apollo
0

Welcome User

Login/Sign Up

Home
Buy Medicines
Lab Tests
Doctor Consult
Circle Membership
insurance
Blogs
Contact Us
Privacy Policy
Return & Refunds
Need Help
Terms and Conditions
  1. Home
  2. Medicine

  3. Topoquis 4 mg Injection 4 ml

Topoquis 4 mg Injection 4 ml, Pack of 1
Offers on medicine orders
All offers
axis icici
rxMedicinePrescription drug

Whats That

tooltip

Also Explore

Momverse
Ask Apollo
insurance

Composition :

TOPOTECAN-4MG

Manufacturer/Marketer :

Fresenius Kabi India Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Topoquis 4 mg Injection 4 ml

Topoquis 4 mg Injection 4 ml belongs to a group of medicines called 'anti-cancer/anti-neoplastic agents', used to treat ovarian and small cell lung cancer. On the other hand, it may use to treat advanced cervical cancer if surgery or radiotherapy treatment is not possible. It may sometimes be used to treat other cancers. Ovarian cancer begins in the ovaries (a pair of female reproductive glands in which the ova, or eggs, are formed). Small-cell lung cancer is a disease in which malignant (cancer) cells form in the lung tissues.

Topoquis 4 mg Injection 4 ml contains 'Topotecan'. It works by penetrating into the cell wall and binding to the cell's DNA, stopping it from naturally dividing and functioning, ultimately destroying it. These medicines target cancer cells because they often affect rapidly dividing cells.

The amount of medicine that you will receive depends on many factors, including your height and weight, your general health or other health problems, and the type of cancer or condition being treated. Your doctor will determine your dose and schedule. Topoquis 4 mg Injection 4 ml is prescribed by a doctor experienced in the use of medications to treat cancer. You may sometimes experience nausea, diarrhoea, vomiting, thrombocytopenia (a low platelet count), peripheral neuropathy (nerves malfunction), nephrotoxicity at high doses, and electrolyte disturbances. Most of these side effects of Topoquis 4 mg Injection 4 ml do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

To treat your condition effectually, continue taking Topoquis 4 mg Injection 4 ml for as long as your doctor has prescribed. Do not stop using the Topoquis 4 mg Injection 4 ml midway. Talk to your doctor before taking Topoquis 4 mg Injection 4 ml if you have severe allergic reactions to Topoquis 4 mg Injection 4 ml or other medicines or suffer from severe lung problems, Infections, renal dysfunction, hepatic disorders and blood cell counts are too low. Avoid taking Topoquis 4 mg Injection 4 ml if you are pregnant or breastfeeding because this Topoquis 4 mg Injection 4 ml can cause harmful effects on the unborn baby. Both women and men using this Topoquis 4 mg Injection 4 ml should use birth control to avoid pregnancy.

Uses of Topoquis 4 mg Injection 4 ml

Topoquis 4 mg Injection 4 ml is used in the treatment of ovarian cancer and small-cell lung cancer. The detailed uses of Topoquis 4 mg Injection 4 ml are as follows:<br/>• Ovarian cancer: Topoquis 4 mg Injection 4 ml is effective in treating advanced ovarian cancer that has recurred or is resistant to other treatments, helping to slow tumor growth and manage symptoms.<br/>• Small cell lung cancer: Topoquis 4 mg Injection 4 ml manages recurrent or chemotherapy-sensitive small cell lung cancer, potentially extending survival and improving quality of life.<br/>• Cervical cancer: In certain cases, such as recurrent or metastatic disease, Topoquis 4 mg Injection 4 ml can also be used to control tumor growth and alleviate symptoms.<br/>

Directions for Use

• Topoquis 4 mg Injection 4 ml is prescribed and administered based on your medical condition and treatment plan as determined by your doctor.• This injection is given only by qualified healthcare professionals experienced in administering cancer therapies.• It must not be self-administered, as it requires careful handling and monitoring during and after administration.• You will be closely monitored during treatment to ensure your safety and treatment effectiveness.

Medicinal Benefits

Topoquis 4 mg Injection 4 ml contains 'Topotecan', which belongs to a group of anti-cancer medicines used to treat ovarian cancer and small cell lung cancer. It works by damaging the genetic material (DNA) of the cancer cells, which stops their growth and multiplication. It can be used alone or together with other chemotherapy drugs depending on the type of cancer you have.

How Topoquis 4 mg Injection 4 ml Works

Topoquis 4 mg Injection 4 ml contains 'Topotecan'. It works by penetrating into the cell wall and binding to the cell's DNA, stopping it from naturally dividing and functioning, ultimately destroying it. These medicines target cancer cells because they often affect rapidly dividing cells.

