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compositionComposition:OLANZAPINE-405MG
prescriptionPrescription Medicine
Tolaz LA 405mg/vial Convenience Kit 1's
Tolaz LA 405mg/vial Convenience Kit 1's
Tolaz LA 405mg/vial Convenience Kit 1's
Tolaz LA 405mg/vial Convenience Kit 1's

Tolaz LA 405mg/vial Convenience Kit is used to treat schizophrenia and bipolar I disorder. It helps improve thinking, mood, and behaviour and reduces hallucinations (seeing or hearing things that are not real) and agitation (feeling restless or very upset). It also helps control manic episodes and supports mental stability.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

OLANZAPINE-405MG

Manufacturer/Marketer :

Torrent Pharmaceuticals Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Tolaz LA 405mg/vial Convenience Kit

Tolaz LA 405mg/vial Convenience Kit is primarily used to treat schizophrenia and manic or mixed episodes of bipolar I disorder. Schizophrenia is a mental condition that causes hallucinations, false beliefs, and confusion. Bipolar I disorder causes extreme mood swings with changes in thinking and behaviour.

Tolaz LA 405mg/vial Convenience Kit contains olanzapine, which helps balance brain chemicals linked to mood and behaviour. It improves thinking and mental clarity and reduces hallucinations and agitation. It also helps control manic episodes. This supports better emotional balance and daily functioning.

Tolaz LA 405mg/vial Convenience Kit will be administered by a health care professional. Common side effects include drowsiness, dizziness, headache, dry mouth, nausea, vomiting, diarrhoea, constipation, stomach pain, back pain, runny/stuffy nose, cough, increased appetite, weight gain, and redness/pain/swelling at the injection site. If you notice any side effects that are not manageable, please consult your doctor. 

Tolaz LA 405mg/vial Convenience Kit is not recommended for treatment in patients with Dementia-Related Psychosis. If you are pregnant, planning to conceive, or breastfeeding, inform your doctor before receiving Tolaz LA 405mg/vial Convenience Kit. Tolaz LA 405mg/vial Convenience Kit is not recommended for children and adolescents under 18. However, please seek medical advice.

Uses of Tolaz LA 405mg/vial Convenience Kit

Tolaz LA 405mg/vial Convenience Kit is used in the treatment of Schizophrenia and bipolar I disorder. The detailed uses of Tolaz LA 405mg/vial Convenience Kit are as follows:

  • Schizophrenia: Tolaz LA 405mg/vial Convenience Kit helps to manage symptoms of schizophrenia, such as hallucinations, delusions, and disorganised thinking, improving overall quality of life.
  • Bipolar I Disorder: Tolaz LA 405mg/vial Convenience Kit is used to manage manic or mixed episodes, helping to stabilise mood and reduce symptoms.

Have a query?

Directions for Use

  • Your doctor will determine the dosage and frequency depending on your condition.
  • Tolaz LA 405mg/vial Convenience Kit will be administered by a healthcare professional.
  • Do not self-administer.

Key Benefits

Tolaz LA 405mg/vial Convenience Kit, when used as prescribed, may provide the following benefits:

For Schizophrenia:

  • Helps reduce hallucinations, delusions, and disturbed thinking.
  • Improves clarity of thoughts and daily functioning.
  • Promotes better emotional balance and behaviour control.

For Bipolar I Disorder:

  • Helps control manic or mixed episodes.
  • Stabilises mood and reduces extreme mood changes.
  • Helps reduce irritability and impulsive behaviour.
  • Supports long-term mental stability and well-being.

How Tolaz LA 405mg/vial Convenience Kit Works

Tolaz LA 405mg/vial Convenience Kit contains 'Olanzapine' that works by balancing brain chemicals that affect schizophrenia, helping improve thinking, behaviour, and reducing hallucinations (seeing or hearing things that are not real) and agitation (feeling restless or very upset). In manic episodes of bipolar disorder, it helps stabilise mood, control restlessness, and improve clearer thinking.

