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  3. Trimium Transhaler

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Trimium Transhaler, Pack of 1 TRANSHALER
Trimium Transhaler, Pack of 1 TRANSHALER
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Trimium Transhaler is used to treat asthma symptoms and chronic obstructive pulmonary diseases (COPD). It relaxes the airway muscles and widen the airways. Thus, makes breathing easier for asthma and COPD patients. It may cause side effects such as fungal infection in the mouth, vomiting, nausea, headache, sore throat, hoarse voice, upper respiratory tract infection, flu, cough, Musculoskeletal (bone, muscle, or joint) pain, increased heart rate, and trembling.

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Composition :

CICLESONIDE-200MCG + FORMOTEROL-6MCG + TIOTROPIUM-9MCG

Manufacturer/Marketer :

Lupin Ltd

Consume Type :

INHALATION

Return Policy :

Not Returnable

Expires on or after :

About Trimium Transhaler

Trimium Transhaler belongs to the class 'respiratory stimulants', which are primarily used to treat asthma symptoms and chronic obstructive pulmonary diseases (COPD). Asthma is a chronic (long-term) respiratory condition in which airways narrow, swell, and produce extra mucus, leading to difficulty breathing. COPD is a group of lung diseases with emphysema (shortness of breath) and chronic bronchitis (inflammation of the lining of bronchial tubes).

Trimium Transhaler is a combination of three drugs: Tiotropium (anti-cholinergic), Formoterol (LABA - long-acting beta-agonists or bronchodilator), and ciclesonide (corticosteroid). Tiotropium is an anti-cholinergic, and formoterol is a bronchodilator. Both medicines work by relaxing the airway muscles and widen the airways. These medicines together making it easier for asthma and COPD patients to breathe. Whereas ciclesonide is a corticosteroid, it acts by stopping the release of certain natural substances in the body that are responsible for inflammation of the airways.

Your doctor will recommend how often you take Trimium Transhaler based on your medical condition. Some people may experience side effects like a fungal infection in the mouth, vomiting, nausea, headache, sore throat, hoarse voice, upper respiratory tract infection, flu, cough, Musculoskeletal (bone, muscle, or joint) pain, increased heart rate, and trembling. Most of these side effects of Trimium Transhaler do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, stop the medicine and consult your doctor.

If you are allergic to lactose (a form of sugar) or have lactose intolerance, Trimium Transhaler, or any other ingredients, please tell your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Trimium Transhaler. Trimium Transhaler is not recommended for children below 6 years of age. If your breathing worsens or you often wake up at night with asthma, experience chest tightness in the morning, or last longer than usual, please consult a doctor immediately. These might be signs indicating that your asthma is not controlled properly and requires an alternate or additional treatment. Regular monitoring of potassium levels is recommended while taking Trimium Transhaler as it may cause low potassium levels in the blood. If you have high blood pressure, diabetes, hypokalaemia (low potassium levels in the blood), glaucoma, cataracts, osteoporosis (weak bones), fits, immune system problems, chickenpox, measles, thyroid, lung, heart, liver, or adrenal gland problems, tuberculosis inform your doctor before taking Trimium Transhaler. Trimium Transhaler should be used with caution in patients with narrow-angle glaucoma, prostatic hyperplasia, or bladder neck obstruction.

Uses of Trimium Transhaler

Trimium Transhaler is used in the treatment of Asthma, Chronic obstructive pulmonary disease (COPD). The detailed uses of Trimium Transhaler are as follows: <br/>• Asthma management: Trimium Transhaler is widely prescribed for asthma patients to reduce inflammation and prevent asthma attacks. It works by relaxing airway muscles, eases breathing and provides effective relief.<br/>• COPD treatment: Trimium Transhaler is highly effective in managing chronic obstructive pulmonary disease (COPD), a progressive lung condition. It helps alleviate symptoms like breathlessness and wheezing, ensuring better respiratory function.<br/>• Inflammation control: Trimium Transhaler is effective in reducing swelling in the airways, which makes it easier for individuals with respiratory conditions to breathe.<br/>

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Directions for Use

  • It is recommended to take Trimium Transhaler twice a day or as advised by your doctor.
  • It is a capsule with powdered medication which is placed in rotahaler/transhaler, a plastic inhalation device that releases the medication when you breathe. The capsule should be placed at the base of the rotahaler/transhaler, and completely twist the mouthpiece until you hear a click sound. Then, breathe in through the mouthpiece deeply and hold your breath for 10 seconds. Remove the device and breathe out normally.
  • Remove the inhaler and hold your breath for a few seconds, then breathe out slowly.
  • Rinse your mouth with water and spit it out after using it to avoid fungal infections in the mouth and throat.
  • It is for inhalation only. Do not swallow the capsule.

