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Trioday 400 Tablet is used to treat HIV infection. It works by inhibiting the reverse transcriptase enzyme, which is essential for the reproduction of the virus. In some cases, this medicine may cause side effects such as nausea, headache, dizziness, weakness, tiredness, and diarrhoea. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

EFAVIRENZ-400MG+LAMIVUDINE-300MG+TENOFOVIR DISOPROXIL-245MG

Manufacturer/Marketer :

Cipla Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Trioday 400 Tablet

Trioday 400 Tablet is a prescription tablet used to treat Human Immunodeficiency Virus type 1 (HIV-1) infection in adults and eligible children. It combines three antiviral medicines into a single daily pill to help control the virus and protect your immune system. By keeping the viral load low, Trioday 400 Tablet helps prevent the virus from multiplying and damaging your body's natural defences.

For this medicine to work effectively, you must take Trioday 400 Tablet consistently every single day at the same time. It is highly recommended to take Trioday 400 Tablet on an empty stomach, preferably at bedtime, because taking it with food can increase the absorption of one of its ingredients and lead to more side effects. Alongside your medication, eating a balanced diet, staying hydrated, and avoiding recreational substances can significantly support your immune health.

While taking Trioday 400 Tablet , you may experience mild, temporary side effects such as dizziness, trouble sleeping, or mild headaches, which often improve after a few weeks. However, you must contact your doctor immediately if you experience serious side effects, such as severe skin rashes, mood changes, yellowing of your skin or eyes, or severe stomach pain.

Before starting Trioday 400 Tablet , talk to your doctor if you have a history of liver disease, kidney problems, bone thinning, or mental health conditions like depression. Do not take this if you are allergic to any of its active components or if you are taking certain medications that interact dangerously with it.

Alcohol should be avoided while taking Trioday 400 Tablet because it can worsen dizziness and increase the risk of liver damage. It is also essential to consult your doctor if you are pregnant, planning to become pregnant, breastfeeding, or are an elderly patient, as dosage adjustments or alternative options may be required.

Uses of Trioday 400 Tablet

Trioday 400 Tablet is prescribed to help manage HIV-1 infection and support immune system function. It may be used for:

  • HIV-1 infection management: Trioday 400 Tablet helps control the Human Immunodeficiency Virus (HIV-1) by reducing the amount of virus in your blood.
  • Immune system support: By lowering the viral load, Trioday 400 Tablet allows your immune system's CD4 cells to recover and help defend your body against other infections.

Key Benefits

Trioday 400 Tablet is a combination antiretroviral medicine used to treat HIV-1 infection. When taken regularly as prescribed, it helps suppress the virus, supports immune function, and reduces the risk of HIV-related complications.

  • Suppresses HIV Replication: Helps reduce the amount of HIV in the body (viral load), allowing the immune system to function more effectively.
  • Supports Immune Health: By controlling HIV infection, it helps preserve and improve immune function, reducing the risk of opportunistic infections and HIV-related illnesses.
  • Provides Complete Combination Therapy: Combines three antiretroviral medicines in a single tablet, providing comprehensive HIV treatment in one regimen.
  • Simplifies Daily Treatment: The once-daily, single-tablet regimen helps reduce pill burden and supports long-term treatment adherence.
  • Reduces the Risk of HIV Transmission: Maintaining an undetectable viral load through consistent treatment greatly reduces the risk of sexually transmitting HIV to others, although it does not eliminate the need for appropriate preventive measures.

Directions for Use

  • Trioday 400 Tablet can be taken on an empty stomach, either 1 hour before or 2 hours after a meal, as prescribed by the doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Swallow Trioday 400 Tablet as a whole with a glass of water.
  • Do not chew, crush, or break it.

How Trioday 400 Tablet Works

Trioday 400 Tablet contains efavirenz, lamivudine, and tenofovir disoproxil, which work together to stop HIV-1 from multiplying. Each component attacks the virus at different points in its life cycle. The first active ingredient, efavirenz, is a non-nucleoside reverse transcriptase inhibitor (NNRTI). It works by directly blocking a specific viral protein called reverse transcriptase, which the virus needs to copy its genetic material. The second and third active ingredients, lamivudine and tenofovir disoproxil, are nucleoside reverse transcriptase inhibitors (NRTIs). They act as faulty building blocks. When the virus tries to build new DNA, it mistakenly uses these ingredients, which abruptly stops the DNA chain from growing and prevents the virus from reproducing. Together, these actions help reduce the amount of HIV-1 in the body and prevent the virus from spreading to new immune cells.
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Alcohol

Caution

Avoid alcohol consumption with Trioday 400 Tablet as it may increase the risk of liver damage.