Storage

Store in a cool and dry place away from sunlight
Side effects of Topoquis 4 mg Injection 4 ml
  • Talk to your doctor about medicines to manage neutropenia based on the underlying cause.
  • Avoid contact with people who are sick.
  • Wash your hands regularly with soap and water.
  • Avoid unpasteurized dairy products.
  • Boost your immunity by including immune rich foods in your diet and always remember to stay hydrated.
  • Get sufficient sleep and manage stress which helps in improving white blood cell count.
  • Consult your doctor for an effective treatment to improve the blood cell count and get regular body check up to monitor changes in the count.
  • Try to prevent the factors that cause a decrease in the white blood cells that may lead to impaired immunity.
  • Managing a low platelet count (thrombocytopenia) caused by medication usage requires a multi-step approach. Here are some steps to help manage the condition:
  • Inform your doctor about your low platelet count and medication usage. They will assess the situation and guide the best course of action.
  • Your doctor may recommend adjusting or stopping the medication that is causing a low platelet count. This could involve switching to alternative medication or reducing the dosage.
  • Monitor your platelet count regularly through blood tests to track any changes. This will help the doctor determine the effectiveness of the treatment plan.
  • If an underlying condition, such as infection or inflammation, contributes to the low platelet count, your doctor will treat it.
  • In some cases, alternative treatments like platelet transfusions or medications that stimulate platelet production may be necessary.
  • Avoid risky activities and certain medications; eat a balanced diet with plenty of water to reduce bleeding risk and boost overall health.
  • If you experience severe bleeding or bruising, seek emergency medical attention immediately.
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

What if I have taken an overdose of Topoquis 4 mg Injection 4 ml

Topoquis 4 mg Injection 4 ml is a parenteral formulation, hence the chance of overdose may be less. However, keep track of your medicine as an overdose of Topoquis 4 mg Injection 4 ml may cause serious side effects such as myelosuppression, increased hepatic enzymes, etc. Seek immediate medical attention if you observe any of these side effects. If an overdose is suspected, observe the patient.

Drug Warnings

Topoquis 4 mg Injection 4 ml will be administered by a healthcare professional. To treat your condition effectually, continue taking Topoquis 4 mg Injection 4 ml for as long as your doctor has prescribed. Do not stop Topoquis 4 mg Injection 4 ml midway. Talk to your doctor before taking Topoquis 4 mg Injection 4 ml if you have severe allergic reactions to Topoquis 4 mg Injection 4 ml or other medicines or suffer from severe lung problems, Infections, renal dysfunction, thrombocytopenia (a low platelet count), neutropenia (low white blood cell count), hepatic disorders. Topoquis 4 mg Injection 4 ml should not be employed in patients with severe bone marrow depression or significant bleeding. Avoid taking Topoquis 4 mg Injection 4 ml if you are pregnant or breastfeeding because this Topoquis 4 mg Injection 4 ml can cause harmful effects on the unborn baby. Both women and men using this Topoquis 4 mg Injection 4 ml should use birth control to avoid pregnancy. Peripheral blood counts should be frequently monitored during Topoquis 4 mg Injection 4 ml treatment and appropriate until recovery is achieved. Do not receive any kind of immunization or vaccination without your doctor's approval while taking the Topoquis 4 mg Injection 4 ml.

Drug-Drug Interactions

verifiedApollotooltip
TopotecanCarboplatin
Severe
TopotecanBaricitinib
Severe

Drug-Drug Interactions

Login/Sign Up

TopotecanCarboplatin
Severe
How does the drug interact with Topoquis 4 mg Injection 4 ml:
When carboplatin is used with Topoquis 4 mg Injection 4 ml, it may increase the risk of side effects.

How to manage the interaction:
Co-administration of carboplatin with clozapine can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any unusual symptoms, consult the doctor. Do not discontinue any medications without consulting your doctor.
TopotecanBaricitinib
Severe
How does the drug interact with Topoquis 4 mg Injection 4 ml:
Coadministration of baricitinib and Topoquis 4 mg Injection 4 ml can increase the risk of developing serious infections.

How to manage the interaction:
Although there is an interaction, baricitinib can be taken with Topoquis 4 mg Injection 4 ml if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medications without talking to a doctor.
TopotecanInfliximab
Severe
How does the drug interact with Topoquis 4 mg Injection 4 ml:
Combining Infliximab with Topoquis 4 mg Injection 4 ml can increase the risk and severity of side effects.

How to manage the interaction:
Co-administration of Topoquis 4 mg Injection 4 ml with Infliximab can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience symptoms of fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in sputum, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
TopotecanEtanercept
Severe
How does the drug interact with Topoquis 4 mg Injection 4 ml:
When Etanercept is used with Topoquis 4 mg Injection 4 ml, the likelihood or severity of infection may increase.

How to manage the interaction:
Although there is a possible interaction between Topoquis 4 mg Injection 4 ml and Etanercept, you can take these medicines together if prescribed by a doctor. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
TopotecanThalidomide
Severe
How does the drug interact with Topoquis 4 mg Injection 4 ml:
Taking thalidomide together with Topoquis 4 mg Injection 4 ml may increase the risk of blood clots and other complications.

How to manage the interaction:
Although taking thalidomide and Topoquis 4 mg Injection 4 ml together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.
TopotecanClozapine
Severe
How does the drug interact with Topoquis 4 mg Injection 4 ml:
When Clozapine is taken with Topoquis 4 mg Injection 4 ml, the effect of Clozapine in the blood can go up.

