision, think about taking over-the-counter painkillers like acetaminophen or ibuprofen.
  • Make ergonomic adjustments to your workspace and daily activities to reduce strain on your back.
  • To handle tension that could make back pain worse, try stress-reduction methods like deep breathing or meditation.
  • Use pillows and a supportive mattress to keep your spine in the right posture as you sleep.
  • Back discomfort can worsen by bending, twisting, and heavy lifting.
  • Speak with a physical therapist to create a customized training regimen to increase back strength and flexibility.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Directions for Use

  • Tofocom 200 mg/300 mg Tablet can be taken with or without food, or as advised by a doctor.
  • It is usually recommended to be taken once a day. However, follow your doctor's instructions regarding dosage and timing for optimal results.
  • Swallow Tofocom 200 mg/300 mg Tablet as a whole with a glass of water.
  • Do not crush, chew, or break it.

How Tofocom 200 mg/300 mg Tablet Works

Tofocom 200 mg/300 mg Tablet is an antiretroviral medicine that contains two active components that work together to fight HIV. Emtricitabine: It is a nucleoside reverse transcriptase inhibitor (NRTI). It blocks the reverse transcriptase enzyme that HIV needs to make copies of itself, helping prevent the virus from multiplying. Tenofovir disoproxil fumarate: It is a nucleotide reverse transcriptase inhibitor (NtRTI). It also blocks the reverse transcriptase enzyme, stopping HIV from replicating and spreading in the body. It works together with emtricitabine to help control the infection, protect the immune system, and reduce the risk of HIV-related complications.
bannner image

Alcohol

Caution

It is not known whether Tofocom 200 mg/300 mg Tablet interacts with alcohol. Please consult your doctor.

bannner image

Pregnancy

Caution

Please consult your doctor if you have any concerns regarding this, your doctor will prescribe only if the benefits outweigh the risks.

bannner image

Breast Feeding

Unsafe

Avoid breastfeeding while taking Tofocom 200 mg/300 mg Tablet as it may pass into breastmilk.

bannner image

Driving

Caution

Tofocom 200 mg/300 mg Tablet may cause dizziness. So, drive or operate machinery only if you are alert.

bannner image

Liver

Caution

Dose adjustment may be needed. Please consult your doctor before taking Tofocom 200 mg/300 mg Tablet if you have a liver impairment or any concerns regarding this.

bannner image

Kidney

Caution

Dose adjustment may be needed. Please consult your doctor before taking Tofocom 200 mg/300 mg Tablet if you have kidney impairment or any concerns regarding this.

bannner image

Children

Unsafe

Tofocom 200 mg/300 mg Tablet is not recommended for children below 12years.

bannner image

Heart

Consult your doctor

Let your doctor know if you have any history of heart problems. Your doctor will weigh the benefits and potential risks before prescribing Tofocom 200 mg/300 mg Tablet.

bannner image

Geriatrics

Caution

Tofocom 200 mg/300 mg Tablet should be given with caution in elderly patients due to an increased risk of side effects. Please consult your doctor before using Tofocom 200 mg/300 mg Tablet.

What if I have taken an overdose of Tofocom 200 mg/300 mg Tablet

In case of an accidental overdose, seek immediate medical attention or call your local poison control centre right away.

Diet & Lifestyle Advise

  • Support bone health: Since this medicine can affect bone density, ensure your diet includes plenty of calcium and Vitamin D, or ask your doctor about appropriate supplements.
  • Protect your kidneys: Stay well-hydrated by drinking plenty of water daily to help your kidneys clear the medicine efficiently.
  • Practice safe sex: If using this medicine for prevention (PrEP), remember that it does not protect against other sexually transmitted infections (STIs). Combine it with consistent condom use and regular screening.
  • Maintain regular testing: Attend all scheduled appointments for blood tests to monitor your kidney function, liver health, HIV status, and viral load. If you are receiving HIV treatment, your doctor will also regularly monitor your CD4 cell count and viral load to assess how well the treatment is working and how your immune system is recovering.
health query

Have a query?

How Soon It Starts Working

The time required for Tofocom 200 mg/300 mg Tablet to start to work: The time required for Tofocom 200 mg/300 mg Tablet to show its action is unknown. The time for which the effects of Tofocom 200 mg/300 mg Tablet last: The duration of action for Tofocom 200 mg/300 mg Tablet is clinically unknown.

What if you forget to take Tofocom 200 mg/300 mg Tablet

If you miss a dose, take it as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose and resume your regular dosing schedule. Do not take two doses at once to make up for a missed one.

Storage

•Store Tofocom 200 mg/300 mg Tablet tablets at room temperature between 20°C to 25°C (68°F to 77°F).• Keep the tablets in their original bottle, and do not remove the small drying packet (desiccant) inside, as it protects the medicine from moisture.

Drug Warnings

  • Verify your HIV status: If you are taking Tofocom 200 mg/300 mg Tablet for PrEP, get tested for HIV before starting treatment and at least every 3 months. Taking this medicine alone when you already have HIV can make the virus harder to treat.
  • Do not stop the medicine on your own: Do not stop taking Tofocom 200 mg/300 mg Tablet without talking to your doctor. If you have hepatitis B, stopping the medicine suddenly can cause a serious worsening of your liver disease.
  • Get tested for hepatitis B: Your doctor may test you for hepatitis B before starting treatment. If you have a hepatitis B infection, follow your doctor's advice carefully and do not stop the medicine without medical guidance.
  • Be careful with kidney-affecting medicines: Talk to your doctor or pharmacist before taking pain relievers such as ibuprofen or naproxen, or other medicines that may affect your kidneys. Using them together may increase the risk of kidney problems.
  • Check the medicine before use: Make sure the bottle's protective seal is intact before opening it. Do not use the tablets if the seal is broken or missing.