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Pregnancy

Caution

Trioday 400 Tablet is not recommended for use in pregnant women unless necessary. Let your doctor know if you are pregnant or planning to conceive before taking Trioday 400 Tablet .

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Breast Feeding

Caution

Trioday 400 Tablet is not recommended for use in breastfeeding women since it is excreted into breast milk. Please consult your doctor before taking Trioday 400 Tablet if you are breastfeeding.

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Driving

Caution

Trioday 400 Tablet may cause dizziness and drowsiness in some people. Therefore, avoid driving or operating heavy machinery if you feel dizzy or drowsy after taking Trioday 400 Tablet .

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Liver

Caution

Let your doctor know if you have any history of liver diseases before taking Trioday 400 Tablet . Dose adjustment may be required.

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Kidney

Caution

Let your doctor know if you have any history of kidney diseases before taking Trioday 400 Tablet . Dose adjustment may be required.

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Children

Caution

Trioday 400 Tablet is recommended for children who weigh at least 77 pounds (35 kg) only under the doctor’s supervision.

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Heart

Caution

Please inform your doctor if you have a history of heart disease before taking Trioday 400 Tablet . Your doctor will prescribe it only if the potential benefits outweigh the possible risks.

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Geriatrics

Caution

Trioday 400 Tablet should be used in elderly patients only when prescribed by a doctor. If you have any concerns about using Trioday 400 Tablet for geriatrics, please consult a doctor.

What if I have taken an overdose of Trioday 400 Tablet

If you suspect an overdose or have taken more than the prescribed amount of Trioday 400 Tablet , seek immediate emergency medical attention or contact a poison control centre right away.

Diet & Lifestyle Advise

  • Take the medicine on an empty stomach: Avoid eating high-fat meals right before or after taking Trioday 400 Tablet , as high-fat food can significantly increase the absorption of the medicine, worsening side effects like dizziness and vivid dreams.
  • Support your bone health: Since some ingredients in this medicine can cause bone thinning, make sure your diet includes adequate amounts of calcium and vitamin D, or talk to your doctor about appropriate supplements.
  • Stay hydrated: Drink plenty of fluids throughout the day to support your kidneys, which help filter and clear this medication from your body.
  • Limit alcohol intake: Avoiding alcohol is highly recommended, as both alcohol and the ingredients in Trioday 400 Tablet can stress your liver and increase central nervous system side effects like drowsiness.
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Have a query?

How Soon It Starts Working

The time required for Trioday 400 Tablet to start to work: The time required for Trioday 400 Tablet to show its action is unknown. The time for which the effects of Trioday 400 Tablet last: The duration of action for Trioday 400 Tablet is clinically unknown.

What if you forget to take Trioday 400 Tablet

If you miss a dose of Trioday 400 Tablet , take it as soon as you remember, provided it is not too close to your next scheduled dose. If your next dose is due in a few hours, skip the missed dose and resume your regular schedule. Do not take two doses at the same time to make up for a missed one.

Storage

•Store Trioday 400 Tablet at room temperature, ideally between 20°C and 25°C (68°F to 77°F). •Keep the bottle tightly closed, and keep it out of the reach of children and pets.

Drug Warnings

  • Take at bedtime: Taking Trioday 400 Tablet right before sleep is a highly effective way to sleep through the peak of side effects like dizziness or lightheadedness.
  • Watch for severe skin rashes: Monitor your skin closely during the first few weeks of treatment; if you notice a widespread rash, contact your doctor immediately.
  • Monitor your mental health: Be alert to changes in your mood, sleep patterns, or thoughts. If you experience severe sadness or anxiety, inform your healthcare provider right away.
  • Check your kidney and liver function: Attend all scheduled doctor appointments for routine blood and urine tests to ensure your kidneys and liver remain healthy while taking this medication.
  • Avoid sudden discontinuation: Never stop taking Trioday 400 Tablet without consulting your doctor, as stopping antiretroviral therapy can cause the virus to rapidly multiply and become resistant to future treatments.

verifiedApollotooltip

Trioday 400 Tablet may interact with certain medicines and affect how they work or increase the risk of side effects. Inform your doctor if you are taking any of the following:

