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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
TOLPERITAS-DSR TABLETS is used to reduce and relieve pain due to the muscle spasms (excessive tension in the muscles). It contains Diclofenac and Tolperisone, which work on the brain and spinal cord centres to relieve muscle stiffness or spasm and relieve pain and improve muscle's movement. Also, it reduces mild to moderate pain and inflammation. It may cause side effects such as nausea, diarrhoea, vomiting, heartburn, weakness, stomach pain/epigastric pain, sleepiness, dizziness, and appetite loss. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About TOLPERITAS-DSR TABLETS

TOLPERITAS-DSR TABLETS belongs to a class of medications called Non-steroidal anti-inflammatory drugs (NSAIDs) or pain killer. TOLPERITAS-DSR TABLETS is used to reduce and relieve pain due to the muscle spasms (excessive tension in the muscles). Muscle spasm is the sudden involuntary contractions of the muscle, which can be painful and uncomfortable. When the nerve impulses that control the muscle movements are damaged or interrupted, it could lead to muscle spasms.

TOLPERITAS-DSR TABLETS is a combination of two drugs, namely: Diclofenac and Tolperisone. Diclofenac is a pain killer (NSAIDs) while Tolperisone is a skeletal muscle relaxant. Diclofenac works by blocking the effect of a chemical messenger in your body, known as cyclo-oxygenase (COX) enzymes that make another chemical 'prostaglandins' (PG). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking COX enzyme's effect, lesser PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site. On the other hand, Tolperisone works on the brain and spinal cord centres to relieve muscle stiffness or spasm and relieve pain and improve muscle's movement.

Take TOLPERITAS-DSR TABLETS as prescribed by your doctor. You are advised to take TOLPERITAS-DSR TABLETS for as long as your doctor has prescribed it for you depending on your medical conditions. You may experience nausea, diarrhoea, vomiting, heartburn, weakness, stomach pain/epigastric pain, sleepiness, dizziness, and appetite loss. Most of these side effects of TOLPERITAS-DSR TABLETS do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

TOLPERITAS-DSR TABLETS can increase your risk of fatal heart attack or stroke. So, if you have had any recent heart surgery, do not use TOLPERITAS-DSR TABLETS. TOLPERITAS-DSR TABLETS increases the chances of stomach ulcers and bleeding.  Before taking this TOLPERITAS-DSR TABLETS, inform your doctor if you have any allergies, myasthenia gravis (weakness in muscles), asthma, and hay fever. To treat your condition effectually, continue taking TOLPERITAS-DSR TABLETS for as long as your doctor has prescribed. Do not take TOLPERITAS-DSR TABLETS if you are pregnant or breastfeeding unless prescribed. TOLPERITAS-DSR TABLETS causes drowsiness and dizziness, so drive with caution. TOLPERITAS-DSR TABLETS should not be given to children as safety and efficacy have not been established. Avoid consuming alcohol along with TOLPERITAS-DSR TABLETS as it could lead to increased drowsiness and dizziness, it might also increase the risk of stomach bleeding. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Uses of TOLPERITAS-DSR TABLETS

TOLPERITAS-DSR TABLETS is used in the treatment of muscle pain, spasms, and inflammation. The detailed uses of TOLPERITAS-DSR TABLETS are as follows:<br/>• Pain Relief: TOLPERITAS-DSR TABLETS provides effective relief from various painful conditions, including back pain, neck pain, joint and bone disorders, and post-operative pain, enhancing daily functioning and quality of life.<br/>• Muscle Spasms relief: TOLPERITAS-DSR TABLETS helps to relax muscles, alleviate spasms and tension, and improve mobility, allowing for better movement and reduced discomfort.<br/>• Anti-inflammatory Effects: TOLPERITAS-DSR TABLETS reduces inflammation and swelling, helping to alleviate pain and discomfort in conditions like arthritis, sprains, and strains.<br/>

Directions for Use

• Take TOLPERITAS-DSR TABLETS with food to avoid stomach upset or as advised by a doctor.• Follow your doctor's instructions on the dosage and timing of this medication, to ensure the safety.• Swallow the medicine as a whole with glass of water.• Do not crush, break, or chew it.

Medicinal Benefits

TOLPERITAS-DSR TABLETS belongs to a class of medications called Non-steroidal anti-inflammatory drugs (NSAIDs) or pain killers. TOLPERITAS-DSR TABLETS is a combination of two drugs, namely: Diclofenac and Tolperisone. Diclofenac is a pain killer (NSAIDs) while Tolperisone is a skeletal muscle relaxant. Diclofenac works by blocking the effect of a chemical messenger in your body, known as cyclo-oxygenase (COX) enzymes that make another chemical 'prostaglandins' (PG). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking COX enzyme's effects, lesser PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site. On the other hand, Tolperisone works on the brain and spinal cord centres to relieve muscle stiffness or spasm and relieve pain and improve muscle's movement. Altogether TOLPERITAS-DSR TABLETS relieves pain and relaxes the muscles.

