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compositionComposition:METHOTREXATE-2.5MG
prescription
Prescription Medicine
info
Trexo 2.5 Tablet 10's
Written By Santoshini Reddy G , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
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More about the Product

Composition :

METHOTREXATE-2.5MG

Manufacturer/Marketer :

Linux Laboratories Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Trexo 2.5 Tablet

Trexo 2.5 Tablet is a prescription medication used to manage severe autoimmune conditions like rheumatoid arthritis and severe psoriasis. It serves to calm an overactive immune system, helping to prevent joint damage and clear painful skin plaques. This medicine is typically prescribed when other standard therapies have not provided adequate relief.

To ensure your safety, Trexo 2.5 Tablet is typically taken only once a week on a very consistent schedule. You can take this oral medicine with or without food, but taking it with a full glass of water at the same time each week is highly recommended. Incorporating a nutrient-rich diet, staying well-hydrated, and completely avoiding alcohol are essential lifestyle adjustments that support the success of your treatment.

While using this medication, some people may experience common, mild side effects such as nausea, temporary hair thinning, or an upset stomach. However, you must consult your doctor immediately if you experience serious symptoms like a persistent cough, yellowing of the skin, or unusual bruising.

Before starting Trexo 2.5 Tablet , talk to your doctor if you have a history of liver disease, kidney problems, or lung conditions. Do not take this medicine if you are pregnant, planning to become pregnant, or breastfeeding, as it can cause severe harm to an unborn baby.

This medicine can interact with alcohol, raising the risk of liver damage, and with certain pain relievers, which can cause the drug to build up to unsafe levels. Pregnant women, breastfeeding mothers, and elderly individuals must consult their doctor or pharmacist before use, as they may require special dosing or monitoring.

Uses of Trexo 2.5 Tablet

Your doctor may prescribe this medicine to treat several conditions, including:

  • Severe Rheumatoid Arthritis: Trexo 2.5 Tablet helps reduce pain, swelling, and joint stiffness by calming the overactive immune response that attacks the joints.
  • Severe Psoriasis: It slows down the rapid growth of skin cells, helping to clear painful, scaly, and inflamed skin plaques when other therapies are ineffective.
  • Polyarticular Juvenile Idiopathic Arthritis: It helps manage joint pain and swelling in children with severe, active arthritis affecting multiple joints.
     

Key Benefits

By managing chronic inflammation, Trexo 2.5 Tablet helps improve daily physical function and comfort. The primary benefits of this treatment include:

  • Improved Joint Mobility: By reducing swelling and preventing joint damage, it helps you move more freely and perform everyday tasks with less pain.
  • Clearer Skin: For those dealing with severe skin plaques, it helps reduce scaling, redness, and discomfort, leading to healthier-looking skin.
  • Long-Term Disease Control: It acts as a disease-modifying treatment, meaning it doesn't just mask symptoms but actually helps slow down the progression of the condition over time.
     
Side effects of Trexo 2.5 Tablet
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Boost your immunity by including immune rich foods in your diet and always remember to stay hydrated.
  • Get sufficient sleep and manage stress which helps in improving white blood cell count.
  • Consult your doctor for an effective treatment to improve the blood cell count and get regular body check up to monitor changes in the count.
  • Try to prevent the factors that cause a decrease in white blood cells which may lead to impaired immunity.
Managing Medication-Triggered Erythema (Redness of the Skin or Skin redness): A Step-by-Step Guide:
  • Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication or providing guidance on managing your erythema symptoms.
  • Your doctor may recommend or prescribe certain medications to help alleviate symptoms.
  • Apply cool compresses or calamine lotion to the affected skin area to reduce redness and itching.
  • Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin hydrated.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
Here are the few steps for dealing with itching caused by drug use:
  • Report the itching to your doctor immediately; they may need to change your medication or dosage.
  • Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
  • Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
  • Try not to scratch, as this can worsen the itching and irritate your skin.
  • If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
  • Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.