Storage

Store in a cool and dry place away from sunlight
Side effects of Tolaz LA 405mg/vial Convenience Kit
  • Exercise for at least 30 minutes most days of the week.
  • Limit alcohol consumption.
  • Consider a low carbohydrate diet that limits grains, starchy vegetables and fruit. Include foods rich in protein and fat.
  • Avoid excess sugar, fatty foods and carbohydrates.
  • Aim for weight loss as it helps to improve cardiovascular health and minimize the risk of complications related to obesity.
  • Eat more plant based foods like vegetables, fruits and whole grains.
  • Reduce intake of foods containing high fat such as dairy, oil and red meat.
  • Exercise for at least 30 minutes 5 days a week.
  • Aim for weight loss and maintain healthy weight.
  • Quit smoking.
  • Control blood sugar and blood pressure.
Here are the steps to Dry Mouth (xerostomia) caused by medication:
  • Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
  • Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
  • Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
  • Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
  • Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Here are the 7 step-by-step strategies to manage the side effect of "inability to sleep" caused by medication usage:
  • Prepare for a restful night's sleep: Develop a calming pre-sleep routine, like reading or meditation, to help your body relax and prepare for sleep.
  • Create a sleep-conducive Environment: Make bedroom a sleep haven by ensuring it is quiet, dark and calm.
  • Follow a Sleep Schedule: Go to bed and get up at the same time every day to help regulate your body's internal clock and increase sleep quality.
  • Try relaxing techniques like deep breathing, mindfulness meditation and any others.
  • Limit stimulating activities before bedtime: Avoid stimulating activities before bedtime to improve sleep quality.
  • Monitor Progress: Keep track of your sleep patterns to identify areas for improvement.
  • Consult a doctor if needed: If these steps don't improve your sleep, consult a doctor for further guidance and therapy.
  • Discuss with your doctor if you suspect a medicine is causing hyperprolactinemia. Your doctor may reduce the dose or switch to an alternative medicine with low impact on prolactin levels.
  • Assess the severity of your symptoms related to high prolactin levels, like sexual dysfunction in men and menstrual irregularities in women for treatment choices.
  • Regular blood tests are recommended to monitor prolactin levels to assess treatment effectiveness.

What if I have taken an overdose of Tolaz LA 405mg/vial Convenience Kit

Since Tolaz LA 405mg/vial Convenience Kit is given in a controlled medical setting by a healthcare professional, an overdose is not likely to occur. If you think there has been an overdose or if you are experiencing any adverse events, get medical care right away. In a medical setting, an overdose would be treated quickly. Adverse effects of Tolaz LA 405mg/vial Convenience Kit may cause agitation, aggressive behaviour, Confusion, dizziness, disorientation, difficulty walking, slurred speech, slowed or uncontrollable movements, muscle stiffness, weakness, seizures, fast heartbeat, drowsiness, and coma (loss of consciousness for a period of time).

Drug Warnings

  • Tolaz LA 405mg/vial Convenience Kit is not recommended for use in patients with Dementia-Related Psychosis.
  • Brief your medical history to the doctor if you have any allergic reactions, liver or kidney diseases, Alzheimer's disease, dementia, heart problems, breathing problems, high cholesterol, glaucoma, diabetes, bowel problems, sleep apnea, low white blood cell count, breast cancer, enlarged prostate, or fits before starting Tolaz LA 405mg/vial Convenience Kit.
  • Please inform your doctor if you are pregnant or planning to conceive before starting this medicine.
  • Tolaz LA 405mg/vial Convenience Kit is not recommended during breastfeeding.
  • Avoid consuming alcohol as it might lead to increased side effects like dizziness and drowsiness.
  • Avoid driving or operating machinery as Tolaz LA 405mg/vial Convenience Kit may decrease your mental alertness, making you feel dizzy or drowsy.
  • Tolaz LA 405mg/vial Convenience Kit is not recommended for people below 18 years of age, as safety and effectiveness have not been established.

