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Ukoric 250 Capsule

Ukoric 250 Capsule

Prescription drug
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Manufacturer/Marketer

Uko Pharmatech Pvt Ltd

Consume Type

ORAL

Return Policy

Not Returnable

About Ukoric 250 Capsule

Ukoric 250 Capsule belongs to a class of medication called 'enzyme inhibitor', primarily used to decrease blood uric acid levels in the body. It is used to treat Gout (increased uric acid leading to inflammation), kidney stones, bladder stones. Gout is a type of inflammatory reaction (allergic reaction) to uric acid crystals that form and accumulate inside joints, especially  big toe, due to high uric acid levels in the blood resulting in immense pain in joints. 

Ukoric 250 Capsule contains allopurinol, which works by inhibiting the enzyme xanthine oxidase, the enzyme responsible for the formation of uric acid. It stops uric acid formation inside the body without affecting the essential mechanism of cells and the body. 

Take Ukoric 250 Capsule as prescribed by your doctor. You are advised to take Ukoric 250 Capsule for as long as your doctor has prescribed it for you, depending upon your medical condition. The most common side effects of Ukoric 250 Capsule are upset stomach, diarrhoea, skin rash, drowsiness. Most of these side effects of Ukoric 250 Capsule are temporary, do not require medical attention, and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor. 

Do not take Ukoric 250 Capsule if you are allergic to any of its ingredients. Ukoric 250 Capsule contains monohydrated lactose, if you are intolerant to some sugars, call your doctor before taking this drug. If you are pregnant or planning to get pregnant, are breast-feeding ask your doctor for advice before taking this medicine. Drink at least 2-3 litres of water so that you stay hydrated. For people who have kidney disease or renal dysfunction, dose adjustment is required. If you lose unexplained weight, please visit your doctor immediately.

Uses of Ukoric 250 Capsule

Treatment of Gout (increased uric acid in joints), Kidney stones, Bladder stones.

Medicinal Benefits

Ukoric 250 Capsule contains an 'enzyme inhibitor', medication, primarily used to decrease blood uric acid levels in the body. In addition to this, it is sometimes also used to treat pain caused by pancreas disease, seizures, and improve survival after bypass surgery. It also prevents the rejection of a kidney transplant. Ukoric 250 Capsule contains allopurinol, an enzyme inhibitor primarily used to decrease blood uric acid levels in the body. It works by inhibiting the enzyme xanthine oxidase, the enzyme responsible for the formation of uric acid. It stops uric acid formation inside the body without affecting the essential mechanism of cells and the body.

Directions for Use

Take Ukoric 250 Capsule with or without food as directed by your physician. Swallow it as a whole with a glass of water. Do not crush, chew, or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Ukoric 250 Capsule

  • Upset stomach
  • Diarrhea
  • Nausea
  • Skin rash
  • Drowsiness
  • Feeling or being sick

Drug Warnings

Do not take Ukoric 250 Capsule if you are allergic to any of its ingredients. Ukoric 250 Capsule contains monohydrated lactose; if your doctor mentioned that you are intolerant to some sugars, call your doctor before taking this drug. If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor for advice before taking this medicine, you have heart problems or high blood pressure and you take diuretics and/or a medicine called ACE-inhibitors, you have thyroid problems. In rare cases, Ukoric 250 Capsule can cause bone marrow depression, especially in patients who are already taking that can cause bone marrow depression. For people who have kidney disease or renal dysfunction, dose adjustment is required. If you lose unexplained weight, please visit your doctor immediately. Ukoric 250 Capsule can cause drowsiness so do not operate machinery or car as it can impair judgment.

Drug Interactions

Drug-Drug Interaction: Ukoric 250 Capsule is known to interact with a blood thinner (aspirin),  antihypertensive medicines (captopril), anti-bacterial medicines (ampicillin and amoxicillin), medicines used to thin the blood (dicoumarol, phenprocoumon, warfarin), anti-diabetic medicines (chlorpropamide, tolbutamide), anti-epilepsy medicines (phenytoin, carbamazepine), medicines used for chemotherapy (azathioprine, mercaptopurine, cyclophosphamide), immune suppressant medicine (cyclosporine), asthma medicines (theophylline).

Drug-Food Interaction: Ukoric 250 Capsule is known to interact with alcohol.

Drug-Disease Interaction: Ukoric 250 Capsule is known to interact in kidney or liver problems, hypertension (high blood pressure), heart problem, thyroid problems, chemotherapy.

Drug-Drug Interactions Checker List

  • ASPIRIN
  • CAPTOPRIL
  • AMPICILLIN
  • AMOXICILLIN
  • DICOUMAROL
  • PHENPROCOUMON
  • WARFARIN
  • CHLORPROPAMIDE
  • TOLBUTAMIDE
  • PHENYTOIN
  • CARBAMAZEPINE
  • AZATHIOPRINE
  • MERCAPTOPURINE
  • CYCLOPHOSPHAMIDE
  • CYCLOSPORINE
  • THEOPHYLLINE

Habit Forming

No

Diet & Lifestyle Advise

  • Purines are found in certain foods such as alcohol, fish, meat, bacon. People with gout should restrict or avoid them greatly.

