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  3. Topiroxo 20 Tablet 10's

Topiroxo 20 Tablet 10's, Pack of 10 TABLETS
Topiroxo 20 Tablet 10's, Pack of 10 TABLETS
Topiroxo 20 Tablet 10's, Pack of 10 TABLETS
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Composition :

TOPIROXOSTAT-20MG

Manufacturer/Marketer :

Alkem Laboratories Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Topiroxo 20 Tablet

Topiroxo 20 Tablet is used to treat and manage hyperuricemia (excess uric acid in the blood) and gout. Gout is a chronic condition due to the deposition of uric acid in the joints. It is characterized by intense pain and swelling at the affected joints.

Topiroxo 20 Tablet contains Topiroxostat, which works by inhibiting the enzyme xanthine oxidase (an enzyme essential for the degradation of purine nucleotides to create uric acid), thereby reducing the uric acid level in your body. Thus, it reduces the inflammation caused by uric acid in affected joints, thereby reducing pain, swelling and inflammation.

Topiroxo 20 Tablet should be taken as prescribed by your doctor. The dose of this medicine will be decided by your doctor, depending on your medical condition. This medicine may cause some common side effects such as liver enzyme elevations, upset stomach, diarrhoea, nausea, drowsiness, headache, and vomiting. Most of these side effects are temporary, do not require medical attention, and gradually resolve over time. However, if the side effects persist or worsen, contact your doctor.

Avoid taking Topiroxo 20 Tablet if you are allergic to any of the substances in it. To avoid potential interactions, inform your doctor about your medical and medication history, including herbal and vitamin supplements, before using this medication. Also, inform your doctor if you are pregnant, planning a pregnancy, or breastfeeding. Limited information about using Topiroxo 20 Tablet in children is available, so do not use it without a doctor's advice. Avoid consumption of alcohol while taking Topiroxo 20 Tablet as consuming alcohol may worsen your condition.

Uses of Topiroxo 20 Tablet

Topiroxo 20 Tablet is used in the treatment and management of hyperuricemia and gout. The detailed uses of Topiroxo 20 Tablet are as follows:<br/>• Treatment of hyperuricemia: Topiroxo 20 Tablet helps lower elevated uric acid levels in the blood, reducing the risk of urate crystal formation.<br/>• Treatment of gout: Topiroxo 20 Tablet is used to manage gout by preventing flare-ups and complications associated with excess uric acid.<br/>

Directions for Use

• Topiroxo 20 Tablet can be taken with or without food as advised by your doctor.• It is recommended to take Topiroxo 20 Tablet twice daily; however, follow your doctor's advice regarding the dosage and duration.• Swallow the medicine as a whole with a glass of water.• Do not break, chew or crush Topiroxo 20 Tablet .

Medicinal Benefits

Topiroxo 20 Tablet contains Topiroxostat, a selective xanthine oxidase inhibitor medicine used to treat and manage hyperuricemia (excess of uric acid in the blood) and gout. It works by inhibiting the enzyme xanthine oxidase (an enzyme essential for the degradation of purine nucleotides to create uric acid), thereby reducing the level of uric acid in your body. Thus, it reduces the inflammation caused by uric acid crystals in affected joints, thereby reducing pain, swelling and inflammation.

How Topiroxo 20 Tablet Works

Topiroxo 20 Tablet contains Topiroxostat, which works by inhibiting the enzyme xanthine oxidase (an enzyme essential for the degradation of purine nucleotides to create uric acid), thereby reducing the uric acid level in your body. Thus, it reduces the inflammation caused by uric acid in affected joints, thereby reducing pain, swelling and inflammation.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Topiroxo 20 Tablet

Do not take more than the prescribed dose. Using more medication will not improve your symptoms; instead, they may cause serious side effects or poisoning. If you suspect that you may have overdosed of Topiroxo 20 Tablet or observe any side effects, please go to the emergency department of the closest hospital or nursing home. No specific side effects have been reported under these circumstances.

Drug Warnings

Do not take Topiroxo 20 Tablet if you are allergic to its ingredients. The safety of Topiroxo 20 Tablet in pregnant women is uncertain. As a result, inform your doctor; your doctor will consider the benefits and potential hazards before giving this medication. Topiroxo 20 Tablet is not known if it is excreted in human milk. It should not be used if the potential advantages outweigh the hazards to the newborn. If you are breastfeeding, consult with your doctor before using this medication. This medication may increase your chances of significant heart and blood vessel problems, such as unstable chest discomfort, heart attack, or stroke. Contact your doctor immediately if you experience chest pain, difficulty breathing, a sudden or severe headache, or problems with vision, speech, or walking.