How TOLPERITAS-DSR TABLETS Works

TOLPERITAS-DSR TABLETS is a combination of two drugs, namely: Diclofenac and Tolperisone. Diclofenac is a pain killer (NSAIDs) while Tolperisone is a skeletal muscle relaxant. Diclofenac works by blocking the effect of a chemical messenger in your body, known as cyclo-oxygenase (COX) enzymes that make another chemical 'prostaglandins' (PG). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking COX enzyme's effect, lesser PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site. On the other hand, Tolperisone works on the brain and spinal cord centres to relieve muscle stiffness or spasm and relieve pain and improve muscle's movement.

Storage

Keep this medicine out of the sight and reach of children.

What if I have taken an overdose of TOLPERITAS-DSR TABLETS

Do not take more than the prescribed dose of TOLPERITAS-DSR TABLETS as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

TOLPERITAS-DSR TABLETS can increase your risk of fatal heart attack or stroke. So, if you have had any recent heart surgery, do not use TOLPERITAS-DSR TABLETS. Do not take TOLPERITAS-DSR TABLETS if you are allergic to TOLPERITAS-DSR TABLETS, have severe heart failure, have suffered bleeding problems such as bleeding from stomach or bowels while taking any pain killers or you have liver or kidney problems. Inform your doctor before taking TOLPERITAS-DSR TABLETS if you have or had high blood pressure, heart problems, high cholesterol, diabetes, asthma, liver and kidney problems. Do not take TOLPERITAS-DSR TABLETS if you are pregnant or breastfeeding unless prescribed. TOLPERITAS-DSR TABLETS causes drowsiness and dizziness, so drive only if you are alert. TOLPERITAS-DSR TABLETS should not be given to children as the safety have not been established. Avoid consuming alcohol and TOLPERITAS-DSR TABLETS as it could lead to increased drowsiness and increase the risk of stomach bleeding. Stop taking TOLPERITAS-DSR TABLETS and consult your doctor immediately if you have stomach pain or any signs of bleeding in intestine or stomach such as blood in stools. Do not take any other NSAID's for pain relief along with TOLPERITAS-DSR TABLETS unless prescribed. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Drug-Drug Interactions

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DiclofenacLomitapide
Severe

Drug-Drug Interactions

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How does the drug interact with Tolperitas-DSR Tablet:
Co-administration of Tolperitas-DSR Tablet with Meloxicam can increase the risk or severity of gastrointestinal side effects.

How to manage the interaction:
Taking Meloxicam with Tolperitas-DSR Tablet is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop any medication without doctor's advise.
DiclofenacLomitapide
Severe
How does the drug interact with Tolperitas-DSR Tablet:
Taking Tolperitas-DSR Tablet with Lomitapide will have an additive effect and may cause liver problems.

How to manage the interaction:
There may be a possible interaction between Tolperitas-DSR Tablet and Lomitapide, but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you have fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark colored urine, light colored stools, and/or yellowing of the skin or eyes. Do not stop using any medications without a doctor's advice.
How does the drug interact with Tolperitas-DSR Tablet:
Taking amiloride with Tolperitas-DSR Tablet can increase the risk of kidney problems, hyperkalemia(high potassium levels in blood), and high blood pressure.

How to manage the interaction:
There could be a possible interaction between Tolperitas-DSR Tablet and amiloride, but they can be taken together if your doctor has prescribed them. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Tolperitas-DSR Tablet:
Co-administration use of Tolperitas-DSR Tablet with Flubiprofen may increase the risk of stomach bleeding and ulcers.

How to manage the interaction:
There is a possibility of interaction between Tolperitas-DSR Tablet and Flubiprofen but they can be taken together if your doctor has prescribed them. Consult your doctor immediately if you experience any symptoms like Nausea, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, burning in stomach, acidity, severe headache and weakness. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Tolperitas-DSR Tablet:
Co-administration of Tolperitas-DSR Tablet with tenofovir disoproxil may increase the risk of developing kidney problems.

How to manage the interaction:
There may be a possible interaction between Tolperitas-DSR Tablet and Tenofovir disoproxil but they can be taken together if your doctor has prescribed them. However consult your doctor immediately if you experience symptoms such as such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without first talking to your doctor.
DiclofenacSulindac
Severe
How does the drug interact with Tolperitas-DSR Tablet:
Co-administration of Tolperitas-DSR Tablet and sulindac can increase the risk of side effects.

How to manage the interaction:
Although there is a interaction between Tolperitas-DSR Tablet and sulindac, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Tolperitas-DSR Tablet:
Co-administration of Tolperitas-DSR Tablet with Sirolimus may increase the risk or severity of kidney problems.

