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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Topsulant 50mg Tablet is an anticonvulsant medication primarily used in the treatment of epilepsy (seizures/fits). It is also used in the prevention of migraine. It contains Topiramate, which works by controlling the electrical activity of the brain. Thereby, it controls seizures and relieves the symptoms of migraine. In some cases, it may cause side effects such as dizziness, drowsiness, loss of appetite, nausea, tiredness, confusion, cognitive impairment, fever, flushing, and tingling of the legs and arms. Before taking this medication, inform your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and any pre-existing medical conditions.

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Composition :

TOPIRAMATE-50MG

Consume Type :

ORAL

Return Policy :

Not Returnable

About Topsulant 50mg Tablet

Topsulant 50mg Tablet belongs to a group of medications called antiepileptics/anticonvulsants,' primarily used to treat epilepsy (seizures/fits). It is also used in the prevention of migraine headaches. Epilepsy is a chronic disorder that is responsible for causing unprovoked, recurrent seizures in the body. A seizure is a sudden attack in the brain that makes a person lose control of their actions. Migraine is a mental condition that often causes intense or debilitating headaches with difficulty speaking, nausea, vomiting, and sensitivity to light or sound.

Topsulant 50mg Tablet contains Topiramate, which works by restoring the balance of neural activity and reducing the spread of seizure activity in the brain. By controlling the electrical activity of the brain, Topsulant 50mg Tablet helps control seizures and relieves the symptoms of migraine.

Take Topsulant 50mg Tablet exactly as prescribed. Your doctor will determine the dosage and timing of Topsulant 50mg Tablet based on the severity of your medical condition. You may experience common side effects, such as dizziness, drowsiness, loss of appetite, nausea, tiredness, confusion, cognitive impairment, fever, flushing, and tingling in the legs and arms. Most of these side effects do not require medical attention and will gradually resolve on their own. If any of these side effects persist or worsen, please consult your doctor.

Before taking Topsulant 50mg Tablet, inform your doctor if you are allergic to any of its ingredients. Do not stop taking Topsulant 50mg Tablet without consulting your doctor, as sudden withdrawal may lead to uncontrolled seizures. Inform your doctor if you have ever had glaucoma (increased eye pressure), metabolic acidosis (excess acid in the blood), diarrhoea, suicidal thoughts, bone disorders, acute porphyria (a blood disorder), or lung, liver, or kidney problems. Topsulant 50mg Tablet is not recommended during pregnancy, as it may increase the risk of birth defects in the unborn baby. Topsulant 50mg Tablet may pass into breast milk, so consult your doctor to determine whether it is safe to breastfeed while taking Topsulant 50mg Tablet.

Uses of Topsulant 50mg Tablet

Topsulant 50mg Tablet is used in the treatment of epilepsy (seizures/fits) and for the prevention of migraine. The detailed uses of Topsulant 50mg Tablet are as follows:<br/> • Monotherapy for Epilepsy: Topsulant 50mg Tablet is used alone in adults and children over 2 years who have specific types of seizures, like partial (focal) seizures or tonic-clonic (full-body) seizures.<br/> • Adjunctive Therapy for Epilepsy: Topsulant 50mg Tablet is also used in combination with other seizure medications in adults and children over 2 years to treat partial seizures, tonic-clonic seizures, or seizures associated with Lennox-Gastaut syndrome (a type of childhood epilepsy).<br/> • Preventive Therapy for Migraine: Topsulant 50mg Tablet helps prevent migraine headaches in adults and children over 12 years, but it does not treat acute migraine attacks once it has started.<br/>

Directions for Use

  • Topsulant 50mg Tablet can be taken with or without food.
  • It is usually taken 1-2 times daily; however, your doctor may adjust the dose based on your medical condition. 
  • Swallow Topsulant 50mg Tablet as a whole with a glass of water.
  • Do not crush or chew this medication.