Medicinal Benefits

Trimium Transhaler is a combination of three drugs: Tiotropium (anti-cholinergic), Formoterol (LABA - long-acting beta-agonists or bronchodilator), and ciclesonide (corticosteroid). Tiotropium is an anti-cholinergic, and formoterol is a bronchodilator. Both medicines work by relaxing the airway muscles and widen the airways. These medicines together making it easier for asthma and COPD patients to breathe. Whereas ciclesonide is a corticosteroid, it acts by stopping the release of certain natural substances in the body that are responsible for inflammation of the airways.

How Trimium Transhaler Works

Trimium Transhaler is a combination of three drugs: Tiotropium (anti-cholinergic), Formoterol (LABA - long-acting beta-agonist or bronchodilator), and ciclesonide (corticosteroid). Tiotropium is an anticholinergic, and formoterol is a bronchodilator. Both medicines work by relaxing the airway muscles and widening the airways. These medicines together make it easier for asthma and COPD patients to breathe. Whereas ciclesonide is a corticosteroid, it acts by stopping the release of certain natural substances in the body that are responsible for inflammation of the airways.

Storage

Keep Trimium Transhaler out of the sight and reach of children.
Side effects of Trimium Transhaler
Here are the steps to manage the medication-triggered Upper respiratory tract infection:
  • Inform your doctor about the symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids to help loosen and clear mucus from your nose, throat, and airways.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.
Here are the steps to Dry Mouth (xerostomia) caused by medication:
  • Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
  • Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
  • Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
  • Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
  • Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.
  • Focus on eating nutrient-rich foods such as citrus fruits, spinach, ginger, garlic, turmeric, and fermented foods to improve immunity and general health.
  • Drink plenty of water to stay hydrated, and think about taking probiotics, zinc, vitamin C, and vitamin D supplements.
  • Adopt healthful practices such as leading a balanced lifestyle and remaining at home when necessary.
Here are the steps to manage the medication-triggered Sinusitis (Sinus infection or Inflammation Of Sinuses):
  • Consult your doctor if you experience symptoms of sinusitis, such as nasal congestion, facial pain, or headaches, which may be triggered by your medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your sinusitis symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • If your doctor advises, you can use nasal decongestants or saline nasal sprays to help relieve nasal congestion and sinus pressure.
  • To help your body recover, get plenty of rest, stay hydrated, and engage in stress-reducing activities. If your symptoms persist or worsen, consult your doctor for further guidance.
  • To keep your vocal cords lubricated and hydrated, drink lots of water.
  • Suck on ice chips, popsicles, or lozenges to clear your throat and reduce hoarseness.
  • Your voice cords may be soothed and healed by honey's antibacterial and anti-inflammatory properties.
  • Gargle with salt water.
  • Using a steam humidifier or inhaling steam might help minimize hoarseness and release mucus.
  • Rest well; get enough sleep. This helps the body fight infection.
  • Keep yourself hydrated by drinking enough water and other fluids.
  • Wash your hands often and avoid touching your eyes, mouth or nose.
  • Wear a mask whilst going out.
  • Warm steam or a hot shower may help with nose secretions.
  • Avoid contact with others to prevent contamination.
Here are the steps to manage the medication-triggered Common Cold:
  • Inform your doctor about the common cold symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Drink plenty of fluids, such as warm water or soup, to help thin out mucus.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.

What if I have taken an overdose of Trimium Transhaler

Do not use Trimium Transhaler in more doses or more often than prescribed. If you have any unusual signs or symptoms, please consult a doctor immediately.