Directions for Use

Always take this medicine exactly as prescribed by your healthcare provider. Because Trexo 2.5 Tablet is a potent medication, improper use can lead to serious health complications.

  • Check the schedule: This medication is typically taken once a week on the exact same day, not daily. Mark your calendar or set a weekly alarm.
  • Swallow the tablet whole: Take the tablet with a full glass of water. Do not crush, chew, or break the tablet.
  • Take with or without food: You can take your weekly dose with or without food, depending on what your doctor recommends.
  • Handle with care: Wash your hands thoroughly after handling the tablets, especially if you are a caregiver.

Always follow your doctor's exact instructions regarding your weekly dosing schedule.

 

How Trexo 2.5 Tablet Works

Trexo 2.5 Tablet contains methotrexate. It belongs to a class of medications known as antimetabolites or disease-modifying antirheumatic drugs (DMARDs). In conditions like rheumatoid arthritis and psoriasis, your immune system mistakenly attacks healthy tissues, causing rapid cell division and chronic inflammation. This medicine works by blocking a specific enzyme in the body that cells need to grow and multiply. By gently slowing down this cellular process, Trexo 2.5 Tablet calms the overactive immune system, reduces the rapid buildup of skin cells, and prevents inflammatory chemicals from damaging your joints and tissues.
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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Trexo 2.5 Tablet .

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Pregnancy

Unsafe

Trexo 2.5 Tablet may cause serious birth defects. It is not recommended to take Trexo 2.5 Tablet while you are pregnant.

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Breast Feeding

Unsafe

Trexo 2.5 Tablet passes into breast milk. Avoid breastfeeding whilst on treatment with Trexo 2.5 Tablet .

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Driving

Caution

Trexo 2.5 Tablet may cause dizziness and tiredness; do not drive or operate heavy machinery if you experience these symptoms.

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Liver

Caution

Do not take Trexo 2.5 Tablet if you have chronic liver disease. Please consult your doctor if you have liver impairment before taking Trexo 2.5 Tablet .

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Kidney

Caution

Please consult your doctor if you have kidney impairment before taking Trexo 2.5 Tablet .

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Children

Caution

Trexo 2.5 Tablet should be used with caution in children and only if prescribed by the doctor.

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Heart

Caution

Trexo 2.5 Tablet can be used in heart patients if prescribed by the physician. Please consult your physician if you have any concerns.

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Geriatrics

Safe if prescribed

Trexo 2.5 Tablet can be safely used in elderly patients with proper monitoring and individualised care.

What if I have taken an overdose of Trexo 2.5 Tablet

Do not take more than the prescribed dose of Trexo 2.5 Tablet as it may cause overdose leading to severe toxic reactions. The symptoms of overdose include unusual weakness, nausea, vomiting, easy bruising or bleeding, mouth sores, decreased urination, coughing up blood or vomit that looks like coffee grounds and black or bloody stools. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

  • Take Folic Acid as Prescribed: Your doctor will likely prescribe a folic acid (vitamin B9) supplement to take on the days you do not take Trexo 2.5 Tablet . This helps protect healthy cells and significantly reduces common side effects like mouth sores and nausea.
  • Avoid Alcohol Completely: Because this medication is processed by the liver, drinking alcohol while taking it drastically increases your risk of severe liver damage.
  • Protect Your Skin from the Sun: This medicine can make your skin highly sensitive to sunlight. Wear protective clothing, apply a high-SPF sunscreen daily, and avoid tanning beds.
  • Stay Well-Hydrated: Drink plenty of water throughout the day, especially on the day you take your medicine. Good hydration helps your kidneys flush the medication out of your system safely.
  • Practice Good Hand Hygiene: Since this medicine can temporarily lower your body's ability to fight infections, wash your hands frequently and try to avoid close contact with people who are actively sick.
     

Have a query?

How Soon It Starts Working

The time required for Trexo 2.5 Tablet to start to work: Trexo 2.5 Tablet ideally shows its action within 1 to 2 hours after administration.