Medicinal Benefits

Topsulant 50mg Tablet is an antiepileptic/anticonvulsant medication primarily used to treat epilepsy, either as monotherapy or adjunctive therapy. In monotherapy for epilepsy, Topsulant 50mg Tablet is recommended for patients above 2 years of age with partial-onset (focal) or primary generalized tonic-clonic (full-body) seizures. In adjunctive therapy for epilepsy, Topsulant 50mg Tablet is recommended for patients over 2 years of age with partial seizures, tonic-clonic seizures, and seizures associated with Lennox-Gastaut syndrome (a type of childhood epilepsy). Topsulant 50mg Tablet is also used to prevent migraine headaches. Topsulant 50mg Tablet works by blocking the voltage-dependent sodium and calcium channels and increasing the inhibitory actions of a brain chemical called GABA (gamma-aminobutyric acid). In epilepsy, Topsulant 50mg Tablet helps control the electrical activity of nerves in the brain, thereby preventing or controlling seizures. While in migraine, Topsulant 50mg Tablet calms the overactive nerve cells in the brain that are responsible for triggering migraine attacks.

How Topsulant 50mg Tablet Works

Topsulant 50mg Tablet contains Topiramate, which works by restoring the balance of neural activity and reducing the spread of seizure activity in the brain. By controlling the electrical activity of the brain, Topsulant 50mg Tablet helps control seizures and relieves the symptoms of migraine.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Topsulant 50mg Tablet

Do not take more than the prescribed dose of Topsulant 50mg Tablet, as it may lead to an overdose. The symptoms of an overdose include drowsiness, blurred vision, speech disturbance, convulsions (fits), double vision, abnormal coordination, stupor (a state of insensibility or near-unconsciousness), stomach pain, low blood pressure, lethargy, mental impairment, depression, agitation, and dizziness. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Do not take Topsulant 50mg Tablet if you are allergic to any of its ingredients. Inform your doctor if you have ever had kidney problems (such as kidney stones or undergone dialysis), glaucoma (increased eye pressure), metabolic acidosis (excess acid in the blood), growth problems, breathing problems, diarrhoea, suicidal thoughts, mood disturbances, bone disorders (such as osteoporosis or osteomalacia), liver disease, or a blood disorder (such as acute porphyria). Do not stop taking Topsulant 50mg Tablet without consulting your doctor, as sudden withdrawal may lead to uncontrolled seizures. Topsulant 50mg Tablet is not recommended during pregnancy, as it may increase the risk of birth defects (like cleft palate and cleft lip) in the unborn baby. Topsulant 50mg Tablet may pass into breast milk, so consult your doctor to determine whether it is safe to breastfeed while taking Topsulant 50mg Tablet. If your baby is unusually sleepy, feeds poorly, or has diarrhoea, consult your doctor promptly. Avoid consuming alcohol while taking Topsulant 50mg Tablet, as it may worsen the side effects like dizziness and drowsiness. Topsulant 50mg Tablet may impair your vision, thinking, and motor skills; therefore, do not drive or operate machines until you know how this medication affects you.

Diet & Lifestyle Advise

  • Eat a balanced diet that consists of good fats, proteins, carbohydrates, vegetables, and fruit, which helps the body and brain work properly and keeps a person healthy and energetic.
  • Fatigue is one of the primary reasons that trigger seizures in the body, so sleeping properly can help relax the brain.
  • One should avoid the consumption of alcohol as it can trigger seizures in patients. Even one or two glasses can trigger epilepsy and worsen the side effects of Topsulant 50mg Tablet.
  • Maintain your happiness and avoid taking emotional stress, as it can trigger seizures. People who maintain healthy stress levels have reported that they have responded well to the medicine.

Habit Forming

No

Therapeutic Class

ANTICONVULSANT
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Alcohol

Caution

Avoid consuming alcohol while taking Topsulant 50mg Tablet, as it may worsen the side effects like dizziness and drowsiness.

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Pregnancy

Unsafe

Topsulant 50mg Tablet is not recommended during pregnancy, as it may increase the risk of birth defects (like cleft palate and cleft lip) in the unborn baby.

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Breast Feeding

Caution

Topsulant 50mg Tablet may pass into breast milk, so consult your doctor to determine whether it is safe to breastfeed while taking Topsulant 50mg Tablet. If your baby is unusually sleepy, feeds poorly, or has diarrhoea, consult your doctor promptly.

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Driving

Caution

Topsulant 50mg Tablet may impair your vision, thinking, and motor skills; therefore, do not drive or operate machines until you know how this medication affects you.

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Liver

Consult your doctor

Topsulant 50mg Tablet should be used with caution in patients with liver disease, as impaired liver function may reduce the medication's clearance. Therefore, the dosage may need to be reduced in patients with liver disease.

