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Tramasure-Plus Rf Tablet belongs to a class of drugs called analgesics (pain killers) primarily used to treat moderate to severe pain. Pain is an unpleasant sensation caused by an injury or illness. Pain may be acute (short term) or chronic (long term). It can be general (overall body pains) or localized (pain in a specific area of the body).
Tramasure-Plus Rf Tablet is a combination of two drugs, namely: Tramadol (opioid analgesic) and Acetaminophen (analgesic and antipyretic). Tramadol works by mimicking the action of endorphins (pain-reducing chemicals) in the brain and spinal cord. Thereby inhibits the transmission of pain signals from nerves to the brain. Also, it improves the effect of serotonin and noradrenaline (chemical messengers in the brain and spinal cord) and helps in relieving pain. Acetaminophen is an analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins that are responsible for pain and fever.
Take Tramasure-Plus Rf Tablet as prescribed by your doctor. You are advised to take Tramasure-Plus Rf Tablet for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience drowsiness, nausea, dizziness, headache, vomiting, dry mouth, constipation, excessive sweating, shaking, confusion or mood changes. Most of these side effects of Tramasure-Plus Rf Tablet do not require medical attention and gradually resolve over time. However, if the side effects worsen or persist, please consult your doctor.
If you are allergic to Tramasure-Plus Rf Tablet or any other medicines, please tell your doctor. Tramasure-Plus Rf Tablet is not recommended for children below 12 years of age, as the safety and effectiveness were not established. Avoid taking Tramasure-Plus Rf Tablet if you are pregnant as it may cause withdrawal symptoms in the newborn baby. Tramasure-Plus Rf Tablet may be excreted in human milk. Please consult a doctor if you are breastfeeding. It is an offence to drive if Tramasure-Plus Rf Tablet affects you. Therefore, avoid driving if you feel drowsy or dizzy after taking Tramasure-Plus Rf Tablet . Avoid alcohol consumption with Tramasure-Plus Rf Tablet as it may increase drowsiness.
Tramasure-Plus Rf Tablet is used in the treatment of Moderate to severe pain. The detailed uses of Tramasure-Plus Rf Tablet are as follows:
Tramasure-Plus Rf Tablet is a combination of two drugs: Tramadol and Acetaminophen to treat moderate to severe pain. Tramadol mimics the action of endorphins (pain-reducing chemicals) in the brain and spinal cord. Thereby inhibits the transmission of pain signals from nerves to brain. Also, it improves the effect of serotonin and noradrenaline (chemical messengers in the brain and spinal cord) and helps in relieving pain. Acetaminophen is an analgesic (relieves pain) and antipyretic (reduces fever) that inhibits the production of certain chemical messengers in the brain known as prostaglandins responsible for pain and fever.
Unsafe
Avoid consumption of alcohol with Tramasure-Plus Rf Tablet as it may cause drowsiness.
Unsafe
Tramasure-Plus Rf Tablet is not recommended for pregnant women as it may cause withdrawal symptoms in the newborn baby. However, please consult your doctor if you are pregnant.
Caution
Tramasure-Plus Rf Tablet may be excreted in breast milk and cause adverse effects in the baby. However, please consult a doctor if you are breastfeeding.
Unsafe
Tramasure-Plus Rf Tablet may cause dizziness or drowsiness in some people. It is an offence to drive if Tramasure-Plus Rf Tablet affects you. Therefore, avoid driving if you feel drowsy or dizzy after taking Tramasure-Plus Rf Tablet .
Caution
Take Tramasure-Plus Rf Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required. Avoid taking Tramasure-Plus Rf Tablet if you have severe liver insufficiency.
Caution
Take Tramasure-Plus Rf Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required. Avoid taking Tramasure-Plus Rf Tablet if you have severe kidney insufficiency.
Unsafe
Tramasure-Plus Rf Tablet is not recommended for children below 12 years of age, as the safety and effectiveness were not established.
Caution
Tramasure-Plus Rf Tablet can be used in heart patients if prescribed by the physician. Please consult your physician if you have any concerns.
Caution
Tramasure-Plus Rf Tablet should be used under caution in geriatric patients. Please consult your physician.

