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Trpe Plus Tablet 10's is used to treat schizophrenia. It contains Trifluoperazine and Trihexyphenidyl which work by inhibiting a chemical messenger (dopamine) in the brain that regulates mood. In some cases, this medicine may cause side effects such as nausea, constipation, dryness in the mouth, sedation, weight gain, and dizziness. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Manufacturer/Marketer :

Cerin Pharma

Consume Type :

Oral

Return Policy :

Not Returnable

About Trpe Plus Tablet 10's

Trpe Plus Tablet 10's is a combination prescription medication used primarily to treat schizophrenia and other psychotic disorders. It is also highly effective in managing abnormal, involuntary muscle movements that can occur as side effects of other psychiatric medications. By targeting chemical imbalances in the brain, this medicine helps restore calmer, more organised thinking.

For the best results, you must take Trpe Plus Tablet 10's regularly and consistently at the same times each day. You can take this medication with or without food, though taking it with a meal may help prevent mild stomach upset. Making simple daily adjustments, such as drinking plenty of fluids and avoiding extreme heat, can help your body adapt more easily to the treatment.

While taking Trpe Plus Tablet 10's, you may experience some common side effects, such as dry mouth, blurred vision, or mild drowsiness. These are usually manageable, but you must contact your doctor immediately if you notice more serious signs, such as extreme muscle stiffness, a sudden high fever, or an irregular heart rate.

Before starting this medication, tell your doctor if you have a history of glaucoma, prostate enlargement, heart conditions, or kidney issues. Do not take this if you have severe liver damage, narrow-angle glaucoma, or a history of bone marrow depression. Your doctor will help evaluate if this medication is safe for your specific health history.

Some substances can interact with Trpe Plus Tablet 10's, so you should avoid drinking alcohol or taking over-the-counter sleeping aids while using this medication, as they can cause extreme drowsiness. If you smoke, let your doctor know, as smoking can change how your body processes this medicine.

Consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Speak openly with your doctor, as this medicine may carry risks of extrapyramidal symptoms in newborns or neonatal withdrawal, which is highest in the third trimester. Consult your doctor if managing care for an elderly individual to discuss specific safety precautions.

Uses of Trpe Plus Tablet 10's

Trpe Plus Tablet 10's is used to treat schizophrenia and other psychotic disorders on a long-term basis. The detailed uses of Trpe Plus Tablet 10's are as follows:

  • Schizophrenia and psychotic disorders: Trpe Plus Tablet 10's helps relieve symptoms such as hearing voices, seeing things that are not there, and experiencing deep suspicion or disorganised thinking.
  • Drug-induced movement disorders (extrapyramidal symptoms): Trpe Plus Tablet 10's helps treat and prevent physical side effects like tremors, muscle spasms, and severe muscle stiffness caused by other psychiatric medications.

Key Benefits

Managing schizophrenia can be emotionally challenging, and this medicine is here to help make that journey easier. Trpe Plus Tablet 10's offers comprehensive relief by addressing both mental and physical symptoms simultaneously. By restoring chemical balance in the brain, this medicine brings several key health benefits:

  • Reduce distracting thoughts: It helps reduce distressing thoughts and hallucinations, allowing you to think more clearly and engage more comfortably in daily social and professional activities.
  • Relaxes muscles: This medication helps relax stiff, tense muscles and reduces involuntary shaking or restlessness.
  • Improves movement: This physical relief makes daily movements smoother and pain-free, helping you maintain your independence and overall physical comfort.

Directions for Use

  • Take Trpe Plus Tablet 10's, preferably with food to avoid stomach upset or as advised by the doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow it as a whole with a glass of water.
  • Do not crush, chew or break it.

How Trpe Plus Tablet 10's Works

Trpe Plus Tablet 10's combines two active ingredients that work together to balance brain chemistry and muscle control: Trifluoperazine belongs to a class of medicines called typical antipsychotics. It works by blocking dopamine receptors in the brain, which helps control overactive nerve pathways that lead to hallucinations, delusions, and severe anxiety. Trihexyphenidyl is an anticholinergic medicine. It balances another chemical messenger called acetylcholine, which often becomes overactive when dopamine is blocked. This action helps relieve the muscle stiffness, shaking, and spasms that can occur during antipsychotic treatment.
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Alcohol

Unsafe

Avoid consumption of alcohol with Trpe Plus Tablet 10's as it may increase the risk of drowsiness and other adverse effects.