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Kidney

Consult your doctor

Topsulant 50mg Tablet should be used with caution in patients with kidney disease, as the dosage may need to be adjusted in patients with kidney impairment.

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Children

Safe if prescribed

Topsulant 50mg Tablet is safe to use in children above 2 years only if prescribed by the doctor.

Have a query?

FAQs

Topsulant 50mg Tablet is an anticonvulsant medication primarily used in the treatment of epilepsy (seizures/fits). It is also used in the prevention of migraine.

Topsulant 50mg Tablet works by restoring the balance of neural activity and reducing the spread of seizure activity in the brain. By controlling the electrical activity of the brain, Topsulant 50mg Tablet helps control seizures.

No, you should take rest after taking Topsulant 50mg Tablet. Topsulant 50mg Tablet may impair your vision, thinking, and motor skills, so avoid doing any task that requires mental alertness.

Topsulant 50mg Tablet acts by decreasing the spread of seizure activity in the brain. It also restores the normal balance of neurons, which in turn calms the brain. In epilepsy, cells present in the brain talk to each other by generating electric signals. When these cells fail to work properly or work faster than normal then it causes seizures. Topsulant 50mg Tablet slows down these electrical signals, thereby preventing or controlling seizures. While in migraine, Topsulant 50mg Tablet calms the overactive nerve cells in the brain that are responsible for triggering migraine attacks.

Yes, the use of Topsulant 50mg Tablet is safe for long-term use if suggested by the doctor.

Yes, Topsulant 50mg Tablet may affect the working of contraceptives that include the combined pill, vaginal ring, patches, progestogen-only contraceptive pill, and emergency contraception. Tell your doctor if you are using any type of contraceptives, as they may suggest using different types of contraceptives or combined hormonal contraceptives.

Generally, one should avoid consuming alcohol while taking Topsulant 50mg Tablet as it may make a person feel sleepy or tired and can cause seizures in some people with epilepsy.

Yes, studies have shown that Topsulant 50mg Tablet can cause hair loss (alopecia), but it is not a common side effect. If this happens, please consult your doctor and seek appropriate treatment.

Feeling sleepy is one of the most common side effects of Topsulant 50mg Tablet. It does not require medical attention, is usually mild and goes away over time. Consult the doctor if any of these side effects continue or worsen with time.

Do not stop taking Topsulant 50mg Tablet abruptly unless your doctor instructs you to. If you're using it to prevent migraines, your condition may worsen temporarily after you stop taking it. If you are using Topsulant 50mg Tablet for epilepsy, you may get seizures when you stop taking it. To prevent these withdrawal symptoms, your doctor may gradually reduce the dose of your Topsulant 50mg Tablet if required.

Take Topsulant 50mg Tablet for as long as prescribed by your doctor. The duration of treatment with Topsulant 50mg Tablet depends on the medical condition you are being treated for and your response to the treatment.

No, Topsulant 50mg Tablet is not intended to treat anxiety. It is mainly indicated for seizures.

The severe side effects caused by Topsulant 50mg Tablet include signs of glaucoma (blurred vision, difficulty seeing, and eye pain), kidney stones and a kidney infection (pain in your back, belly, or side, a burning sensation when you pee, or cloudy or smelly pee), metabolic acidosis (feeling sleepy, losing your appetite, and having an irregular heartbeat), and not sweating (especially in children). If this happens, consult your doctor immediately and seek medical attention.

Taking valproic acid when you are also taking Topsulant 50mg Tablet can cause your body temperature to drop to less than 95°F or 350C or cause tiredness, confusion, or coma. Taking these medicines may also raise the levels of ammonia in your blood. So, do not take these medications together. If you are required to, your doctor may guide you in taking them appropriately.

Topsulant 50mg Tablet is safe for children above two years of age only if prescribed by the doctor.

Weight loss and loss of appetite (anorexia) were two of the most commonly reported side effects. If you experience significant changes, seek medical advice from your healthcare professional.

The common side effects of Topsulant 50mg Tablet include dizziness, drowsiness, loss of appetite, nausea, tiredness, confusion, cognitive impairment, fever, flushing, and tingling in the legs and arms. Most of these side effects do not require medical attention and will gradually resolve on their own. If any of these side effects persist or worsen, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

No. 447, Poonamallee High Road, Aminjikarai, Chennai 600029.
Other Info - TOPS410

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