How to manage the interaction:
Although there is a possible interaction between Topoquis 4 mg Injection 4 ml and Clozapine, you can take these medicines together if prescribed by your doctor. If you're having any of these symptoms - infection, fever, chills, diarrhea, sore throat, muscle aches, weight loss, pain or burning during urination - it's important to contact your doctor right away. They may be able to recommend other options that won't cause any problems with your current medications. Do not stop using any medications without a doctor's advice.
TopotecanTofacitinib
Severe
How does the drug interact with Topoquis 4 mg Injection 4 ml:
Taking Tofacitinib with Topoquis 4 mg Injection 4 ml may increase the risk of infection.

How to manage the interaction:
Although there is a possible interaction between Tofacitinib and Topoquis 4 mg Injection 4 ml, you can take these medicines together if prescribed by your doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without first consulting your doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

Login/Sign Up

Diet & Lifestyle Advise

  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Performing yoga may also help in improving both physical and mental health.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
  • Get optimal sleep; rest well.
  • Avoid smoking and alcohol consumption.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugars.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC
bannner image

Alcohol

Unsafe

Avoid alcohol consumption while on treatment with Topoquis 4 mg Injection 4 ml.

bannner image

Pregnancy

Unsafe

Topoquis 4 mg Injection 4 ml should not be used during pregnancy because it can harm your fetus (newborn baby). Both women of childbearing potential and men must use an effective contraception method while taking Topoquis 4 mg Injection 4 ml and at least for six months later treatment. Your doctor will weigh the benefits and risks before prescribing this medicine.

bannner image

Breast Feeding

Unsafe

Topoquis 4 mg Injection 4 ml should not be used during breastfeeding as it passes into the breastmilk and may harm your baby. Hence, if you are breastfeeding, inform your doctor before receiving this medicine.

bannner image

Driving

Caution

Topoquis 4 mg Injection 4 ml may affect your reactions and your ability to drive.Note: Possible side effects of chemotherapy with Topoquis 4 mg Injection 4 ml may occur, such as nausea and vomiting. If you are affected by these side effects, do not drive and/or operate machines that require your alertness.

bannner image

Liver

Caution

If you have had a history or evidence of liver impairment, please inform your doctor before taking the Topoquis 4 mg Injection 4 ml. Your doctor may adjust the dose or prescribe a suitable alternative if necessary based on your condition.

bannner image

Kidney

Caution

If you have had a history or evidence of kidney diseases, please inform your doctor before taking the Topoquis 4 mg Injection 4 ml. Your doctor may adjust the dose or prescribe a suitable alternative if necessary based on your condition.

bannner image

Children

Unsafe

The safety and effectiveness of Topoquis 4 mg Injection 4 ml in pediatric patients have not been established. Please consult your doctor. Your doctor will weigh the benefits and any potential risks before prescribing this medicine.

Have a query?

FAQs

Topoquis 4 mg Injection 4 ml belongs to a group of medicines called anti-cancer drugs used in the treatment of ovarian cancer and small cell lung cancer. It is also used to treat advanced cervical cancer if surgery or radiotherapy treatment is not possible.

Topoquis 4 mg Injection 4 ml contains &#039;Topotecan&#039;. Topotecan works by breaching the cellular wall and binding to the cell’s DNA, preventing the cell from dividing and functioning normally, which eventually kills the cell.

If you are allergic to topotecan or any other ingredients in this medication, are breastfeeding, or have too low blood cell counts, you should not use Topoquis 4 mg Injection 4 ml.

Yes, Topoquis 4 mg Injection 4 ml can cause low neutrophils levels, a type of white blood cells that help fight infections. If your white blood cells become low, you can be at higher risk for infections. Tell your doctor if you develop a fever or have an infection.

Avoid taking Topoquis 4 mg Injection 4 ml if you are pregnant because Topoquis 4 mg Injection 4 ml can cause harmful effects on the unborn baby. Females should follow effective birth control methods during treatment and at least six months after the final dose of Topoquis 4 mg Injection 4 ml.

The live vaccine may not work while on treatment with Topoquis 4 mg Injection 4 ml. Do not have immunizations/vaccinations without talking to your doctor first. Also, avoid contact with people who recently had immunizations /vaccinations.

Topoquis 4 mg Injection 4 ml is used to treat ovarian or small cell lung cancer that has come back after chemotherapy. On the other hand, it can also treat advanced cervical cancer if surgery or radiotherapy treatment is not possible. When treating cervical cancer, Topoquis 4 mg Injection 4 ml is used with another medication called cisplatin.

Country of origin

India

Manufacturer/Marketer address

Fresenius Kabi Ag , Else-Krã¶Ner-Straãÿe 1 , 61352 Bad Homburg , Germany
Other Info - TOP0558

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 7:02 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.medicines.org.uk/emc/files/pil.4159.pdf
  2. https://www.drugs.com/drug-interactions/topotecan.htmlhttp://chemocare.com/chemotherapy/drug-info/Topotecan.aspx#:~:text=What%20Topotecan%20Is%20Used%20For,(small%20cell%20lung%20cancer).
whatsapp Floating Button