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compositionComposition:PIRIBEDIL-50MG
prescription
Prescription Medicine
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Trivastal LA Tablet is used in the treatment of Parkinson's disease. It contains Piribedil, which increases dopamine (chemical messenger important for movement control) levels in the brain. It can effectively treat symptoms of Parkinson's disease and improve the quality of life. It may cause common side effects such as nausea, vomiting, flatulence (gas), confusion, hallucinations, dizziness, and drowsiness.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Composition :

PIRIBEDIL-50MG

Manufacturer/Marketer :

Serdia Pharmaceuticals India Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Trivastal LA Tablet

Trivastal LA Tablet is an oral prescription medication primarily used to manage symptoms of Parkinson’s disease and age-related mental decline. Its main medical purpose is to restore chemical balance in the brain, which helps control physical movements and support cognitive functions like memory and attention. It is commonly prescribed to help patients maintain their physical independence and mental clarity.

To get the best results, you must take Trivastal LA Tablet regularly and exactly as prescribed by your doctor, usually at the same times each day. You should take this tablet with a glass of water at the end of a main meal to help prevent stomach discomfort. Incorporating mild physical exercises, like walking, and eating a high-fibre diet can significantly improve your overall outcomes while taking this medication.

While taking Trivastal LA Tablet , you may experience common side effects like mild nausea, stomach gas, or feeling unusually sleepy during the day. However, if you experience serious issues such as sudden, uncontrollable sleep attacks, confusion, or seeing things that are not there, you must contact your doctor right away.

Before starting this medication, tell your doctor if you have a history of heart disease, blood pressure problems, or kidney issues. Do not take this if you are allergic to any of its ingredients, have recently had a heart attack, or are experiencing severe cardiovascular shock.

This medicine can interact with alcohol, smoking, and certain medications like antipsychotics, which can either worsen drowsiness or stop the treatment from working effectively. If you are pregnant, planning to become pregnant, breastfeeding, or are an elderly individual, you should talk to your doctor to ensure this treatment is safe for you.

Uses of Trivastal LA Tablet

Trivastal LA Tablet is used to manage symptoms of Parkinson’s disease and age-related mental decline. The detailed uses of Trivastal LA Tablet are as follows:

  • Parkinson's disease: Helps reduce tremors, muscle stiffness, and slow body movements by acting directly on brain receptors.
  • Age-related mental decline: Helps improve attention, memory, and concentration in elderly individuals facing mild cognitive difficulties.
  • Circulatory issues: Aids in relieving leg pain and cramping while walking caused by poor blood circulation in the lower limbs.

Key Benefits

Trivastal LA Tablet offers meaningful support to help you manage your daily life with greater comfort and independence. By targeting specific pathways in the brain, it provides steady relief from physical and cognitive challenges.

  • Smoother physical movement: By easing muscle stiffness and tremors, this medicine helps you perform daily tasks like writing, buttoning clothes, or walking with much greater ease.
  • Sharper mental focus: It helps clear mental fog, allowing elderly individuals to maintain better attention, memory, and daily cognitive function.
  • Better walking tolerance: For those suffering from poor leg circulation, it helps reduce pain during physical activity, helping you walk longer distances comfortably.
Side effects of Trivastal LA Tablet
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the steps to manage Gastrointestinal Air and Swelling (GAS) caused by medication:
  • Tell your doctor about your GAS symptoms. They may change your medication regimen or prescribe additional drugs to help you manage them.
  • To manage GAS symptoms, eat a balanced diet of fibre, vegetables, and fruits.
  • Drink enough water throughout the day to avoid constipation and treat GAS symptoms.
  • Regular exercise like yoga and walking may help stimulate digestion and alleviate GAS symptoms.
  • Take probiotics only if your doctor advises, as they may help alleviate GAS symptoms by promoting gut health.
  • Take medication for GAS symptoms only if your doctor advises, as certain medications can interact with your existing prescriptions or worsen symptoms.
  • If symptoms persist, worsen, or are accompanied by severe abdominal pain, vomiting, or bleeding, seek immediate medical attention.
  • Confusion is a major psychotic disorder that needs immediate medical attention.
  • Acknowledge your experience and put effort to control confusion.
  • Avoid smoking and alcohol intake as it can worsen the condition and increase your confusion.
  • Practice meditation and yoga to avoid anxiety, which can be one of the leading causes.
  • Talk to your dietician and consume food that can improve your mental health.
  • Hallucination is a major psychotic disorder that needs immediate medical attention.
  • Acknowledge your experience and put effort to control hallucinations. You can share what is being seen with a therapist to know whether they are real or imaginary.
  • Avoid smoking and alcohol intake as it can worsen the condition and increase your imagination.
  • Practice meditation and yoga to avoid anxiety, which can be one of the leading causes of hallucinations.
  • Talk to your dietician and consume food that can improve your mental health.
  • Manage stress by practising deep breathing, yoga or meditation.
  • Participating in activities you enjoy, or exercising may also help manage agitation.
  • Get enough sleep. Maintain a regular sleep cycle.
  • Exercise regularly. Try physical activities like walking, running, or dancing.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