How to manage the interaction:
Co-administration of Tolperitas-DSR Tablet and Sirolimus can lead to an interaction, but it can be taken if advised by a doctor. However, consult a doctor if you experience any symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Tolperitas-DSR Tablet:
Co-administration use of Tolperitas-DSR Tablet with Dalteparin may increase the risk of bleeding complications.

How to manage the interaction:
Although taking Dalteparin with Tolperitas-DSR Tablet may possibly lead to an interaction, they can be taken if a doctor prescribes it. Consult a doctor if you have any symptoms including dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that resembles coffee grounds, severe headache, and weakness. Without consulting a doctor, never stop taking any medication.
How does the drug interact with Tolperitas-DSR Tablet:
Coadministration of Tolperitas-DSR Tablet with fondaparinux may increase the risk of bleeding.

How to manage the interaction:
There may be a possible interaction between Tolperitas-DSR Tablet and Fondaparinux when taken together, but they can be taken together if your doctor has prescribed them. However, if you experience bleeding, severe back pain, dizziness, black or red stools, severe headache, weakness, and vomiting contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Tolperitas-DSR Tablet:
Coadministration of Tolperitas-DSR Tablet and Naproxen can increase the risk or severity of side effects.

How to manage the interaction:
Taking Tolperitas-DSR Tablet and Naproxen together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact your doctor immediately. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Exercising regularly helps in muscle stretching so that they are less likely to spasm, tear and sprain. Mild exercises such as jogging and walking are helpful for muscle stretching.
  • Massages can also be helpful.
  • Avoid freezing and hot temperatures.
  • Avoid wearing tight-fitting clothes, instead, wear loose garments.
  • Rest well, get plenty of sleep.
  • To avoid developing pressure sores, change your position at least every two hours.
  • Hot or cold therapy can help treat muscle spasms. Apply an ice-pack or hot-pack on the muscle for 15-20minutes.
  • Stay hydrated, drink plenty of water.

Habit Forming

No

Therapeutic Class

ANALGESICS
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Alcohol

Unsafe

Avoid consumption of alcohol while taking TOLPERITAS-DSR TABLETS as it may increase dizziness. It can also increase the risk of stomach bleeding.

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Pregnancy

Caution

Avoid taking TOLPERITAS-DSR TABLETS if you are pregnant unless prescribed by a doctor. Please consult your doctor if you have any concerns regarding this, your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Unsafe

TOLPERITAS-DSR TABLETS must not be used during breastfeeding.

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Driving

Caution

TOLPERITAS-DSR TABLETS may cause sleepiness or dizziness. Do not drive or do anything needing concentration until you know how it affects you.

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Liver

Unsafe

Those who have severe liver problems should not take this TOLPERITAS-DSR TABLETS because TOLPERITAS-DSR TABLETS contains Tolperisone, which causes the most dangerous adverse in patients with liver disease.

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Kidney

Unsafe

Those who have severe kidney problems should not take this TOLPERITAS-DSR TABLETS because TOLPERITAS-DSR TABLETS contains Tolperisone, which causes the most dangerous adverse in patients with kidney disease.

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Children

Unsafe

TOLPERITAS-DSR TABLETS should not be given to children as the safety and effectiveness were not established.

Have a query?

FAQs

TOLPERITAS-DSR TABLETS is used to reduce and relieve pain due to the muscle spasms (excessive tension in the muscles).

TOLPERITAS-DSR TABLETS is a combination of two drugs: Diclofenac (Nonsteroidal Anti-Inflammatory Drug) and metaxalone (skeletal muscle relaxant). Diclofenac works by blocking the action of certain chemical messengers that cause pain. Tolperisone works on the spinal cord and centres in the brain to relieve contraction or muscle stiffness without decreasing strength.

TOLPERITAS-DSR TABLETS may impair mental and/or physical abilities required for the performance of heavy tasks like operating machinery or driving a motor vehicle, especially when used with alcohol.

Do not take TOLPERITAS-DSR TABLETS for longer durations as it might increase the risk of heart problems, liver problems and stomach bleeding/ulcer. Please consult a doctor before its use.

There are no recognized reports of any patient getting addicted to TOLPERITAS-DSR TABLETS.

If you are suffering from muscle pain due to overuse or muscle injury, you should take rest. Taking rest will help you to prevent any further injury and help you improve effectively. Make sure that you take enough sleep and try to decrease stress. Applying an ice pack to the altered area may help in reducing inflammation and pain. If your muscle pain is due to some other illness, follow the guidance of your doctor.

Take a missed dose as soon as you remember it. If it is close to the time for your next dose, skip the missed dose and go back to your regular time. Do not take 2 doses at the same time or extra doses.

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - TOL0181

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