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  3. Topexid-25 Tablet 10's

Topexid-25 Tablet 10's, Pack of 10 TabletS
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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Topexid-25 Tablet is an anticonvulsant medication primarily used in the treatment of epilepsy (seizures/fits). It is also used in the prevention of migraine. It contains Topiramate, which works by controlling the electrical activity of the brain. Thereby, it controls seizures and relieves the symptoms of migraine. In some cases, it may cause side effects such as dizziness, drowsiness, loss of appetite, nausea, tiredness, confusion, cognitive impairment, fever, flushing, and tingling of the legs and arms. Before taking this medication, inform your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and any pre-existing medical conditions.

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Composition :

TOPIRAMATE-25MG

Manufacturer/Marketer :

Adivis Pharma Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Topexid-25 Tablet

Topexid-25 Tablet belongs to a group of medications called antiepileptics/anticonvulsants,' primarily used to treat epilepsy (seizures/fits). It is also used in the prevention of migraine headaches. Epilepsy is a chronic disorder that is responsible for causing unprovoked, recurrent seizures in the body. A seizure is a sudden attack in the brain that makes a person lose control of their actions. Migraine is a mental condition that often causes intense or debilitating headaches with difficulty speaking, nausea, vomiting, and sensitivity to light or sound.

Topexid-25 Tablet contains Topiramate, which works by restoring the balance of neural activity and reducing the spread of seizure activity in the brain. By controlling the electrical activity of the brain, Topexid-25 Tablet helps control seizures and relieves the symptoms of migraine.

Take Topexid-25 Tablet exactly as prescribed. Your doctor will determine the dosage and timing of Topexid-25 Tablet based on the severity of your medical condition. You may experience common side effects, such as dizziness, drowsiness, loss of appetite, nausea, tiredness, confusion, cognitive impairment, fever, flushing, and tingling in the legs and arms. Most of these side effects do not require medical attention and will gradually resolve on their own. If any of these side effects persist or worsen, please consult your doctor.

Before taking Topexid-25 Tablet , inform your doctor if you are allergic to any of its ingredients. Do not stop taking Topexid-25 Tablet without consulting your doctor, as sudden withdrawal may lead to uncontrolled seizures. Inform your doctor if you have ever had glaucoma (increased eye pressure), metabolic acidosis (excess acid in the blood), diarrhoea, suicidal thoughts, bone disorders, acute porphyria (a blood disorder), or lung, liver, or kidney problems. Topexid-25 Tablet is not recommended during pregnancy, as it may increase the risk of birth defects in the unborn baby. Topexid-25 Tablet may pass into breast milk, so consult your doctor to determine whether it is safe to breastfeed while taking Topexid-25 Tablet .

Uses of Topexid-25 Tablet

Topexid-25 Tablet is used in the treatment of epilepsy (seizures/fits) and for the prevention of migraine. The detailed uses of Topexid-25 Tablet are as follows:<br/> • Monotherapy for Epilepsy: Topexid-25 Tablet is used alone in adults and children over 2 years who have specific types of seizures, like partial (focal) seizures or tonic-clonic (full-body) seizures.<br/> • Adjunctive Therapy for Epilepsy: Topexid-25 Tablet is also used in combination with other seizure medications in adults and children over 2 years to treat partial seizures, tonic-clonic seizures, or seizures associated with Lennox-Gastaut syndrome (a type of childhood epilepsy).<br/> • Preventive Therapy for Migraine: Topexid-25 Tablet helps prevent migraine headaches in adults and children over 12 years, but it does not treat acute migraine attacks once it has started.<br/>

Directions for Use

  • Topexid-25 Tablet can be taken with or without food.
  • It is usually taken 1-2 times daily; however, your doctor may adjust the dose based on your medical condition. 
  • Swallow Topexid-25 Tablet as a whole with a glass of water.
  • Do not crush or chew this medication.