  • Other antiviral drugs: Combining Trioday 400 Tablet with other medications containing similar active ingredients can cause severe toxicity.
  • Certain antiseizure medicines: Drugs like carbamazepine or phenytoin can lower the levels of Trioday 400 Tablet in your body, making it less effective.
  • Certain antibiotics and antifungals: Medications like clarithromycin or voriconazole can significantly alter the levels of Trioday 400 Tablet , increasing side effects or reducing efficacy.
  • Herbal supplements: St. John's Wort can drastically decrease the level of Trioday 400 Tablet in your blood, which may lead to treatment failure.

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verifiedApollotooltip

Certain foods and beverages may affect how this medicine works. Keep the following in mind while taking Trioday 400 Tablet :

  • High-fat meals: Consuming high-fat food increases the absorption of the medicine, which can cause severe dizziness, drowsiness, and difficulty concentrating.

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Habit Forming

No

Therapeutic Class

[ANTIRETROVIRAL AGENTS]

FAQs

Trioday 400 Tablet contains Efavirenz, Lamivudine, and Tenofovir disoproxil. It works by interfering with the functioning of nucleotide and nucleoside reverse transcriptase enzymes necessary for the reproduction of the virus. Together, Trioday 400 Tablet helps in treating HIV infection.
Trioday 400 Tablet may cause bone problems, such as osteonecrosis (death of bone tissue due to loss of blood supply to the bone), especially in HIV patients taking combination antiretroviral therapy. If you experience any joint pains, stiffness (especially shoulder, knee or hip) or difficulty in movement, please consult a doctor immediately.
HIV infection may still be transmitted to other persons while using Trioday 400 Tablet . Trioday 400 Tablet reduces the risk of transmission; however, HIV infection is still contagious. Therefore, discuss with a doctor for precautions to avoid transmission of HIV while being treated with Trioday 400 Tablet .
Trioday 400 Tablet does not cure HIV infection. Trioday 400 Tablet reduces the activity of HIV in the body and improves the functioning of the immune system.
Trioday 400 Tablet may cause lactic acidosis (excess of lactic acid in the blood), a rare but severe side effect, especially in women who are very obese and in people with liver diseases. However, if you experience stomach pain, vomiting or nausea while taking Trioday 400 Tablet , please consult a doctor immediately.
It is best to take Trioday 400 Tablet on an empty stomach, preferably at bedtime. Taking it with a meal, especially a high-fat one, can cause your body to absorb too much of the medicine at once, which increases the risk of side effects like dizziness and sleep disturbances. Talk to your doctor or pharmacist if you find it difficult to take it on an empty stomach.
These are common side effects of Trioday 400 Tablet , especially when you first start treatment, and they usually improve within a few weeks. Taking your medicine at bedtime on an empty stomach can help minimise these issues. If these symptoms are severe or do not improve, talk to your doctor.
No, you should never stop taking Trioday 400 Tablet even if your viral load is undetectable and you feel completely healthy. Stopping the medication can cause the virus to multiply quickly, become resistant to the treatment, and damage your immune system. Always talk to your doctor before making any changes.
No, Trioday 400 Tablet does not cure HIV-1, but it is a highly effective treatment that keeps the virus under control and prevents it from multiplying. This helps preserve your immune system so you can live a healthy, long life. Talk to your doctor about long-term management strategies.
It is highly recommended to avoid or strictly limit alcohol while taking Trioday 400 Tablet . Alcohol can worsen central nervous system side effects like dizziness and drowsiness, and it can also increase the strain on your liver. Talk to your doctor about your alcohol consumption.
If you are pregnant, planning to become pregnant, or suspect you might be, you must discuss this with your healthcare provider immediately. Your doctor will weigh the benefits and risks to determine the safest treatment plan for you and your baby. Talk to your doctor for personalised advice.
If you vomit shortly after taking your dose, contact your pharmacist or doctor for guidance. Do not automatically take another dose without professional advice, as it depends on how much time has passed since you took the tablet. Talk to your doctor or pharmacist to be sure.
Yes, some components of Trioday 400 Tablet can affect your kidney function over time. Your doctor will monitor your kidneys through regular blood and urine tests while you are taking this medicine. If you notice changes in your urination patterns or swelling in your feet, talk to your doctor immediately.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Other Info - TRI2011
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