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Pregnancy

Unsafe

Trpe Plus Tablet 10's is not recommended for use during pregnancy, especially in the third trimesters as it may cause adverse effects in the baby. Please consult a doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Caution

Trpe Plus Tablet 10's may be unsafe to use during breastfeeding. Please consult a doctor if you are breastfeeding.

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Driving

Unsafe

Trpe Plus Tablet 10's may cause dizziness, double vision or drowsiness in some people. Therefore, avoid driving if you feel drowsy, dizzy or experience any vision problems after taking Trpe Plus Tablet 10's.

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Liver

Unsafe

Trpe Plus Tablet 10's is not recommended for patients suffering from Liver diseases/conditions. Please consult a doctor if you have any concerns regarding this.

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Kidney

Caution

Take Trpe Plus Tablet 10's with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Unsafe

Please consult your paediatrician. Your child's doctor may weigh the benefits and risks before prescribing this medicine to your child.

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Heart

Caution

Trpe Plus Tablet 10's should be used with caution in patients with heart problems. Inform your doctor about any heart-related conditions before taking Trpe Plus Tablet 10's.

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Geriatrics

Caution

Trpe Plus Tablet 10's should be given with caution in elderly patients due to an increased risk of side effects. It is important to inform your doctor before using it.

What if I have taken an overdose of Trpe Plus Tablet 10's

In case of an accidental overdose, seek emergency medical attention immediately. Symptoms of an overdose can include severe dry mouth, extreme sleepiness, a rapid heart rate, confusion, or difficulty breathing.

Diet & Lifestyle Advise

  • Stay hydrated: Drink regular sips of water, chew sugar-free gum, or suck on ice chips to help relieve dry mouth.
  • Eat more fibre: Eat a fibre-rich diet with plenty of whole grains, fruits, and vegetables to help prevent constipation.
  • Stand up slowly: Rise from sitting or lying down to prevent dizziness or lightheadedness caused by sudden changes in blood pressure.
  • Avoid overheating: Avoid prolonged exposure to hot weather and stay well hydrated, as this medicine can reduce your body's ability to sweat, increasing your risk of heatstroke.
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How Soon It Starts Working

The time required for Trpe Plus Tablet 10's to start to work: Trpe Plus Tablet 10's ideally shows its action within 1 hour after administration. The time for which the effects of Trpe Plus Tablet 10's last: The effect of Trpe Plus Tablet 10's lasts for 6 to 12 hours.

What if you forget to take Trpe Plus Tablet 10's

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular schedule. Do not take a double dose to make up for a missed one.

Storage

• Store Trpe Plus Tablet 10's at room temperature, ideally between 20°C and 25°C (68°F to 77°F).• Keep the tablets in their original packaging to protect them from direct light and moisture, and avoid storing them in damp areas, such as bathroom cabinets.

Drug Warnings

  • Do not stop suddenly: Do not stop taking medicine suddenly, as doing so can cause your symptoms to return or lead to uncomfortable withdrawal effects.
  • Dose reduction: To avoid withdrawal effects, dose reduction over weeks is preferred under supervision.
  • Take care while driving: Avoid driving, riding a bicycle, or operating heavy machinery until you are certain how this medication affects your vision and alertness.
  • Protect your skin: Wear sunscreen and protective clothing when outdoors, as this medication can make your skin more sensitive to sunburn.
  • Tell your doctor: Inform your dentist, surgeon, or any medical specialist that you are taking Trpe Plus Tablet 10's before undergoing any scheduled procedures or starting new treatments.
  • Regular checkups: Attend regular check-ups for metabolic effects (weight changes, blood sugar), liver function, eye pressure, blood count monitoring and the risk of blood disorders and movement assessment during long-term use.
  • Impaired memory: Trihexyphenidyl may impair memory or concentration, especially in elderly patients, and should be used at the lowest effective dose. 

verifiedApollotooltip

Inform your doctor if you are taking any of the following medicines, as they may interact.

  • Central nervous system depressants: For example, sleeping pills, strong pain relievers, or muscle relaxants can cause extreme drowsiness and slow breathing.
  • Anticholinergic medications or certain allergy remedies: They can increase the risk of dry mouth, severe constipation, and difficulty urinating.
  • Other medications: For example, certain antihistamines and antiarrhythmics have a risk of QT prolongation. Consult your doctor.