  • Losing weight helps lower the levels of uric acid.

  • It is also beneficial to drink plenty of fluids. However, the restricted use of alcohol and tobacco is recommended, raising the levels of uric acid.

  • Maintain a diet that is rich in fruits, vegetables, whole grains, and low-fat dairy products.

Special Advise

  • Drink at least 8 glasses of water or other fluids each day while taking Ukoric 250 Capsule unless directed to do otherwise by your doctor. If you are a kidney patient consult a doctor before any fluid intake. 

  • If you are intolerant to sugars, please mention your doctor before starting Ukoric 250 Capsule.

  • The doctor will monitor your kidney function constantly before and during you take Ukoric 250 Capsule.

  • A liver function test should be done regularly to monitor liver enzymes as Ukoric 250 Capsule can cause liver enzyme fluctuations.

Disease/Condition Glossary

Gout: It is a type of inflammatory (allergic reaction) to uric acid crystals that form and accumulate inside feet, knuckles, and surrounding bone joints due to high uric acid levels in the blood, resulting in immense pain in joints. The pain may be severe, but the condition improves with medication. To avoid bone and cartilage damage and weakening of the kidneys, repeated gout attacks can require long-term medication. In areas such as the wrists, elbows, feet, or earlobes, chronic gout sufferers can feel small hard lumps forming over time in the soft flesh. These deposits are concentrations of uric acid crystals, called tophi, and over time can cause pain and stiffness. 

Kidney stones: It is a problem in which hard deposits occur in the kidney leading to stones. A kidney stone comprises mainly four types of calcium oxalate, uric acid, struvite and cystine. It is due to the increased level of uric acid in the body. As a result, uric acid crystals start depositing in the kidney, known as renal calculi/nephrolithiasis/urolithiasis.

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Alcohol

Unsafe

Ukoric 250 Capsule should not be taken along with alcohol as it increases uric acid levels.

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Pregnancy

Caution

Ukoric 250 Capsule is a Category C pregnancy drug. If you are pregnant, think you may be pregnant or are planning to have a baby, ask your doctor for advice before taking this medicine.

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Breast Feeding

Unsafe

Ukoric 250 Capsule is excreted in human breast milk, so it is not recommended during breastfeeding.

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Driving

Unsafe

Ukoric 250 Capsule may make some people feel drowsy or sleepy. Do not drive or operate dangerous machinery if you are affected.

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Liver

Caution

Ukoric 250 Capsule to be taken with caution, especially if you have a history of Liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Ukoric 250 Capsule to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Unsafe

Ukoric 250 Capsule hasn’t been studied and shouldn’t be used in people younger than 18 years to treat gout or kidney stones.

Country of origin

India
Other Info -

Author Details

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FAQs

Ukoric 250 Capsule is used to treat Gout (increased uric acid leading to inflammation), kidney stones, and bladder stones. It decreases blood uric acid levels in the body.
Ukoric 250 Capsule contains allopurinol, an enzyme inhibitor that works by inhibiting the enzyme xanthine oxidase, the enzyme responsible for uric acid formation. It stops uric acid formation inside the body without affecting the essential mechanism of cells and the body. 
If you are taking Ukoric 250 Capsule and it makes you vomit, then your contraceptive pill would not be effective, and it could lead to unwanted pregnancy. If you are of childbearing age, inform your doctor before starting Ukoric 250 Capsule and use another form of contraceptive like condoms.
Initially, when you start Ukoric 250 Capsule, it can increase the number of gout attacks. Please do not stop taking Ukoric 250 Capsule on having an acute attack (sudden attack) of gout as it can make the attack even worse. Co-administration with an anti-inflammatory agent (colchicine) is recommended and slowly increasing the dose of Ukoric 250 Capsule.
Generally, when Ukoric 250 Capsule is given to elderly patients (above 65 years), the dose is lowered depending upon the patient's condition. Also, if mention all underlining disease you suffer from which could affect Ukoric 250 Capsule, the dose will be adjusted accordingly by your doctor
Yes, Ukoric 250 Capsule can cause drowsiness in some people. It can even make you feel dizzy or have a problem with coordination. It is advisable to avoid driving or operate machinery to avoid any unpleasant side effects.
No, Ukoric 250 Capsule is not an anti-inflammatory medicine. It works by inhibiting the enzyme xanthine oxidase, the enzyme responsible for the formation of uric acid. It stops uric acid formation inside the body without affecting the essential mechanism of cells and the body. 
It may take several weeks to lower the uric acid levels, before you start feeling better or notice any significant reduction in attacks of gout.

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