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Tolneed 15 Tablet 4's is used to treat hyponatremia (low levels of sodium) in patients with heart failure, liver disease and hormonal imbalances such as Syndrome of Inappropriate Antidiuretic Hormone (SIADH). Additionally, Tolneed 15 Tablet 4's is also used to treat autosomal dominant polycystic kidney disease (ADPKD).
Tolneed 15 Tablet 4's contains ‘tolvaptan’ that works by blocking the effect of vasopressin, resulting in decreased water reabsorption, a net increase in free water excretion (aquaresis) and an increase in serum sodium concentrations.
In some cases, you may experience certain common side effects such as dizziness, headache, dry mouth, fatigue, diarrhoea, thirst and increased urge to urinate. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
You can take Tolneed 15 Tablet 4's with food or as advised by your doctor. It should be swallowed whole with a glass of water. Do not chew, bite, or break it. You are advised to take Tolneed 15 Tablet 4's as long as your doctor has prescribed it for you, depending on your medical condition.
Do not take Tolneed 15 Tablet 4's if you are allergic to it or any of its components. Avoid taking Tolneed 15 Tablet 4's if you are pregnant as it may cause foetal harm. Consult your doctor before taking Tolneed 15 Tablet 4's if you are breastfeeding. Tolneed 15 Tablet 4's is not recommended for children below 18 years as the efficacy and safety have not been established.
Tolneed 15 Tablet 4's used in the treatment of hyponatremia (low sodium levels) and autosomal dominant polycystic kidney disease (ADPKD). The detailed uses of Tolneed 15 Tablet 4's are as follows:
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Avoid consuming alcohol while taking Tolneed 15 Tablet 4's as it may cause increased dizziness.
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Tolneed 15 Tablet 4's belongs to pregnancy category C. Tolneed 15 Tablet 4's is not recommended for use in pregnant women as it may cause foetal harm. Women of childbearing age must use effective contraception while taking Tolneed 15 Tablet 4's.
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Tolneed 15 Tablet 4's is not recommended for use in breastfeeding women. Consult your doctor if you are breastfeeding; your doctor will decide whether Tolneed 15 Tablet 4's can be taken by breastfeeding mothers or not.
Caution
Tolneed 15 Tablet 4's may cause dizziness, weakness and tiredness. Do not drive or operate heavy machinery if you feel dizzy.
Caution
Tolneed 15 Tablet 4's should be used with caution in patients with liver impairment/liver disease. Please consult your doctor if you have liver problems or any concerns regarding this.
Caution
Tolneed 15 Tablet 4's should be used with caution in patients with kidney disease. Please consult your doctor if you have kidney problems or any concerns regarding this.
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Tolneed 15 Tablet 4's is not recommended for children below 18 years as efficacy and safety have not been established.
Consult your doctor
Please inform your doctor if you have a history of heart disease before using Tolneed 15 Tablet 4's. Your doctor will prescribe it only if the benefits outweigh the risks.
Caution
Tolneed 15 Tablet 4's can be given in elderly patients with extreme caution, if prescribed by the physician.
Have a query?
The time required for Tolneed 15 Tablet 4's to start to work: Tolneed 15 Tablet 4's ideally shows its action within 2 to 4 hours after administration.
The time for which the effects of Tolneed 15 Tablet 4's last: The effect of Tolneed 15 Tablet 4's lasts for 12 hours.
Drug-Drug Interaction: Inform the doctor if you are taking antibiotics (clarithromycin, telithromycin, sulfamethoxazole, trimethoprim), anti-fungal (ketoconazole, itraconazole), anti-HIV (ritonavir, indinavir, nelfinavir, saquinavir), antidepressant (nefazodone), aldosterone receptor antagonist (spironolactone), angiotensin receptor inhibitor (valsartan, sacubitril), blood thinner (heparin).
Drug-Food Interaction: Avoid consuming grapefruit juice and St. John’s wort (herbal supplement used to treat depression) while taking Tolneed 15 Tablet 4's.