Drug-Drug Interactions

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OlanzapinePotassium chloride
Critical
OlanzapineRopinirole
Critical

Drug-Drug Interactions

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OlanzapinePotassium chloride
Critical
How does the drug interact with Tolaz LA 405mg/vial Convenience Kit:
Taking Tolaz LA 405mg/vial Convenience Kit with Potassium chloride can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Co-administration of Tolaz LA 405mg/vial Convenience Kit and Potassium chloride is not recommended as it leads to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like severe abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, and/or black, tarry stools, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
OlanzapineRopinirole
Critical
How does the drug interact with Tolaz LA 405mg/vial Convenience Kit:
When Ropinirole is taken with Tolaz LA 405mg/vial Convenience Kit, it may reduce the effectiveness of ropinirole.

How to manage the interaction:
Taking Ropinirole with Tolaz LA 405mg/vial Convenience Kit is not recommended as it can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as drowsiness, low blood pressure, dizziness, and lightheadedness. Do not stop using any medications without consulting doctor.
OlanzapinePotassium citrate
Critical
How does the drug interact with Tolaz LA 405mg/vial Convenience Kit:
Taking Tolaz LA 405mg/vial Convenience Kit with Potassium citrate can increase the irritant effects of potassium on your stomach and upper intestine.

How to manage the interaction:
Co-administration of Tolaz LA 405mg/vial Convenience Kit and Potassium citrate is not recommended as it leads to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like severe abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, and/or black, tarry stools, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
OlanzapinePramipexole
Critical
How does the drug interact with Tolaz LA 405mg/vial Convenience Kit:
Taking Tolaz LA 405mg/vial Convenience Kit with Pramipexole can increase the risk and severity of side effects and reduce the effectiveness of Pramipexole.

How to manage the interaction:
Co-administration of Tolaz LA 405mg/vial Convenience Kit and Pramipexole is not recommended as it leads to an interaction, it can be taken if advised by a doctor. If you experience any symptoms such as drowsiness, dizziness, and lightheadedness, contact a doctor immediately. Avoid driving or operating dangerous machinery, and be careful while getting up from a sitting or lying position. Do not discontinue any medications without consulting a doctor.
OlanzapineHydrocodone
Severe
How does the drug interact with Tolaz LA 405mg/vial Convenience Kit:
Combining Tolaz LA 405mg/vial Convenience Kit with Hydrocodone can cause central nervous system depression such as Tolaz LA 405mg/vial Convenience Kit can lead to serious side effects including respiratory distress, intestinal obstruction, fecal impaction.

How to manage the interaction:
Although taking Tolaz LA 405mg/vial Convenience Kit and Hydrocodone together can lead to an interaction, it can be taken if your doctor has suggested it. If you experience any symptoms like feeling tired, having trouble breathing, feeling dizzy or drowsy, difficulty focusing, taking pain or cough medications, constipation, blockage in your intestines, difficulty passing stool, hard or dry stool, less frequent bowel movements, stomach problems, feeling sick, feeling bloated, having stomach pain, or swelling contact the doctor immediately. you should avoid driving or operating hazardous machinery until you know how they affect you and do not discontinue any medications without consulting your doctor.
OlanzapineDezocine
Severe
How does the drug interact with Tolaz LA 405mg/vial Convenience Kit:
Combining Tolaz LA 405mg/vial Convenience Kit with Dezocine can increase the risk of central nervous system depression and respiratory distress.

How to manage the interaction:
Although taking Tolaz LA 405mg/vial Convenience Kit and Dezocine together can lead to an interaction, it can be taken if your doctor has suggested it. If you experience any symptoms like feeling tired, having trouble breathing, feeling dizzy or drowsy, difficulty focusing, constipation, difficulty passing stool, hard or dry stool, less frequent bowel movements, stomach problems, feeling sick, feeling bloated, having stomach pain, or swelling contact the doctor immediately. You should avoid driving or operating hazardous machinery until you know how they affect you, and do not discontinue any medications without consulting your doctor.
OlanzapinePentazocine
Severe
How does the drug interact with Tolaz LA 405mg/vial Convenience Kit:
Combining Tolaz LA 405mg/vial Convenience Kit with Pentazocine can cause central nervous system depression such as Tolaz LA 405mg/vial Convenience Kit can lead to serious side effects including respiratory distress, intestinal obstruction, fecal impaction.