Medicinal Benefits

Topexid-25 Tablet is an antiepileptic/anticonvulsant medication primarily used to treat epilepsy, either as monotherapy or adjunctive therapy. In monotherapy for epilepsy, Topexid-25 Tablet is recommended for patients above 2 years of age with partial-onset (focal) or primary generalized tonic-clonic (full-body) seizures. In adjunctive therapy for epilepsy, Topexid-25 Tablet is recommended for patients over 2 years of age with partial seizures, tonic-clonic seizures, and seizures associated with Lennox-Gastaut syndrome (a type of childhood epilepsy). Topexid-25 Tablet is also used to prevent migraine headaches. Topexid-25 Tablet works by blocking the voltage-dependent sodium and calcium channels and increasing the inhibitory actions of a brain chemical called GABA (gamma-aminobutyric acid). In epilepsy, Topexid-25 Tablet helps control the electrical activity of nerves in the brain, thereby preventing or controlling seizures. While in migraine, Topexid-25 Tablet calms the overactive nerve cells in the brain that are responsible for triggering migraine attacks.

How Topexid-25 Tablet Works

Topexid-25 Tablet contains Topiramate, which works by restoring the balance of neural activity and reducing the spread of seizure activity in the brain. By controlling the electrical activity of the brain, Topexid-25 Tablet helps control seizures and relieves the symptoms of migraine.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Topexid-25 Tablet
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Managing depression as a side effect of medication: a comprehensive guide.
  • Remember, managing depression as a side effect of medication requires patience, persistence, and collaboration with your healthcare team.
  • Tell your doctor about your depression symptoms to adjust medication.
  • Consult a therapist or counsel for emotional support.
  • Engage in regular exercise to release endorphins (neurotransmitters).
  • Practice stress-reducing techniques like meditation and deep breathing.
  • Build a support network of friends, family, and support groups.
  • Establish a consistent sleep schedule.
  • Eat a nutritious diet rich in fruits, vegetables, and whole grains.
  • Limit or avoid alcohol and recreational substances.
  • Keep a mood journal to track symptoms and progress.
  • Change positions or take a break from activity to relieve symptoms.
  • Avoid postures that put a lot of pressure on just one area of the body.
  • If you have vitamin deficiency, take supplements or change your diet.
  • Exercise regularly like cycling, walking or swimming.
  • Avoid sitting with your legs crossed.
  • Clench and unclench your fists and wiggle your toes.
  • Massage the affected area.
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
Here are the steps to manage the medication-triggered Common Cold:
  • Inform your doctor about the common cold symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Drink plenty of fluids, such as warm water or soup, to help thin out mucus.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.

What if I have taken an overdose of Topexid-25 Tablet

Do not take more than the prescribed dose of Topexid-25 Tablet , as it may lead to an overdose. The symptoms of an overdose include drowsiness, blurred vision, speech disturbance, convulsions (fits), double vision, abnormal coordination, stupor (a state of insensibility or near-unconsciousness), stomach pain, low blood pressure, lethargy, mental impairment, depression, agitation, and dizziness. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Do not take Topexid-25 Tablet if you are allergic to any of its ingredients. Inform your doctor if you have ever had kidney problems (such as kidney stones or undergone dialysis), glaucoma (increased eye pressure), metabolic acidosis (excess acid in the blood), growth problems, breathing problems, diarrhoea, suicidal thoughts, mood disturbances, bone disorders (such as osteoporosis or osteomalacia), liver disease, or a blood disorder (such as acute porphyria). Do not stop taking Topexid-25 Tablet without consulting your doctor, as sudden withdrawal may lead to uncontrolled seizures. Topexid-25 Tablet is not recommended during pregnancy, as it may increase the risk of birth defects (like cleft palate and cleft lip) in the unborn baby. Topexid-25 Tablet may pass into breast milk, so consult your doctor to determine whether it is safe to breastfeed while taking Topexid-25 Tablet . If your baby is unusually sleepy, feeds poorly, or has diarrhoea, consult your doctor promptly. Avoid consuming alcohol while taking Topexid-25 Tablet , as it may worsen the side effects like dizziness and drowsiness. Topexid-25 Tablet may impair your vision, thinking, and motor skills; therefore, do not drive or operate machines until you know how this medication affects you.