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If you are allergic to Tramasure-Plus Rf Tablet or any other medicines, please tell your doctor. Tramasure-Plus Rf Tablet is not recommended for children below 12 years of age, as the safety and effectiveness were not established. Avoid taking Tramasure-Plus Rf Tablet if you are pregnant as it may cause withdrawal symptoms in the newborn baby. Tramasure-Plus Rf Tablet may be excreted in human milk. Please consult a doctor if you are breastfeeding. If you have fits, asthma, severe lung problems, drug dependence, liver or kidney problems, inform your doctor before taking Tramasure-Plus Rf Tablet . It is an offence to drive if Tramasure-Plus Rf Tablet affects you. Therefore, avoid driving if you feel drowsy or dizzy after taking Tramasure-Plus Rf Tablet . Avoid alcohol consumption with Tramasure-Plus Rf Tablet as it may increase drowsiness. Do not take Tramasure-Plus Rf Tablet if you are taking pain relievers, sleeping pills, or taking medicines such as linezolid, phenelzine, selegiline, rasagiline, isocarboxazid, tranylcypromine and methylene blue injection in the past 14 days. Inform your doctor immediately if you experience any sleep-related breathing problems such as sleep apnoea (breathing stops and starts repeatedly) while taking Tramasure-Plus Rf Tablet .
Drug-Drug Interactions: Tramasure-Plus Rf Tablet may interact with anticonvulsants (carbamazepine, pregabalin), opioid pain killers (pentazocine, buprenorphine, nalbuphine, morphine), cough medication (codeine), muscle relaxant (baclofen), blood thinners (warfarin, phenprocoumon), antiemetic drugs (ondansetron, metoclopramide, domperidone), high cholesterol lowering medicine (cholestyramine), sedative-hypnotics (zolpidem), pain relievers (celecoxib), antidepressants (duloxetine, escitalopram), and anti-anxiety drugs (alprazolam).
Drug- Food Interactions: Avoid foods rich in carbohydrates, pectin including jellies, cabbage, Brussels sprouts and broccoli as Tramasure-Plus Rf Tablet may interact with these foods. Tramasure-Plus Rf Tablet may interact with grapefruit juice. Therefore, avoid intake of grapefruit juice with Tramasure-Plus Rf Tablet as it may increase Tramasure-Plus Rf Tablet levels in the body. Also, avoid alcohol consumption while taking Tramasure-Plus Rf Tablet as it may increase drowsiness.
Drug-Disease Interactions: If you have fits, asthma, severe lung problems, severe headaches associated with vomiting, drug dependence, liver or kidney problems or if you have recently suffered from shock or head injury, inform your doctor before taking Tramasure-Plus Rf Tablet .
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Tramasure-Plus Rf Tablet is used to treat moderate to severe pain.
Tramasure-Plus Rf Tablet contains Tramadol and Acetaminophen. Tramadol is an opioid analgesic that works by mimicking the action of endorphins (pain-reducing chemicals) in the brain and spinal cord. Thereby, inhibits the transmission of pain signals from nerves to the brain. Also, it improves the effect of serotonin and noradrenaline (chemical messengers in the brain and spinal cord) and helps in relieving pain. Acetaminophen is an analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins that are responsible for pain and fever.
Tramasure-Plus Rf Tablet may cause dry mouth as a common side effect. It is not necessary for everyone taking Tramasure-Plus Rf Tablet to experience this side effect. However, drink plenty of water, suck on sugar candy or chew sugar-free gum to prevent such side effects while taking Tramasure-Plus Rf Tablet . If the condition worsens or persist, please consult a doctor.
Tramasure-Plus Rf Tablet should be used with caution in patients suffering from fits as it may worsen the condition. Therefore, it is recommended to inform your doctor if you ever had fits before taking Tramasure-Plus Rf Tablet .
No, you are not recommended to take Tramasure-Plus Rf Tablet with antidepressants (medicines used to treat depression), and antipsychotics (medicines used to treat bipolar disorder and psychosis) as co-administration of these medicines with Tramasure-Plus Rf Tablet may increase the risk of fits. However, please consult a doctor before taking Tramasure-Plus Rf Tablet with other medicines.
Tramasure-Plus Rf Tablet may cause addiction, especially if taken for a prolonged time. Therefore, Tramasure-Plus Rf Tablet should be given only for a short duration under strict medical supervision, particularly to patients who are susceptible to drug abuse. Take Tramasure-Plus Rf Tablet only as a doctor advised as overuse or misuse of Tramasure-Plus Rf Tablet can lead to overdose and cause severe adverse effects.
You are not recommended to take Tramasure-Plus Rf Tablet with warfarin as co-administration of these two medicines may increase bleeding risk more easily. However, if you are supposed to use these medicines together, you are advised to contact your doctor so that the dose may be adjusted appropriately to use safely.
Tramasure-Plus Rf Tablet may cause withdrawal symptoms such as difficulty sleeping, anxiety, nervousness, shaking, stomach or bowel disorders, or making you overactive when you stop taking Tramasure-Plus Rf Tablet suddenly. Therefore, if you experience any difficulty while taking Tramasure-Plus Rf Tablet , do not stop taking suddenly and consult your doctor so that the dose may be reduced gradually to avoid withdrawal symptoms.
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