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Triplixam 4mg/1.25mg/5mg Tablet is used to treat hypertension (high blood pressure). It works by relaxing and widening the blood vessels, thereby improving blood flow and making it easier for the heart to pump blood through them. It also increases the amount of urine produced by the kidneys. Thereby, this medicine helps lower blood pressure, thus, reducing the chances of heart problems such as heart attack and stroke.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

AMLODIPINE-5MG+INDAPAMINE-1.25MG+PERINDOPRIL ERBUMINE-4MG

Manufacturer/Marketer :

Serdia Pharmaceuticals India Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Triplixam 4mg/1.25mg/5mg Tablet

Triplixam 4mg/1.25mg/5mg Tablet is a combination prescription tablet used to treat high blood pressure (hypertension). It brings together three active medicines to help relax your blood vessels and improve your body's fluid balance. By keeping your blood pressure under control, Triplixam 4mg/1.25mg/5mg Tablet reduces your risk of serious heart problems, strokes, and kidney disease.

For the best results, you should take Triplixam 4mg/1.25mg/5mg Tablet consistently at the same time every day, usually in the morning before breakfast. It is designed for daily, long-term use even if you feel completely healthy, as high blood pressure often has no symptoms. Incorporating a low-sodium diet, regular moderate exercise, and stress management can significantly support Triplixam 4mg/1.25mg/5mg Tablet 's effectiveness.

While taking Triplixam 4mg/1.25mg/5mg Tablet , some people may experience mild side effects such as a dry cough, ankle swelling, or mild dizziness when standing up. These symptoms are often temporary, but you should speak with your doctor or pharmacist if they persist. Seek immediate medical care if you develop signs of an allergic reaction, such as swelling of your face, lips, or throat, or if you feel severe dizziness.

Tell your doctor about your complete medical history before starting Triplixam 4mg/1.25mg/5mg Tablet , especially if you have kidney problems, liver damage, diabetes, or a history of swelling in your face or throat. Do not take this if you are pregnant or planning to become pregnant, as it can cause serious harm to an unborn baby.

This medication can interact with other drugs, such as potassium supplements, water pills, pain relievers like ibuprofen, or lithium, which may change how your medicine works or increase side effects. Limit your alcohol intake while taking Triplixam 4mg/1.25mg/5mg Tablet , as alcohol can cause your blood pressure to drop too low, making you feel dizzy or faint. Breastfeeding individuals and elderly patients should consult their healthcare provider to ensure this treatment is safe for their specific needs.

Uses of Triplixam 4mg/1.25mg/5mg Tablet

Triplixam 4mg/1.25mg/5mg Tablet is used in the treatment of Hypertension (high blood pressure). The detailed uses of Triplixam 4mg/1.25mg/5mg Tablet are as follows:

  • High blood pressure (hypertension): Triplixam 4mg/1.25mg/5mg Tablet helps lower blood pressure to a normal range by relaxing blood vessels and reducing extra fluid in the body, which helps prevent future strokes, heart attacks, and kidney failure.

Key Benefits

Triplixam 4mg/1.25mg/5mg Tablet help control high blood pressure and support long-term cardiovascular health by combining three blood pressure medicines. Consistent blood pressure control helps protect vital organs and reduces the risk of serious complications.

Benefits may include:

  • Helps lower and maintain healthy blood pressure levels.
  • Reduces the risk of heart attack, stroke, and other cardiovascular complications.
  • Supports healthy heart, brain, and kidney function by protecting them from long-term high blood pressure.
  • Provides consistent blood pressure control throughout the day.
  • Simplifies treatment by combining three medicines into a single daily tablet, helping improve treatment adherence.
  • Promotes long-term cardiovascular health and overall well-being.
Side effects of Triplixam 4mg/1.25mg/5mg Tablet
Here are the seven steps to manage medication-triggered Dyspnea (Difficulty Breathing or Shortness of Breath):
  • Tell your doctor immediately if you experience shortness of breath after taking medication.
  • Your doctor may adjust the medication regimen or dosage or give alternative medical procedures to minimize the symptoms of shortness of breath.
  • Monitor your oxygen levels and breathing rate regularly to track changes and potential side effects.
  • For controlling stress and anxiety, try relaxation techniques like deep breathing exercises, meditation, or yoga.
  • Make lifestyle changes, such as quitting smoking, exercising regularly, and maintaining a healthy weight.
  • Seek emergency medical attention if you experience severe shortness of breath, chest pain, or difficulty speaking.
  • Follow up regularly with your doctor to monitor progress, adjust treatment plans, and address any concerns or questions.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Avoid triggers like alcohol, caffeine, and energy drinks.
  • Try relaxation techniques such as yoga, meditation, or deep breathing.
  • Exercise regularly as it helps maintain heart health.
  • Follow a nutritious and balanced diet.
Managing Medication-Triggered Flushing (Reddening of the skin): A Step-by-Step Guide:
  • Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication or providing guidance on managing your erythema symptoms.
  • Your doctor may recommend or prescribe certain medications to help alleviate symptoms.
  • Apply cool compresses or calamine lotion to the affected skin area to reduce redness and itching.
  • Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin hydrated.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • If you suspect the medication may be affecting your vision, consult your doctor or an eye specialist.
  • Get your vision checked before and during treatment to monitor for any problems.
  • You may need to adjust or stop your medication to manage side effects.
  • Vision loss due to high pressure inside the eye (intraocular pressure) can be treated with medication or laser therapy.
  • Cataract-related vision loss may require surgery.
  • Eating a diet rich in fruits and vegetables, including carrots and dark leafy greens such as kale, spinach, and collard greens, can provide essential nutrients to help keep your eyes healthy.