Diet & Lifestyle Advise

  • Adopting a balanced diet is an important lifestyle component in gout therapy or management.
  • A healthy diet generally includes plant-based foods such as vegetables, fruits, legumes, and whole grains.
  • Stay well-hydrated by drinking water.
  • Consume uric acid-lowering foods.  Low-fat dairy products are one example. Calcium-rich foods may help reduce gout attacks while also protecting your bones.
  • Citrus fruits and other vitamin C-rich foods (such as strawberries and peppers) may benefit people with gout. Eating cherries or juice can help minimize gout episodes and pain.
  • Being overweight raises the risk of having gout, while reducing weight reduces the risk.
  • Avoiding purine-rich meals such as red meat, some seafood, and alcohol may help you lower uric acid levels in your blood and lessen your risk of gout attacks.
  • Avoid meals and beverages containing high fructose, and restrict your consumption of naturally sweet fruit juices.
  • Avoid drinking alcohol and quit smoking.

Habit Forming

No

Therapeutic Class

GOUT THERAPY

Topiroxo 20 Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Consult your doctor

It is not known whether consumption of alcohol is safe while taking Topiroxo 20 Tablet . Please consult your doctor for more information.

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Pregnancy

Consult your doctor

The safety of Topiroxo 20 Tablet in pregnant women is unknown. Therefore, please consult your doctor; your doctor will weigh the benefits and potential risks before prescribing this medicine.

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Breast Feeding

Consult your doctor

It is unknown whether Topiroxo 20 Tablet is excreted in human milk. It should not be used while breastfeeding unless the possible benefits outweigh the risks to the infant. If you are breastfeeding, inform your doctor before using this medicine.

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Driving

Consult your doctor

It is not known whether Topiroxo 20 Tablet alters the ability to drive. Please consult your doctor if you experience any symptoms that affect your alertness.

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Liver

Consult your doctor

Limited information is available about using Topiroxo 20 Tablet in patients with liver disease. Inform your doctor before receiving the Topiroxo 20 Tablet if you have a history of liver diseases. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Consult your doctor

Limited information is available about using Topiroxo 20 Tablet in patients with kidney disease. Inform your doctor before receiving the Topiroxo 20 Tablet if you have a history of kidney problems. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Consult your doctor

Limited information about using Topiroxo 20 Tablet in children is available, so do not use it without a doctor's advice.

Have a query?

FAQs

Topiroxo 20 Tablet is used to treat and control hyperuricemia (excess uric acid in the blood) and gout. Gout is a chronic condition due to the deposition of uric acid in the joints. It is characterized by intense pain and swelling at the affected joints.

Topiroxo 20 Tablet contains Topiroxostat, a selective xanthine oxidase inhibitor medicine used to treat and manage hyperuricemia (excess of uric acid in the blood) and gout. It works by inhibiting the enzyme xanthine oxidase (an enzyme essential for the degradation of purine nucleotides to create uric acid), thereby reducing the level of uric acid in your body. Thus, it reduces the inflammation caused by uric acid crystals in affected joints, thereby reducing pain, swelling and inflammation.

This medication is only available with a doctor&amp;#039;s prescription. You must use it only if your doctor prescribes it.

It may take several weeks for your uric acid levels to drop or notice a major reduction.

It is possible to completely control the disease by using medication and diet; lifestyle changes can help cure it.

Changing your diet and lifestyle, such as lowering weight, restricting alcohol, and avoiding foods high in purines (such as red meat or organ meat, which can promote gout flares), may help prevent future attacks.

The best time to take Topiroxo 20 Tablet is as directed by your doctor or according to the instructions provided with the medication.

The exact dose of Topiroxo 20 Tablet may vary based on individual factors such as age, gender, and medical history. Therefore, follow your doctor's instructions regarding the dose and frequency. Do not exceed the recommended dose.

Patients with kidney disease should take Topiroxo 20 Tablet with caution. Therefore, your doctor may recommend regular monitoring of your kidney function and adjusting the dosage to ensure safety.

When taking Topiroxo 20 Tablet , it's essential to take it as prescribed by your doctor, drink plenty of fluids to prevent kidney stones and avoid consuming alcohol. Additionally, caution is advised for patients with liver or kidney disease, as well as pregnant or breastfeeding women, and regular monitoring of liver and kidney function is recommended.

The common side effects of Topiroxo 20 Tablet are liver enzyme elevations, upset stomach, diarrhoea, nausea, drowsiness, headache, and vomiting. Please consult your doctor if any of these side effects persist or worsen.

Country of origin

India

Manufacturer/Marketer address

Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.
Other Info - TOP0499

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 9:22 AM IST

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Reference

  1. https://www.sciencedirect.com/topics/medicine-and-dentistry/topiroxostat
  2. https://go.drugbank.com/drugs/DB01685
  3. https://www.pmda.go.jp/files/000153624.pdf
  4. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045538/#:~:text=Conclusions%3A%20Topiroxostat%20improved%20arterial%20stiffness,inhibitory%20effect%20on%20plasma%20XOR.

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