The time for which the effects of Trexo 2.5 Tablet last: The effect of Trexo 2.5 Tablet lasts for 9 to 30 hours at a low dose and 24 to 45 hours at a high dose.

What if you forget to take Trexo 2.5 Tablet

If you miss a dose of Trexo 2.5 Tablet , take it as soon as you remember the next day or the day after. If your dose is more than 2 days late, contact your doctor for advice. Do not take a double dose to make up for the missed dose.

Storage

•Store this medication at controlled room temperature, ideally between 20°C and 25°C (68°F to 77°F).. •Keep the tablets in their original packaging to protect them from direct light and moisture, and do not store them in the bathroom cabinet.

Drug Warnings

  • Verify the Dose and Frequency: Always check your pill bottle to confirm you are taking the exact strength prescribed, and verify that you are taking it only once a week.
  • Avoid Daily Dosing Mistakes: Use a weekly pill planner or calendar check-off sheet to prevent accidentally taking this medication on consecutive days.
  • Monitor for Oral Ulcers: Regularly inspect your mouth and gums for painful sores, which can be an early sign of toxicity or folate deficiency.
  • Use Reliable Contraception: Ensure you are using highly effective birth control methods and confirm a negative pregnancy test before starting. Both male and female patients must maintain contraception during and for six months after treatment.
  • Keep All Lab Appointments: Never skip your scheduled blood tests, as they are your primary safety check for monitoring liver function and blood counts.
     

Drug-Drug Interactions

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Drug-Drug Interactions:

Inform your doctor if you are taking any of the following medicines, as they may interact.

  • NSAIDs (such as ibuprofen or naproxen): May increase the concentration of Trexo 2.5 Tablet in your blood to toxic levels by delaying its clearance through the kidneys.
  • Proton Pump Inhibitors (such as omeprazole or pantoprazole): May reduce the kidney's ability to eliminate the medicine, raising the risk of severe side effects.
  • Certain Antibiotics (such as trimethoprim/sulfamethoxazole): May increase the risk of severe bone marrow suppression and low blood cell counts.

Drug-Food Interactions:

  • Alcohol: May significantly increase the risk of liver damage and severe liver scarring.

Drug-Disease Interactions:

Inform your doctor if you have a history of the following conditions before taking it, as it may worsen your condition or cause complications.

  • Liver Disease: May cause severe, accelerated liver damage or liver failure in patients with pre-existing liver impairment.
  • Kidney Disease: May cause the medication to build up to dangerous, toxic levels in the body due to slower elimination.
  • Bone Marrow Suppression: May further decrease white blood cells, red blood cells, and platelets, increasing the risk of infection and bleeding.
  • Active Infections: May suppress your immune system further, making it harder for your body to fight off serious infections.
     
MethotrexateEtretinate
Critical
MethotrexateBenzylpenicillin
Severe

Drug-Drug Interactions

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MethotrexateEtretinate
Critical
How does the drug interact with Trexo 2.5 Tablet:
Co-administration of Etretinate with Trexo 2.5 Tablet may increase the risk or severity of liver problems.

How to manage the interaction:
Taking Etretinate with Trexo 2.5 Tablet is generally avoided as it can possibly result in an interaction, it can be taken if a doctor has advised it. Do not stop using any medications without talking to a doctor.
MethotrexateBenzylpenicillin
Severe
How does the drug interact with Trexo 2.5 Tablet:
Co-administration of Benzylpenicillin with Trexo 2.5 Tablet may increase the risk or severity of side effects.

How to manage the interaction:
Although there is an interaction, Trexo 2.5 Tablet can be taken with Benzylpenicillin if prescribed by the doctor. Consult the prescriber if you experience any symptoms such as fatigue, dizziness, fainting, unusual bleeding or bruising, fever, chills, sore throat, or body aches. Contact a doctor immediately. Do not stop using any medications without consulting to a doctor.
MethotrexateCladribine
Severe
How does the drug interact with Trexo 2.5 Tablet:
Co-administration of Trexo 2.5 Tablet with cladribine can increase the risk or severity of developing serious infections.