Directions for Use

  • Trivastal LA Tablet is preferably taken after food to avoid stomach and intestinal side effects.
  • Follow your doctor’s recommendations on the dosage and timing of this medication to achieve optimal results.
  • Swallow it as a whole with a glass of water.
  • Do not crush, chew, or break it.

How Trivastal LA Tablet Works

To understand how Trivastal LA Tablet works, it helps to look at how the brain controls movement and memory. The brain relies on a natural chemical messenger called dopamine to coordinate smooth muscle actions and maintain sharp cognitive focus. In conditions like Parkinson's disease or age-related mental decline, the brain's dopamine levels drop significantly. Trivastal LA Tablet contains piribedil, which acts directly as a dopamine agonist. This means it mimics the role of dopamine by binding to and stimulating dopamine receptors in the brain. By tricking the brain into acting as though dopamine is fully present, the medicine helps restore balance, leading to smoother physical movements and better mental clarity. Additionally, it helps dilate blood vessels, which supports healthy blood flow to vital tissues.
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Alcohol

Caution

Trivastal LA Tablet may interact with alcohol as it causes excessive drowsiness.

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Pregnancy

Unsafe

There is no relevant data to establish the safe use of Trivastal LA Tablet in pregnant women as Trivastal LA Tablet is restricted for use in elderly patients.

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Breast Feeding

Unsafe

There is no relevant data to establish the safe use of Trivastal LA Tablet in breastfeeding mothers as Trivastal LA Tablet is restricted for use in elderly patients.

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Driving

Unsafe

Do not drive or operate heavy machinery as Trivastal LA Tablet may cause sudden onset of drowsiness.

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Liver

Caution

Trivastal LA Tablet may affect liver function when given in high doses. So, the dose may have to be adjusted by your doctor in patients with liver diseases.

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Kidney

Caution

There is no relevant data to establish the safe use of Trivastal LA Tablet in patients with kidney disease. So, it should be used with caution.

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Children

Unsafe

There is no relevant data to establish the safe use of Trivastal LA Tablet in children as Trivastal LA Tablet is restricted for elderly patients.

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Heart

Consult your doctor

Limited information is available; please consult your doctor.

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Geriatrics

Consult your doctor

Limited information available for use of Trivastal LA Tablet in elderly patients. Please consult your doctor.

What if I have taken an overdose of Trivastal LA Tablet

In case of an accidental overdose, seek immediate emergency medical attention. Symptoms of an overdose may include severe nausea, vomiting, unstable blood pressure, or extreme confusion.

Diet & Lifestyle Advise

  • Increase dietary fibre: To counter constipation, which is common in Parkinson's disease, consume fibre-rich foods like fruits, vegetables, and whole grains.
  • Stay hydrated: Drink plenty of water throughout the day to support healthy digestion and help manage blood pressure.
  • Change positions slowly: To avoid sudden dizziness, sit on the edge of your bed or chair for a few seconds before standing up.
  • Keep physically active: Engage in regular, low-impact exercises such as stretching, walking, or physical therapy to maintain muscle strength and flexibility.

 

health query

Have a query?

How Soon It Starts Working

The time required for Trivastal LA Tablet to start to work: Trivastal LA Tablet ideally shows its action within 1 to 2 hours after administration. The time for which the effects of Trivastal LA Tablet last: The effect of Trivastal LA Tablet lasts for 12 to 24 hours.

What if you forget to take Trivastal LA Tablet

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Storage

Store Trivastal LA Tablet at room temperature, ideally between 15°C and 30°C (59°F to 86°F), •Keep the tablets in their original packaging to protect them from environmental elements, and never store them in damp places like bathrooms.