Drug-Disease Interaction: Inform the doctor if you have liver disease, difficulty in urination, diabetes, high levels of uric acid or kidney disease.
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Tolneed 15 Tablet 4's is used to treat hyponatremia (low levels of sodium) in patients with heart failure, liver disease and hormonal imbalances such as Syndrome of Inappropriate Antidiuretic Hormone (SIADH). Additionally, Tolneed 15 Tablet 4's is also used to treat autosomal dominant polycystic kidney disease (ADPKD).
Tolneed 15 Tablet 4's works by blocking the effect of vasopressin, a hormone which is involved in the formation of cysts in ADPKD patients. By blocking the effect of vasopressin, Tolneed 15 Tablet 4's slows down the development of cysts in the kidneys, reduces the symptoms of the disease, and increases urine production. Thereby increases serum sodium concentrations.
Dry mouth could be a side-effect of Tolneed 15 Tablet 4's. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly and chewing sugar-free gum/candy might help in stimulating saliva and thereby prevents drying of the mouth.
Diarrhoea could be a side-effect of Tolneed 15 Tablet 4's. Drink plenty of fluid to prevent dehydration if you experience diarrhoea. Consult your doctor if you have severe diarrhoea or if you find blood in stools.
Tolneed 15 Tablet 4's may cause the liver to not work properly. Consult your doctor immediately if you experience nausea, vomiting, fever, loss of appetite, abdominal pain, tiredness, dark urine, jaundice, itching and flu-like symptoms.
Tolneed 15 Tablet 4's may cause water loss due to increased urine production. This might result in side-effects such as thirst, dry mouth and kidney problems. To prevent this, drink plenty of water regularly. Drink 1-2 glasses of water before going to bed even though you are not thirsty. Special care must be taken in patients with diseases that might reduce fluid intake.
Consult your doctor before taking Tolneed 15 Tablet 4's if you are diabetic as Tolneed 15 Tablet 4's might increase the blood sugar levels. Regular monitoring of blood glucose levels while taking Tolneed 15 Tablet 4's is advised.
You are advised to take Tolneed 15 Tablet 4's for the duration prescribed by the doctor. Tolneed 15 Tablet 4's should not be taken for more than 30 days.
Tolneed 15 Tablet 4's might increase the blood sugar levels. Consult the doctor if you are diabetic.
Do not take Tolneed 15 Tablet 4's if you are allergic to any of its components, if you have raised liver enzymes in the blood, very low blood volume, if there is no urine production, or if you cannot tell that you are thirsty.
Avoid consuming grapefruit or its juice while taking Tolneed 15 Tablet 4's as it might increase the effects of the medicine in the body.
Do not exceed the prescribed dose as it might cause an overdose. Taking an excess of Tolneed 15 Tablet 4's may cause excessive thirst, dizziness, excessive urination, or fainting. Consult the doctor if you experience these symptoms.
Tolneed 15 Tablet 4's is not recommended for patients with severe kidney disease. It should be used with caution in patients with mild to moderate kidney problems.
If you miss a dose of Tolneed 15 Tablet 4's take it as soon as you remember, However, if it is almost time for the scheduled dose, skip the missed dose and take the next dose at the scheduled time.
Tolneed 15 Tablet 4's is not recommended for use during pregnancy and breastfeeding.
Common side effects are dizziness, headache, dry mouth, fatigue, diarrhoea, thirst and increased urge to urinate. Talk to your doctor if you experience these side effects persistently.
Store Tolneed 15 Tablet 4's at room temperature, in a dry place. Keep out of sight and reach of children.
Treatment with Tolneed 15 Tablet 4's should be started and re-started in a hospital or in the presence of a healthcare professional to monitor the sodium levels in your blood closely. Too rapid correction of hyponatremia (low sodium levels) may cause osmotic demyelination syndrome (serious nerve damage). Consult the doctor if you notice symptoms of osmotic demyelination syndrome such as difficulty speaking, feeling that food or drinks are getting stuck in your throat, difficulty swallowing, mood changes, drowsiness, confusion, body movements that are difficult to control, weakness of the arms or legs, or seizures.
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