How to manage the interaction:
Although there is a possible interaction between cladribine and Trexo 2.5 Tablet, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, red or inflamed skin, and pain or burning during urination, Consult a doctor. Do not stop using any medications without consulting a doctor.
MethotrexatePhenylbutazone
Severe
How does the drug interact with Trexo 2.5 Tablet:
Coadministration of phenylbutazone with Trexo 2.5 Tablet may increase the levels and side effects of phenylbutazone.

How to manage the interaction:
Although there is a possible interaction between phenylbutazone and Trexo 2.5 Tablet, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as mouth ulcers or sores, vomiting, fever, chills, body aches, sore throat, muscle weakness, diarrhea, rash, loss of appetite, joint pain or swelling, yellow discoloration of skin and eyes, dark urine, breathing difficulty, dry cough, paleness, dizziness or fainting, unusual bruising or bleeding, seizures(fits), Consult a doctor. Do not stop using any medications without consulting a doctor.
MethotrexateOmeprazole
Severe
How does the drug interact with Trexo 2.5 Tablet:
Coadministration of omeprazole with Trexo 2.5 Tablet may increase the levels and side effects of omeprazole.

How to manage the interaction:
Although there is a possible interaction between omeprazole and Trexo 2.5 Tablet, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without consulting to a doctor.
MethotrexateLeflunomide
Severe
How does the drug interact with Trexo 2.5 Tablet:
Coadministration of leflunomide with Trexo 2.5 Tablet may increase the risk or severity of liver problems.

How to manage the interaction:
Although there is an interaction between leflunomide and Trexo 2.5 Tablet, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MethotrexateTenofovir disoproxil
Severe
How does the drug interact with Trexo 2.5 Tablet:
Coadministration of Tenofovir disoproxil with Trexo 2.5 Tablet may increase the levels and side effects of Tenofovir disoproxil.

How to manage the interaction:
Although there is a possible interaction between tenofovir disoproxil and Trexo 2.5 Tablet, you can take these medicines when prescribed by your doctor. However, if you experience any symptoms such as vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, breathing difficulty, or dizziness, consult your doctor. Do not stop using any medications without consulting a doctor.
MethotrexateEsomeprazole
Severe
How does the drug interact with Trexo 2.5 Tablet:
Co-administration of Trexo 2.5 Tablet and esomeprazole can increase the blood levels and side effects of Trexo 2.5 Tablet.

How to manage the interaction:
Although taking Esomeprazole with Trexo 2.5 Tablet can result in an interaction, they can be taken together if prescribed by a doctor. However, contact your doctor if you experience headache, dizziness, nausea and vomiting. Do not discontinue any medications without consulting a doctor.
MethotrexateAmoxicillin
Severe
How does the drug interact with Trexo 2.5 Tablet:
Co-administration of Trexo 2.5 Tablet with amoxicillin can increase the levels and side effects of Trexo 2.5 Tablet.

How to manage the interaction:
Although there is a possible interaction between Trexo 2.5 Tablet and amoxicillin, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as tiredness, dizziness, fainting, unusual bleeding or bruising, chills, fever, sore throat, body pains. Consult a doctor immediately. Do not stop using medications without a doctor's advice.
MethotrexatePantoprazole
Severe
How does the drug interact with Trexo 2.5 Tablet:
Co-administration of Trexo 2.5 Tablet with pantoprazole can increase the levels and side effects of Trexo 2.5 Tablet.

How to manage the interaction:
Although there is a possible interaction between pantoprazole and Trexo 2.5 Tablet, you can take these medicines together if prescribed by a doctor. However, if you experience any symptoms such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, tiredness, weakness, or dizziness, consult a doctor. Do not stop using any medications without consulting a doctor.