Drug Warnings

If you are allergic to lactose (a form of sugar) or have lactose intolerance, Trimium Transhaler, or any other ingredients, please tell your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Trimium Transhaler. Trimium Transhaler is not recommended for children below 6 years of age. If your breathing worsens or you often wake up at night with asthma, experience chest tightness in the morning, or last longer than usual, please consult a doctor immediately. These might be signs indicating that your asthma is not controlled properly and requires an alternate or additional treatment. Regular monitoring of potassium levels is recommended while taking Trimium Transhaler as it may cause low potassium levels in the blood. If you have high blood pressure, diabetes, hypokalaemia (low potassium levels in the blood), glaucoma, cataracts, osteoporosis (weak bones), epilepsy, immune system problems, chickenpox, measles, thyroid, lung, heart, liver, or adrenal gland problems, tuberculosis inform your doctor before taking Trimium Transhaler. Trimium Transhaler should be used with caution in patients with narrow-angle glaucoma, prostatic hyperplasia, or bladder neck obstruction.

Drug-Drug Interactions

verifiedApollotooltip
CiclesonideDesmopressin
Critical
FormoterolTimolol
Severe

Drug-Drug Interactions

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CiclesonideDesmopressin
Critical
How does the drug interact with Trimium Transhaler:
Co-administration of Bumetanide and Desmopressin may increase the risk of hyponatremia (low levels of salt in the blood).

How to manage the interaction:
If you have to use Desmopressin and Trimium Transhaler together, a doctor may adjust the dose or monitor you more frequently to safely use both medications. However, if you experience loss of appetite, headache, nausea, vomiting, lethargy (very tired), irritability, difficulty concentrating, weakness, unsteadiness, memory impairment, confusion, muscle spasm, decreased urination, and/or sudden weight gain, contact your doctor immediately as these may be symptoms of water intoxication (water poisoning) and hyponatremia (low levels of salt in the blood). Do not discontinue the medication without consulting a doctor.
FormoterolTimolol
Severe
How does the drug interact with Trimium Transhaler:
Taking timolol with Trimium Transhaler could reduce the benefits of both medications because they have opposite effects on the body.

How to manage the interaction:
Although taking Trimium Transhaler and timolol together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience any unusual symptoms, contact your doctor immediately. Do not stop using any medications without talking to your doctor.
FormoterolPropranolol
Severe
How does the drug interact with Trimium Transhaler:
Coadministration of propranolol with Trimium Transhaler can reduce the effects of both medications.

How to manage the interaction:
Although taking propranolol and Trimium Transhaler together can result in an interaction, it can be taken if your doctor has prescribed it. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
FormoterolRibociclib
Severe
How does the drug interact with Trimium Transhaler:
Taking ribociclib together with Trimium Transhaler can increase the risk of an irregular heart rhythm

How to manage the interaction:
Co-administration of Trimium Transhaler with Ribociclib can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, or shortness of breath, contact your doctor right away. Do not stop using any medications without first talking to your doctor.
FormoterolCarteolol
Severe
How does the drug interact with Trimium Transhaler:
Taking carteolol with Trimium Transhaler can reduce the effects of both drugs.

How to manage the interaction:
Although there is an interaction between Carteolol and Trimium Transhaler, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
FormoterolEpinephrine
Severe
How does the drug interact with Trimium Transhaler:
Using epinephrine together with Trimium Transhaler may increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Trimium Transhaler and Epinephrine together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
FormoterolLevobunolol
Severe
How does the drug interact with Trimium Transhaler:
Using Trimium Transhaler together with levobunolol can reduce the effects of both medications.

How to manage the interaction:
Taking Trimium Transhaler with Levobunolol together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
FormoterolSotalol
Severe
How does the drug interact with Trimium Transhaler:
Taking sotalol with Trimium Transhaler could reduce the benefits of both medications because they have opposite effects on the body.

How to manage the interaction:
Although there is an interaction between Sotalol and Trimium Transhaler, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
FormoterolCarvedilol
Severe
How does the drug interact with Trimium Transhaler:
Using Trimium Transhaler and Carvedilol together may reduce the effects of both medications.

How to manage the interaction:
Although there is an interaction between Trimium Transhaler and Carvedilol, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
FormoterolMetipranolol
Severe
How does the drug interact with Trimium Transhaler:
Using Trimium Transhaler together with metipranolol can reduce the effects of both medications.

