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  1. Home
  2. Medicine

  3. Topafix-25 Tablet 10's

Prescription drug
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Topafix-25 Tablet 10's, Pack of 10 TabletS
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Extra 15% Off with Bank Offers

Composition :

TOPIRAMATE-25MG

Manufacturer/Marketer :

Jagsam Pharma

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Topafix-25 Tablet

Topafix-25 Tablet belongs to a group of medications called antiepileptics/anticonvulsants, primarily used to treat epilepsy (seizures/fits). It is also used in the prevention of migraine headaches.

Topafix-25 Tablet contains Topiramate, which works by restoring the balance of neural activity and reducing the spread of seizure activity in the brain. By controlling the electrical activity of the brain, Topafix-25 Tablet helps control seizures and relieve the symptoms of migraine.

You may experience common side effects, such as dizziness, drowsiness, loss of appetite, nausea, tiredness, confusion, cognitive impairment, fever, flushing, and tingling in the legs and arms. If any of these side effects persist or worsen, please consult your doctor.

Before taking Topafix-25 Tablet , inform your doctor if you are allergic to any of its ingredients. Do not stop taking Topafix-25 Tablet without consulting your doctor, as sudden withdrawal may lead to uncontrolled seizures.

Uses of Topafix-25 Tablet

Topafix-25 Tablet is used in the treatment of epilepsy (seizures/fits) and for the prevention of migraine. The detailed uses of Topafix-25 Tablet are as follows:

  • Monotherapy for Epilepsy: Topafix-25 Tablet is used alone in adults and children over 2 years who have specific types of seizures, like partial (focal) seizures or tonic-clonic (full-body) seizures.
  • Adjunctive Therapy for Epilepsy: Topafix-25 Tablet is also used in combination with other seizure medications in adults and children over 2 years to treat partial seizures, tonic-clonic seizures, or seizures associated with Lennox-Gastaut syndrome (a type of childhood epilepsy).
  • Preventive Therapy for Migraine: Topafix-25 Tablet helps prevent migraine headaches in adults and children over 12 years, but it does not treat acute migraine attacks once it has started.
  • Weight management: Topiramate is also used off-label to manage weight loss. It is used as an adjunct therapy for obesity management.

Have a query?

Directions for Use

  • Topafix-25 Tablet can be taken with or without food.
  • It is usually taken 1-2 times daily; however, your doctor may adjust the dose based on your medical condition.
  • Swallow Topafix-25 Tablet as a whole with a glass of water.
  • Do not crush or chew this medication.

Medicinal Benefits

  • Topafix-25 Tablet belongs to the class of medicines called antiepileptics/anticonvulsants. It is primarily used to treat epilepsy and prevent migraine headaches.
  • In epilepsy, Topafix-25 Tablet helps control and prevent different types of seizures, including partial-onset (focal) seizures, primary generalised tonic-clonic seizures, and seizures associated with Lennox-Gastaut syndrome.
  • It works by reducing the abnormal electrical activity in the brain, thereby preventing the occurrence of seizures.
  • In migraine, Topafix-25 Tablet helps reduce the frequency and severity of migraine attacks by calming overactive nerve cells in the brain.
  • Topafix-25 Tablet stabilises brain activity by blocking voltage-dependent sodium and calcium channels and enhancing the action of gamma-aminobutyric acid (GABA), a natural chemical that prevents excessive nerve stimulation.
  • Topiramate has appetite-suppressing properties, making it suitable for weight loss under medical supervision.

How Topafix-25 Tablet Works

Topafix-25 Tablet contains Topiramate, which works by restoring the balance of neural activity and reducing the spread of seizure activity in the brain. By controlling the electrical activity of the brain, Topafix-25 Tablet helps control seizures and relieves the symptoms of migraine.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Topafix-25 Tablet
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Managing depression as a side effect of medication: a comprehensive guide.
  • Remember, managing depression as a side effect of medication requires patience, persistence, and collaboration with your healthcare team.
  • Tell your doctor about your depression symptoms to adjust medication.
  • Consult a therapist or counsel for emotional support.
  • Engage in regular exercise to release endorphins (neurotransmitters).
  • Practice stress-reducing techniques like meditation and deep breathing.
  • Build a support network of friends, family, and support groups.
  • Establish a consistent sleep schedule.
  • Eat a nutritious diet rich in fruits, vegetables, and whole grains.
  • Limit or avoid alcohol and recreational substances.
  • Keep a mood journal to track symptoms and progress.
  • Change positions or take a break from activity to relieve symptoms.
  • Avoid postures that put a lot of pressure on just one area of the body.
  • If you have vitamin deficiency, take supplements or change your diet.
  • Exercise regularly like cycling, walking or swimming.
  • Avoid sitting with your legs crossed.
  • Clench and unclench your fists and wiggle your toes.
  • Massage the affected area.
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
Here are the steps to manage the medication-triggered Common Cold:
  • Inform your doctor about the common cold symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Drink plenty of fluids, such as warm water or soup, to help thin out mucus.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.

