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Topzyme-D Tablet 10's

Topzyme-D Tablet 10's is used to treat pain and inflammation associated with conditions like osteoarthritis and rheumatoid arthritis. Additionally, it may also provide relief from toothache, ear pain, throat pain, muscle ache, and backache.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

BROMELAIN-90MG+DICLOFENAC-50MG+RUTOSIDE-100MG+TRYPSIN-48MG

Manufacturer/Marketer :

Somatico Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About Topzyme-D Tablet 10's

Topzyme-D Tablet 10's is used to treat pain and inflammation associated with osteoarthritis (joint pain, especially in the knees, hip, hands, neck, and lower back) and rheumatoid arthritis (joint pain, especially in the hands and feet). It may also provide relief from toothache, ear pain, throat pain, muscle ache, and backache.

Topzyme-D Tablet 10's contains Trypsin, Bromelain, Rutoside, and Diclofenac. Trypsin and Bromelain reduce pain and inflammation. Rutoside prevents swelling and inflammation. Diclofenac blocks the release of chemical substances that cause pain and inflammation.

Topzyme-D Tablet 10's may cause side effects such as nausea, vomiting, stomach pain, indigestion, heartburn, stomach upset, diarrhoea, and headache. These side effects are usually mild and temporary. However, if any of these side effects persist or worsen, consult a doctor immediately.

Consult your doctor if you are pregnant or breastfeeding. Topzyme-D Tablet 10's is not recommended for children below 12 years of age. Keep your doctor informed about your health conditions and medications to rule out any interactions.

Uses of Topzyme-D Tablet 10's

Topzyme-D Tablet 10's is used in the treatment of pain relief. The detailed uses of Topzyme-D Tablet 10's are as follows:

  • Relieve pain and inflammation: Topzyme-D Tablet 10's is primarily used to treat pain and swelling caused by injuries, surgeries, arthritis, and musculoskeletal conditions. Diclofenac acts as a non-steroidal anti-inflammatory drug (NSAID), while Trypsin and Bromelain are enzymes that enhance blood flow and reduce tissue inflammation.

Key Benefits

  • Provides effective pain relief in conditions like injury, arthritis, and post-surgery pain
  • Helps reduce inflammation and swelling
  • Promotes faster healing of tissues and wounds
  • Improves blood circulation at the affected area
  • Reduces bruising and edema (fluid accumulation)
  • Helps in recovery after trauma, sprains, and fractures
  • Supports breakdown of damaged proteins and dead tissue
  • Enhances overall mobility and comfort by reducing stiffness

Directions for Use

  • Topzyme-D Tablet 10's can be taken with or without food, as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow the whole Topzyme-D Tablet 10's with a glass of water.
  • Do not break, chew, or crush it.

How Topzyme-D Tablet 10's Works

Topzyme-D Tablet 10's contains Trypsin, Bromelain, Rutoside, and Diclofenac. • Trypsin and Bromelain reduce pain and inflammation by increasing the blood supply to the affected area and promoting healing. • Rutoside prevents swelling and inflammation by neutralising the chemicals that cause cell damage. • Diclofenac blocks the release of chemical substances that cause pain and inflammation.
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Alcohol

Consult your doctor

It is not known if alcohol interacts with Topzyme-D Tablet 10's. Please consult your doctor if you have any concerns.

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Pregnancy

Consult your doctor

If you are pregnant, please consult your doctor. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

Consult your doctor if you are breastfeeding. Your doctor will prescribe only if the benefits outweigh the risks.

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Driving

Caution

Topzyme-D Tablet 10's may cause blurred vision and dizziness. So, do not drive or operate heavy machinery unless you are alert.

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Liver

Caution

Topzyme-D Tablet 10's should be used with caution in patients with liver diseases. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Topzyme-D Tablet 10's should be used with caution in patients with kidney diseases. The dose may have to be adjusted by your doctor.

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Children

Unsafe

Topzyme-D Tablet 10's is not recommended for children below 12 years of age.