Drug-Drug Interactions

verifiedApollotooltip
  • Kidney-damaging drugs (e.g., ibuprofen, ganciclovir, cidofovir): Taking this medicine with other drugs that affect kidney function, such as certain antivirals or high-dose NSAID pain relievers, can increase the risk of kidney problems.
  • Other HIV medications (e.g. ritonavir, darunavir): Avoid taking this medicine alongside other drugs containing the same active components to prevent accidental overdose or increased side effects.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

Login/Sign Up

Drug-Food Interactions

verifiedApollotooltip

No clinically significant food or drink interactions are known with Tofocom 200 mg/300 mg Tablet.

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

Login/Sign Up

All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIRETROVIRAL AGENTS]

FAQs

Tofocom 200 mg/300 mg Tablet belongs to a group of antiretroviral medicines used to treat HIV infection. Tofocom 200 mg/300 mg Tablet helps decrease the chance of developing AIDS (acquired immunodeficiency syndrome) and other HIV-related illnesses.
Tofocom 200 mg/300 mg Tablet is a combination of two drugs: Emtricitabine and Tenofovir disoproxil fumarate. Tofocom 200 mg/300 mg Tablet works by interfering with the working of nucleotide and nucleoside reverse transcriptase enzymes necessary for the reproduction of the virus. Together, Tofocom 200 mg/300 mg Tablet helps in treating HIV infection.
Please do not stop taking Tofocom 200 mg/300 mg Tablet without consulting your doctor, as it may reduce the effectiveness of anti-HIV therapy. Continue taking Tofocom 200 mg/300 mg Tablet for as long as your doctor has prescribed it to treat your condition effectually. Do not be reluctant to speak with your doctor if you experience any difficulty taking Tofocom 200 mg/300 mg Tablet.
Tofocom 200 mg/300 mg Tablet might cause lactic acidosis (excess of lactic acid in the blood), a rare but severe side effect, especially in women who are obese and people with liver disease. Consult a doctor immediately if you experience stomach pain, vomiting, nausea, drowsiness, and deep rapid breathing while taking Tofocom 200 mg/300 mg Tablet.
HIV negative patients can take Tofocom 200 mg/300 mg Tablet to lower the chance of getting HIV infection if prescribed by the doctor. Before starting the treatment, you should have a negative HIV test and whilst taking Tofocom 200 mg/300 mg Tablet regular HIV tests for at least every 3months is advised.
Tofocom 200 mg/300 mg Tablet may cause bone problems such as soft bones, thin bones, and bone pain. A regular bone density test is advised while taking Tofocom 200 mg/300 mg Tablet. For good bone health, take calcium and vitamin D supplements as told by the doctor.
Yes, you can take Tofocom 200 mg/300 mg Tablet with or without food. Taking it at the same time every day is what matters most for its effectiveness. Talk to your doctor if you experience nausea when taking it on an empty stomach.
If you vomit within 1 hour of taking your tablet, you should take another dose. If you vomit more than 1 hour after taking it, you do not need to take another dose. Talk to your doctor or pharmacist if this happens frequently.
No, Tofocom 200 mg/300 mg Tablet only helps prevent or treat HIV-1. It does not protect against other STIs like syphilis, chlamydia, or gonorrhoea. Talk to your doctor about comprehensive safe sex practices.
You should consult your healthcare provider to discuss the benefits and risks. Many pregnant individuals safely take this medication, but it is important to have a personalised clinical plan. Talk to your doctor for guidance.
It is critical to confirm you are HIV-negative before and during PrEP use. If you acquire HIV while taking only Tofocom 200 mg/300 mg Tablet, the virus can become resistant to the medication, making future treatment more difficult. Talk to your doctor about your testing schedule.
There is no direct chemical interaction between alcohol and Tofocom 200 mg/300 mg Tablet. However, heavy alcohol use can put extra stress on your liver and may make it harder to remember to take your dose on time. Talk to your doctor about your alcohol intake.
No, Tofocom 200 mg/300 mg Tablet does not cure HIV-1 infection. It is a chronic treatment that controls the virus, reduces viral load, and helps you maintain a healthy immune system. Talk to your doctor about long-term management.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Electronic Medicines Compendium (EMC). Pil.9028 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  2. Drugs.com Clinical Review Team. Emtricitabine And Tenofovir Disoproxil Fumarate Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  3. MedlinePlus. A612036 Patient Information Monograph. Bethesda, MD: U.S. National Library of Medicine (NLM); 2025. [Accessed on 02 Jun. 2026]Check here
  4. Tenofovir disoproxil fumarate+emtricitabine [EMC Label]. 2005. [Accessed on 10 Apr. 2019]Check here
  5. Emtricitabine and tenofovir disoproxil fumarate [Prescribing Information]. 2005. [Accessed on 10 Apr. 2019]Check here
  6. Tenofovir disoproxil fumarate [Prescribing Information]. 2012. [Accessed on 10 Apr. 2019]Check here
  7. Emtricitabine and tenofovir disoproxil fumarate [Prescribing Information]. 2024. [Accessed on 10 Mar. 2025]Check here

Country of origin

India
Other Info - TO53539
whatsapp Floating Button
Buy Now
Add to Cart