apollo

Online Doctor Consultation & Medicines

Hello,

Select your location

0

Special offers

  1. Home

  2. Tolsama 15 Tablet 4's

Tolsama 15 Tablet 4's, Pack of 4 TABLETS
Tolsama 15 Tablet 4's, Pack of 4 TABLETS

Tolsama 15 Tablet 4's

Manufacturer/Marketer

Msn Laboratories Ltd

Composition

TOLVAPTAN-15MG

Consume Type

ORAL

In Stock

Prescription Required
Product Details

About Tolsama 15 Tablet 4's

Tolsama 15 Tablet 4's belongs to a group of medicines called vasopressin V2 receptor antagonist used to treat hyponatremia (low levels of sodium) in patients with heart failure, liver disease and hormonal imbalances such as Syndrome of Inappropriate Antidiuretic Hormone (SIADH). Additionally, Tolsama 15 Tablet 4's is also used to treat autosomal dominant polycystic kidney disease (ADPKD).
 
Tolsama 15 Tablet 4's contains ‘tolvaptan’ that works by blocking the effect of vasopressin, resulting in decreased water reabsorption, a net increase in free water excretion (aquaresis) and an increase in serum sodium concentrations. This decrease in free water is not associated with an increased excretion of sodium or potassium ions, the increase in serum sodium concentration is solely a result of  increased urine production
 
You are advised to take Tolsama 15 Tablet 4's for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, you may experience certain common side-effects such as dizziness, headache, dry mouth, fatigue, diarrhoea, thirst and increased urge to urinate. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.
 
Do not take Tolsama 15 Tablet 4's if you are pregnant as it may cause foetal harm. Consult your doctor before taking Tolsama 15 Tablet 4's if you are breastfeeding. Tolsama 15 Tablet 4's is not recommended for children below 18 years as the efficacy and safety have not been established. Tolsama 15 Tablet 4's may cause dizziness, so drive with caution. Avoid consuming alcohol as it might cause increased dizziness. Inform your doctor about all the medicines you are taking and about your health condition to rule out any unpleasant side-effects.

Uses of Tolsama 15 Tablet 4's

Hyponatremia (low sodium levels) and autosomal dominant polycystic kidney disease (ADPKD).

Medicinal Benefits

Tolsama 15 Tablet 4's belongs to a group of medicines called vasopressin V2 receptor antagonist. Tolsama 15 Tablet 4's is used to treat hyponatremia (low levels of sodium) in patients with heart failure, liver disease and hormonal imbalances such as Syndrome of Inappropriate Antidiuretic Hormone (SIADH). Besides this, Tolsama 15 Tablet 4's is also used to treat autosomal dominant polycystic kidney disease (ADPKD). Tolsama 15 Tablet 4's works by blocking the effect of vasopressin, a hormone which is involved in the formation of cysts in ADPKD patients. By blocking the effect of vasopressin, Tolsama 15 Tablet 4's slows down the development of cysts in kidneys and reduces the symptoms of the disease. Tolsama 15 Tablet 4's antagonises the effect of vasopressin, this results in an increase in free water clearance and decreases urine osmolality due to increased urinary excretion, thereby increases serum sodium concentrations.

Directions for Use

Swallow Tolsama 15 Tablet 4's as a whole with a glass of water, do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Tolsama 15 Tablet 4's

  • Dizziness
  • Headache
  • Dry mouth
  • Fatigue
  • Weakness
  • Diarrhoea
  • Thirst
  • Increased urge to urinate

In-Depth Precautions and Warning

Drug Warnings

Do not take Tolsama 15 Tablet 4's if you are allergic to any of its contents, if you have raised liver enzymes in the blood, very low blood volume, if there is no urine production, if you cannot tell that you are thirsty. Inform your doctor if you have liver disease, difficulty in urination, diabetes, high levels of uric acid, advanced kidney disease or if you have to restrict fluid intake due to certain medical conditions. Do not take Tolsama 15 Tablet 4's if you are pregnant as it may cause foetal harm. Consult your doctor before taking Tolsama 15 Tablet 4's if you are breastfeeding. Tolsama 15 Tablet 4's is not recommended for children below 18 years as efficacy and safety have not been established. Tolsama 15 Tablet 4's may cause dizziness, so drive with caution. Avoid consuming alcohol as it might cause increased dizziness. 

Drug Interactions

Drug-Drug Interaction: Tolsama 15 Tablet 4's may interact with antibiotic (clarithromycin, telithromycin, sulfamethoxazole, trimethoprim), anti-fungal (ketoconazole, itraconazole), anti-HIV (ritonavir, indinavir, nelfinavir, saquinavir), antidepressant (nefazodone), aldosterone receptor antagonist (spironolactone), angiotensin receptor inhibitor (valsartan, sacubitril), blood thinner (heparin).

Drug-Food Interaction: Avoid consuming grapefruit juice and St. John’s wort (herbal supplement used to treat depression) while taking Tolsama 15 Tablet 4's. 

Drug-Disease Interaction: Inform your doctor if you have liver disease, difficulty in urination, diabetes, high levels of uric acid or kidney disease.

Drug-Drug Interactions Checker List:

  • CLARITHROMYCIN
  • TELITHROMYCIN
  • SULPHAMETHOXAZOLE+TRIMETHOPRIM
  • KETOCONAZOLE
  • ITRACONAZOLE
  • RITONAVIR
  • INDINAVIR
  • SAQUINAVIR
  • NELFINAVIR
  • NEFAZODONE
  • SPIRONOLACTONE
  • VALSARTAN
  • SACUBITRIL
  • HEPARIN

    • Safety Advice

    • Safety Warning

      Alcohol

      unsafe

      Avoid consuming alcohol while taking Tolsama 15 Tablet 4's as it may cause increased dizziness.