Directions for Use

  • Triplixam 4mg/1.25mg/5mg Tablet can taken with or without food, but it is often recommended to take it before a meal for optimal effectiveness.
  • It is usually taken once daily, preferably in the morning, or as prescribed by your doctor.
  • Swallow Triplixam 4mg/1.25mg/5mg Tablet as a whole with a glass of water.
  • Do not break, chew, or crush it.

How Triplixam 4mg/1.25mg/5mg Tablet Works

Triplixam 4mg/1.25mg/5mg Tablet contains Indapamide, Amlodipine, and Perindopril Erbumine. Indapamide: It helps the body remove excess salt and water through urine. This reduces the amount of fluid in the blood vessels, helping to lower blood pressure and improve circulation. Amlodipine: It helps relax and widen the blood vessels, allowing blood to flow more easily. This helps lower blood pressure and reduces the workload on the heart. Perindopril Erbumine: It helps keep blood vessels relaxed and open, improving blood flow throughout the body. This helps lower blood pressure, reduces the strain on the heart, and supports long-term heart and blood vessel health.
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Alcohol

Unsafe

Avoid consuming alcohol as it might cause increased dizziness.

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Pregnancy

Consult your doctor

Triplixam 4mg/1.25mg/5mg Tablet is not recommended during early pregnancy and should not be taken when more than 3 months pregnant as it may cause serious harm to the baby. Please consult your doctor if you are pregnant, think you are pregnant or planning for pregnancy.

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Breast Feeding

Unsafe

Triplixam 4mg/1.25mg/5mg Tablet is not recommended for breastfeeding mothers. Talk to your doctor if you have any concerns.

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Driving

Unsafe

Triplixam 4mg/1.25mg/5mg Tablet may cause dizziness, do not drive or operate heavy machinery if you feel dizzy.

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Liver

Caution

Dose adjustment may be needed. Please consult your doctor if you have liver problems or any concerns regarding this. Avoid taking Triplixam 4mg/1.25mg/5mg Tablet if you have severe liver disease or hepatic encephalopathy.

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Kidney

Caution

Dose adjustment may be needed. Avoid taking Triplixam 4mg/1.25mg/5mg Tablet if you have severe kidney problems. Please consult your doctor if you have kidney problems or any concerns regarding this.

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Children

Unsafe

Triplixam 4mg/1.25mg/5mg Tablet is not recommended for children as safety and effectiveness have not been established.

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Heart

Caution

Triplixam 4mg/1.25mg/5mg Tablet should be used with caution in patients with heart problems. Inform your doctor about any heart-related conditions before taking Triplixam 4mg/1.25mg/5mg Tablet .

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Geriatrics

Caution

Triplixam 4mg/1.25mg/5mg Tablet should be given with caution in elderly patients due to an increased risk of side effects. Dose adjustment may be required based on their health condition.

What if I have taken an overdose of Triplixam 4mg/1.25mg/5mg Tablet

If you take too much of Triplixam 4mg/1.25mg/5mg Tablet , you may experience severe dizziness, fainting, or a rapid heartbeat due to a sudden drop in blood pressure. Seek emergency medical attention immediately.