Drug-Drug Interactions

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TopiramatePromethazine
Severe
TopiramateOxybutynin
Severe

Drug-Drug Interactions

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TopiramatePromethazine
Severe
How does the drug interact with Topexid-25 Tablet:
Taking promethazine with Topexid-25 Tablet can cause increased body temperature and decreased sweating.

How to manage the interaction:
Although there is an interaction between promethazine and amiodarone, they can be taken together if prescribed by your doctor. However, contact a doctor if you experience drowsiness, dizziness, or lightheadedness. Do not discontinue any medications without consulting a doctor.
TopiramateOxybutynin
Severe
How does the drug interact with Topexid-25 Tablet:
Co-administration of Oxybutynin and Topexid-25 Tablet can increase the risk of developing body temperature and decrease sweating.

How to manage the interaction:
Co-administration of Oxybutynin and Topexid-25 Tablet can lead to an interaction, it can be taken if advised by your doctor. Contact your doctor immediately if you experience symptoms like decreased sweating, fever, or drowsiness. Drink plenty of fluids during warm weather and when exercising, and do not discontinue any medications without consulting a doctor.
TopiramatePromazine
Severe
How does the drug interact with Topexid-25 Tablet:
Combining Promazine with Topexid-25 Tablet can increase the risk of overheating and reduced sweating.

How to manage the interaction:
Although there is a possible interaction between Topexid-25 Tablet and Promazine, you can take these medicines together if prescribed by your doctor. Your doctor can recommend other options that won't cause problems when taken together. It's important to be careful and keep a close eye on things. Do not stop using any medications without a doctor's advice.
TopiramateHydroxyzine
Severe
How does the drug interact with Topexid-25 Tablet:
Topexid-25 Tablet can induce elevated body temperature and reduced sweating, which can be exacerbated when taken with hydroxyzine.

How to manage the interaction:
Although taking Hydroxyzine and Topexid-25 Tablet together can cause an interaction, it can be taken if a doctor has suggested it. Drink plenty of water when it's hot out and while you're exercising and get medical assistance if you have reduced perspiration or a fever. Consult a doctor if you experience drowsiness, dizziness, or lightheadedness. Do not stop using any medications without talking to a doctor.
TopiramateCyclobenzaprine
Severe
How does the drug interact with Topexid-25 Tablet:
Coadministration of Topexid-25 Tablet with Cyclobenzaprine can increase the risk of developing side effects.

How to manage the interaction:
There may be a possibility of interaction between Cyclobenzaprine and Topexid-25 Tablet, but it can be taken if prescribed by a doctor. However, if you experience fever, excessive sweating, dizziness, or palpitations . Do not stop using any medications without a doctor's advice.
TopiramateLevonorgestrel
Severe
How does the drug interact with Topexid-25 Tablet:
Topexid-25 Tablet may lower the blood levels and effects of levonorgestrel, making it less effective as a type of birth control.

How to manage the interaction:
Although taking levonorgestrel and Topexid-25 Tablet can lead to an interaction, it can be taken if prescribed by a doctor. If you have been receiving hormone replacement therapy (Levonorgestrel) for menopause, you should contact the doctor if you notice an increase in the frequency or severity of your symptoms, such as hot flashes, vaginal dryness, or irregular bleeding. Do not stop using any medications without talking to a doctor.
TopiramateBenzatropine
Severe
How does the drug interact with Topexid-25 Tablet:
Topexid-25 Tablet can cause increased body temperature and decreased sweating, and these effects may be worsened when combined with medications like benzatropine.

How to manage the interaction:
Co-administration of Benzatropine with Topexid-25 Tablet can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience drowsiness, dizziness, or lightheadedness, consult your doctor immediately. Avoid tasks that need mental attention, such as driving or operating dangerous machinery. Drink plenty of water when it's hot out and while you're exercising, and get medical assistance if you have reduced perspiration or a fever. Do not discontinue any medications without consulting your doctor.
TopiramateCariprazine
Severe
How does the drug interact with Topexid-25 Tablet:
Topexid-25 Tablet can cause increased body temperature and decreased sweating, and these effects may be worsened when combined with cariprazine.