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Heart

Caution

Topzyme-D Tablet 10's should be used with caution in patients with heart problems. Inform your doctor about any heart-related conditions before taking Topzyme-D Tablet 10's.

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Geriatrics

Caution

Topzyme-D Tablet 10's should be given with caution in elderly patients due to an increased risk of side effects. It is important to inform your doctor before using it.

What if I have taken an overdose of Topzyme-D Tablet 10's

Take Topzyme-D Tablet 10's only as prescribed by the physician. Do not exceed the recommended dose, as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.

Diet & Lifestyle Advise

Diet

  • Eat light and balanced meals (fruits, vegetables, whole grains) to support healing and reduce stomach irritation.
  • Avoid spicy, oily, and acidic foods as they may increase the risk of gastric discomfort caused by diclofenac.
  • Stay well hydrated by drinking plenty of water to help reduce inflammation and support recovery.

Physical activity

  • Take adequate rest initially to allow healing of injured or inflamed tissues.
  • Start with gentle movements and light exercises to prevent stiffness and improve mobility.
  • Avoid heavy lifting and strenuous activities that may worsen pain or delay recovery.

Habits

  • Avoid smoking and alcohol as they can delay healing and increase side effects.
  • Maintain proper posture and body mechanics to reduce strain on affected areas.

Have a query?

How Soon It Starts Working

  • The time required for Topzyme-D Tablet 10's to start to work: Topzyme-D Tablet 10's shows its action within 30 to 60 minutes of administration.
  • The time for which the effects of Topzyme-D Tablet 10's last: Topzyme-D Tablet 10's effect lasts for 8 to 12 hours.

What if you forget to take Topzyme-D Tablet 10's

Take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and go back to your regular dosing schedule. Do not take a double dose to make up for your missed dose.

Storage

• Store in a cool and dry place away from sunlight.• Keep Topzyme-D Tablet 10's out of reach and sight of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Do not take Topzyme-D Tablet 10's if you are allergic to any of its contents.
  • Inform your doctor if you have/had high blood pressure, heart problems, high cholesterol, diabetes, asthma, angina, bowel problems, a blood-clotting disorder, a habit of smoking, or liver and kidney problems.
  • Consult your doctor if you are pregnant or breastfeeding.
  • Stop taking Topzyme-D Tablet 10's and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach, such as blood in stools.

verifiedApollotooltip

Drug-Drug Interactions: Inform your doctor if you are taking any of these medicines, as there may be an interaction.

  • Blood thinners (warfarin)
    • Potential effect: May increase the risk of bleeding
  • Water pills (furosemide)
    • Potential effect: May reduce the effectiveness of Topzyme-D Tablet 10's and cause kidney problems.
  • Anti-manic agent (Lithium)
    • Potential effect: May increase the effects of lithium, leading to unpleasant effects.
  • Painkillers (Ibuprofen, Aspirin)
    • Potential effect: May reduce the effect of Topzyme-D Tablet 10's in lowering blood pressure.

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Inform your doctor if you have a history of the following conditions before taking Topzyme-D Tablet 10's, as it may worsen your condition or cause complications.

  • Stomach ulcer or perforation
  • Bleeding problems
  • Bypass surgery
  • Heart attack
  • Blood circulation problems
  • Inflammation of the intestines
  • Anaemia
  • Heart, kidney or liver problems.

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Habit Forming

No

Therapeutic Class

[ANALGESICS]