Diet & Lifestyle Advise

  • Reduce your salt intake: Cut back on dietary sodium by avoiding processed foods and using herbs or spices for flavor instead of table salt. Less salt helps the water pill component work more effectively.
  • Monitor your potassium intake: Since Triplixam 4mg/1.25mg/5mg Tablet can affect potassium levels in your blood, talk to your doctor before using potassium-containing salt substitutes or taking potassium supplements.
  • Stay active: Aim for at least 30 minutes of moderate exercise, such as brisk walking, most days of the week to naturally help lower your blood pressure.
  • Avoid grapefruit juice: Grapefruit and grapefruit juice can increase the level of amlodipine in your body, which may cause your blood pressure to drop too low or increase side effects.
  • Limit alcohol consumption: Restricting alcohol helps prevent severe blood pressure drops and reduces the risk of dizziness or fainting.
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How Soon It Starts Working

  • The time required for Triplixam 4mg/1.25mg/5mg Tablet to start to work: Triplixam 4mg/1.25mg/5mg Tablet shows its action within 1 to 2 hours of administration.
  • The time for which the effects of Triplixam 4mg/1.25mg/5mg Tablet last: Triplixam 4mg/1.25mg/5mg Tablet effect lasts for 12 to 24 hours.

What if you forget to take Triplixam 4mg/1.25mg/5mg Tablet

If you miss a dose of Triplixam 4mg/1.25mg/5mg Tablet , take it as soon as you remember on the same day. If it is almost time for your next scheduled dose, skip the missed dose and return to your regular schedule. Do not take a double dose to make up for a missed one.

Storage

• Store Triplixam 4mg/1.25mg/5mg Tablet at room temperature, ideally between 20°C and 25°C (68°F to 77°F).

Drug Warnings

  • Check your blood pressure regularly: Keep a written log of your blood pressure readings at home to share with your doctor during checkups.
  • Rise slowly from sitting or lying down: Triplixam 4mg/1.25mg/5mg Tablet can cause dizziness when you stand up quickly. Give your body a moment to adjust to reduce the risk of falling.
  • Watch for signs of dehydration: If you experience severe vomiting, diarrhea, or heavy sweating, contact your doctor, as excessive fluid loss can cause your blood pressure to drop dangerously low.
  • Avoid driving if you feel dizzy: Do not drive or operate machinery until you know how Triplixam 4mg/1.25mg/5mg Tablet affects you, especially during the first few days of starting the treatment.
  • Rise slowly to prevent dizziness: You may feel more dizzy when you first start Triplixam 4mg/1.25mg/5mg Tablet or after your dose is increased. Stand up gradually from a sitting or lying position, and contact your doctor if the dizziness is severe, persistent, or leads to fainting.
  • Inform your dentist and surgeons: If you need surgery or a dental procedure, let your provider know you are taking this medication, as it can interact with anesthetics.

Drug-Drug Interactions

verifiedApollotooltip
  • Potassium supplements or potassium-sparing diuretics (water pills): Taking these medicines alongside Triplixam 4mg/1.25mg/5mg Tablet may increase potassium levels in the blood, raising the risk of serious heart rhythm problems.
  • Nonsteroidal anti-inflammatory drugs (NSAIDs) (e.g., ibuprofen, naproxen): These medicines may reduce the blood pressure-lowering effect of Triplixam 4mg/1.25mg/5mg Tablet and increase the risk of kidney damage.
  • Medicine for bipolar disorder (e.g., Lithium): Taking lithium alongside Triplixam 4mg/1.25mg/5mg Tablet may increase lithium levels in the body, raising the risk of lithium toxicity.
  • Other blood pressure medicines: Combining these with Triplixam 4mg/1.25mg/5mg Tablet may cause your blood pressure to drop too low, leading to dizziness or fainting.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

verifiedApollotooltip
  • Grapefruit and grapefruit juice: Avoid consuming grapefruit products while taking Triplixam 4mg/1.25mg/5mg Tablet , as they may increase the amount of the amlodipine component in your bloodstream and raise the risk of dizziness, low blood pressure, or ankle swelling.
  • Alcohol: Avoid or limit alcohol while taking Triplixam 4mg/1.25mg/5mg Tablet , as it may further lower your blood pressure and increase dizziness, lightheadedness, or fainting.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTI- HYPERTENSIVES]