How to manage the interaction:
Although taking Cariprazine and Topexid-25 Tablet together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you're having symptoms like not sweating enough, having a high body temperature, or feeling tired, dizzy, or lightheaded, it's important to contact a doctor. Do not stop using any medications without a doctor's advice.
TopiramateDexchlorpheniramine
Severe
How does the drug interact with Topexid-25 Tablet:
Co-administration of dexchlorpheniramine with Topexid-25 Tablet can increase the risk of Topexid-25 Tablet side effects like increased body temperature and decreased sweating especially in warm weather.

How to manage the interaction:
Taking Dexchlorpheniramine with Topexid-25 Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience decreased sweating, fever, or drowsiness, contact your doctor immediately. Make sure to hydrate yourself during warm weather or after exercise. Do not discontinue any medications without consulting your doctor.
TopiramateGlycopyrrolate
Severe
How does the drug interact with Topexid-25 Tablet:
Coadministration of Glycopyrrolate with Topexid-25 Tablet can increase the risk or severity of side effects like increased body temperature and decreased sweating.

How to manage the interaction:
Taking Glycopyrrolate with Topexid-25 Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience drowsiness, dizziness, lightheadedness, fever, chills, or decreased sweating, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a balanced diet that consists of good fats, proteins, carbohydrates, vegetables, and fruit, which helps the body and brain work properly and keeps a person healthy and energetic.
  • Fatigue is one of the primary reasons that trigger seizures in the body, so sleeping properly can help relax the brain.
  • One should avoid the consumption of alcohol as it can trigger seizures in patients. Even one or two glasses can trigger epilepsy and worsen the side effects of Topexid-25 Tablet .
  • Maintain your happiness and avoid taking emotional stress, as it can trigger seizures. People who maintain healthy stress levels have reported that they have responded well to the medicine.

Habit Forming

No

Therapeutic Class

ANTICONVULSANT

Topexid-25 Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

Avoid consuming alcohol while taking Topexid-25 Tablet , as it may worsen the side effects like dizziness and drowsiness.

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Pregnancy

Unsafe

Topexid-25 Tablet is not recommended during pregnancy, as it may increase the risk of birth defects (like cleft palate and cleft lip) in the unborn baby.

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Breast Feeding

Caution

Topexid-25 Tablet may pass into breast milk, so consult your doctor to determine whether it is safe to breastfeed while taking Topexid-25 Tablet . If your baby is unusually sleepy, feeds poorly, or has diarrhoea, consult your doctor promptly.

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Driving

Caution

Topexid-25 Tablet may impair your vision, thinking, and motor skills; therefore, do not drive or operate machines until you know how this medication affects you.

bannner image

Liver

Consult your doctor

Topexid-25 Tablet should be used with caution in patients with liver disease, as impaired liver function may reduce the medication's clearance. Therefore, the dosage may need to be reduced in patients with liver disease.

bannner image

Kidney

Consult your doctor

Topexid-25 Tablet should be used with caution in patients with kidney disease, as the dosage may need to be adjusted in patients with kidney impairment.

bannner image

Children

Safe if prescribed

Topexid-25 Tablet is safe to use in children above 2 years only if prescribed by the doctor.

Have a query?

FAQs

Topexid-25 Tablet is an anticonvulsant medication primarily used in the treatment of epilepsy (seizures/fits). It is also used in the prevention of migraine.

Topexid-25 Tablet works by restoring the balance of neural activity and reducing the spread of seizure activity in the brain. By controlling the electrical activity of the brain, Topexid-25 Tablet helps control seizures.

No, you should take rest after taking Topexid-25 Tablet . Topexid-25 Tablet may impair your vision, thinking, and motor skills, so avoid doing any task that requires mental alertness.