    • Safety Warning

      Pregnancy

      unsafe

      Tolsama 15 Tablet 4's belongs to pregnancy category C. Tolsama 15 Tablet 4's is not recommended for use in pregnant women as it may cause foetal harm. Women of childbearing age must use effective contraception while taking Tolsama 15 Tablet 4's.

    • Safety Warning

      Breast Feeding

      unsafe

      Tolsama 15 Tablet 4's is not recommended for use in breastfeeding women. Consult your doctor if you are breastfeeding; your doctor will decide whether Tolsama 15 Tablet 4's can be taken by breastfeeding mothers or not.

    • Safety Warning

      Driving

      caution

      Tolsama 15 Tablet 4's may cause dizziness, weakness and tiredness. Do not drive or operate heavy machinery if you feel dizzy.

    • Safety Warning

      Liver

      caution

      Dose adjustment may be needed. Tolsama 15 Tablet 4's should be used with caution in patients with liver impairment/liver disease. Please consult your doctor if you have liver problems or any concerns regarding this.

    • Safety Warning

      Kidney

      caution

      Tolsama 15 Tablet 4's should be used with caution in patients with kidney impairment/kidney disease. Please consult your doctor if you have kidney problems or any concerns regarding this.

    • Safety Warning

      Children

      unsafe

      Tolsama 15 Tablet 4's is not recommended for children below 18 years as efficacy and safety have not been established.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Eat a diet rich in whole grains, vegetables, and fruits.
    • Avoid smoking and alcohol consumption.
    • Maintain a healthy weight with proper diet and exercise.
    • Manage stress with meditation, yoga, and massage.
    • Drink plenty of fluids.
    • Rehydration beverages that contain electrolytes are also helpful.

    Special Advise

    • Regular monitoring of liver functioning and electrolyte levels while taking Tolsama 15 Tablet 4's is advised.
    • Treatment with Tolsama 15 Tablet 4's should be started and re-started in a hospital or in the presence of a healthcare professional to monitor the sodium levels in your blood closely.

    Other Information (TOL0086)

    This item is Not Returnable.

    Expires on or after - Apr-24

    Patients Concern

    Disease/Condition Glossary

    Hyponatremia: Sodium is an important electrolyte that helps in maintaining water balance in and around the cells. It helps in proper nerve, muscle functioning and maintains stable blood pressure levels. Low levels of sodium in the blood are referred to as hyponatremia. Normal levels of sodium are 135-145 milliequivalance per litre. Hyponatremia occurs when the level is below 135mEq/L. Symptoms include weakness, tiredness, nausea, vomiting, headache, irritability, confusion and muscle spasms.

    Autosomal Dominant Polycystic Kidney Disease (ADPKD): It is an inherited disorder in which cysts are developed in the kidney. These cysts are non-cancerous sacs that contain a water-like fluid which puts pressure on the surrounding tissues, leading to reduced kidney function. Symptoms include high blood pressure, swollen abdomen, and back or side pain.

    FAQs

    How does Tolsama 15 Tablet 4's work?

    Tolsama 15 Tablet 4's works by blocking the effect of vasopressin, a hormone which is involved in the formation of cysts in ADPKD patients. By blocking the effect of vasopressin, Tolsama 15 Tablet 4's slows down the development of cysts in kidneys, reduces the symptoms of the disease, and increases urine production. Thereby increases serum sodium concentrations.

    How to cope with dry mouth?

    Dry mouth could be a side-effect of Tolsama 15 Tablet 4's. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly and chewing sugar-free gum/candy might help in stimulating saliva and thereby prevents drying of the mouth.

    Does Tolsama 15 Tablet 4's cause diarrhoea?

    Diarrhoea could be a side-effect of Tolsama 15 Tablet 4's. Drink plenty of fluid to prevent dehydration if you experience diarrhoea. Consult your doctor if you have severe diarrhoea or if you find blood in stools.

    Does Tolsama 15 Tablet 4's cause liver problems?

    Tolsama 15 Tablet 4's may cause the liver to not work properly. Consult your doctor immediately if you experience nausea, vomiting, fever, loss of appetite, abdominal pain, tiredness, dark urine, jaundice, itching and flu-like symptoms.

    How to cope with side-effects such as thirst?

    Tolsama 15 Tablet 4's may cause water loss due to increased urine production. This might result in side-effects such as thirst, dry mouth and kidney problems. To prevent this, drink plenty of water regularly. Drink 1-2 glasses of water before going to bed even though you are not thirsty. Special care must be taken in patients with diseases that might reduce fluid intake.

    I am diabetic, can I take Tolsama 15 Tablet 4's?

    Consult your doctor before taking Tolsama 15 Tablet 4's if you are diabetic as Tolsama 15 Tablet 4's might increase the blood sugar levels. Regular monitoring of blood glucose levels while taking Tolsama 15 Tablet 4's is advised.

    PRODUCT SUBSTITUTES

    Tolsama 15 Tablet 4's

    Country Of Origin

    INDIA

    Manufacturer/Marketer address

    MSN Laboratories Pvt.Ltd., MSN House, Plot No: C-24, Industrial Estate, Sanathnagar, Hyderabad - 18 Telangana, INDIA

    Disclaimer

    While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

    Price :₹482.80

    MRP ₹568

    15%off

    (Inclusive of all taxes)

    Provide Delivery Location

    Strip

    4 Tablet in 1 Strip