How to manage the interaction:
Although taking Tolaz LA 405mg/vial Convenience Kit and Pentazocine together can lead to an interaction, it can be taken if your doctor has suggested it. If you experience any symptoms like feeling tired, having trouble breathing, feeling dizzy or drowsy, difficulty focusing, taking pain or cough medications, constipation, blockage in your intestines, difficulty passing stool, hard or dry stool, less frequent bowel movements, stomach problems, feeling sick, feeling bloated, having stomach pain, or swelling contact the doctor immediately. you should avoid driving or operating hazardous machinery until you know how they affect you and do not discontinue any medications without consulting your doctor.
OlanzapineCiprofloxacin
Severe
How does the drug interact with Tolaz LA 405mg/vial Convenience Kit:
Coadministration of Tolaz LA 405mg/vial Convenience Kit and ciprofloxacin can increase blood levels and the effects of Tolaz LA 405mg/vial Convenience Kit, which may lead to side effects.

How to manage the interaction:
Although taking ciprofloxacin and Tolaz LA 405mg/vial Convenience Kit together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, if you experience difficulty swallowing, low blood pressure, irregular heart rhythm, and seizures(fits) consult the doctor immediately. Do not stop using any medications without talking to a doctor.
OlanzapineMidazolam
Severe
How does the drug interact with Tolaz LA 405mg/vial Convenience Kit:
When used together, Midazolam and Tolaz LA 405mg/vial Convenience Kit can cause low blood pressure, shallow breathing, weak pulse, muscle weakness, drowsiness, dizziness and slurred speech.

How to manage the interaction:
Combining of Tolaz LA 405mg/vial Convenience Kit and Midazolam can lead to an interaction, it can be taken if your doctor has suggested it. If you experience any symptoms consult the doctor immediately. Avoid activities requiring mental alertness until you know how these medications will affect you and do not discontinue any medications without consulting a doctor.
OlanzapineNalbuphine
Severe
How does the drug interact with Tolaz LA 405mg/vial Convenience Kit:
Combining Tolaz LA 405mg/vial Convenience Kit with Nalbuphine can cause central nervous system depression such as Tolaz LA 405mg/vial Convenience Kit can lead to serious side effects including respiratory distress, intestinal obstruction, fecal impaction.

How to manage the interaction:
Although taking Tolaz LA 405mg/vial Convenience Kit and Nalbuphine together can lead to an interaction, it can be taken if your doctor has suggested it. If you experience any symptoms like feeling tired, having trouble breathing, feeling dizzy or drowsy, difficulty focusing, taking pain or cough medications, constipation, blockage in your intestines, difficulty passing stool, hard or dry stool, less frequent bowel movements, stomach problems, feeling sick, feeling bloated, having stomach pain, or swelling contact the doctor immediately. you should avoid driving or operating hazardous machinery until you know how they affect you and do not discontinue any medications without consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Diet:

  • Maintain a healthy weight by following a balanced diet.
  • Include fruits and vegetables rich in antioxidants.
  • Eat nutritious foods that support brain function.
  • Limit foods high in cholesterol and saturated fats.
  • Minimise intake of sugar, salt, and processed foods.

Physical Activity:

  • Exercise regularly to support brain health and reduce cognitive decline.

Habits:

  • Avoid smoking and alcohol consumption.
  • Drink plenty of water to stay hydrated.

Stress Management & Lifestyle:

  • Manage stress through meditation or yoga.
  • Follow a healthy daily routine to support overall health and protect the brain.