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verifiedApollotooltip
  • Alcohol: It is best to avoid alcohol, which can severely increase drowsiness, dizziness, and coordination issues, elevating your risk of accidents.

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Habit Forming

No

Therapeutic Class

[ANTIPSYCHOTICS]

FAQs

Trpe Plus Tablet 10's is used to prevent and treat schizophrenia (a mental illness). Additionally, it may be used for anxiety and depression over a short period.
Trpe Plus Tablet 10's contains Trifluoperazine and Trihexyphenidyl. Trifluoperazine is a typical antipsychotic which works by blocking the action of a chemical messenger (dopamine) in the brain that affects thoughts and mood. However, it may cause side effects such as involuntary movements (shaking of hands, muscle spasms). Trihexyphenidyl is used to treat and prevent side effects such as involuntary movements (shaking of hands, muscle spasms) caused by Trifluoperazine.
Dry mouth could be a side-effect of Trpe Plus Tablet 10's. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might help in stimulating saliva and thereby prevents drying of the mouth.
Antidepressants should be avoided while taking Trpe Plus Tablet 10's as it might increase sedative effects. Consult your doctor before taking Trpe Plus Tablet 10's if you are using depressants.
Trpe Plus Tablet 10's can cause decreased sweating which results in rising in body temperature (hyperthermia). This serious side effect is greater in hot weather so it is advisable to drink plenty of water fluids, especially in summer. However, kidney patients should consult a doctor before drinking any fluid.
Hallucination is a medical condition in which the person may feel, hear or believe things that are not true, see things that are not there, feel unusually suspicious or confused. Trihexyphenidyl in Trpe Plus Tablet 10's may cause hallucination in some cases if taken for a prolonged time. So, if you experience hallucinations while taking Trpe Plus Tablet 10's, please talk to your doctor immediately.
Trpe Plus Tablet 10's should be avoided by dementia (decline in memory, behaviour, thinking and ability to do daily activities) patients as it may increase the risk of severe adverse effects. Therefore, inform your doctor if you are suffering from dementia before taking Trpe Plus Tablet 10's.
Though Trpe Plus Tablet 10's starts working within a few hours, it might take 2-3 weeks to notice the full benefits. Keep taking Trpe Plus Tablet 10's for the prescribed duration for effective treatment.
No, you should not stop taking Trpe Plus Tablet 10's even though you feel better as it may cause withdrawal symptoms. Consult the doctor if you experience any difficulties while taking Trpe Plus Tablet 10's; the doctor might lower the dose gradually.
Trpe Plus Tablet 10's does not cause sleepiness. However, it may cause sleepiness if you take alcohol with Trpe Plus Tablet 10's. Therefore, avoid consuming alcohol while taking Trpe Plus Tablet 10's. Trpe Plus Tablet 10's might cause dizziness and drowsiness in some people. Avoid driving or operating machinery if you experience these symptoms.
Trpe Plus Tablet 10's can be stored in a cool and dry place away from sunlight. Keep it out of sight and reach of children.
The side effects of Trpe Plus Tablet 10's include dizziness, nausea, abdominal pain, blurred vision, constipation, decreased blood pressure, urine retention, dry mouth, weight gain, and excessive sweating. Consult the doctor if any of these side effects persist or worsen.
It is highly recommended to avoid alcohol while taking Trpe Plus Tablet 10's. Alcohol can increase side effects like dizziness, confusion, and extreme sleepiness, which can be dangerous. Talk to your doctor if you have concerns.
Some people may experience dizziness or lightheadedness when rising from a sitting or lying position. To prevent this, try to stand up slowly and hold onto a stable surface. Talk to your doctor if this dizziness continues.
Do not take Trpe Plus Tablet 10's if you have narrow-angle glaucoma, as it can increase the pressure inside your eyes and worsen your condition. If you have any other type of eye condition, talk to your doctor before starting this medicine.
Take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular schedule. Do not take two doses at once, and talk to your doctor or pharmacist if you are unsure.
Yes, this medication can make your skin more sensitive to direct sunlight, increasing the risk of sunburn. Wear sunscreen, protective clothing, and sunglasses when spending time outdoors, and talk to your doctor if you experience severe skin reactions.

Disclaimer

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Country of origin

India

Manufacturer/Marketer address

No.Ff-4A, Devnandan Complex, Arshi Technical Road, Ghatlodia, Ahmedabad - 380061, Gujarat , India
Other Info - TRP0015
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