FAQs

Triplixam 4mg/1.25mg/5mg Tablet belongs to the group of anti-hypertensive medicines used to treat high blood pressure (hypertension).
Triplixam 4mg/1.25mg/5mg Tablet contains Indapamide, Amlodipine, and Perindopril erbumine. Indapamide lowers blood pressure by increasing the amount of urine produced by the kidneys. Amlodipine relaxes the blood vessels, thereby improving blood flow. Perindopril erbumine widens the blood vessels; this makes it easier for the heart to pump blood through them. Together, Triplixam 4mg/1.25mg/5mg Tablet helps treat high blood pressure.
Triplixam 4mg/1.25mg/5mg Tablet may cause palpitations, a sensation that the heart is racing, pounding, or fluttering. A minor fluctuation should not be a worry; however, if palpitations continue or you begin to feel unwell, speak with your doctor.
High blood pressure increases the workload on the arteries and heart. If untreated, it could damage the blood vessels of the heart, brain, kidney and might result in stroke, heart failure or kidney failure. Hypertension increases the risk of heart attacks. Therefore, anti-hypertensives such as Triplixam 4mg/1.25mg/5mg Tablet are used to lower the blood pressure to normal; this reduces the risk of developing these disorders.
Avoid consuming grapefruit and grapefruit juice whilst taking Triplixam 4mg/1.25mg/5mg Tablet as it might increase the blood levels of amlodipine; this can lead to an unpredictable increase in the blood pressure-lowering effect of Triplixam 4mg/1.25mg/5mg Tablet . Inform your doctor if you are on a salt-restricted diet, use salt substitutes or if you are taking potassium supplements.
Triplixam 4mg/1.25mg/5mg Tablet may cause diarrhoea as a common side effect in some individuals. If you experience this symptom, drink plenty of water to stay hydrated, eat the BRAT diet, which includes bananas, rice, applesauce, and toast, and limit your intake of high-fibre foods, fatty foods and spicy foods.
Triplixam 4mg/1.25mg/5mg Tablet is usually taken with or without food. However, it is often recommended to take it before a meal for optimal effectiveness. It's important to follow the instructions provided by the doctor for the best results.
Triplixam 4mg/1.25mg/5mg Tablet is not known to cause weight gain. However, if you experience any weight changes, manage it with lifestyle changes like exercising regularly, eating nutritious-rich food, staying hydrated, limiting your intake of sugary foods and cutting down on carbs.
The side effects of Triplixam 4mg/1.25mg/5mg Tablet include headache, oedema, dizziness, flushing, and abdominal pain. Consult the doctor if any of these symptoms persist or worsen.
If you become pregnant while taking Triplixam 4mg/1.25mg/5mg Tablet , contact your doctor immediately. Because Triplixam 4mg/1.25mg/5mg Tablet can seriously harm an unborn baby, your doctor will advise you on stopping it safely and changing to a more suitable treatment as soon as possible.
You may notice a decrease in your blood pressure within a few days of starting Triplixam 4mg/1.25mg/5mg Tablet , but it can take several weeks to reach its full therapeutic effect. Continue taking Triplixam 4mg/1.25mg/5mg Tablet daily even if you do not feel any immediate changes, and talk to your doctor.
One of the active ingredients in Triplixam 4mg/1.25mg/5mg Tablet is known to cause a dry, tickly, and persistent cough in some patients. This cough is harmless but can be annoying and cannot be treated with standard cough medicines. If the cough becomes troublesome, talk to your doctor.
No. Do not stop taking Triplixam 4mg/1.25mg/5mg Tablet without consulting your doctor, even if your blood pressure is normal. High blood pressure is usually a long-term condition that is controlled, not cured, by medication. Stopping treatment may cause your blood pressure to rise again and increase your risk of serious complications such as heart attack or stroke. Continue taking Triplixam 4mg/1.25mg/5mg Tablet exactly as prescribed and speak with your doctor before making any changes.
Yes, ankle swelling (edema) is a known side effect of one of the ingredients in Triplixam 4mg/1.25mg/5mg Tablet . It happens because the blood vessels relax and fluid can accumulate in your lower extremities. If the swelling is uncomfortable or gets worse, talk to your doctor.
You should avoid taking pain relievers like ibuprofen or naproxen regularly while on Triplixam 4mg/1.25mg/5mg Tablet . These drugs can prevent your blood pressure medicine from working effectively and may increase the strain on your kidneys. Talk to your doctor or pharmacist about safer pain relief alternatives.
Yes. Triplixam 4mg/1.25mg/5mg Tablet may cause dizziness or light-headedness, especially when you first start treatment, after a dose increase, or when standing up quickly due to a drop in blood pressure. If this happens, sit or lie down until you feel better and rise slowly from a sitting or lying position. Monitor your blood pressure as advised by your doctor. If the dizziness is severe, persistent, or causes you to faint, seek medical advice promptly.
Yes, your doctor will likely order regular blood tests to check your kidney function and monitor the levels of minerals in your blood, such as potassium and sodium, such as potassium and sodium, in your blood. These routine checks help ensure that Triplixam 4mg/1.25mg/5mg Tablet is working safely for you. Talk to your doctor to set up your monitoring schedule.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Serdia House, Off Dr. S S Rao Road, Behind M G Hospital Parel, Mumbai 400012
Other Info - TRI1450
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