What if I have taken an overdose of Topafix-25 Tablet

Do not take more than the prescribed dose of Topafix-25 Tablet , as it may lead to an overdose. The symptoms of an overdose include drowsiness, blurred vision, speech disturbance, convulsions (fits), double vision, abnormal coordination, stupor (a state of insensibility or near-unconsciousness), stomach pain, low blood pressure, lethargy, mental impairment, depression, agitation, and dizziness. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

  • Do not take Topafix-25 Tablet if you are allergic to any of its ingredients.
  • Inform your doctor if you have ever had kidney problems (such as kidney stones or undergone dialysis), glaucoma (increased eye pressure), metabolic acidosis (excess acid in the blood), growth problems, breathing problems, diarrhoea, suicidal thoughts, mood disturbances, bone disorders (such as osteoporosis or osteomalacia), liver disease, or a blood disorder (such as acute porphyria).
  • Do not stop taking Topafix-25 Tablet without consulting your doctor, as sudden withdrawal may lead to uncontrolled seizures.
  • Topafix-25 Tablet is not recommended during pregnancy, as it may increase the risk of birth defects (like cleft palate and cleft lip) in the unborn baby.
  • Topafix-25 Tablet may pass into breast milk, so consult your doctor to determine whether it is safe to breastfeed while taking Topafix-25 Tablet .
  • If your baby is unusually sleepy, feeds poorly, or has diarrhoea, consult your doctor promptly.
  • Avoid consuming alcohol while taking Topafix-25 Tablet , as it may worsen the side effects like dizziness and drowsiness.
  • Topafix-25 Tablet may impair your vision, thinking, and motor skills; therefore, do not drive or operate machines until you know how this medication affects you.
  • Let your doctor know if you are taking any other medicines or have pre-existing medical conditions.

Drug-Drug Interactions

verifiedApollotooltip
TopiramateOlanzapine
Severe
TopiramateDisopyramide
Severe

Drug-Drug Interactions

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TopiramateOlanzapine
Severe
How does the drug interact with Topafix-25 Tablet:
Combining Olanzapine with Topafix-25 Tablet can increase the risk of overheating and reduced sweating.

How to manage the interaction:
Taking Olanzapine with Topafix-25 Tablet together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you have any symptoms like decreased sweating, fever, drowsiness, dizziness, or lightheadedness consult the doctor immediately. Avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medications affect you and do not discontinue any medications without consulting your doctor.
TopiramateDisopyramide
Severe
How does the drug interact with Topafix-25 Tablet:
Combining Disopyramide with Topafix-25 Tablet can increase the risk of overheating and reduced sweating.

How to manage the interaction:
Co-administration of Topafix-25 Tablet with Disopyramide can possibly result in an interaction, but it can be taken if your doctor has advised it. Your doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without a doctor's advice.
TopiramateBuprenorphine
Severe
How does the drug interact with Topafix-25 Tablet:
When buprenorphine is used with Topafix-25 Tablet, it may lead to significant adverse effects such as respiratory difficulties, unconsciousness.

How to manage the interaction:
Concomitant administration of buprenorphine alongside Topafix-25 Tablet can result in an interaction, it can be taken if a doctor has advised it. Do not exceed the doses, frequency, or duration of usage advised by a doctor. You should avoid driving or operating hazardous machinery until you're aware of how these medications effect you. Consult a doctor if you have any questions or concerns. Do not discontinue any medications without consulting a doctor.
TopiramateAripiprazole
Severe
How does the drug interact with Topafix-25 Tablet:
Topafix-25 Tablet can cause increased body temperature and decreased sweating, and these effects may be worsened when combined with medications like aripiprazole.

How to manage the interaction:
Co-administration of Aripiprazole with Topafix-25 Tablet can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience drowsiness, dizziness, or lightheadedness, consult the doctor immediately. Avoid tasks that need mental attention, such as driving or operating dangerous machinery. Drink plenty of water when it's hot out and while you're exercising, and get medical assistance if you have reduced sweating or a fever. Do not discontinue any medications without consulting a doctor.
TopiramateClomipramine
Severe
How does the drug interact with Topafix-25 Tablet:
Topafix-25 Tablet can cause increased body temperature and decreased sweating, and these effects may be worsened when combined with medications like clomipramine.

How to manage the interaction:
Although taking Topafix-25 Tablet and Clomipramine together can cause an interaction, it can be taken if your doctor has suggested it. Do not stop using any medications without a doctor's advice.
TopiramateClemastine
Severe
How does the drug interact with Topafix-25 Tablet:
Topafix-25 Tablet can cause increased body temperature and decreased sweating, and these effects may be worsened when combined with medications like clemastine.