Drug-Food Interactions

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METHOTREXATE-2.5MGCaffeine containing foods/drinks
Moderate

Drug-Food Interactions

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METHOTREXATE-2.5MGCaffeine containing foods/drinks
Moderate
Common Foods to Avoid:
Cocoa, Coffee, Dark Chocolate, Energy Drinks With Caffeine, Green Tea, Kola Nut, Tea, Tiramisu

How to manage the interaction:
Caffeine may reduce the effectiveness of Trexo 2.5 Tablet. Avoid taking caffeine while taking Trexo 2.5 Tablet. This can increase the risk or severity of side effects.

All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[IMMUNOSUPPRESSANTS, ANTIMETABOLITES]

FAQs

Trexo 2.5 Tablet is used to treat active rheumatoid arthritis, including polyarticular juvenile rheumatoid arthritis, severe psoriasis, and severe psoriatic arthritis. It is also used alone or in combination with other medicines to treat breast cancer, lung cancer, head and neck cancer, mycosis fungoides (a type of blood cancer), and advanced-stage non-Hodgkin lymphomas (cancer that starts in the lymphatic system).

Trexo 2.5 Tablet acts as an immunosuppressant, which helps in reducing inflammation and preventing joint stiffness, thereby providing relief from rheumatoid arthritis.

Trexo 2.5 Tablet works by suppressing the overactive immune system that is responsible for causing psoriasis. Trexo 2.5 Tablet interferes with the synthesis of genetic material (DNA) and the growth of cells that multiply faster than usual, thereby helping in treating psoriasis and psoriatic arthritis.

Diarrhoea might be a side-effect of Trexo 2.5 Tablet . Stop taking Trexo 2.5 Tablet and consult your doctor if you have diarrhoea. Do not take anti-diarrheal medicine on your own.

Trexo 2.5 Tablet can affect egg and sperm production and could lead to birth defects. Women of child-bearing potential and men using Trexo 2.5 Tablet must use effective contraception while on treatment with Trexo 2.5 Tablet and for at least six months after stopping the treatment. Trexo 2.5 Tablet can lead to infertility. Therefore, male patients are advised to talk with their doctor regarding the possibility of sperm preservation before starting the treatment with Trexo 2.5 Tablet .

Yes. Trexo 2.5 Tablet may lower the number of white blood cells (leukopenia), making you more susceptible to infections. Contact your doctor if you develop symptoms such as fever, sore throat, breathlessness, jaundice, unusual bleeding, or unexplained bruising.

Yes. Trexo 2.5 Tablet may cause inflammation of the mouth lining (mucositis), leading to mouth sores or ulcers. Contact your doctor if you develop painful mouth ulcers. Folic acid supplementation may help reduce this side effect.

Before using Trexo 2.5 Tablet , you should inform your doctor about your medical history, including any ongoing medicines, to avoid potential interactions and minimise side effects.

Trexo 2.5 Tablet is not a painkiller. It is an anti-metabolite.

Trexo 2.5 Tablet is not suitable for some people. To ensure your safety, tell your doctor about all your medical conditions and medications before taking it. Based on your medical condition, your doctor will advise you whether to take it.

Common side effects of Trexo 2.5 Tablet may include nausea, vomiting, diarrhoea, unusual fatigue, dizziness, headache, loss of appetite, lowered resistance to infections, tingling sensation, leukopenia (decreased number of white blood cells), and soreness of mouth and lips. If you experience these side effects persistently, you are advised to talk to your doctor.

Yes, you can consume. However, you should avoid intake of unpasteurized milk, and soft cheeses are recommended.

It's also best to avoid too much caffeine, which is found in coffee, tea, cola, energy drinks, and chocolate. Caffeine can prevent Trexo 2.5 Tablet from working as it should.

Drinking alcohol is generally acceptable if you are taking Trexo 2.5 Tablet for the long-term treatment of an inflammatory disorder at a low weekly dose (25 mg or less). If you take large dosages of methotrexate, consult your physician and seek medical advice.