How to manage the interaction:
Although there is an interaction between Trimium Transhaler and metipranolol, they can be taken together if prescribed by your doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to strengthen your breathing muscles and boost your immune system.
  • Avoid foods such as cabbage, beans, garlic, onions, shrimp, pickled food, dried fruits, fried foods, carbonated drinks, wine, bottled lemon, and lime juice as it may worsen asthma symptoms.
  • Do meditation, deep breathing, regular exercise, and try progressive muscle relaxation techniques to get relief from stress and reduce the risk of an asthma attack.
  • Quit smoking as it may reduce the effectiveness of the Trimium Transhaler and irritate the lungs worsening breathing problems.
  • Learning breathing exercises will help you move more air in and out of your lungs.
  • Limit alcohol intake.

Habit Forming

No

Therapeutic Class

RESPIRATORY STIMULANTS
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Alcohol

Consult your doctor

The interaction of Trimium Transhaler with alcohol is unknown. Please consult a doctor before consuming alcohol with Trimium Transhaler.

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Pregnancy

Consult your doctor

The safety of Trimium Transhaler in pregnant women is unknown. Therefore, it is given to pregnant women only if the doctor thinks the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

It is unknown whether Trimium Transhaler is excreted in human milk. It is given to breastfeeding mothers only if the doctor thinks benefits are greater than risks.

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Driving

Safe if prescribed

Trimium Transhaler usually does not affect your ability to drive or operate machinery.

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Liver

Caution

Use Trimium Transhaler with caution, especially if you have a history of liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Consult your doctor

If you have any concerns regarding the use of Trimium Transhaler in patients with kidney problems, please consult your doctor.

bannner image

Children

Caution

Trimium Transhaler is not recommended for children below 6 years as the safety and effectiveness have not been established. However, please consult a doctor before giving Trimium Transhaler to children.

FAQs

Trimium Transhaler is used to treat asthma symptoms and chronic obstructive pulmonary diseases (COPD).

Yes, Trimium Transhaler may cause fungal infection in the mouth (oral thrush) is a common side effect. It is not necessary for everyone taking Trimium Transhaler to experience this side effect. However, to avoid such side effects, brush your teeth or rinse your mouth with water after using Trimium Transhaler every time.

You are not recommended to stop taking Trimium Transhaler without consulting your doctor as it may worsen the condition or cause recurring symptoms. Therefore, take Trimium Transhaler for as long as your doctor has prescribed it.

People with heart problems (including high blood pressure, chest pain, fast heartbeat, fits (seizures), thyroid problems, diabetes, immune system problem, weak bones or osteoporosis, eye problems (glaucoma, cataracts), and liver problems should consult a doctor before using Trimium Transhaler.

Yes, Trimium Transhaler causes dry mouth/ dry throat as a side effect. Frequent mouth rinses, good oral hygiene, increased water intake, and sugarless candy may help to relieve dry mouth/dry throat.

Trimium Transhaler should be used with caution in osteoporosis (low bone density resulting in weak and brittle bones) patients as it may worsen the condition. Therefore, inform your doctor if you have osteoporosis before taking Trimium Transhaler so that the dose may be adjusted or an alternate medicine may be prescribed.

Trimium Transhaler is a combination of three drugs: Tiotropium (anti-cholinergic), Formoterol (LABA - long-acting beta-agonists or bronchodilator), and ciclesonide (corticosteroid). Tiotropium is an anti-cholinergic, and formoterol is a bronchodilator. Both medicines work by relaxing the airway muscles and widen the airways. These medicines together making it easier for asthma and COPD patients to breathe. Whereas ciclesonide is a corticosteroid it acts by stopping the release of certain natural substances in the body that are responsible for inflammation of the airways.

Country of origin

India

Manufacturer/Marketer address

Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India Country of Origin: India
Other Info - TRI0967

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 6:45 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.ciplamed.com/content/triohale-rotacaps
  2. https://www.drugssquare.com/asthma-drugs/tiotropium-formoterol-ciclesonide-triohale-rotacaps/
  3. https://www.webmd.com/drugs/2/drug-89061-1655/tiotropium-bromide-inhalation/tiotropium-inhalation/details
  4. https://6degrepharma.tradeindia.com/ciclesonide-and-formoterol-and-tiotropium-rotacap-7668323.html

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