How to manage the interaction:
Co-administration of Clemastine with Topafix-25 Tablet can possibly result in an interaction, but it can be taken if your doctor has advised it. If you're having any of these symptoms, like less sweating, feeling hotter, heat stroke, feeling sleepy, dizzy, or lightheaded, it's important to contact your doctor immediately. Do not stop using any medications without talking to your doctor.
TopiramateDesipramine
Severe
How does the drug interact with Topafix-25 Tablet:
Topafix-25 Tablet can cause increased body temperature and decreased sweating, and these effects may be worsened when combined with medications like desipramine.

How to manage the interaction:
Although there is a possible interaction between Topafix-25 Tablet and Desipramine, you can take these medicines together if prescribed by your doctor. Do not stop using any medications without talking to your doctor.
TopiramateDiphenhydramine
Severe
How does the drug interact with Topafix-25 Tablet:
Topafix-25 Tablet can induce elevated body temperature and decreased sweating, which can be exacerbated when combined with drugs that have similar effects, such as diphenhydramine.

How to manage the interaction:
Although taking Diphenhydramine with Topafix-25 Tablet can possibly result in an interaction, they can be taken together if prescribed by your doctor. It is essential to stay hydrated by drinking enough fluids, especially in hot weather and when doing physical activity. Contact your doctor immediately if you notice decreased sweating, fever, dizziness, drowsy, or lightheadedness. Do not discontinue using any medications without consulting a doctor.
TopiramateBenzatropine
Severe
How does the drug interact with Topafix-25 Tablet:
Topafix-25 Tablet can cause increased body temperature and decreased sweating, and these effects may be worsened when combined with medications like benzatropine.

How to manage the interaction:
Co-administration of Benzatropine with Topafix-25 Tablet can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience drowsiness, dizziness, or lightheadedness, consult your doctor immediately. Avoid tasks that need mental attention, such as driving or operating dangerous machinery. Drink plenty of water when it's hot out and while you're exercising, and get medical assistance if you have reduced perspiration or a fever. Do not discontinue any medications without consulting your doctor.
TopiramateAmitriptyline
Severe
How does the drug interact with Topafix-25 Tablet:
Coadministration of Amitriptyline and Topafix-25 Tablet may cause increased body temperature and decreased sweating.

How to manage the interaction:
Amitriptyline and sodium oxybate interact, however if a doctor prescribes them, they can still be taken. Consult a doctor if you have symptoms like sleepiness, dizziness, lightheadedness, confusion, depression, low blood pressure, slow or rapid breathing, or impairment in thinking. Never stop taking any medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a balanced diet that consists of good fats, proteins, carbohydrates, vegetables, and fruit, which helps the body and brain work properly and keeps a person healthy and energetic.
  • Fatigue is one of the primary reasons that trigger seizures in the body, so sleeping properly can help relax the brain.
  • One should avoid the consumption of alcohol as it can trigger seizures in patients. Even one or two glasses can trigger epilepsy and worsen the side effects of Topafix-25 Tablet .
  • Maintain your happiness and avoid taking emotional stress, as it can trigger seizures. People who maintain healthy stress levels have reported that they have responded well to the medicine.

Habit Forming

No

Therapeutic Class

ANTICONVULSANT

Topafix-25 Tablet Substitute

Substitutes safety advice
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Alcohol

Caution

Avoid consuming alcohol while taking Topafix-25 Tablet , as it may worsen the side effects like dizziness and drowsiness.

bannner image

Pregnancy

Unsafe

Topafix-25 Tablet is not recommended during pregnancy, as it may increase the risk of birth defects (like cleft palate and cleft lip) in the unborn baby.

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Breast Feeding

Caution

Topafix-25 Tablet may pass into breast milk, so consult your doctor to determine whether it is safe to breastfeed while taking Topafix-25 Tablet . If your baby is unusually sleepy, feeds poorly, or has diarrhoea, consult your doctor promptly.

bannner image

Driving

Caution

Topafix-25 Tablet may impair your vision, thinking, and motor skills; therefore, do not drive or operate machines until you know how this medication affects you.

bannner image

Liver

Consult your doctor

Topafix-25 Tablet should be used with caution in patients with liver disease, as impaired liver function may reduce the medication's clearance. Therefore, the dosage may need to be reduced in patients with liver disease.

bannner image

Kidney

Consult your doctor

Topafix-25 Tablet should be used with caution in patients with kidney disease, as the dosage may need to be adjusted in patients with kidney impairment.

bannner image

Children

Safe if prescribed

Topafix-25 Tablet is safe to use in children above 2 years only if prescribed by the doctor.