Habit Forming

No

Therapeutic Class

[ANTIPSYCHOTICS]

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Alcohol

Unsafe

Avoid alcohol consumption while taking Tolaz LA 405mg/vial Convenience Kit as it may cause increased dizziness and drowsiness.

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Pregnancy

Caution

Tolaz LA 405mg/vial Convenience Kit is a pregnancy category C drug. Using antipsychotic drugs during the third trimester of pregnancy may cause muscle problems in newborn babies. There are no adequate, well-controlled studies in pregnant women. Please inform your doctor before taking Tolaz LA 405mg/vial Convenience Kit if you are pregnant or planning pregnancy. Your doctor will weigh the potential risks and benefits before prescribing Tolaz LA 405mg/vial Convenience Kit.

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Breast Feeding

Unsafe

Tolaz LA 405mg/vial Convenience Kit is excreted into the breast milk. Hence it is not recommended for a nursing mother. Please inform your doctor before using Tolaz LA 405mg/vial Convenience Kit if you are a breastfeeding mother.

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Driving

Unsafe

Tolaz LA 405mg/vial Convenience Kit may make you feel dizzy or drowsy. Do not drive or operate machinery if you are not mentally alert or experience any symptoms that affect your ability to concentrate.

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Liver

Caution

Tolaz LA 405mg/vial Convenience Kit should not be used in case of Hepatitis (including hepatocellular, cholestatic or mixed liver injury). If you have a history of liver disease, inform your doctor before receiving Tolaz LA 405mg/vial Convenience Kit. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Caution

If you have a history of kidney disease, inform your doctor before receiving Tolaz LA 405mg/vial Convenience Kit. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Unsafe

Tolaz LA 405mg/vial Convenience Kit is not indicated for use in treating children and adolescents below 18 years of age. Please seek medical advice.

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Heart

Caution

Inform your doctor before receiving the Tolaz LA 405mg/vial Convenience Kit if you have heart disease. Your doctor will prescribe only if the benefits outweigh the risks.

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Geriatrics

Caution

Tolaz LA 405mg/vial Convenience Kit should be used with caution in elderly patients. Please consult your doctor before use.

FAQs

Tolaz LA 405mg/vial Convenience Kit is used to treat Schizophrenia and bipolar I disorder.

Tolaz LA 405mg/vial Convenience Kit contains Olanzapine, an antipsychotic that balances the chemical messengers in the brain, improving mood, behaviour and thoughts.

Tolaz LA 405mg/vial Convenience Kit should be used with caution in the medical history of allergic reactions, liver or kidney diseases, heart problems, Alzheimer's disease, high cholesterol, glaucoma, diabetes, stomach/intestinal problems, breathing problems during sleep (sleep apnea), low white blood cell count, breast cancer, enlarged prostate, or fits. Please let your doctor know if you have any other medical history before starting the treatment with Tolaz LA 405mg/vial Convenience Kit.

Tolaz LA 405mg/vial Convenience Kit may make you sweat less and can likely cause a heart stroke. Hence, limiting activities that cause overheating, like an exercise in hot weather or using hot tubs, is advised. Drink plenty of fluids and dress lightly.

Tolaz LA 405mg/vial Convenience Kit may cause dizziness. It is advised to avoid getting up too fast from a sitting or lying position that can make you feel dizzy.

$nam can cause side effects like orthostatic hypotension (sudden lowering in blood pressure leading to dizziness on standing). If you experience this, do not try to stand up suddenly or start walking; instead, lie down and get up slowly only when you feel better. This medicine should be used cautiously in people with cardiovascular and cerebrovascular diseases. Patients taking Tolaz LA 405mg/vial Convenience Kit are advised to regularly monitor their blood pressure to prevent adverse events. It is also advised to be aware of a condition called tardive dyskinesia (uncontrolled movements of the face, lips, mouth, tongue, arms or legs) that may rarely occur while using this medicine.

Country of origin

India

Manufacturer/Marketer address

Off. Ashram Road, Ahmedabad - 380 009., Gujarat, India
Other Info - TOL0116

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