FAQs

Topzyme-D Tablet 10's is used to relieve pain and inflammation associated with osteoarthritis (joint pain, especially in the knees, hip, hands, neck, and lower back) and rheumatoid arthritis (joint pain, especially in the hands and feet). It may also provide relief from toothache, ear pain, throat pain, muscle ache, and backache.
Topzyme-D Tablet 10's contains Trypsin, Bromelain, Rutoside, and Diclofenac. Trypsin and Bromelain reduce pain and inflammation by increasing the blood supply to the affected area and promoting healing. Rutoside prevents swelling and inflammation by neutralising the chemicals that cause cell damage. Diclofenac blocks the release of chemical substances that cause pain and inflammation.
Topzyme-D Tablet 10's is used to reduce and relieve pain and inflammation associated with osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. Arthritis is joint tenderness and swelling.
Avoid exceeding the dose and duration advised by the doctor. Topzyme-D Tablet 10's should not be taken for longer durations unless prescribed by your doctor.
If you miss a dose, take it as soon as you remember. However, if it is almost time for the scheduled dose, skip the missed dose and take the scheduled dose. Avoid taking a double dose.
Topzyme-D Tablet 10's may cause dizziness, as it is a common side effect. However, please consult a doctor if this side effect persists for more than a few days.
Topzyme-D Tablet 10's is contraindicated in individuals with known allergies to its ingredients, and those with high blood pressure, heart issues, diabetes, asthma, bowel problems, liver/kidney issues, or a smoking habit. Consult a doctor if pregnant or breastfeeding. Discontinue and seek medical advice if stomach pain or signs of bleeding occur.
Do not take higher than the recommended dose of Topzyme-D Tablet 10's as it can lead to increased side effects. Therefore, do not exceed the recommended dose. If your symptoms worsen, please consult your doctor.
Store Topzyme-D Tablet 10's at room temperature in a dry place as advised on the label. Protect from light. Keep it out of reach of children.
Topzyme-D Tablet 10's is typically used for short-term relief and can be stopped once pain and swelling subside. However, if your doctor has advised you to continue taking Topzyme-D Tablet 10's, continue taking it.
Yes, the use of Topzyme-D Tablet 10's can cause nausea and vomiting. Take it with food, milk or antacids to prevent nausea. If vomiting occurs, drink plenty of water or other fluids by taking small, frequent sips. However, if these side effects persist, consult your doctor.
You are recommended to contact a doctor before taking Topzyme-D Tablet 10's for dental pain or menstrual cramps, as it may not be suitable for all types of pain.
Topzyme-D Tablet 10's causes side effects such as nausea, dizziness, vomiting, stomach pain, indigestion, heartburn, headache, and diarrhoea. These do not require any medical treatment as they will gradually reduce over time. Consult a doctor if these side effects persist for more than a few days.
Topzyme-D Tablet 10's is contraindicated if you are allergic to any of its contents. Inform your doctor if you have a history of stomach ulcers or perforations, bleeding disorders, heart attack, bypass surgery, blood circulation problems, intestinal inflammation, anaemia, or kidney and liver issues.
Topzyme-D Tablet 10's is prescribed during pregnancy and breastfeeding only if your doctor believes the benefits outweigh the potential risks. The safety of Topzyme-D Tablet 10's during pregnancy or nursing has not been fully established. Therefore, consult your doctor before taking Topzyme-D Tablet 10's if you are pregnant or nursing. Do not self-medicate.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Electronic Medicines Compendium (EMC). Pil.2660 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026] Check here
  2. Shah D, Mital K The Role of Trypsin:Chymotrypsin in Tissue Repair. Adv Ther. 2018;35(1):31-42 Check here
  3. ScienceDirect ScienceDirect. [Accessed on 02 Apr. 2019] Check here
  4. Pavan R, Jain S, Shraddha, Kumar A. Properties and therapeutic application of bromelain: a review. NIH National Library of Medicine, National center for biotechnology information. Pubmed Central. December 2012. [Accessed on 4th July 2022] Check here
  5. Diclofenac Sodium. NIH National Library of Medicine, National center for biotechnology information. [Accessed on 4th July 2022] Check here
  6. Shah D, Mital K. The Role of Trypsin: Chymotrypsin in Tissue Repair. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. January 2018. [Accessed on 4th July 2022] Check here
  7. Swiss Caps GmbH. Electronic Medicines Compendium (EMC). [Revised in September 2020] [Accessed on 4th July 2022]Check here

Country of origin

India

Manufacturer/Marketer address

C-469, TTC, MIDC Pawane, Navi Mumbai 400703
Other Info - TOP0561

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