FAQs

Topafix-25 Tablet is an anticonvulsant medication primarily used in the treatment of epilepsy (seizures/fits). It is also used in the prevention of migraine.

Topafix-25 Tablet works by restoring the balance of neural activity and reducing the spread of seizure activity in the brain. By controlling the electrical activity of the brain, Topafix-25 Tablet helps control seizures.

No, you should take rest after taking Topafix-25 Tablet . Topafix-25 Tablet may impair your vision, thinking, and motor skills, so avoid doing any task that requires mental alertness.

Topafix-25 Tablet acts by decreasing the spread of seizure activity in the brain. It also restores the normal balance of neurons, which in turn calms the brain. In epilepsy, cells present in the brain talk to each other by generating electric signals. When these cells fail to work properly or work faster than normal then it causes seizures. Topafix-25 Tablet slows down these electrical signals, thereby preventing or controlling seizures. While in migraine, Topafix-25 Tablet calms the overactive nerve cells in the brain that are responsible for triggering migraine attacks.

Yes, the use of Topafix-25 Tablet is safe for long-term use if suggested by the doctor.

Yes, Topafix-25 Tablet may affect the working of contraceptives that include the combined pill, vaginal ring, patches, progestogen-only contraceptive pill, and emergency contraception. Tell your doctor if you are using any type of contraceptives, as they may suggest using different types of contraceptives or combined hormonal contraceptives.

Generally, one should avoid consuming alcohol while taking Topafix-25 Tablet as it may make a person feel sleepy or tired and can cause seizures in some people with epilepsy.

Yes, studies have shown that Topafix-25 Tablet can cause hair loss (alopecia), but it is not a common side effect. If this happens, please consult your doctor and seek appropriate treatment.

Feeling sleepy is one of the most common side effects of Topafix-25 Tablet . It does not require medical attention, is usually mild and goes away over time. Consult the doctor if any of these side effects continue or worsen with time.

Do not stop taking Topafix-25 Tablet abruptly unless your doctor instructs you to. If you're using it to prevent migraines, your condition may worsen temporarily after you stop taking it. If you are using Topafix-25 Tablet for epilepsy, you may get seizures when you stop taking it. To prevent these withdrawal symptoms, your doctor may gradually reduce the dose of your Topafix-25 Tablet if required.

Take Topafix-25 Tablet for as long as prescribed by your doctor. The duration of treatment with Topafix-25 Tablet depends on the medical condition you are being treated for and your response to the treatment.

No, Topafix-25 Tablet is not intended to treat anxiety. It is mainly indicated for seizures.

The severe side effects caused by Topafix-25 Tablet include signs of glaucoma (blurred vision, difficulty seeing, and eye pain), kidney stones and a kidney infection (pain in your back, belly, or side, a burning sensation when you pee, or cloudy or smelly pee), metabolic acidosis (feeling sleepy, losing your appetite, and having an irregular heartbeat), and not sweating (especially in children). If this happens, consult your doctor immediately and seek medical attention.

Taking valproic acid when you are also taking Topafix-25 Tablet can cause your body temperature to drop to less than 95°F or 350C or cause tiredness, confusion, or coma. Taking these medicines may also raise the levels of ammonia in your blood. So, do not take these medications together. If you are required to, your doctor may guide you in taking them appropriately.

Topafix-25 Tablet is safe for children above two years of age only if prescribed by the doctor.

Weight loss and loss of appetite (anorexia) were two of the most commonly reported side effects. If you experience significant changes, seek medical advice from your healthcare professional.

The common side effects of Topafix-25 Tablet include dizziness, drowsiness, loss of appetite, nausea, tiredness, confusion, cognitive impairment, fever, flushing, and tingling in the legs and arms. Most of these side effects do not require medical attention and will gradually resolve on their own. If any of these side effects persist or worsen, please consult your doctor.

Topiramate may be used for weight management. However, this is an off-label use and it should be used for weight management only if advised by your doctor.

Country of origin

India

Manufacturer/Marketer address

Shop No-2, Plot No-4, Sector-11, Balaji Heights, Sanpada, Navi Mumbai, Maharashtra - 400705, India
Other Info - TOP0579

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Oct 7, 2025 | 3:32 PM IST

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Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/020844s041lbl.pdf
  2. https://glenmarkpharma-us.com/wp-content/uploads/Topiramate-Tablets-USP-Medication-Guide-1.pdf
  3. https://www.medicines.org.uk/emc/medicine/6768#gref
  4. https://www.drugs.com/mtm/topiramate.html
  5. https://medlineplus.gov/druginfo/meds/a697012.html
  6. https://www.nhs.uk/medicines/topiramate/pregnancy-breastfeeding-and-fertility-while-taking-topiramate/

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