Trexo 2.5 Tablet may increase your risk of liver and lung problems, especially if you take a high dose. Your doctor, however, will closely monitor you while you are taking Trexo 2.5 Tablet . Routine check-ups will reveal any concerns or issues. If you have any concerns about taking Trexo 2.5 Tablet , consult your doctor.

Absolutely not. Trexo 2.5 Tablet is harmful to a fetus and can cause congenital mutations. Women should wait 90 days after finishing methotrexate before getting pregnant. Men should also wait 90 days before attempting to conceive because methotrexate may impair sperm (sperm formation takes 90 days).

Trexo 2.5 Tablet may somewhat reduce your body's response to immunizations, making them less effective than if you were not taking it. It is usually recommended that you be up to date on your immunizations before beginning Trexo 2.5 Tablet . If you have any concerns, please seek medical advice from your healthcare professional.

Taking more than the recommended dosage does not provide additional pain relief and can increase the risk of adverse effects.

Take the missed dose as soon as you remember, unless it's almost time for your next dose. In this case, skip the missed dose and take your next dose at the regular time. Never take a double dose to make up for a missed one.

Trexo 2.5 Tablet should be used with caution in children and only if prescribed by the doctor.

Trexo 2.5 Tablet may cause dizziness and tiredness; do not drive or operate heavy machinery if you experience these symptoms.

This medicine is highly potent and works by slowing down cell growth. Taking it daily instead of weekly can lead to severe, life-threatening complications, including severe bone marrow suppression and organ damage. Always stick strictly to your once-weekly schedule. Talk to your doctor if you have questions about your routine.

No, you should avoid alcohol completely. Both alcohol and this medication are processed by the liver, and combining them significantly increases your risk of serious liver damage and scarring. Talk to your doctor for guidance.

Trexo 2.5 Tablet can cause serious birth defects and pregnancy loss. Both men and women should use effective contraception during treatment and for at least 6 months after the last dose (follow your doctor's advice regarding the exact duration). If you or your partner

Folic acid helps protect healthy cells from some of the side effects of Trexo 2.5 Tablet . It may reduce the risk of mouth ulcers, nausea, diarrhoea, fatigue, and other adverse effects without reducing treatment effectiveness.

Trexo 2.5 Tablet is a slow-acting medicine. Many people notice improvement within 6–8 weeks, but it may take 3–6 months to experience the full benefits of treatment.

You should avoid taking nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen or naproxen without consulting your doctor first. These pain relievers can slow down the clearance of the medicine from your body, increasing the risk of serious side effects. Talk to your doctor or pharmacist for safe pain management alternatives.

Some patients experience mild, temporary hair thinning while taking this medication. Complete hair loss is rare at the low doses used for arthritis and psoriasis. Often, taking your prescribed folic acid helps reduce this side effect. Talk to your doctor if you notice significant hair changes.

Regular blood tests are essential to monitor your blood cell counts, liver function, and kidney function. Some serious side effects may occur without obvious symptoms, so routine monitoring helps ensure the medicine remains safe and effective.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. U.S. Food and Drug Administration (FDA). 011719S117Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026] Check here
  2. National Health Service (NHS). Ibd Methotrexate Leaflet - NHS Medicines Reference Guide. London, UK: NHS; 2025. [Accessed on 02 Jun. 2026] Check here
  3. Drugs.com Clinical Review Team. Methotrexate Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026] Check here
  4. MedlinePlus. A682019 Patient Information Monograph. Bethesda, MD: U.S. National Library of Medicine (NLM); 2025. [Accessed on 02 Jun. 2026] Check here
  5. Methotrexate [Prescribing Information]. 2020. [Accessed on 19 Apr. 2023] Check here
  6. Methotrexate [Prescribing Information]. 2023. [Accessed on 26 Feb. 2025] Check here
  7. Webmed.methotrexate. 2025 [Accessed on 5th Dec 2025]Check here

Country of origin

India

Manufacturer/Marketer address

No.9, Main Road, Ganapathy Nagar, Kovilambakkam, Chennai 600129.
Other Info - TRE0398

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