Topexid-25 Tablet acts by decreasing the spread of seizure activity in the brain. It also restores the normal balance of neurons, which in turn calms the brain. In epilepsy, cells present in the brain talk to each other by generating electric signals. When these cells fail to work properly or work faster than normal then it causes seizures. Topexid-25 Tablet slows down these electrical signals, thereby preventing or controlling seizures. While in migraine, Topexid-25 Tablet calms the overactive nerve cells in the brain that are responsible for triggering migraine attacks.

Yes, the use of Topexid-25 Tablet is safe for long-term use if suggested by the doctor.

Yes, Topexid-25 Tablet may affect the working of contraceptives that include the combined pill, vaginal ring, patches, progestogen-only contraceptive pill, and emergency contraception. Tell your doctor if you are using any type of contraceptives, as they may suggest using different types of contraceptives or combined hormonal contraceptives.

Generally, one should avoid consuming alcohol while taking Topexid-25 Tablet as it may make a person feel sleepy or tired and can cause seizures in some people with epilepsy.

Yes, studies have shown that Topexid-25 Tablet can cause hair loss (alopecia), but it is not a common side effect. If this happens, please consult your doctor and seek appropriate treatment.

Feeling sleepy is one of the most common side effects of Topexid-25 Tablet . It does not require medical attention, is usually mild and goes away over time. Consult the doctor if any of these side effects continue or worsen with time.

Do not stop taking Topexid-25 Tablet abruptly unless your doctor instructs you to. If you're using it to prevent migraines, your condition may worsen temporarily after you stop taking it. If you are using Topexid-25 Tablet for epilepsy, you may get seizures when you stop taking it. To prevent these withdrawal symptoms, your doctor may gradually reduce the dose of your Topexid-25 Tablet if required.

Take Topexid-25 Tablet for as long as prescribed by your doctor. The duration of treatment with Topexid-25 Tablet depends on the medical condition you are being treated for and your response to the treatment.

No, Topexid-25 Tablet is not intended to treat anxiety. It is mainly indicated for seizures.

The severe side effects caused by Topexid-25 Tablet include signs of glaucoma (blurred vision, difficulty seeing, and eye pain), kidney stones and a kidney infection (pain in your back, belly, or side, a burning sensation when you pee, or cloudy or smelly pee), metabolic acidosis (feeling sleepy, losing your appetite, and having an irregular heartbeat), and not sweating (especially in children). If this happens, consult your doctor immediately and seek medical attention.

Taking valproic acid when you are also taking Topexid-25 Tablet can cause your body temperature to drop to less than 95°F or 350C or cause tiredness, confusion, or coma. Taking these medicines may also raise the levels of ammonia in your blood. So, do not take these medications together. If you are required to, your doctor may guide you in taking them appropriately.

Topexid-25 Tablet is safe for children above two years of age only if prescribed by the doctor.

Weight loss and loss of appetite (anorexia) were two of the most commonly reported side effects. If you experience significant changes, seek medical advice from your healthcare professional.

The common side effects of Topexid-25 Tablet include dizziness, drowsiness, loss of appetite, nausea, tiredness, confusion, cognitive impairment, fever, flushing, and tingling in the legs and arms. Most of these side effects do not require medical attention and will gradually resolve on their own. If any of these side effects persist or worsen, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

P No-19-Wz-5-A-1 Vishnu Garden, Delhi West Delhi Dl 110018 In
Other Info - TOP0582

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jul 22, 2025 | 11:04 AM IST

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Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/020844s041lbl.pdf
  2. https://glenmarkpharma-us.com/wp-content/uploads/Topiramate-Tablets-USP-Medication-Guide-1.pdf
  3. https://www.medicines.org.uk/emc/medicine/6768#gref
  4. https://www.drugs.com/mtm/topiramate.html
  5. https://medlineplus.gov/druginfo/meds/a697012.html
  6. https://www.nhs.uk/medicines/topiramate/pregnancy-breastfeeding-and-fertility-while-taking-topiramate/

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