Drug Warnings

  • Do not drive, use tools, or operate heavy machinery if you feel dizzy or experience sudden sleepiness.
  • Always inspect the blister pack before taking your tablet; do not use the medicine if the packaging is torn or damaged.
  • Do not stop taking Trivastal LA Tablet abruptly, as a sudden halt can trigger a dangerous reaction with high fever and muscle stiffness; your doctor will guide you on gradually reducing dose.
  • Ask a family member or caregiver to help monitor your behaviour for any signs of unusual impulsiveness, such as gambling or shopping binges.
  • Avoid drinking alcohol while on this medication, as it can dangerously increase drowsiness and make you feel highly disoriented.

Drug-Drug Interactions

verifiedApollotooltip
  • Antipsychotic medications (neuroleptics): These drugs can block the action of Trivastal LA Tablet , making your treatment less effective.
  • Blood pressure medications: Combining these with Trivastal LA Tablet may cause an excessive drop in blood pressure, leading to severe dizziness.
  • Sedatives and sleeping pills: Taking these together can severely increase drowsiness and the risk of sudden sleep attacks.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

verifiedApollotooltip
  • Alcohol: Drinking alcohol while taking this medicine can cause extreme drowsiness, coordination issues, and unpredictable blood pressure changes.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTIPARKINSON AGENTS]

FAQs

Trivastal LA Tablet is used in the treatment of Parkinson's disease.
Trivastal LA Tablet contains 'Piribedil', which is used to treat Parkinson's disease. It increases dopamine levels, a chemical messenger in the brain that causes symptoms of Parkinson's disease.
Yes. Trivastal LA Tablet may cause drowsiness, dizziness, or sudden episodes of falling asleep without warning. Do not drive, operate machinery, or perform hazardous activities if you experience these symptoms. If you develop sudden sleep attacks or excessive daytime sleepiness, contact your doctor promptly, as your treatment may need to be adjusted.
Before taking Trivastal LA Tablet , you should inform your doctor if you have hypertension or other heart diseases. However, Trivastal LA Tablet should not be used in patients with heart failure, or serious heart diseases.
No. Trivastal LA Tablet is not indicated for the treatment of depression. It is used to treat Parkinson's disease. If you have symptoms of depression, speak with your doctor, who can recommend appropriate treatment.
While taking Trivastal LA Tablet , take it after a meal with a full glass of water to help reduce stomach upset. Rise slowly from sitting or lying positions because the medicine may cause a sudden drop in blood pressure and dizziness. It may also cause drowsiness or sudden sleep attacks, so avoid driving or operating machinery if affected. Inform your doctor immediately if you or your family notice unusual behaviours such as compulsive gambling, excessive spending, overeating, or increased sexual urges.
Inform the doctor about your health condition and medications you are taking. Let the doctor know if you are pregnant or breastfeeding.
Trivastal LA Tablet may not be recommended for people with cardiovascular shock (a serious condition in which the heart suddenly stops pumping blood) and acute myocardial infarction (heart attack). Consult the doctor if you have heart or blood pressure problems before starting Trivastal LA Tablet .
Do not take more than the prescribed dose of Trivastal LA Tablet as it may cause an overdose. Overdosage symptoms of Trivastal LA Tablet are low/high blood pressure, nausea, and vomiting. If you suspect you have taken an overdose, please consult a doctor immediately.
The common side effects of Trivastal LA Tablet are nausea, vomiting, flatulence, agitation, dizziness, and drowsiness. These side effects usually improve after discontinuation of therapy. However, if any of these side effects persist or worsen during or after the treatment, inform your doctor immediately.
No, you must never stop taking this medicine suddenly, even if you feel completely fine. Stopping abruptly can cause severe withdrawal symptoms. Your doctor will help you by gradually reducing the dose when necessary. Talk to your doctor before making any changes.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. CDSCO. [Accessed on 02 Jun. 2026]Check here
  2. Spc Trivastal. [Accessed on 02 Jun. 2026]Check here
  3. Piribedil Piribedil. 2020. [Accessed on 10 Feb. 2026]Check here
  4. Ministry of Health and Family Welfare. National Formulary of India (NFI) 2021. 6th ed. New Delhi, India: IPC; 2021. Clinical Drug Monographs: Trivastal La Tablet Sr

Country of origin

India

Manufacturer/Marketer address

Serdia House, Off Dr. S S Rao Road, Behind M G Hospital Parel, Mumbai 400012
Other Info - TRI0036

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