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About Tram Plus Tab
Tram Plus Tab belongs to a class of drugs called analgesics (pain killers) primarily used to treat moderate to severe pain. Pain is an unpleasant sensation caused by an injury or illness. Pain may be acute (short term) or chronic (long term). It can be general (overall body pains) or localized (pain in a specific area of the body).
Tram Plus Tab is a combination of two drugs, namely: Tramadol (opioid analgesic) and Acetaminophen (analgesic and antipyretic). Tramadol works by mimicking the action of endorphins (pain-reducing chemicals) in the brain and spinal cord. Thereby inhibits the transmission of pain signals from nerves to the brain. Also, it improves the effect of serotonin and noradrenaline (chemical messengers in the brain and spinal cord) and helps in relieving pain. Acetaminophen is an analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins that are responsible for pain and fever.
Take Tram Plus Tab as prescribed by your doctor. You are advised to take Tram Plus Tab for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience drowsiness, nausea, dizziness, headache, vomiting, dry mouth, constipation, excessive sweating, shaking, confusion or mood changes. Most of these side effects of Tram Plus Tab do not require medical attention and gradually resolve over time. However, if the side effects worsen or persist, please consult your doctor.
If you are allergic to Tram Plus Tab or any other medicines, please tell your doctor. Tram Plus Tab is not recommended for children below 12 years of age, as the safety and effectiveness were not established. Avoid taking Tram Plus Tab if you are pregnant as it may cause withdrawal symptoms in the newborn baby. Tram Plus Tab may be excreted in human milk. Please consult a doctor if you are breastfeeding. It is an offence to drive if Tram Plus Tab affects you. Therefore, avoid driving if you feel drowsy or dizzy after taking Tram Plus Tab. Avoid alcohol consumption with Tram Plus Tab as it may increase drowsiness.
Uses of Tram Plus Tab
Tram Plus Tab is used in the treatment of Moderate to severe pain. The detailed uses of Tram Plus Tab are as follows:

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Directions for Use
Key Benefits
Tram Plus Tab is a combination of two drugs: Tramadol and Acetaminophen to treat moderate to severe pain. Tramadol mimics the action of endorphins (pain-reducing chemicals) in the brain and spinal cord. Thereby inhibits the transmission of pain signals from nerves to brain. Also, it improves the effect of serotonin and noradrenaline (chemical messengers in the brain and spinal cord) and helps in relieving pain. Acetaminophen is an analgesic (relieves pain) and antipyretic (reduces fever) that inhibits the production of certain chemical messengers in the brain known as prostaglandins responsible for pain and fever.
How Tram Plus Tab Works
Storage
What if I have taken an overdose of Tram Plus Tab
Drug Warnings
If you are allergic to Tram Plus Tab or any other medicines, please tell your doctor. Tram Plus Tab is not recommended for children below 12 years of age, as the safety and effectiveness were not established. Avoid taking Tram Plus Tab if you are pregnant as it may cause withdrawal symptoms in the newborn baby. Tram Plus Tab may be excreted in human milk. Please consult a doctor if you are breastfeeding. If you have fits, asthma, severe lung problems, drug dependence, liver or kidney problems, inform your doctor before taking Tram Plus Tab. It is an offence to drive if Tram Plus Tab affects you. Therefore, avoid driving if you feel drowsy or dizzy after taking Tram Plus Tab. Avoid alcohol consumption with Tram Plus Tab as it may increase drowsiness. Do not take Tram Plus Tab if you are taking pain relievers, sleeping pills, or taking medicines such as linezolid, phenelzine, selegiline, rasagiline, isocarboxazid, tranylcypromine and methylene blue injection in the past 14 days. Inform your doctor immediately if you experience any sleep-related breathing problems such as sleep apnoea (breathing stops and starts repeatedly) while taking Tram Plus Tab.
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Alcohol
Safe if prescribed
Avoid consumption of alcohol with Tram Plus Tab as it may cause drowsiness.
Pregnancy
Consult your doctor
Tram Plus Tab is not recommended for pregnant women as it may cause withdrawal symptoms in the newborn baby. However, please consult your doctor if you are pregnant.
Breast Feeding
Consult your doctor
Tram Plus Tab may be excreted in breast milk and cause adverse effects in the baby. However, please consult a doctor if you are breastfeeding.
Driving
Safe if prescribed
Tram Plus Tab may cause dizziness or drowsiness in some people. It is an offence to drive if Tram Plus Tab affects you. Therefore, avoid driving if you feel drowsy or dizzy after taking Tram Plus Tab.
Liver
Consult your doctor
Take Tram Plus Tab with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required. Avoid taking Tram Plus Tab if you have severe liver insufficiency.
Kidney
Consult your doctor
Take Tram Plus Tab with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required. Avoid taking Tram Plus Tab if you have severe kidney insufficiency.
Children
Safe if prescribed
Tram Plus Tab is not recommended for children below 12 years of age, as the safety and effectiveness were not established.
Heart
Tram Plus Tab can be used in heart patients if prescribed by the physician. Please consult your physician if you have any concerns.
Geriatrics
Consult your doctor
Tram Plus Tab should be used under caution in geriatric patients. Please consult your physician.
Tram Plus Tab is used to treat moderate to severe pain.
Tram Plus Tab contains Tramadol and Acetaminophen. Tramadol is an opioid analgesic that works by mimicking the action of endorphins (pain-reducing chemicals) in the brain and spinal cord. Thereby, inhibits the transmission of pain signals from nerves to the brain. Also, it improves the effect of serotonin and noradrenaline (chemical messengers in the brain and spinal cord) and helps in relieving pain. Acetaminophen is an analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins that are responsible for pain and fever.
Tram Plus Tab may cause dry mouth as a common side effect. It is not necessary for everyone taking Tram Plus Tab to experience this side effect. However, drink plenty of water, suck on sugar candy or chew sugar-free gum to prevent such side effects while taking Tram Plus Tab. If the condition worsens or persist, please consult a doctor.
Tram Plus Tab should be used with caution in patients suffering from fits as it may worsen the condition. Therefore, it is recommended to inform your doctor if you ever had fits before taking Tram Plus Tab.
No, you are not recommended to take Tram Plus Tab with antidepressants (medicines used to treat depression), and antipsychotics (medicines used to treat bipolar disorder and psychosis) as co-administration of these medicines with Tram Plus Tab may increase the risk of fits. However, please consult a doctor before taking Tram Plus Tab with other medicines.
Tram Plus Tab may cause addiction, especially if taken for a prolonged time. Therefore, Tram Plus Tab should be given only for a short duration under strict medical supervision, particularly to patients who are susceptible to drug abuse. Take Tram Plus Tab only as a doctor advised as overuse or misuse of Tram Plus Tab can lead to overdose and cause severe adverse effects.
You are not recommended to take Tram Plus Tab with warfarin as co-administration of these two medicines may increase bleeding risk more easily. However, if you are supposed to use these medicines together, you are advised to contact your doctor so that the dose may be adjusted appropriately to use safely.
Tram Plus Tab may cause withdrawal symptoms such as difficulty sleeping, anxiety, nervousness, shaking, stomach or bowel disorders, or making you overactive when you stop taking Tram Plus Tab suddenly. Therefore, if you experience any difficulty while taking Tram Plus Tab, do not stop taking suddenly and consult your doctor so that the dose may be reduced gradually to avoid withdrawal symptoms.
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